Strain Name:
C57BL/6J-MtgxR5039Btlr/Mmmh
Stock Number:
042629-MU
Citation ID:
RRID:MMRRC_042629-MU
Other Names:
R5039 (G1), C57BL/6J-MtgxR5039Btlr
Major Collection:

Gene Information

Fn1
Name: fibronectin 1
Synonyms: Fn, Fn-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14268
HGNC: HGNC:3778
Homologene: 1533
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Aclp7, Acf7, trabeculin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11426
Homologene: 136191
Blm
Name: Bloom syndrome, RecQ like helicase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12144
HGNC: HGNC:1058
Homologene: 47902
Arid4b
Name: AT rich interactive domain 4B (RBP1-like)
Synonyms: 6330417L24Rik, RBBP1L1, Rbp1l1, BRCAA1, SAP180, 6720480E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 94246
Homologene: 12847
Ylpm1
Name: YLP motif containing 1
Synonyms: A930013E17Rik, ZAP, Zap3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56531
Homologene: 87707
Gpr139
Name: G protein-coupled receptor 139
Synonyms: LOC209776, GPRg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 209776
Homologene: 45860
Polr1c
Name: polymerase (RNA) I polypeptide C
Synonyms: 40kDa, Rpo1-1, RPA40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20016
Homologene: 3586
Mllt6
Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6
Synonyms: Af17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 246198
HGNC: HGNC:7138
Homologene: 31347
Btaf1
Name: B-TFIID TATA-box binding protein associated factor 1
Synonyms: E430027O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107182
Homologene: 31978
Kifbp
Name: kinesin family binding protein
Synonyms: 2510003E04Rik, Kif1bp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 72320
Homologene: 9223
Arfgef1
Name: ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)
Synonyms: BIG1, D130059B05Rik, P200, D730028O18Rik, ARFGEP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 211673
Homologene: 4687
Anapc2
Name: anaphase promoting complex subunit 2
Synonyms: 9230107K09Rik, Emi4, Imi4, expressed during mesenchymal induction 4, APC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99152
Homologene: 8359
Ccdc18
Name: coiled-coil domain containing 18
Synonyms: 4932411G06Rik, 1700021E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 73254
Homologene: 35455
Dock4
Name: dedicator of cytokinesis 4
Synonyms: EST N28122, 6330411N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238130
VEGA: 12
Homologene: 56680
Ssb
Name: Sjogren syndrome antigen B
Synonyms: autoantigen La, SS-B, La protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20823
Homologene: 2366
Ctr9
Name: CTR9 homolog, Paf1/RNA polymerase II complex component
Synonyms: Tsbp, Sh2bp1, Tsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22083
Homologene: 40668
Cdhr1
Name: cadherin-related family member 1
Synonyms: Pcdh21, Prcad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 170677
VEGA: 14
Homologene: 13215
Slc41a3
Name: solute carrier family 41, member 3
Synonyms: SLC41A1-L2, 1010001P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71699
Homologene: 23052
Syt14
Name: synaptotagmin XIV
Synonyms: B230320I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329324
Homologene: 17719
Fam120a
Name: family with sequence similarity 120, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218236
VEGA: 13
Homologene: 8752
Etnk1
Name: ethanolamine kinase 1
Synonyms: D6Ertd3e, 1110061E11Rik, EKI1, 4930555L11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 75320
Homologene: 10240
Dnmt3l
Name: DNA (cytosine-5-)-methyltransferase 3-like
Synonyms: D6Ertd14e, ecat7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 54427
HGNC: HGNC:2980
Homologene: 8362
Rnf165
Name: ring finger protein 165
Synonyms: 2900024M11Rik, LOC225743, G630064H08Rik, Ark2c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225743
