Strain Name:
C57BL/6J-MtgxR1403Btlr/Mmmh
Stock Number:
039465-MU
Citation ID:
RRID:MMRRC_039465-MU
Other Names:
R1403 (G1), C57BL/6J-MtgxR1403Btlr
Major Collection:

Gene Information

Grm1
Name: glutamate receptor, metabotropic 1
Synonyms: rcw, nmf373, mGluR1, Grm1, Gprc1a, 4930455H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14816
HGNC: HGNC:4593
Homologene: 649
Vcan
Name: versican
Synonyms: DPEAAE, heart defect, 5430420N07Rik, hdf, PG-M, Cspg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 13003
HGNC: HGNC:2464
Homologene: 3228
Aldh7a1
Name: aldehyde dehydrogenase family 7, member A1
Synonyms: Atq1, D18Wsu181e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 110695
HGNC: HGNC:877
Homologene: 913
Cdc42se2
Name: CDC42 small effector 2
Synonyms: SPEC2, 2810404F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72729
Homologene: 41356
Dip2c
Name: disco interacting protein 2 homolog C
Synonyms: 2900024P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 208440
Homologene: 40996
Ltbp4
Name: latent transforming growth factor beta binding protein 4
Synonyms: 2310046A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 108075
HGNC: HGNC:6717
Homologene: 2645
Stk4
Name: serine/threonine kinase 4
Synonyms: Ysk3, Kas-2, sterile 20-like kinase 1, Mst1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 58231
Homologene: 55965
Ell
Name: elongation factor RNA polymerase II
Synonyms: eleven-nineteen lysine-rich leukemia gene, Men, Ell1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 13716
Homologene: 4762
Rbm27
Name: RNA binding motif protein 27
Synonyms: Psc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225432
VEGA: 18
Homologene: 35410
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: IP3R1, opt, Pcp1, wblo, Pcp-1, Ip3r, P400, InsP3R type I, Itpr-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Abca1
Name: ATP-binding cassette, sub-family A (ABC1), member 1
Synonyms: ABC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11303
HGNC: HGNC:29
Homologene: 21130
Neurl1a
Name: neuralized E3 ubiquitin protein ligase 1A
Synonyms: Neu1, Neur1, 2410129E16Rik, Rnf67, Nlz, Neurl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18011
VEGA: 19
HGNC: HGNC:7761
Homologene: 32503
Rnf126
Name: ring finger protein 126
Synonyms: 2610010O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70294
VEGA: 10
Homologene: 27024
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 2310042E16Rik, Coh1, 1810042B05Rik, C330002D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Sf3b4
Name: splicing factor 3b, subunit 4
Synonyms: SF3b49, 49kDa, Sap49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 107701
Homologene: 134086
Acsf2
Name: acyl-CoA synthetase family member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 264895
Homologene: 23519
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: Pcn, Plc, perlecan, per
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Zfp12
Name: zinc finger protein 12
Synonyms: Krox-7, Zfp-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231866
Homologene: 65328
Brca2
Name: breast cancer 2, early onset
Synonyms: Fancd1, RAB163
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12190
HGNC: HGNC:1101
Homologene: 41
Rnf44
Name: ring finger protein 44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 105239
Homologene: 8934
Gak
Name: cyclin G associated kinase
Synonyms: D130045N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231580
HGNC: HGNC:4113
Homologene: 3846
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: A2mr, b2b1554Clo, CD91
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Klb
Name: klotho beta
Synonyms: betaKlotho
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 83379
Homologene: 12820
Afap1l1
Name: actin filament associated protein 1-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 106877
Homologene: 18728
Mgam
Name: maltase-glucoamylase
