Strain Name:
C57BL/6J-MtgxR4686Btlr/Mmmh
Stock Number:
041937-MU
Citation ID:
RRID:MMRRC_041937-MU
Other Names:
R4686 (G1), C57BL/6J-MtgxR4686Btlr
Major Collection:

Gene Information

Nos2
Name: nitric oxide synthase 2, inducible
Synonyms: iNOS, Nos-2, NOS-II, Nos2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18126
HGNC: HGNC:7873
Homologene: 55473
Hspa12a
Name: heat shock protein 12A
Synonyms: Hspa12a, 1700063D12Rik, Gm19925
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 73442
VEGA: 19
Homologene: 18422
Topors
Name: topoisomerase I binding, arginine/serine-rich
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 106021
Homologene: 4237
Ociad1
Name: OCIA domain containing 1
Synonyms: expressed during mesenchymal induction 2, Emi2, B230209J16Rik, 6030432N09Rik, TPA018, Asrij, Imi2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68095
Homologene: 9866
Arhgap21
Name: Rho GTPase activating protein 21
Synonyms: 5530401C11Rik, ARHGAP10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71435
Homologene: 10822
Tpx2
Name: TPX2, microtubule-associated
Synonyms: REPP86, DIL2, p100, 2610005B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72119
HGNC: HGNC:1249
Homologene: 8107
Copb1
Name: coatomer protein complex, subunit beta 1
Synonyms: Copb1, 2610019B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70349
HGNC: HGNC:2231
Homologene: 5664
Cse1l
Name: chromosome segregation 1-like (S. cerevisiae)
Synonyms: Cas, Capts, 2610100P18Rik, Xpo2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 110750
HGNC: HGNC:2431
Homologene: 1006
Thoc1
Name: THO complex 1
Synonyms: 3110002N20Rik, NMP-84
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225160
VEGA: 18
Homologene: 38012
Iqgap2
Name: IQ motif containing GTPase activating protein 2
Synonyms: 4933417J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 544963
VEGA: 13
HGNC: HGNC:6111
Homologene: 101543
Trim24
Name: tripartite motif-containing 24
Synonyms: Tif1a, A130082H20Rik, D430004I05Rik, TIF1alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 21848
Homologene: 20830
Adnp
Name: activity-dependent neuroprotective protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11538
Homologene: 7617
Lamp5
Name: lysosomal-associated membrane protein family, member 5
Synonyms: 3110035N03Rik, BAD-LAMP, 6330527O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76161
Homologene: 8173
Srp68
Name: signal recognition particle 68
Synonyms: 2610024I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217337
Homologene: 7056
Zfp740
Name: zinc finger protein 740
Synonyms: 1110034O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 68744
Homologene: 129530
Mlec
Name: malectin
Synonyms: ESTM19, 2410014A08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 109154
Homologene: 8823
Runx2
Name: runt related transcription factor 2
Synonyms: AML3, polyomavirus enhancer binding factor 2 (PEBP2), SL3-3 enhancer factor 1, PEBP2 alpha A, PEBP2aA, Osf2, Cbfa1, Pebpa2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12393
Homologene: 68389
Nceh1
Name: neutral cholesterol ester hydrolase 1
Synonyms: CPO-BP, mKIAA1363, B230106I24Rik, Aadacl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 320024
Homologene: 23251
Flt3
Name: FMS-like tyrosine kinase 3
Synonyms: CD135, Flk-2, Flt-3, Flk2, wmfl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14255
HGNC: HGNC:3765
Homologene: 3040
Akap6
Name: A kinase (PRKA) anchor protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238161
VEGA: 12
HGNC: HGNC:376
Homologene: 3157
Kcnq1
Name: potassium voltage-gated channel, subfamily Q, member 1
Synonyms: KVLQT1, Kcna9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16535
HGNC: HGNC:6294
Homologene: 85014
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Ip3r2, Itpr5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Pcdh7
Name: protocadherin 7
Synonyms: BH-protocadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54216
HGNC: HGNC:8659
Homologene: 36101
Ccdc175
Name: coiled-coil domain containing 175
Synonyms: 4930403N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 73936
VEGA: 12
Homologene: 79144
Efcab7
Name: EF-hand calcium binding domain 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230500
Homologene: 19952
Hc
Name: hemolytic complement
Synonyms: C5a, C5, He, Hfib2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 15139
HGNC: HGNC:1331
Homologene: 20412
Vmn2r88
Name: vomeronasal 2, receptor 88
