Strain Name:
C57BL/6J-MtgxR5493Btlr/Mmmh
Stock Number:
043054-MU
Citation ID:
RRID:MMRRC_043054-MU
Other Names:
R5493 (G1), C57BL/6J-MtgxR5493Btlr
Major Collection:

Gene Information

Lypd2
Name: Ly6/Plaur domain containing 2
Synonyms: 0610005K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 68311
Homologene: 19022
Cdkn2d
Name: cyclin dependent kinase inhibitor 2D
Synonyms: p19, INK4d, p19INK4d, INK4d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12581
VEGA: 9
HGNC: HGNC:1790
Homologene: 36081
Il4i1
Name: interleukin 4 induced 1
Synonyms: H-46, H-4, H4, Fig1, Fig1-ps, H46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14204
Homologene: 22567
Bicral
Name: BRD4 interacting chromatin remodeling complex associated protein like
Synonyms: BC032203, Gltscr1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 210982
VEGA: 17
Homologene: 19366
Ppp1r9a
Name: protein phosphatase 1, regulatory subunit 9A
Synonyms: 4930518N04Rik, neurabin-I, A230094E16Rik, Neurabin I, NRB, 2810430P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 243725
Homologene: 14247
Slc25a12
Name: solute carrier family 25 (mitochondrial carrier, Aralar), member 12
Synonyms: B230107K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 78830
Homologene: 48235
Spag7
Name: sperm associated antigen 7
Synonyms: Fsa1l, FSA-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216873
Homologene: 3595
Dnajc21
Name: DnaJ heat shock protein family (Hsp40) member C21
Synonyms: 9930116P15Rik, 4930461P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 78244
Homologene: 6752
Pip5k1b
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
Synonyms: Pipk5b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18719
HGNC: HGNC:8995
Homologene: 100644
Kdm1a
Name: lysine (K)-specific demethylase 1A
Synonyms: Kdm1, LSD1, 1810043O07Rik, Aof2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 99982
Homologene: 32240
Cdk13
Name: cyclin-dependent kinase 13
Synonyms: Cdc2l5, 2310015O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 69562
VEGA: 13
HGNC: HGNC:1733
Homologene: 135707
Dctn1
Name: dynactin 1
Synonyms: Glued, p150, p150glued
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 13191
HGNC: HGNC:2711
Homologene: 3011
Asap1
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain1
Synonyms: Ddef1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 13196
HGNC: HGNC:2720
Homologene: 7684
Knl1
Name: kinetochore scaffold 1
Synonyms: 5730505K17Rik, 2310043D08Rik, Casc5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 76464
Homologene: 44890
Gtf3c1
Name: general transcription factor III C 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233863
HGNC: HGNC:4664
Homologene: 31040
Cse1l
Name: chromosome segregation 1-like (S. cerevisiae)
Synonyms: Capts, Cas, Xpo2, 2610100P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 110750
HGNC: HGNC:2431
Homologene: 1006
Coro7
Name: coronin 7
Synonyms: 0610011B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 78885
Homologene: 11573
Zfp26
Name: zinc finger protein 26
Synonyms: mkr-3, Zfp70, Zfp81-rs1, 5033428C05Rik, Zfp-26, KRAB15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22688
Homologene: 52318
Tenm2
Name: teneurin transmembrane protein 2
Synonyms: D3Bwg1534e, 2610040L17Rik, Ten-m2, Odz2, 9330187F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 23964
Homologene: 22672
Rtca
Name: RNA 3'-terminal phosphate cyclase
Synonyms: Rtcd1, 2310009A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66368
Homologene: 2766
Sp3
Name: trans-acting transcription factor 3
Synonyms: D130027J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20687
Homologene: 7952
Rbl2
Name: RB transcriptional corepressor like 2
Synonyms: retinoblastoma-like 2, Rb2, p130
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 19651
HGNC: HGNC:9894
Homologene: 4098
Gcnt2
Name: glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
Synonyms: IGnTC, IGnTB, IGnTA, 5330430K10Rik, IGnT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 14538
VEGA: 13
HGNC: HGNC:4204
Homologene: 41535
Eif2b3
Name: eukaryotic translation initiation factor 2B, subunit 3
Synonyms: 1190002P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 108067
HGNC: HGNC:3259
Homologene: 7005
Gmds
Name: GDP-mannose 4, 6-dehydratase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218138
HGNC: HGNC:4369
Homologene: 75968
Zfp459
Name: zinc finger protein 459
Synonyms: Rslcan-14, 9930025G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 328274
Pgap3
Name: post-GPI attachment to proteins 3
Synonyms: CAB2, Perld1, D430035D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 320655
Homologene: 5484
Serpind1
Name: serine (or cysteine) peptidase inhibitor, clade D, member 1
