Strain Name:
C57BL/6J-MtgxR3720Btlr/Mmmh
Stock Number:
040711-MU
Citation ID:
RRID:MMRRC_040711-MU
Other Names:
R3720 (G1), C57BL/6J-MtgxR3720Btlr
Major Collection:

Gene Information

Ldb1
Name: LIM domain binding 1
Synonyms: CLIM2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16825
HGNC: HGNC:6532
Homologene: 2891
Tns3
Name: tensin 3
Synonyms: TEM6, F830010I22Rik, Tens1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 319939
Homologene: 49713
Cstf3
Name: cleavage stimulation factor, 3' pre-RNA, subunit 3
Synonyms: 4732468G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228410
HGNC: HGNC:2485
Homologene: 1014
Fry
Name: FRY microtubule binding protein
Synonyms: cg003, 9330186A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320365
Homologene: 113770
Swap70
Name: SWA-70 protein
Synonyms: 70kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20947
Homologene: 7557
Atp2c1
Name: ATPase, Ca++-sequestering
Synonyms: SPCA, ATP2C1A, PMR1, 1700121J11Rik, D930003G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235574
Homologene: 56672
Zfp106
Name: zinc finger protein 106
Synonyms: Cd-1, H3a, sirm, Sh3bp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20402
Homologene: 40787
Iqgap2
Name: IQ motif containing GTPase activating protein 2
Synonyms: 4933417J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 544963
VEGA: 13
HGNC: HGNC:6111
Homologene: 101543
Myo1b
Name: myosin IB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17912
HGNC: HGNC:7596
Homologene: 7856
Lrmda
Name: leucine rich melanocyte differentiation associated
Synonyms: Oca7, 1700112E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 76633
Homologene: 49975
Polg
Name: polymerase (DNA directed), gamma
Synonyms: Pol gamma, polymerase gamma, mitochondrial DNA polymerase gamma, mitochondrial DNA polymerase-gamma, Polga
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18975
HGNC: HGNC:9179
Homologene: 2016
Mei1
Name: meiotic double-stranded break formation protein 1
Synonyms: mei1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 74369
Homologene: 46535
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Kirrel
Name: kirre like nephrin family adhesion molecule 1
Synonyms: Neph1, Kirrel1, 6720469N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 170643
Homologene: 10089
Med23
Name: mediator complex subunit 23
Synonyms: ESTM7, 3000002A17Rik, X83317, Crsp3, Sur2, sno
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70208
HGNC: HGNC:2372
Homologene: 3552
Appl1
Name: adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Synonyms: 7330406P05Rik, 2900057D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 72993
Homologene: 32143
Spink4
Name: serine peptidase inhibitor, Kazal type 4
Synonyms: MPGC60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 20731
Homologene: 7954
Fstl5
Name: follistatin-like 5
Synonyms: 9130207J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213262
Homologene: 10584
Trak2
Name: trafficking protein, kinesin binding 2
Synonyms: GRIF-1, CALS-C, OIP98, GRIF1, 4733401O11Rik, Als2cr3, 2900022D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70827
Homologene: 22861
Cntnap5c
Name: contactin associated protein-like 5C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 620292
VEGA: 17
Homologene: 128806
Sdk2
Name: sidekick cell adhesion molecule 2
Synonyms: 5330435L01Rik, 4632412F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237979
Homologene: 10406
Glt6d1
Name: glycosyltransferase 6 domain containing 1
Synonyms: 4933411C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71103
Homologene: 18826
Sybu
Name: syntabulin (syntaxin-interacting)
Synonyms: A830027B17Rik, Golsyn/Syntabulin, 5730410E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 319613
VEGA: 15
Homologene: 9838
Uroc1
Name: urocanase domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243537
Homologene: 76629
Tnxb
Name: tenascin XB
Synonyms: Tnx, TN-MHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 81877
Homologene: 49589
Hivep1
Name: human immunodeficiency virus type I enhancer binding protein 1
Synonyms: Cryabp1, alphaA-CRYBP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 110521
VEGA: 13
HGNC: HGNC:4920
Homologene: 1596
AU018091
Name: expressed sequence AU018091
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 245128
Homologene: 106376
Speg
Name: SPEG complex locus
Synonyms: BPEG, SPEGbeta, SPEGalpha, D1Bwg1450e, SPEG, Apeg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11790
Homologene: 55619
Pik3cg
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Synonyms: PI3Kgamma, p110gamma, PI3Kgamma, PI(3)Kgamma, 5830428L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 30955
HGNC: HGNC:8978
Homologene: 68269
Dnai1
Name: dynein axonemal intermediate chain 1