Synonyms: 6030407P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232714
HGNC: HGNC:7043
Homologene: 130099
Cul9
Name: cullin 9
Synonyms: 1810035I07Rik, Parc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78309
Homologene: 56696
Agl
Name: amylo-1,6-glucosidase, 4-alpha-glucanotransferase
Synonyms: 1110061O17Rik, 9630046L06Rik, 9430004C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 77559
HGNC: HGNC:321
Homologene: 536
Arhgap29
Name: Rho GTPase activating protein 29
Synonyms: Parg1, C76601, B130017I01Rik, 6720461J18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 214137
Homologene: 3539
Got1l1
Name: glutamic-oxaloacetic transaminase 1-like 1
Synonyms: 1700083M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 76615
Homologene: 65045
Cdh7
Name: cadherin 7, type 2
Synonyms: CDH7L1, 9330156F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241201
HGNC: HGNC:1766
Homologene: 68391
Kdm7a
Name: lysine (K)-specific demethylase 7A
Synonyms: ENSMUSG00000073143, A630082K20Rik, Kdm7a, Jhdm1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 338523
Homologene: 25281
Rp1
Name: retinitis pigmentosa 1 (human)
Synonyms: mG145, Rp1h, oxygen-regulated protein 1, Orp1, Dcdc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 19888
Homologene: 4564
Lingo2
Name: leucine rich repeat and Ig domain containing 2
Synonyms: Lrrn6c, LERN3, B230217C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242384
Homologene: 17621
Sfi1
Name: Sfi1 homolog, spindle assembly associated (yeast)
Synonyms: 2310047I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 78887
Homologene: 12707
Akt3
Name: thymoma viral proto-oncogene 3
Synonyms: D930002M15Rik, Nmf350, PKB gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 23797
HGNC: HGNC:393
Homologene: 55904
Nrxn1
Name: neurexin I
Synonyms: neurexin I beta, neurexin I beta, neurexin I alpha, neurexin I alpha, A230068P09Rik, 1700062G21Rik, neurexin I alpha, neurexin I beta, alpha-latrotoxin receptor (calcium-dependent), 9330127H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18189
HGNC: HGNC:8008
Homologene: 21005
Gm17535
Name: predicted gene, 17535
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
Adam26a
Name: a disintegrin and metallopeptidase domain 26A (testase 3)
Synonyms: Adam26, Dtgn4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 13525
Homologene: 128363
Fam124b
Name: family with sequence similarity 124, member B
Synonyms: A830043J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241128
Homologene: 65263
Chil5
Name: chitinase-like 5
Synonyms: Bclp1, Chi3l7, Bclp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229687
Homologene: 132668
Nfkbiz
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
Synonyms: Mail
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 80859
Homologene: 12734
Zfp937
Name: zinc finger protein 937
Synonyms: Gm4979
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 245174
Homologene: 136215
Gm9797
Name: predicted pseudogene 9797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 100039343
VEGA: 10
Wdr77
Name: WD repeat domain 77
Synonyms: p44/MEP50, 2610312E17Rik, 2610003I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 70465
Homologene: 11466
Mrgpra9
Name: MAS-related GPR, member A9
Synonyms: EG668725, MrgA9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 668725
Homologene: 79615
Msantd4
Name: Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
Synonyms: 8430410K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 78100
Homologene: 34935
Nsmce1
Name: NSE1 homolog, SMC5-SMC6 complex component
Synonyms: 2510027N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67711
Homologene: 41672
Vwa2
Name: von Willebrand factor A domain containing 2
Synonyms: Amaco
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 240675
Homologene: 18238
Sp110
Name: Sp110 nuclear body protein
Synonyms: Ifi75, Ipr1, 5031415C07Rik, 5830484A20Rik, 52kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 109032
