Strain Name:
C57BL/6J-MtgxR5086Btlr/Mmmh
Stock Number:
042675-MU
Citation ID:
RRID:MMRRC_042675-MU
Other Names:
R5086 (G1), C57BL/6J-MtgxR5086Btlr
Major Collection:

Strain Information

Notch3
Name: notch 3
Synonyms: N3, hpbk
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18131
HGNC: HGNC:7883
Homologene: 376
Ank2
Name: ankyrin 2, brain
Synonyms: ankyrin B, Gm4392, Ankyrin-B, Ank-2, Ankyrin-2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Inpp5d
Name: inositol polyphosphate-5-phosphatase D
Synonyms: Src homology 2 domain-containing inositol-5-phosphatase, s-SHIP, SHIP-1, SHIP, SHIP1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16331
HGNC: HGNC:6079
Homologene: 4046
Il21r
Name: interleukin 21 receptor
Synonyms: NILR
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 60504
HGNC: HGNC:6006
Homologene: 11040
Dtnb
Name: dystrobrevin, beta
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13528
HGNC: HGNC:3058
Homologene: 74875
Adsl
Name: adenylosuccinate lyase
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 11564
HGNC: HGNC:291
Homologene: 12
Arhgap21
Name: Rho GTPase activating protein 21
Synonyms: 5530401C11Rik, ARHGAP10
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71435
Homologene: 10822
Sar1a
Name: secretion associated Ras related GTPase 1A
Synonyms: 1600019H17Rik, Sara1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20224
VEGA: 10
Homologene: 90897
Tmem104
Name: transmembrane protein 104
Synonyms: C630005D06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 320534
Homologene: 9802
Zc3h7b
Name: zinc finger CCCH type containing 7B
Synonyms: Scrg3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20286
VEGA: 15
Homologene: 9735
Ago1
Name: argonaute RISC catalytic subunit 1
Synonyms: argonaute 1, Eif2c1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 236511
HGNC: HGNC:3262
Homologene: 81826
Sipa1l3
Name: signal-induced proliferation-associated 1 like 3
Synonyms: 2610511M17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74206
Homologene: 77938
Eif1
Name: eukaryotic translation initiation factor 1
Synonyms: Sui1-rs1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20918
HGNC: HGNC:3249
Homologene: 135931
Iqgap2
Name: IQ motif containing GTPase activating protein 2
Synonyms: 4933417J23Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 544963
VEGA: 13
HGNC: HGNC:6111
Homologene: 101543
Mdc1
Name: mediator of DNA damage checkpoint 1
Synonyms: NFBD1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240087
Homologene: 67092
Npepps
Name: aminopeptidase puromycin sensitive
Synonyms: Psa, MP100
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19155
HGNC: HGNC:7900
Homologene: 36199
Gpbp1l1
Name: GC-rich promoter binding protein 1-like 1
Synonyms: 5330440M15Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 77110
Homologene: 84840
Mllt3
Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
Synonyms: 2610012I03Rik, 2210011H10Rik, 3830408D16Rik, D4Ertd321e, Af9
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 70122
HGNC: HGNC:7136
Homologene: 37933
Slit2
Name: slit guidance ligand 2
Synonyms: Drad-1, E130320P19Rik, E030015M03Rik, Slil3, b2b1200.1Clo
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20563
Homologene: 3516
Gm7964
Name: predicted gene 7964
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 666170
Plekhg1
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 1
Synonyms: D10Ertd733e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 213783
Homologene: 18897
Ap1b1
Name: adaptor protein complex AP-1, beta 1 subunit
Synonyms: b2b1660Clo, Adtb1, beta-prime adaptin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11764
HGNC: HGNC:554
Homologene: 21972
Chordc1
Name: cysteine and histidine rich domain containing 1
Synonyms: 1110001O09Rik, morgana, Chp-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66917