Synonyms: 1110066F04Rik, Dnaic1, b2b1526Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68922
HGNC: HGNC:2954
Homologene: 8122
Kbtbd11
Name: kelch repeat and BTB (POZ) domain containing 11
Synonyms: 4930465M17Rik, 2900016B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74901
Homologene: 28701
Rars2
Name: arginyl-tRNA synthetase 2, mitochondrial
Synonyms: PRO1992, 1500002I10Rik, Rarsl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 109093
Homologene: 5707
Atp6v0b
Name: ATPase, H+ transporting, lysosomal V0 subunit B
Synonyms: 2310024H13Rik, VMA16, Atp6f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 114143
HGNC: HGNC:861
Homologene: 2986
C9
Name: complement component 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12279
HGNC: HGNC:1358
Homologene: 74406
Gm10717
Name: predicted gene 10717
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Ccrl2
Name: chemokine (C-C motif) receptor-like 2
Synonyms: 1810047I05Rik, L-CCR, Cmkbr1l2, CCR11, Ackr5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 54199
HGNC: HGNC:1612
Homologene: 2948
Col8a1
Name: collagen, type VIII, alpha 1
Synonyms: Col8a-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12837
HGNC: HGNC:2215
Homologene: 22423
Neurl1b
Name: neuralized E3 ubiquitin protein ligase 1B
Synonyms: EG240055, Neur2, C230078M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240055
Homologene: 35443
Kif1c
Name: kinesin family member 1C
Synonyms: N-3 kinsin, D11Bwg1349e, B430105J22Rik, Orch3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16562
HGNC: HGNC:6317
Homologene: 4821
Olfr1095
Name: olfactory receptor 1095
Synonyms: GA_x6K02T2Q125-48336843-48335917, MOR179-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258725
Homologene: 28042
Pramel12
Name: PRAME like 12
Synonyms: 4732496O08Rik, Pramef8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242736
Homologene: 128393
Cd47
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
Synonyms: Itgp, 9130415E20Rik, B430305P08Rik, integrin-associated protein, IAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 16423
HGNC: HGNC:1682
Homologene: 1346
Snx31
Name: sorting nexin 31
Synonyms: 4631426E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 66696
Homologene: 23551
Olfr129
Name: olfactory receptor 129
Synonyms: MOR263-9, GA_x6K02T2PSCP-2503741-2502776
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258324
Homologene: 133641
Zfp935
Name: zinc finger protein 935
Synonyms: 8430426H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 71508
VEGA: 13
Slc35a5
Name: solute carrier family 35, member A5
Synonyms: D16Ertd450e, 1010001J06Rik, D730043G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74102
Homologene: 9930
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 51,776,346 bp
  • A to T, chromosome 1 at 58,946,245 bp
  • A to T, chromosome 1 at 75,426,782 bp
  • ACCC to ACCCC, chromosome 2 at 25,795,167 bp
  • T to C, chromosome 2 at 86,851,591 bp
  • A to G, chromosome 2 at 104,653,086 bp
  • A to C, chromosome 2 at 120,534,599 bp
  • A to T, chromosome 3 at 76,429,873 bp
  • C to T, chromosome 3 at 87,089,151 bp
  • T to A, chromosome 4 at 34,659,970 bp
  • T to A, chromosome 4 at 40,929,136 bp
  • G to A, chromosome 4 at 41,602,615 bp
  • G to A, chromosome 4 at 117,885,690 bp
  • A to G, chromosome 4 at 143,419,379 bp
  • T to C, chromosome 5 at 150,454,572 bp
  • G to A, chromosome 6 at 90,346,355 bp
  • G to T, chromosome 7 at 3,156,115 bp
  • G to A, chromosome 7 at 79,456,791 bp
  • A to G, chromosome 7 at 110,270,047 bp
  • T to A, chromosome 8 at 15,029,118 bp
  • A to G, chromosome 9 at 3,025,532 bp
  • A to T, chromosome 9 at 105,422,976 bp
  • T to C, chromosome 9 at 111,056,364 bp
  • T to C, chromosome 10 at 24,891,120 bp
  • G to A, chromosome 11 at 8,492,999 bp
  • T to C, chromosome 11 at 70,703,771 bp
  • G to A, chromosome 11 at 113,800,244 bp
  • A to G, chromosome 12 at 32,176,871 bp
  • C to T, chromosome 13 at 42,158,601 bp
  • G to A, chromosome 13 at 62,455,032 bp
  • T to C, chromosome 13 at 95,668,528 bp
  • T to A, chromosome 14 at 22,027,331 bp
  • G to A, chromosome 14 at 26,927,844 bp
  • A to G, chromosome 15 at 6,483,119 bp
  • T to C, chromosome 15 at 36,523,558 bp
  • A to G, chromosome 15 at 44,672,632 bp
  • A to G, chromosome 15 at 82,103,204 bp
  • A to T, chromosome 16 at 45,147,322 bp
  • A to G, chromosome 16 at 49,867,842 bp
  • T to C, chromosome 16 at 57,626,916 bp
  • C to T, chromosome 17 at 26,414,975 bp
  • G to A, chromosome 17 at 30,854,898 bp
  • T to A, chromosome 17 at 34,712,964 bp
  • T to C, chromosome 17 at 38,055,368 bp
  • T to C, chromosome 17 at 58,330,202 bp
  • C to T, chromosome 19 at 46,044,892 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3720 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040711-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.