Strain Name:
C57BL/6J-MtgxR2019Btlr/Mmmh
Stock Number:
040028-MU
Citation ID:
RRID:MMRRC_040028-MU
Other Names:
R2019 (G1), C57BL/6J-MtgxR2019Btlr
Major Collection:

Strain Information

Pkd1
Name: polycystin 1, transient receptor potential channel interacting
Synonyms: polycystin-1, PC1, PC-1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18763
VEGA: 17
HGNC: HGNC:9008
Homologene: 250
Emx2
Name: empty spiracles homeobox 2
Synonyms: Pdo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13797
HGNC: HGNC:3341
Homologene: 3023
Upp1
Name: uridine phosphorylase 1
Synonyms: UdRPase, UPase, Up
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22271
Homologene: 2524
Trim13
Name: tripartite motif-containing 13
Synonyms: 3110001L12Rik, LEU5, Rfp2, RNF77
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66597
VEGA: 14
HGNC: HGNC:9976
Homologene: 4234
Dip2c
Name: disco interacting protein 2 homolog C
Synonyms: 2900024P20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 208440
Homologene: 40996
Prdm5
Name: PR domain containing 5
Synonyms: 6530401I24Rik, E130112L17Rik, PFM2, 4432417F03Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 70779
HGNC: HGNC:9349
Homologene: 10274
Phf3
Name: PHD finger protein 3
Synonyms: 2310061N19Rik, AU020177
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 213109
HGNC: HGNC:8921
Homologene: 9040
Wdr59
Name: WD repeat domain 59
Synonyms: 5430401O09Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 319481
Homologene: 38685
Vps39
Name: VPS39 HOPS complex subunit
Synonyms: A230065P22Rik, Vam6P, Vam6, mVam6
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269338
Homologene: 41025
Txnrd1
Name: thioredoxin reductase 1
Synonyms: TrxR1, TR1, TR alpha, TR
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 50493
VEGA: 10
Homologene: 55733
Lrpprc
Name: leucine-rich PPR-motif containing
Synonyms: Lrp130, 3110001K13Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 72416
Homologene: 32695
Rpf1
Name: ribosome production factor 1 homolog
Synonyms: 2210420E24Rik, 2310066N05Rik, Bxdc5
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70285
Homologene: 68728
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Ccdc141
Name: coiled-coil domain containing 141
Synonyms: ENSMUSG00000075261, CAMDI, 2610301F02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 545428
Homologene: 52149
Dnttip2
Name: deoxynucleotidyltransferase, terminal, interacting protein 2
Synonyms: 4930588M11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99480
Homologene: 124162
Dmbt1
Name: deleted in malignant brain tumors 1
Synonyms: CRP-[b], CRP-[a], ebnerin, hensin, vomeroglandin, Crpd, MUCLIN, gp300
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12945
HGNC: HGNC:2926
Homologene: 68990
Lgals3
Name: lectin, galactose binding, soluble 3
Synonyms: Mac-2, galectin-3, L-34, gal3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16854
HGNC: HGNC:6563
Homologene: 37608
Sla
Name: src-like adaptor
Synonyms: Slap, Slap-1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20491
Homologene: 36206
Ermard
Name: ER membrane associated RNA degradation
Synonyms: 2410011O22Rik, 2210404J11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381062
Homologene: 19936
Magel2
Name: MAGE family member L2
Synonyms: NDNL1, Mage-l2, nM15, ns7
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 27385
HGNC: HGNC:6814
Homologene: 8460
Dck
Name: deoxycytidine kinase
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13178
HGNC: HGNC:2704
Homologene: 616
Npat
Name: nuclear protein in the AT region
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244879
HGNC: HGNC:7896
Homologene: 1888
Kif3b
Name: kinesin family member 3B
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16569
HGNC: HGNC:6320
Homologene: 55849
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Piezo1
