Strain Name:
C57BL/6J-MtgxR1108Btlr/Mmmh
Stock Number:
039181-MU
Citation ID:
RRID:MMRRC_039181-MU
Other Names:
R1108 (G1), C57BL/6J-MtgxR1108Btlr
Major Collection:

Gene Information

Atrn
Name: attractin
Synonyms: Mgca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11990
HGNC: HGNC:885
Homologene: 22542
Calb2
Name: calbindin 2
Synonyms: calretinin, CR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12308
HGNC: HGNC:1435
Homologene: 1318
Esrrb
Name: estrogen related receptor, beta
Synonyms: Estrrb, ERRb, ERR2, Err2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 26380
HGNC: HGNC:3473
Homologene: 69108
Ccdc93
Name: coiled-coil domain containing 93
Synonyms: 9230102M16Rik, 4633402D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70829
Homologene: 10393
Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Synonyms: trithorax Drosophila, HTRX1, ALL-1, All1, Cxxc7, Mll, Mll1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214162
HGNC: HGNC:7132
Homologene: 4338
Zik1
Name: zinc finger protein interacting with K protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22775
Homologene: 32076
Cep128
Name: centrosomal protein 128
Synonyms: 5430424K18Rik, 4930534B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 75216
Homologene: 35315
Plk2
Name: polo like kinase 2
Synonyms: Snk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20620
VEGA: 13
Homologene: 21317
Alms1
Name: ALMS1, centrosome and basal body associated
Synonyms: Alstrom syndrome 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 236266
HGNC: HGNC:428
Homologene: 49406
Macrod2
Name: mono-ADP ribosylhydrolase 2
Synonyms: 2610107G07Rik, 1110033L15Rik, 2900006F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72899
Homologene: 85987
Sema6a
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Synonyms: VIa, sema, Sema6A-1, Semaq, A730020P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 20358
Homologene: 32426
Fgf22
Name: fibroblast growth factor 22
Synonyms: 2210414E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67112
VEGA: 10
HGNC: HGNC:3679
Homologene: 10770
Pak4
Name: p21 (RAC1) activated kinase 4
Synonyms: 5730488L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70584
Homologene: 4300
Flcn
Name: folliculin
Synonyms: B430214A04Rik, BHD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216805
Homologene: 14583
Hsh2d
Name: hematopoietic SH2 domain containing
Synonyms: ALX, Hsh2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 209488
Homologene: 13142
4931408C20Rik
Name: RIKEN cDNA 4931408C20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210940
Homologene: 86827
Trank1
Name: tetratricopeptide repeat and ankyrin repeat containing 1
Synonyms: A230061D21Rik, LOC235639, C030048J01Rik, Lba1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320429
Homologene: 45845
Fras1
Name: Fraser extracellular matrix complex subunit 1
Synonyms: bl, E130113P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231470
Homologene: 23516
Myh4
Name: myosin, heavy polypeptide 4, skeletal muscle
Synonyms: MyHC-IIb, MHC2B, Myhsf, MM, MYH-2B, Minmus, Minimsc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17884
HGNC: HGNC:7574
Homologene: 123880
Rmc1
Name: regulator of MON1-CCZ1
Synonyms: 3110002H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 76482
Homologene: 8341
Man1c1
Name: mannosidase, alpha, class 1C, member 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230815
Homologene: 69303
Dtx3
Name: deltex 3, E3 ubiquitin ligase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 80904
Homologene: 12754
Teddm1a
Name: transmembrane epididymal protein 1A
Synonyms: e9-1, Epdd1, Teddm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240819
Homologene: 82370
Dytn
Name: dystrotelin
Synonyms: LOC241073
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241073
Homologene: 104042
Olfr868
Name: olfactory receptor 868
Synonyms: GA_x6K02T2PVTD-13841888-13842802, MOR145-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258552
Homologene: 74168
Svs6
Name: seminal vesicle secretory protein 6
Synonyms: MSVSP99, Svp6, SVS VI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20945
Homologene: 49347
Zfp971
Name: zinc finger protein 971
Synonyms: Etohi1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 626848
Homologene: 134324
Olfr564
Name: olfactory receptor 564
Synonyms: GA_x6K02T2PBJ9-5513635-5514627, MOR14-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258356
Homologene: 121507
2700062C07Rik
Name: RIKEN cDNA 2700062C07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 68046
VEGA: 18
Homologene: 12230
Cndp2
Name: CNDP dipeptidase 2 (metallopeptidase M20 family)
Synonyms: Pep-1, Dip-2, 0610010E05Rik, Cn2, Pep1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 66054
VEGA: 18
Homologene: 10085
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to G, chromosome 1 at 26,682,466 bp
  • T to A, chromosome 1 at 63,685,090 bp
  • T to C, chromosome 1 at 121,434,524 bp
  • T to C, chromosome 1 at 153,892,320 bp
  • T to C, chromosome 2 at 130,957,914 bp
  • T to A, chromosome 2 at 140,419,941 bp
  • T to C, chromosome 2 at 164,317,660 bp
  • C to T, chromosome 2 at 178,033,670 bp
  • T to C, chromosome 4 at 134,564,613 bp
  • G to A, chromosome 5 at 96,642,629 bp
  • G to A, chromosome 6 at 85,615,421 bp
  • G to A, chromosome 7 at 10,490,385 bp
  • A to G, chromosome 7 at 28,560,242 bp
  • G to A, chromosome 7 at 102,803,850 bp
  • G to A, chromosome 8 at 72,200,460 bp
  • T to A, chromosome 8 at 110,143,128 bp
  • A to C, chromosome 9 at 20,100,825 bp
  • G to T, chromosome 9 at 44,849,062 bp
  • A to G, chromosome 9 at 111,365,307 bp
  • T to C, chromosome 10 at 79,756,583 bp
  • T to A, chromosome 10 at 127,191,289 bp
  • A to G, chromosome 11 at 59,801,200 bp
  • T to G, chromosome 11 at 67,255,706 bp
  • G to A, chromosome 12 at 86,505,830 bp
  • T to A, chromosome 12 at 91,339,109 bp
  • A to G, chromosome 13 at 110,399,489 bp
  • G to A, chromosome 18 at 12,181,623 bp
  • A to G, chromosome 18 at 24,477,276 bp
  • A to G, chromosome 18 at 47,306,431 bp
  • A to G, chromosome 18 at 84,675,060 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1108 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039181-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.