Strain Name:
C57BL/6J-MtgxR3809Btlr/Mmmh
Stock Number:
040766-MU
Citation ID:
RRID:MMRRC_040766-MU
Other Names:
R3809 (G1), C57BL/6J-MtgxR3809Btlr
Major Collection:

Strain Information

Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: E330008K23Rik, HALR, Mll3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231051
Homologene: 46480
Cacna1g
Name: calcium channel, voltage-dependent, T type, alpha 1G subunit
Synonyms: a1G, Cav3.1d
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12291
HGNC: HGNC:1394
Homologene: 22544
Ip6k1
Name: inositol hexaphosphate kinase 1
Synonyms: InsP6, 1200016D08Rik, Ihpk1, InsP6k1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 27399
Homologene: 56602
Hdac1
Name: histone deacetylase 1
Synonyms: RPD3, HD1, MommeD5
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 433759
HGNC: HGNC:4852
Homologene: 68426
Ppp4c
Name: protein phosphatase 4, catalytic subunit
Synonyms: PPX, 1110002D08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56420
HGNC: HGNC:9319
Homologene: 2038
Pfdn1
Name: prefoldin 1
Synonyms: 2700086I23Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 67199
VEGA: 18
HGNC: HGNC:8866
Homologene: 37644
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: Megalin, Gp330, D230004K18Rik, b2b1625.2Clo
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Plcd3
Name: phospholipase C, delta 3
Synonyms: 2610205J15Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72469
HGNC: HGNC:9061
Homologene: 14858
Arhgap12
Name: Rho GTPase activating protein 12
Synonyms: 2810011M08Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 75415
Homologene: 23089
Slc2a3
Name: solute carrier family 2 (facilitated glucose transporter), member 3
Synonyms: Glut-3, Glut3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20527
Homologene: 74302
Brd4
Name: bromodomain containing 4
Synonyms: MCAP, HUNK1, WI-11513
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 57261
Homologene: 136213
Sik3
Name: SIK family kinase 3
Synonyms: 5730525O22Rik, 9030204A07Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70661
Homologene: 57023
Lin9
Name: lin-9 DREAM MuvB core complex component
Synonyms: 2700022J23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 72568
Homologene: 35252
Trip11
Name: thyroid hormone receptor interactor 11
Synonyms: 3110031G15Rik, 2610511G22Rik, 6030460N08Rik, TRIP230, GMAP-210
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 109181
Homologene: 20897
Sec16a
Name: SEC16 homolog A, endoplasmic reticulum export factor
Synonyms: C230052J16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227648
Homologene: 10533
Med15
Name: mediator complex subunit 15
Synonyms: A230074L19Rik, Pcqap
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 94112
VEGA: 16
Tspan5
Name: tetraspanin 5
Synonyms: NET-4, 4930505M03Rik, 2810455A09Rik, Tm4sf9
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56224
Homologene: 4182
Pfas
Name: phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
Synonyms: 4432409B16Rik, Sofa
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237823
HGNC: HGNC:8863
Homologene: 5970
Zfp592
Name: zinc finger protein 592
Synonyms: A730014M16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233410
Homologene: 8759
Cog1
Name: component of oligomeric golgi complex 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16834
HGNC: HGNC:6545
Homologene: 8411
Paxip1
Name: PAX interacting (with transcription-activation domain) protein 1
Synonyms: PTIP, D5Ertd149e
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 55982
HGNC: HGNC:8624
2700049A03Rik
Name: RIKEN cDNA 2700049A03 gene
Synonyms: talpid3, Ta3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76967
Homologene: 8839
Baz2b
Name: bromodomain adjacent to zinc finger domain, 2B
Synonyms: D2Ertd794e, 5830435C13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 407823
HGNC: HGNC:963
Homologene: 8394
Cd209b
Name: CD209b antigen
Synonyms: SIGNR1, mSIGNR1, 1810030I22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 69165
Homologene: 84858
Mgat5b
Name: mannoside acetylglucosaminyltransferase 5, isoenzyme B
Synonyms: GnT-IX
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268510
Homologene: 27821
Frmd4b
Name: FERM domain containing 4B
Synonyms: 6030440G05Rik, GRSP1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232288
Homologene: 14916
Itga11
Name: integrin alpha 11
Synonyms: 4732459H24Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 319480
HGNC: HGNC:6136
Homologene: 8151
Hps3