Name: piezo-type mechanosensitive ion channel component 1
Synonyms: Piezo1, Fam38a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234839
Homologene: 124356
Mgat5b
Name: mannoside acetylglucosaminyltransferase 5, isoenzyme B
Synonyms: GnT-IX
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268510
Homologene: 27821
Jag1
Name: jagged 1
Synonyms: Serrate-1, Headturner, Htu, ABE2, Ozz, Gsfabe2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16449
HGNC: HGNC:6188
Homologene: 180
Pitpnm1
Name: phosphatidylinositol transfer protein, membrane-associated 1
Synonyms: RdgB, DRES9
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18739
HGNC: HGNC:9003
Homologene: 3608
Tarbp1
Name: TAR RNA binding protein 1
Synonyms: Gm17296
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212728
Homologene: 38082
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Myo16
Name: myosin XVI
Synonyms: C230040D10Rik, Nyap3, BM140241
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244281
Homologene: 34710
Wdr95
Name: WD40 repeat domain 95
Synonyms: 4930434E21Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381693
Homologene: 124480
Tmem116
Name: transmembrane protein 116
Synonyms: 4930513P12Rik, 4930406A18Rik, C030022K24Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77462
Homologene: 12676
2610028H24Rik
Name: RIKEN cDNA 2610028H24 gene
Synonyms: ORF67
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 76964
HGNC: HGNC:1300
Homologene: 50540
Neb
Name: nebulin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Hsf5
Name: heat shock transcription factor family member 5
Synonyms: LOC327992
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327992
Homologene: 52701
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20192
Homologene: 68151
Ifngr1
Name: interferon gamma receptor 1
Synonyms: CD119, Nktar, Ifgr, Ifngr, IFN-gamma R, IFN-gammaR
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15979
HGNC: HGNC:5439
Homologene: 359
Hc
Name: hemolytic complement
Synonyms: C5a, C5, He, Hfib2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15139
HGNC: HGNC:1331
Homologene: 20412
Acss3
Name: acyl-CoA synthetase short-chain family member 3
Synonyms: LOC380660, 8430416H19Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 380660
Homologene: 11587
Or4a72
Name: olfactory receptor family 4 subfamily A member 72
Synonyms: GA_x6K02T2Q125-51020951-51020028, MOR231-12, Olfr1245
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258784
Homologene: 121560
Unc79
Name: unc-79 homolog
Synonyms: 9030205A07Rik, Mlca3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217843
Homologene: 41397
Abcc9
Name: ATP-binding cassette, sub-family C member 9
Synonyms: SUR2B, SUR2A, Sur2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20928
HGNC: HGNC:60
Homologene: 56521
Gm7247
Name: predicted gene 7247
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 638695
Ankrd48
Name: ankyrin repeat domain 48
Synonyms: 1700012M14Rik, GC3, 1700008J08Rik, Ankrd36
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76389
Homologene: 137366
Acp3
Name: acid phosphatase 3
Synonyms: PAP, A030005E02Rik, Acpp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 56318
HGNC: HGNC:125
Homologene: 55552
Slc4a10
Name: solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
Synonyms: NCBE
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94229
Homologene: 23340
Tmem30a
Name: transmembrane protein 30A
Synonyms: 2010200I23Rik, D9Wsu20e, Cdc50a
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69981
Homologene: 110703
Vmn2r79
Name: vomeronasal 2, receptor 79
Synonyms: EG621430
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 621430
Homologene: 115466
Spire2
Name: spire type actin nucleation factor 2
Synonyms: Spir-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234857