VEGA: 9
Homologene: 8111
Mrps18a
Name: mitochondrial ribosomal protein S18A
Synonyms: 1110004O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 68565
Homologene: 32391
Tdrp
Name: testis development related protein
Synonyms: 2610019F03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72148
Homologene: 18348
Ncapg
Name: non-SMC condensin I complex, subunit G
Synonyms: 5730507H05Rik, Hcapg, MFT.M05.13
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 54392
Homologene: 44071
Sec22a
Name: SEC22 homolog A, vesicle trafficking protein
Synonyms: 1810005C06Rik, Sec22l2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 317717
Homologene: 8246
Tlr3
Name: toll-like receptor 3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 142980
Homologene: 20696
Ctnnd2
Name: catenin delta 2
Synonyms: Nprap, catenin (cadherin associated protein), delta 2, Catnd2, neurojugin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 18163
VEGA: 15
HGNC: HGNC:2516
Homologene: 55574
Cyp4f18
Name: cytochrome P450, family 4, subfamily f, polypeptide 18
Synonyms: 1810054N16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72054
Homologene: 128623
Ank1
Name: ankyrin 1, erythroid
Synonyms: pale, Ank-1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11733
HGNC: HGNC:492
Homologene: 55427
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Man2c1
Name: mannosidase, alpha, class 2C, member 1
Synonyms: 1110025H24Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73744
HGNC: HGNC:6827
Homologene: 4887
Gvin3
Name: GTPase, very large interferon inducible, family member 3
Synonyms: Gm1966
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434223
Homologene: 32708
Cpne8
Name: copine VIII
Synonyms: 1500031E20Rik, 1200003E11Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66871
Homologene: 12049
Dock10
Name: dedicator of cytokinesis 10
Synonyms: A630054M16Rik, Zizimin3, Jr5, Jr4, ZIZ3, 9330153B10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210293
Homologene: 45952
Csf1
Name: colony stimulating factor 1 (macrophage)
Synonyms: BAP025, CSF-1, Csfm, colony-stimulating factor-1, M-CSF
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12977
HGNC: HGNC:2432
Homologene: 7282
Vmn2r1
Name: vomeronasal 2, receptor 1
Synonyms: EG56544, V2r83
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56544
Homologene: 84832
Fbxo44
Name: F-box protein 44
Synonyms: Fbxo6a, FBX30, Fbx6a, FBG3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230903
Homologene: 13232
Stab1
Name: stabilin 1
Synonyms: MS-1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 192187
Homologene: 9035
Syde2
Name: synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
Synonyms: C430017H16Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 214804
Homologene: 19035
Tbc1d2b
Name: TBC1 domain family, member 2B
Synonyms: 1810061M12Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67016
Homologene: 56694
Greb1
Name: gene regulated by estrogen in breast cancer protein
Synonyms: 5730583K22Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 268527
Homologene: 8780
Plekha4
Name: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
Synonyms: PEPP1, 2410005C22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69217
Homologene: 10848
Map1a
Name: microtubule-associated protein 1 A
Synonyms: Mtap1a, Mtap-1, Mtap1, 6330416M19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17754
HGNC: HGNC:6835
Homologene: 1778
Pcdhb8
Name: protocadherin beta 8
Synonyms: Pcdhb5C, PcdhbH
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93879
HGNC: HGNC:8690
Homologene: 89038
Plekhn1
Name: pleckstrin homology domain containing, family N member 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 231002
VEGA: 4
Homologene: 12949
Vmn1r45
Name: vomeronasal 1 receptor 45