Name: HPS3, biogenesis of lysosomal organelles complex 2 subunit 1
Synonyms: Hermansky-Pudlak syndrome 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12807
Homologene: 13019
Tent4a
Name: terminal nucleotidyltransferase 4A
Synonyms: LAK-1, TRF4, TRF4-1, Pols, Papd7
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 210106
Homologene: 5089
F5
Name: coagulation factor V
Synonyms: Cf-5, Cf5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Aoc1l3
Name: amine oxidase copper containing 1-like 3
Synonyms: SVS I, Svs1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243377
HGNC: HGNC:80
Homologene: 18250
Celsr2
Name: cadherin, EGF LAG seven-pass G-type receptor 2
Synonyms: mfmi1, flamingo, EGFL2, Adgrc2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 53883
HGNC: HGNC:3231
Homologene: 1078
Neb
Name: nebulin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Armc3
Name: armadillo repeat containing 3
Synonyms: 4921513G22Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70882
Homologene: 31589
Col6a6
Name: collagen, type VI, alpha 6
Synonyms: E330026B02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245026
Homologene: 18260
Ucp1
Name: uncoupling protein 1 (mitochondrial, proton carrier)
Synonyms: Slc25a7
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 22227
Homologene: 22524
Tram2
Name: translocating chain-associating membrane protein 2
Synonyms: C330003D03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 170829
Homologene: 8183
Gm10033
Name: predicted gene 10033
Synonyms: E230024E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 378466
Or2a25
Name: olfactory receptor family 2 subfamily A member 25
Synonyms: GA_x6K02T2P3E9-4647978-4647046, MOR261-1, Olfr447
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258990
Homologene: 17457
Or4c112
Name: olfactory receptor family 4 subfamily C member 112
Synonyms: GA_x6K02T2Q125-50504545-50503631, MOR233-4, Olfr1217
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258903
Homologene: 73985
Tinag
Name: tubulointerstitial nephritis antigen
Synonyms: TIN-ag
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 26944
Homologene: 8082
3425401B19Rik
Name: RIKEN cDNA 3425401B19 gene
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100504518
VEGA: 14
Homologene: 54908
Wipf3
Name: WAS/WASL interacting protein family, member 3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330319
Homologene: 113391
Ublcp1
Name: ubiquitin-like domain containing CTD phosphatase 1
Synonyms: 8430435I17Rik, 4930527B16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 79560
Homologene: 16796
Cntnap3
Name: contactin associated protein-like 3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238680
VEGA: 13
Homologene: 129602
Hlf
Name: hepatic leukemia factor
Synonyms: E230015K02Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217082
HGNC: HGNC:4977
Homologene: 31074
Eif2b4
Name: eukaryotic translation initiation factor 2B, subunit 4 delta
Synonyms: Eif2b
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13667
HGNC: HGNC:3260
Homologene: 5976
Pgghg
Name: protein glucosylgalactosylhydroxylysine glucosidase
Synonyms: 5730511L01Rik, Athl1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212974
Homologene: 16023
Plekha8
Name: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
Synonyms: FAPP2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 231999
Homologene: 32284
Kcnj12
Name: potassium inwardly-rectifying channel, subfamily J, member 12
Synonyms: Kir2.2, IRK2, MB-IRK2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16515
Homologene: 7793
Ctnna2
Name: catenin alpha 2
Synonyms: alpha(N)-catenin, alpha N-catenin, Catna, chp, Catna2, catenin (cadherin associated protein), alpha 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12386
HGNC: HGNC:2510
Homologene: 68394
Fstl1
Name: follistatin-like 1
Synonyms: TSC-36
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 14314
HGNC: HGNC:3972
Homologene: 5144
Slamf1
Name: signaling lymphocytic activation molecule family member 1
Synonyms: IPO-3, CD150, ESTM51, CDw150, Slam
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 27218
Homologene: 48162
Rnf217
Name: ring finger protein 217
Synonyms: Ibrdc1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 268291
Homologene: 66368
Or8b3b
Name: olfactory receptor family 8 subfamily B member 3B
Synonyms: GA_x6K02T2PVTD-32375756-32374818, MOR164-3, Olfr918
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258372
VEGA: 9
Klhdc3
Name: kelch domain containing 3
Synonyms: 1300011D16Rik, Peas