Homologene: 79757
Map2
Name: microtubule-associated protein 2
Synonyms: MAP-2, Mtap2, repro4, G1-397-34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Magi3
Name: membrane associated guanylate kinase, WW and PDZ domain containing 3
Synonyms: 6530407C02Rik, 4732496O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99470
Homologene: 26431
Ric3
Name: RIC3 acetylcholine receptor chaperone
Synonyms: E130307J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 320360
Homologene: 49772
Trpv5
Name: transient receptor potential cation channel, subfamily V, member 5
Synonyms: ECaC1, CaT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194352
HGNC: HGNC:3145
Homologene: 10520
Tnfrsf1a
Name: tumor necrosis factor receptor superfamily, member 1a
Synonyms: TNF-alpha-R1, p55, TNF-alphaR1, TNFRI, TNFalpha-R1, TNF-R1, TNF receptor alpha chain, CD120a, TNF-R-I, TNFR60, TNFAR, p55-R, Tnfr1, TNF-R55, TNFRp55
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 21937
Homologene: 828
Tet3
Name: tet methylcytosine dioxygenase 3
Synonyms: D230004J03Rik, B430006D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194388
Homologene: 35360
Abcg4
Name: ATP binding cassette subfamily G member 4
Synonyms: 6430517O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 192663
Homologene: 75179
Itgb2l
Name: integrin beta 2-like
Synonyms: pactolus, 5033406G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 16415
Pcdh10
Name: protocadherin 10
Synonyms: 6430703F07Rik, 6430521D13Rik, OL-pc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18526
Homologene: 74967
Kdm1b
Name: lysine (K)-specific demethylase 1B
Synonyms: 4632428N09Rik, Aof1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218214
Homologene: 14695
Phf8-ps
Name: PHD finger protein 8, pseudogene
Synonyms: 4921501E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74042
VEGA: 17
Homologene: 66275
Pcdh18
Name: protocadherin 18
Synonyms: PCDH68L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 73173
Homologene: 10389
Rp1l1
Name: retinitis pigmentosa 1 homolog like 1
Synonyms: Rp1hl1, Dcdc4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 271209
VEGA: 14
Homologene: 105870
Nt5e
Name: 5' nucleotidase, ecto
Synonyms: ecto-5'-nucleotidase, Nt5, 2210401F01Rik, CD73
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 23959
HGNC: HGNC:8021
Homologene: 1895
Olfr944
Name: olfactory receptor 944
Synonyms: MOR171-19, GA_x6K02T2PVTD-32914568-32915503
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258500
VEGA: 9
Homologene: 110610
Fanca
Name: Fanconi anemia, complementation group A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14087
HGNC: HGNC:3582
Homologene: 108
Axl
Name: AXL receptor tyrosine kinase
Synonyms: Tyro7, Ufo, Ark
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26362
HGNC: HGNC:905
Homologene: 7583
Myrfl
Name: myelin regulatory factor-like
Synonyms: Gm239, LOC237558
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237558
VEGA: 10
Homologene: 88588
Gm17535
Name: predicted gene, 17535
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Kcnb2
Name: potassium voltage gated channel, Shab-related subfamily, member 2
Synonyms: 9630047L19Rik, Kv2.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98741
HGNC: HGNC:6232
Homologene: 31263
Rimbp3
Name: RIMS binding protein 3
Synonyms: RIM-BP3, LOC239731, LOC385766
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239731
Homologene: 77940
Cyp2c55
Name: cytochrome P450, family 2, subfamily c, polypeptide 55
Synonyms: 2010318C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 72082
HGNC: HGNC:2620
Homologene: 133567
Ccdc17
Name: coiled-coil domain containing 17
Synonyms: 1100001F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 622665
Homologene: 77410
Gm4781
Name: predicted gene 4781