HGNC: HGNC:5401
Homologene: 82192
Prl7d1
Name: prolactin family 7, subfamily d, member 1
Synonyms: Plfr, PRP, PLF-RP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18814
Homologene: 7894
AC238840.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
Mterf3
Name: mitochondrial transcription termination factor 3
Synonyms: 2410017I18Rik, Mterfd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 66410
Homologene: 9310
Olfr483
Name: olfactory receptor 483
Synonyms: GA_x6K02T2PBJ9-10432095-10433042, MOR204-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258730
Homologene: 133602
Hrh3
Name: histamine receptor H3
Synonyms: Eae8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99296
HGNC: HGNC:5184
Homologene: 5232
Akr7a5
Name: aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase)
Synonyms: 0610025K21Rik, Afar
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 110198
Homologene: 2737
Dhrs7c
Name: dehydrogenase/reductase (SDR family) member 7C
Synonyms: 1110001P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 68460
Homologene: 19108
Syt15
Name: synaptotagmin XV
Synonyms: CHR10SYT, sytXV, E230025K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 319508
Homologene: 12901
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 4,346,297 bp
  • T to C, chromosome 1 at 80,213,339 bp
  • T to G, chromosome 1 at 85,579,079 bp
  • G to A, chromosome 1 at 110,061,132 bp
  • C to T, chromosome 1 at 177,131,110 bp
  • T to A, chromosome 2 at 150,238,948 bp
  • C to T, chromosome 2 at 164,100,528 bp
  • T to G, chromosome 2 at 180,102,754 bp
  • A to G, chromosome 3 at 96,173,637 bp
  • G to A, chromosome 3 at 105,967,257 bp
  • G to T, chromosome 3 at 106,018,093 bp
  • A to G, chromosome 3 at 116,782,597 bp
  • A to G, chromosome 3 at 121,973,929 bp
  • A to T, chromosome 4 at 35,709,420 bp
  • G to A, chromosome 4 at 53,059,253 bp
  • C to T, chromosome 4 at 137,540,100 bp
  • T to A, chromosome 4 at 139,318,123 bp
  • G to C, chromosome 5 at 65,348,746 bp
  • T to A, chromosome 5 at 108,591,145 bp
  • C to A, chromosome 5 at 143,244,780 bp
  • T to A, chromosome 5 at 150,542,649 bp
  • C to A, chromosome 6 at 39,151,253 bp
  • G to A, chromosome 6 at 40,666,881 bp
  • A to T, chromosome 6 at 108,389,553 bp
  • T to C, chromosome 7 at 27,329,039 bp
  • T to G, chromosome 7 at 38,867,921 bp
  • T to A, chromosome 7 at 47,235,638 bp
  • T to A, chromosome 7 at 108,103,615 bp
  • A to G, chromosome 7 at 125,467,855 bp
  • C to G, chromosome 8 at 27,200,717 bp
  • A to T, chromosome 8 at 43,569,192 bp
  • T to A, chromosome 8 at 70,591,488 bp
  • A to G, chromosome 9 at 3,035,804 bp
  • A to T, chromosome 9 at 4,384,023 bp
  • T to C, chromosome 10 at 11,080,135 bp
  • C to A, chromosome 10 at 11,609,550 bp
  • C to T, chromosome 10 at 79,760,868 bp
  • T to A, chromosome 10 at 127,581,891 bp
  • TCGC to TC, chromosome 11 at 3,146,254 bp
  • CCTCTC to CCTCTCTC, chromosome 11 at 3,177,419 bp
  • CT to CTTT, chromosome 11 at 3,177,422 bp
  • A to G, chromosome 11 at 54,720,366 bp
  • A to T, chromosome 11 at 67,811,650 bp
  • G to T, chromosome 11 at 94,562,874 bp
  • A to G, chromosome 13 at 9,553,264 bp
  • A to T, chromosome 13 at 27,709,197 bp
  • C to T, chromosome 13 at 54,682,008 bp
  • A to G, chromosome 13 at 66,929,880 bp
  • T to A, chromosome 13 at 89,688,484 bp
  • C to A, chromosome 14 at 34,221,202 bp
  • A to G, chromosome 15 at 35,709,122 bp
  • A to G, chromosome 16 at 55,816,470 bp
  • C to G, chromosome 17 at 46,522,175 bp
  • A to C, chromosome 17 at 90,643,053 bp
  • T to C, chromosome 18 at 42,317,681 bp
  • C to A, chromosome 18 at 56,559,269 bp
  • T to C, chromosome 18 at 61,741,838 bp
  • C to A, chromosome 19 at 47,253,711 bp
  • C to T, chromosome 19 at 56,881,138 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1403 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039465-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.