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71765
VEGA: 17
Homologene: 14290
Rassf2
Name: Ras association (RalGDS/AF-6) domain family member 2
Synonyms: 3830431H01Rik, 9030412M04Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 215653
HGNC: HGNC:9883
Homologene: 22840
Apol7e
Name: apolipoprotein L 7e
Synonyms: ENSMUSG00000071716
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 666348
VEGA: 15
HGNC: HGNC:619
Homologene: 40940
Ugt1a7c
Name: UDP glucuronosyltransferase 1 family, polypeptide A7C
Synonyms: A10'
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 394432
Homologene: 136043
Csf1r
Name: colony stimulating factor 1 receptor
Synonyms: CSF-1R, M-CSFR, CD115, Fim-2, Fms, Csfmr, Fim2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12978
HGNC: HGNC:2433
Homologene: 3817
Gdf1
Name: growth differentiation factor 1
Synonyms: Gdf-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14559
HGNC: HGNC:4214
Homologene: 105644
Or14j6
Name: olfactory receptor family 14 subfamily J member 6
Synonyms: MOR218-7, GA_x6K02T2PSCP-2354126-2355093, Olfr127
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258374
Homologene: 134080
Or56b1
Name: olfactory receptor family 56 subfamily B member 1
Synonyms: GA_x6K02T2PBJ9-7263864-7264823, MOR40-13, Olfr657
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258309
Homologene: 17189
Iqcf1
Name: IQ motif containing F1
Synonyms: 1700055J15Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74267
Homologene: 45119
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 21,003,995 bp
  • C to T, chromosome 1 at 88,095,382 bp
  • A to T, chromosome 1 at 164,183,004 bp
  • A to G, chromosome 1 at 171,798,177 bp
  • A to G, chromosome 1 at 180,659,111 bp
  • G to T, chromosome 2 at 19,300,665 bp
  • G to C, chromosome 2 at 26,441,813 bp
  • A to G, chromosome 2 at 52,256,789 bp
  • A to T, chromosome 2 at 59,968,896 bp
  • T to C, chromosome 2 at 69,501,548 bp
  • G to T, chromosome 2 at 89,023,426 bp
  • T to C, chromosome 2 at 131,998,260 bp
  • A to T, chromosome 3 at 20,018,812 bp
  • G to A, chromosome 3 at 108,403,239 bp
  • G to A, chromosome 3 at 138,894,523 bp
  • A to G, chromosome 4 at 129,524,320 bp
  • A to G, chromosome 5 at 25,287,693 bp
  • T to C, chromosome 5 at 25,409,138 bp
  • A to G, chromosome 5 at 27,772,029 bp
  • A to G, chromosome 5 at 31,191,168 bp
  • A to T, chromosome 6 at 42,912,337 bp
  • C to T, chromosome 6 at 48,987,994 bp
  • A to G, chromosome 6 at 54,481,795 bp
  • C to A, chromosome 6 at 54,619,349 bp
  • A to T, chromosome 6 at 76,954,757 bp
  • G to A, chromosome 6 at 97,323,729 bp
  • A to G, chromosome 6 at 122,732,429 bp
  • G to A, chromosome 7 at 81,024,532 bp
  • A to T, chromosome 7 at 104,636,333 bp
  • C to T, chromosome 7 at 126,787,327 bp
  • T to C, chromosome 7 at 140,945,295 bp
  • T to C, chromosome 8 at 3,925,347 bp
  • A to T, chromosome 8 at 69,372,608 bp
  • A to G, chromosome 8 at 70,330,010 bp
  • C to A, chromosome 8 at 83,290,641 bp
  • C to T, chromosome 9 at 38,672,863 bp
  • A to G, chromosome 9 at 46,219,486 bp
  • A to G, chromosome 9 at 62,771,382 bp
  • C to T, chromosome 9 at 76,951,905 bp
  • C to G, chromosome 9 at 105,780,692 bp
  • T to C, chromosome 9 at 106,501,878 bp
  • T to A, chromosome 9 at 108,045,887 bp
  • T to A, chromosome 10 at 31,503,808 bp
  • A to G, chromosome 11 at 44,458,282 bp
  • A to G, chromosome 11 at 61,070,277 bp
  • T to C, chromosome 11 at 68,989,953 bp
  • T to C, chromosome 11 at 90,388,103 bp
  • T to C, chromosome 11 at 94,416,096 bp
  • T to C, chromosome 11 at 103,101,383 bp
  • G to T, chromosome 11 at 113,655,010 bp
  • T to C, chromosome 11 at 116,919,553 bp
  • G to T, chromosome 12 at 71,164,546 bp
  • A to T, chromosome 12 at 71,164,547 bp
  • A to G, chromosome 12 at 101,887,029 bp
  • A to G, chromosome 13 at 64,781,804 bp
  • A to G, chromosome 13 at 69,512,996 bp
  • T to C, chromosome 14 at 32,663,693 bp
  • A to T, chromosome 15 at 77,718,062 bp
  • C to T, chromosome 16 at 17,655,734 bp
  • T to A, chromosome 16 at 37,826,751 bp
  • T to A, chromosome 17 at 32,211,270 bp
  • T to C, chromosome 17 at 37,903,573 bp
  • T to A, chromosome 17 at 46,677,932 bp
  • A to T, chromosome 18 at 6,037,057 bp
  • C to T, chromosome 18 at 36,451,092 bp
  • T to A, chromosome 18 at 61,112,764 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3809 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040766-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.