Homologene: 72212
Tbpl1
Name: TATA box binding protein-like 1
Synonyms: TLF, TRP, TRF2, Tlp
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237336
Homologene: 3577
Or5m3
Name: olfactory receptor family 5 subfamily M member 3
Synonyms: GA_x6K02T2Q125-47485813-47486745, MOR199-1, Olfr1032
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258572
Homologene: 17299
Akt1
Name: thymoma viral proto-oncogene 1
Synonyms: PKB/Akt, Akt, PKBalpha, PKB
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 11651
HGNC: HGNC:391
Homologene: 3785
Fignl1
Name: fidgetin-like 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 60530
Homologene: 11063
Tgfbrap1
Name: transforming growth factor, beta receptor associated protein 1
Synonyms: 3110018K12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 73122
Homologene: 3141
Lamp3
Name: lysosomal-associated membrane protein 3
Synonyms: Cd208, 1200002D17Rik, DC-LAMP, TSC403
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239739
VEGA: 16
Homologene: 8670
Or1j4
Name: olfactory receptor family 1 subfamily J member 4
Synonyms: GA_x6K02T2NLDC-33544602-33545540, MOR136-13, Olfr350
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258620
HGNC: HGNC:8211
Homologene: 64897
Ptgis
Name: prostaglandin I2 (prostacyclin) synthase
Synonyms: Pgi2, Pgis, Cyp8a1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19223
HGNC: HGNC:9603
Homologene: 37374
Fmn1
Name: formin 1
Synonyms: Fmn, formin-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14260
HGNC: HGNC:3768
Homologene: 121778
Parp8
Name: poly (ADP-ribose) polymerase family, member 8
Synonyms: 2810430O08Rik, D13Ertd275e
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 52552
VEGA: 13
Homologene: 11621
Itgax
Name: integrin alpha X
Synonyms: CD11C (p150) alpha polypeptide, Cd11c, CR4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16411
HGNC: HGNC:6152
Homologene: 55493
Abi3bp
Name: ABI family member 3 binding protein
Synonyms: 5033411B22Rik, D930038M13Rik, eratin, TARSH
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 320712
VEGA: 16
Homologene: 134172
Klhdc9
Name: kelch domain containing 9
Synonyms: ESTM31, 1190002J23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68874
Homologene: 66637
Adam3
Name: ADAM metallopeptidase domain 3
Synonyms: Taz83, tMDC, Cyrn1, ADAM3, Taz83
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11497
HGNC: HGNC:209
Homologene: 69052
Mtmr6
Name: myotubularin related protein 6
Synonyms: 4022440C11Rik, Gm38641
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219135
VEGA: 14
HGNC: HGNC:7453
Homologene: 55842
Efhb
Name: EF hand domain family, member B
Synonyms: 4921525D22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 211482
VEGA: 17
Homologene: 16982
F8
Name: coagulation factor VIII
Synonyms: Factor VIII, FVIII, Cf-8, Cf8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 14069
HGNC: HGNC:3546
Homologene: 49153
Irx5
Name: Iroquois homeobox 5
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 54352
Homologene: 38105
Amz1
Name: archaelysin family metallopeptidase 1
Synonyms: 6530401C20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231842
Homologene: 18290
Slc26a10
Name: solute carrier family 26, member 10
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216441
VEGA: 10
Homologene: 66953
Art2b
Name: ADP-ribosyltransferase 2b
Synonyms: Rt6-2, Rt-6, Rt6, ART2.2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11872
Homologene: 113756
Tada2b
Name: transcriptional adaptor 2B
Synonyms: LOC231151
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231151
Homologene: 51007
Rpl3l
Name: ribosomal protein L3-like
Synonyms: 1110057H16Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66211
Homologene: 68434
Phospho1
Name: phosphatase, orphan 1
Synonyms: D11Moh36