Synonyms: V2r13, V2r3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 669149
Homologene: 129606
Myf6
Name: myogenic factor 6
Synonyms: MRF4, herculin, bHLHc4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 17878
VEGA: 10
HGNC: HGNC:7566
Homologene: 1850
Hivep1
Name: human immunodeficiency virus type I enhancer binding protein 1
Synonyms: Cryabp1, alphaA-CRYBP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 110521
VEGA: 13
HGNC: HGNC:4920
Homologene: 1596
Il10ra
Name: interleukin 10 receptor, alpha
Synonyms: mIL-10R, Il10r, CDw210
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 16154
HGNC: HGNC:5964
Homologene: 1196
Zfp276
Name: zinc finger protein (C2H2 type) 276
Synonyms: D8Ertd370e, D8Ertd377e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 57247
Homologene: 10731
Chaf1b
Name: chromatin assembly factor 1, subunit B (p60)
Synonyms: 2600017H24Rik, MPHOSPH7, CAF1, CAF-I 60 kDa subunit, CAF-1 subunit B, CAF-IP60, CAF1P60, CAF1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 110749
HGNC: HGNC:1911
Homologene: 48346
Nrxn3
Name: neurexin III
Synonyms: neurexin III beta, neurexin III alpha, neurexin III beta, neurexin III alpha, 9330112C09Rik, D12Bwg0831e, 4933401A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18191
HGNC: HGNC:8010
Homologene: 83225
Greb1l
Name: growth regulation by estrogen in breast cancer-like
Synonyms: mKIAA4095, AK220484
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 381157
Homologene: 73393
Gabrb1
Name: gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
Synonyms: Gabrb-1, B230208N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14400
HGNC: HGNC:4081
Homologene: 20221
Vmn2r108
Name: vomeronasal 2, receptor 108
Synonyms: EG627805
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627805
Homologene: 129678
Tmem132d
Name: transmembrane protein 132D
Synonyms: C630028F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243274
Homologene: 71684
Gpr141
Name: G protein-coupled receptor 141
Synonyms: Pgr13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 353346
VEGA: 13
Homologene: 18771
Pacsin2
Name: protein kinase C and casein kinase substrate in neurons 2
Synonyms: Syndapin II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 23970
VEGA: 15
HGNC: HGNC:8571
Homologene: 21414
Cdhr4
Name: cadherin-related family member 4
Synonyms: D330022A01Rik, 1700021K14Rik, Cdh29
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69398
Homologene: 82362
Stk25
Name: serine/threonine kinase 25 (yeast)
Synonyms: Ste20-like, Ysk1, 1500019J11Rik, SOK-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 59041
Homologene: 48428
Ano2
Name: anoctamin 2
Synonyms: Tmem16b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243634
HGNC: HGNC:1183
Homologene: 23221
Teddm1a
Name: transmembrane epididymal protein 1A
Synonyms: e9-1, Epdd1, Teddm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240819
Homologene: 82370
Vmn1r233
Name: vomeronasal 1 receptor 233
Synonyms: V1rf5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 171236
Homologene: 128343
Lgr5
Name: leucine rich repeat containing G protein coupled receptor 5
Synonyms: Gpr49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14160
HGNC: HGNC:4504
Homologene: 20807
Tbrg4
Name: transforming growth factor beta regulated gene 4
Synonyms: TB-12, Cpr2, 2310042P22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21379
Homologene: 31259
Olfr378
Name: olfactory receptor 378
Synonyms: GA_x6K02T2P1NL-3586282-3585338, MOR135-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 259026
Homologene: 74110
Vmn1r203
Name: vomeronasal 1 receptor 203
Synonyms: V1rh11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171270
Homologene: 110880
Ears2
Name: glutamyl-tRNA synthetase 2, mitochondrial
Synonyms: 3230401I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67417
Homologene: 6907
Rgs7bp
Name: regulator of G-protein signalling 7 binding protein
Synonyms: A930030I01Rik, R7bp, D13Bwg1146e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 52882
VEGA: 13
Homologene: 78705
Adamtsl2
Name: ADAMTS-like 2
Synonyms: A930008K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 77794
Homologene: 8798
Atp13a2
Name: ATPase type 13A2
Synonyms: 1110012E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74772
Homologene: 56940
Pus7l
Name: pseudouridylate synthase 7-like
Synonyms: 3000003F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 78895
Homologene: 12842
Tedc2