Synonyms: V1ra2, V1r2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22297
Homologene: 130651
Zfp366
Name: zinc finger protein 366
Synonyms: DC-SCRIPT
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238803
Homologene: 17637
Pcdhb7
Name: protocadherin beta 7
Synonyms: Pcdhb4B, PcdhbG
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93878
HGNC: HGNC:8689
Homologene: 87123
Gabbr2
Name: gamma-aminobutyric acid type B receptor subunit 2
Synonyms: LOC242425, Gababr2, GB2, Gpr51
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242425
HGNC: HGNC:4507
Homologene: 55902
Cdh26
Name: cadherin-like 26
Synonyms: LOC381409
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381409
Homologene: 18643
Spam1
Name: sperm adhesion molecule 1
Synonyms: Ph-20
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20690
Homologene: 7547
Zfp598
Name: zinc finger protein 598
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 213753
VEGA: 17
Homologene: 5672
Dnaaf2
Name: dynein, axonemal assembly factor 2
Synonyms: Ktu, 2810020C19Rik, 1110034A24Rik, kintoun
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 109065
Homologene: 10026
BC049715
Name: cDNA sequence BC049715
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320135
Homologene: 52193
C1ra
Name: complement component 1, r subcomponent A
Synonyms: mC1rA
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 50909
HGNC: HGNC:1246
Homologene: 1313
Wdr35
Name: WD repeat domain 35
Synonyms: 4930459M12Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74682
Homologene: 10814
Or8d2b
Name: olfactory receptor family 8 subfamily D member 2D
Synonyms: MOR171-8, Olfr926, GA_x6K02T2PVTD-32573036-32573962
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258811
VEGA: 9
HGNC: HGNC:8482
Homologene: 128215
Hkdc1
Name: hexokinase domain containing 1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216019
Homologene: 128937
Tmprss11g
Name: transmembrane protease, serine 11g
Synonyms: Desc4, 9930032O22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320454
Homologene: 82239
Slc31a1
Name: solute carrier family 31, member 1
Synonyms: 4930445G01Rik, Ctr1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20529
Homologene: 1399
Sp110
Name: Sp110 nuclear body protein
Synonyms: 5830484A20Rik, Ifi75, 5031415C07Rik, 52kDa, Ipr1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 109032
HGNC: HGNC:5401
Homologene: 82192
Cracd
Name: capping protein inhibiting regulator of actin
Synonyms: C530008M17Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320827
Homologene: 136278
Tmem14c
Name: transmembrane protein 14C
Synonyms: HSPC194, 1110021D01Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66154
VEGA: 13
Homologene: 8540
Asb1
Name: ankyrin repeat and SOCS box-containing 1
Synonyms: 1700054C17Rik, 1700029O08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 65247
Homologene: 9390
Pim3
Name: proviral integration site 3
Synonyms: Kid1, KID-1/kinase induced by depolarization
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223775
VEGA: 15
Homologene: 56955
Myl12a
Name: myosin, light chain 12A, regulatory, non-sarcomeric
Synonyms: NMDA receptor-interacting protein, brain specific myosin regulatory light chain, 2900073G15Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67268
Homologene: 68515
Dnase1l1
Name: deoxyribonuclease 1-like 1
Synonyms: Dnl1ll, G4.8, Dnase1ll, 2310005K03Rik
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 69537
HGNC: HGNC:2957
Homologene: 4896
Mgam2-ps
Name: maltase-glucoamylase 2, pseudogene
Synonyms: Gm7254
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 638904
Ighv16-1
Name: immunoglobulin heavy variable 16-1
Synonyms: Gm7005
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 629812
Gm20539
Name: predicted gene 20539