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237928
Homologene: 13330
Gpalpp1
Name: GPALPP motifs containing 1
Synonyms: 1200011I18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67467
VEGA: 14
Homologene: 10234
Prkx
Name: protein kinase, X-linked
Synonyms: Pkare
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 19108
Homologene: 55868
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 30,811,847 bp
  • A to G, chromosome 1 at 43,054,517 bp
  • T to C, chromosome 1 at 171,358,941 bp
  • A to C, chromosome 2 at 35,013,528 bp
  • A to T, chromosome 2 at 36,850,406 bp
  • G to T, chromosome 2 at 52,232,276 bp
  • A to T, chromosome 2 at 62,234,381 bp
  • C to G, chromosome 2 at 76,755,332 bp
  • A to C, chromosome 2 at 77,011,565 bp
  • A to T, chromosome 2 at 86,008,223 bp
  • A to G, chromosome 2 at 89,575,393 bp
  • G to T, chromosome 2 at 112,781,065 bp
  • A to C, chromosome 2 at 113,364,480 bp
  • T to C, chromosome 2 at 120,343,227 bp
  • C to T, chromosome 2 at 137,084,679 bp
  • A to G, chromosome 2 at 153,323,525 bp
  • A to G, chromosome 2 at 167,208,279 bp
  • G to A, chromosome 2 at 167,214,810 bp
  • T to C, chromosome 3 at 122,280,744 bp
  • T to A, chromosome 3 at 146,521,221 bp
  • T to C, chromosome 5 at 36,483,906 bp
  • A to G, chromosome 5 at 88,774,084 bp
  • A to G, chromosome 5 at 121,489,254 bp
  • G to T, chromosome 5 at 140,751,964 bp
  • A to G, chromosome 5 at 149,574,148 bp
  • C to A, chromosome 6 at 65,831,356 bp
  • G to A, chromosome 6 at 142,675,434 bp
  • G to A, chromosome 7 at 62,379,096 bp
  • G to T, chromosome 7 at 87,002,426 bp
  • T to C, chromosome 7 at 101,579,987 bp
  • A to G, chromosome 7 at 128,148,526 bp
  • T to G, chromosome 7 at 131,110,989 bp
  • T to C, chromosome 8 at 10,376,260 bp
  • A to T, chromosome 8 at 24,697,238 bp
  • T to G, chromosome 8 at 45,023,746 bp
  • T to G, chromosome 8 at 92,358,364 bp
  • A to G, chromosome 8 at 111,466,793 bp
  • A to G, chromosome 8 at 122,482,712 bp
  • T to C, chromosome 8 at 123,332,918 bp
  • C to T, chromosome 8 at 126,428,114 bp
  • A to G, chromosome 9 at 53,562,491 bp
  • T to C, chromosome 9 at 79,774,218 bp
  • C to T, chromosome 9 at 104,324,702 bp
  • A to T, chromosome 10 at 19,592,113 bp
  • T to A, chromosome 10 at 22,707,677 bp
  • C to A, chromosome 10 at 76,458,065 bp
  • G to A, chromosome 10 at 82,877,373 bp
  • C to T, chromosome 10 at 106,936,207 bp
  • C to T, chromosome 10 at 127,177,929 bp
  • A to G, chromosome 11 at 5,689,140 bp
  • A to T, chromosome 11 at 9,133,240 bp
  • T to C, chromosome 11 at 11,802,054 bp
  • C to T, chromosome 11 at 87,636,142 bp
  • G to A, chromosome 11 at 95,831,106 bp
  • A to G, chromosome 11 at 116,947,348 bp
  • G to A, chromosome 12 at 103,171,571 bp
  • T to C, chromosome 12 at 112,659,625 bp
  • A to G, chromosome 13 at 9,654,672 bp
  • C to T, chromosome 13 at 11,851,188 bp
  • G to A, chromosome 13 at 116,868,432 bp
  • T to A, chromosome 14 at 47,384,587 bp
  • A to T, chromosome 14 at 51,365,347 bp
  • T to C, chromosome 14 at 60,298,992 bp
  • T to A, chromosome 14 at 61,604,886 bp
  • A to T, chromosome 14 at 76,110,691 bp
  • T to C, chromosome 15 at 66,782,555 bp
  • A to T, chromosome 16 at 19,701,211 bp
  • A to G, chromosome 16 at 56,677,796 bp
  • C to T, chromosome 17 at 15,053,265 bp
  • T to A, chromosome 17 at 24,568,684 bp
  • A to C, chromosome 17 at 24,735,516 bp
  • A to G, chromosome 17 at 53,401,477 bp
  • A to T, chromosome 17 at 84,752,331 bp
  • T to C, chromosome 19 at 4,113,641 bp
  • A to G, chromosome 19 at 59,459,339 bp
  • T to A, chromosome X at 75,316,495 bp
  • T to C, chromosome X at 77,765,404 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2019 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040028-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.