Name: tubulin epsilon and delta complex 2
Synonyms: 1600002H07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72016
Homologene: 45943
Phb2
Name: prohibitin 2
Synonyms: Bap37, Bcap37, repressor of estrogen receptor activity, REA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12034
Homologene: 5263
Iqcf6
Name: IQ motif containing F6
Synonyms: 100041096
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100041096
Homologene: 67808
Olfr912
Name: olfactory receptor 912
Synonyms: GA_x6K02T2PVTD-32283590-32284522, MOR165-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258806
VEGA: 9
Homologene: 115510
Olfr547
Name: olfactory receptor 547
Synonyms: GA_x6K02T2PBJ9-5256044-5256988, MOR31-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259083
Homologene: 17493
Npw
Name: neuropeptide W
Synonyms: LOC381073
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 381073
Homologene: 17727
Gm10384
Name: predicted gene 10384
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 100038735
VEGA: 15
Clnkos
Name: cytokine-dependent hematopoietic cell linker, opposite strand
Synonyms: 1700021O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
2410022M11Rik
Name: RIKEN cDNA 2410022M11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100503842
Gm5117
Name: predicted gene 5117
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 330731
Mir6908
Name: microRNA 6908
Synonyms: mmu-mir-6908
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 102466762
VEGA: 10
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 93,623,420 bp
  • T to A, chromosome 1 at 153,892,450 bp
  • T to C, chromosome 2 at 20,863,222 bp
  • A to G, chromosome 2 at 27,093,825 bp
  • T to C, chromosome 2 at 35,039,248 bp
  • G to A, chromosome 2 at 76,737,570 bp
  • C to T, chromosome 2 at 136,059,003 bp
  • T to C, chromosome 2 at 152,889,183 bp
  • A to G, chromosome 2 at 166,932,160 bp
  • A to C, chromosome 2 at 168,182,389 bp
  • C to T, chromosome 3 at 27,241,669 bp
  • A to T, chromosome 4 at 40,261,694 bp
  • A to G, chromosome 4 at 99,878,116 bp
  • G to A, chromosome 4 at 141,003,276 bp
  • G to A, chromosome 5 at 38,741,837 bp
  • A to G, chromosome 5 at 58,129,169 bp
  • A to G, chromosome 5 at 71,700,022 bp
  • A to G, chromosome 5 at 73,306,735 bp
  • A to G, chromosome 5 at 115,150,296 bp
  • G to T, chromosome 5 at 127,792,610 bp
  • A to G, chromosome 5 at 147,377,048 bp
  • A to G, chromosome 6 at 37,908,305 bp
  • G to A, chromosome 6 at 124,713,142 bp
  • T to G, chromosome 6 at 125,790,291 bp
  • A to G, chromosome 6 at 146,229,775 bp
  • A to G, chromosome 7 at 102,535,149 bp
  • A to G, chromosome 7 at 114,221,736 bp
  • A to G, chromosome 7 at 122,048,204 bp
  • A to T, chromosome 7 at 143,107,729 bp
  • G to A, chromosome 8 at 31,739,256 bp
  • G to C, chromosome 8 at 123,268,934 bp
  • T to A, chromosome 9 at 38,582,031 bp
  • A to G, chromosome 9 at 45,269,059 bp
  • G to T, chromosome 9 at 106,627,344 bp
  • T to C, chromosome 9 at 107,995,684 bp
  • A to T, chromosome 10 at 78,447,003 bp
  • A to G, chromosome 10 at 107,493,828 bp
  • A to G, chromosome 10 at 115,458,743 bp
  • C to T, chromosome 11 at 6,618,468 bp
  • A to G, chromosome 11 at 73,425,438 bp
  • C to A, chromosome 11 at 78,928,630 bp
  • A to T, chromosome 11 at 116,265,401 bp
  • CA to C, chromosome 12 at 52,887,623 bp
  • C to T, chromosome 12 at 72,112,278 bp
  • A to T, chromosome 12 at 89,510,651 bp
  • T to A, chromosome 13 at 19,751,781 bp
  • T to C, chromosome 13 at 22,524,358 bp
  • C to T, chromosome 13 at 42,155,850 bp
  • T to C, chromosome 13 at 95,721,609 bp
  • T to A, chromosome 13 at 104,964,089 bp
  • G to A, chromosome 14 at 51,413,339 bp
  • A to G, chromosome 14 at 56,812,161 bp
  • T to C, chromosome 15 at 36,871,653 bp
  • T to C, chromosome 15 at 83,381,775 bp
  • T to A, chromosome 15 at 94,540,211 bp
  • C to T, chromosome 15 at 102,208,749 bp
  • A to G, chromosome 16 at 93,884,584 bp
  • T to C, chromosome 17 at 20,471,374 bp
  • C to T, chromosome 17 at 20,994,106 bp
  • C to T, chromosome 17 at 24,217,888 bp
  • T to G, chromosome 17 at 24,657,412 bp
  • T to A, chromosome 17 at 44,639,685 bp
  • G to T, chromosome 18 at 9,970,312 bp
  • A to T, chromosome 18 at 10,522,112 bp
  • T to A, chromosome 19 at 58,799,749 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4686 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041937-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.