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Gm5860
Name: predicted gene 5860
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 545641
Krtap20-2
Name: keratin associated protein 20-2
Synonyms: 1190004K03Rik, Gm6371
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 622935
VEGA: 16
4930404I05Rik
Name: RIKEN cDNA 4930404I05 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67394
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 80,551,472 bp
  • G to C, chromosome 1 at 85,577,220 bp
  • A to G, chromosome 1 at 87,705,964 bp
  • A to G, chromosome 1 at 91,554,811 bp
  • A to C, chromosome 2 at 18,742,877 bp
  • A to G, chromosome 2 at 20,848,834 bp
  • A to T, chromosome 2 at 76,870,603 bp
  • G to A, chromosome 2 at 121,304,504 bp
  • C to T, chromosome 2 at 178,441,417 bp
  • T to A, chromosome 3 at 64,089,997 bp
  • T to C, chromosome 3 at 107,748,710 bp
  • T to C, chromosome 3 at 126,947,348 bp
  • CAGTT to CAGTTAGTT, chromosome 3 at 146,001,408 bp
  • A to T, chromosome 4 at 46,724,342 bp
  • T to C, chromosome 4 at 62,387,953 bp
  • T to A, chromosome 4 at 82,065,936 bp
  • T to A, chromosome 4 at 87,789,298 bp
  • C to A, chromosome 4 at 116,588,592 bp
  • T to C, chromosome 4 at 126,453,604 bp
  • T to A, chromosome 4 at 148,156,212 bp
  • G to C, chromosome 4 at 156,222,424 bp
  • G to A, chromosome 5 at 45,681,771 bp
  • A to G, chromosome 5 at 48,182,344 bp
  • A to G, chromosome 5 at 76,857,124 bp
  • G to A, chromosome 5 at 86,496,518 bp
  • T to C, chromosome 6 at 24,797,021 bp
  • A to G, chromosome 6 at 40,823,613 bp
  • A to T, chromosome 6 at 89,933,100 bp
  • T to A, chromosome 6 at 124,519,729 bp
  • C to T, chromosome 6 at 136,840,431 bp
  • G to A, chromosome 7 at 29,348,575 bp
  • C to T, chromosome 7 at 45,553,658 bp
  • T to A, chromosome 7 at 83,757,352 bp
  • A to T, chromosome 7 at 106,598,027 bp
  • A to G, chromosome 7 at 125,632,855 bp
  • T to C, chromosome 8 at 13,974,590 bp
  • T to C, chromosome 8 at 23,088,618 bp
  • T to A, chromosome 8 at 45,402,825 bp
  • C to T, chromosome 8 at 72,002,432 bp
  • A to G, chromosome 9 at 18,312,835 bp
  • T to C, chromosome 9 at 38,877,791 bp
  • T to A, chromosome 9 at 57,131,640 bp
  • A to G, chromosome 9 at 90,227,457 bp
  • C to A, chromosome 10 at 3,903,649 bp
  • T to C, chromosome 10 at 61,691,346 bp
  • T to C, chromosome 10 at 62,395,274 bp
  • T to C, chromosome 11 at 5,018,020 bp
  • T to C, chromosome 11 at 97,217,799 bp
  • T to C, chromosome 11 at 100,320,726 bp
  • T to A, chromosome 11 at 115,201,401 bp
  • T to C, chromosome 12 at 3,632,942 bp
  • C to T, chromosome 12 at 9,019,929 bp
  • C to T, chromosome 12 at 16,708,022 bp
  • G to A, chromosome 12 at 69,197,286 bp
  • T to A, chromosome 12 at 114,068,890 bp
  • C to T, chromosome 13 at 41,021,122 bp
  • G to T, chromosome 13 at 95,635,580 bp
  • A to G, chromosome 13 at 99,228,943 bp
  • T to A, chromosome 14 at 31,143,624 bp
  • G to A, chromosome 14 at 31,159,304 bp
  • C to T, chromosome 15 at 30,683,347 bp
  • T to A, chromosome 15 at 80,963,700 bp
  • T to C, chromosome 15 at 81,793,174 bp
  • T to C, chromosome 15 at 88,864,403 bp
  • T to C, chromosome 15 at 90,648,568 bp
  • G to T, chromosome 16 at 35,347,742 bp
  • G to T, chromosome 16 at 89,205,918 bp
  • A to T, chromosome 16 at 91,015,216 bp
  • C to A, chromosome 17 at 24,680,898 bp
  • T to C, chromosome 17 at 32,143,334 bp
  • T to A, chromosome 17 at 35,848,630 bp
  • T to A, chromosome 17 at 46,125,695 bp
  • T to C, chromosome 17 at 70,994,616 bp
  • A to T, chromosome 18 at 37,343,109 bp
  • A to T, chromosome 18 at 37,356,106 bp
  • C to T, chromosome X at 74,277,038 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5086 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042675-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.