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 213051
VEGA: 10
Tial1
Name: Tia1 cytotoxic granule-associated RNA binding protein-like 1
Synonyms: TIAR, 5330433G13Rik, mTIAR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 21843
Homologene: 87796
Ccdc87
Name: coiled-coil domain containing 87
Synonyms: 4931419P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 399599
VEGA: 19
Homologene: 49531
Ndufb7
Name: NADH:ubiquinone oxidoreductase subunit B7
Synonyms: 1110002H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66916
HGNC: HGNC:7702
Homologene: 3059
Olfr960
Name: olfactory receptor 960
Synonyms: MOR224-12, GA_x6K02T2PVTD-33320043-33320987
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258276
VEGA: 9
Homologene: 17168
Gm8741
Name: predicted gene 8741
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 667636
Dnase1l1
Name: deoxyribonuclease 1-like 1
Synonyms: G4.8, Dnase1ll, 2310005K03Rik, Dnl1ll
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 69537
HGNC: HGNC:2957
Homologene: 4896
Ighv1-62-3
Name: immunoglobulin heavy variable 1-62-3
Synonyms: Gm9235
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 668549
Gm3633
Name: predicted gene 3633
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 10,199,736 bp
  • T to C, chromosome 1 at 15,709,500 bp
  • A to T, chromosome 1 at 66,438,796 bp
  • A to G, chromosome 1 at 71,609,495 bp
  • A to T, chromosome 1 at 193,026,984 bp
  • T to C, chromosome 2 at 25,274,796 bp
  • A to T, chromosome 2 at 69,866,237 bp
  • A to G, chromosome 3 at 45,381,861 bp
  • A to G, chromosome 3 at 49,754,856 bp
  • A to T, chromosome 3 at 104,105,791 bp
  • T to C, chromosome 4 at 116,598,588 bp
  • T to C, chromosome 4 at 123,511,220 bp
  • T to A, chromosome 5 at 108,158,648 bp
  • T to C, chromosome 6 at 41,675,945 bp
  • T to C, chromosome 6 at 83,375,896 bp
  • A to G, chromosome 6 at 90,626,417 bp
  • A to G, chromosome 6 at 125,360,712 bp
  • T to A, chromosome 6 at 143,195,317 bp
  • C to T, chromosome 7 at 25,785,915 bp
  • G to A, chromosome 7 at 80,505,873 bp
  • G to C, chromosome 7 at 109,038,723 bp
  • C to A, chromosome 7 at 111,042,857 bp
  • A to G, chromosome 7 at 119,144,942 bp
  • T to C, chromosome 7 at 128,443,968 bp
  • A to G, chromosome 8 at 83,571,465 bp
  • T to C, chromosome 8 at 123,284,046 bp
  • T to A, chromosome 9 at 3,035,786 bp
  • T to A, chromosome 9 at 39,218,114 bp
  • A to T, chromosome 9 at 39,623,560 bp
  • G to A, chromosome 9 at 44,281,566 bp
  • T to A, chromosome 9 at 88,363,581 bp
  • C to T, chromosome 10 at 62,578,330 bp
  • T to C, chromosome 10 at 78,052,900 bp
  • C to A, chromosome 10 at 100,396,989 bp
  • T to C, chromosome 10 at 116,822,711 bp
  • G to A, chromosome 11 at 97,669,500 bp
  • C to A, chromosome 12 at 40,817,746 bp
  • T to A, chromosome 12 at 85,015,493 bp
  • A to G, chromosome 12 at 85,042,239 bp
  • G to T, chromosome 12 at 115,461,394 bp
  • A to G, chromosome 13 at 14,187,343 bp
  • G to A, chromosome 13 at 47,077,486 bp
  • A to T, chromosome 13 at 48,910,250 bp
  • T to C, chromosome 14 at 37,079,643 bp
  • A to C, chromosome 14 at 42,639,204 bp
  • A to T, chromosome 14 at 64,031,356 bp
  • A to G, chromosome 16 at 17,213,331 bp
  • T to C, chromosome 16 at 96,425,005 bp
  • A to C, chromosome 17 at 33,067,760 bp
  • G to T, chromosome 17 at 35,336,086 bp
  • G to T, chromosome 17 at 46,247,709 bp
  • A to G, chromosome 17 at 67,745,893 bp
  • A to G, chromosome 18 at 77,462,912 bp
  • T to C, chromosome 19 at 4,840,401 bp
  • T to C, chromosome 19 at 36,990,762 bp
  • A to G, chromosome 19 at 39,038,143 bp
  • C to T, chromosome X at 74,277,038 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5039 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042629-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.