Synonyms: Hcf2, heparin cofactor II, HC II, HCII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 15160
HGNC: HGNC:4838
Homologene: 36018
Fance
Name: Fanconi anemia, complementation group E
Synonyms: 2810451D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 72775
HGNC: HGNC:3586
Homologene: 11066
Ksr2
Name: kinase suppressor of ras 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 333050
Homologene: 45469
Zbtb5
Name: zinc finger and BTB domain containing 5
Synonyms: 9430083K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230119
Homologene: 8913
Agpat3
Name: 1-acylglycerol-3-phosphate O-acyltransferase 3
Synonyms: LPAAT3, D10Jhu12e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 28169
HGNC: HGNC:326
Homologene: 10591
Il12rb1
Name: interleukin 12 receptor, beta 1
Synonyms: CD212, IL-12R[b]
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16161
HGNC: HGNC:5971
Homologene: 4042
Cd180
Name: CD180 antigen
Synonyms: RP105, Ly78
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17079
HGNC: HGNC:6726
Homologene: 4077
Zfp942
Name: zinc finger protein 942
Synonyms: 3110048L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 73233
Homologene: 133237
Gm4847
Name: predicted gene 4847
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226604
Homologene: 101040
Tbx15
Name: T-box 15
Synonyms: Tbx14, de, Tbx8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 21384
Homologene: 7967
Kcns1
Name: K+ voltage-gated channel, subfamily S, 1
Synonyms: Kv9.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16538
HGNC: HGNC:6300
Homologene: 20517
Clrn1
Name: clarin 1
Synonyms: clarin-1, A130002D11Rik, USH3, Ush3a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229320
Homologene: 17738
D130043K22Rik
Name: RIKEN cDNA D130043K22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 210108
Homologene: 8878
Exoc7
Name: exocyst complex component 7
Synonyms: 70kDa, sec70, Exo70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 53413
Homologene: 41019
Rin2
Name: Ras and Rab interactor 2
Synonyms: 4632403N06Rik, 2010003K16Rik, RASSF4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74030
Homologene: 32430
Man1a
Name: mannosidase 1, alpha
Synonyms: mannosyl-oligosaccharide alpha-1,2-mannosidase, PCR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 17155
HGNC: HGNC:6821
Homologene: 4316
Duox2
Name: dual oxidase 2
Synonyms: A430065P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 214593
Homologene: 9689
Olfr70
Name: olfactory receptor 70
Synonyms: GA_x6K02T2N78B-16239704-16240654, mOR6, MOR262-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56014
Homologene: 10459
Qrich2
Name: glutamine rich 2
Synonyms: LOC217341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217341
Homologene: 12951
Ppip5k1
Name: diphosphoinositol pentakisphosphate kinase 1
Synonyms: B430315C20Rik, Hisppd2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 327655
Homologene: 49395
Gm8994
Name: predicted gene 8994
Synonyms: B020013A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 668137
Vmn1r39
Name: vomeronasal 1 receptor 39
Synonyms: Gm5993
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 546903
Homologene: 110800
Stk25
Name: serine/threonine kinase 25 (yeast)
Synonyms: Ste20-like, SOK-1, 1500019J11Rik, Ysk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 59041
Homologene: 48428
Olfr561
Name: olfactory receptor 561
Synonyms: MOR14-2, GA_x6K02T2PBJ9-5491151-5492095
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259096
Homologene: 133029
Aldh18a1
Name: aldehyde dehydrogenase 18 family, member A1
Synonyms: 2810433K04Rik, Pycs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 56454
HGNC: HGNC:9722
Homologene: 2142
Ipo4
Name: importin 4
Synonyms: 8430408O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 75751
Homologene: 5835
Olfr504
Name: olfactory receptor 504
Synonyms: GA_x6K02T2PBJ9-10895499-10894543, MOR40-15, MOR40-7P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258163
Homologene: 17189
Shox2
Name: short stature homeobox 2
Synonyms: Prx3, 6330543G17Rik, Og12x
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20429
Homologene: 68535
Klk14
Name: kallikrein related-peptidase 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 317653
HGNC: HGNC:6362
Homologene: 69348
A830018L16Rik
Name: RIKEN cDNA A830018L16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 320492
Homologene: 14194
Gm20730
Name: predicted gene, 20730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
Hk3
Name: hexokinase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 212032
HGNC: HGNC:4925
Homologene: 55633
Zfp764
Name: zinc finger protein 764
Synonyms: 8030466O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233893
Homologene: 62158
Olfr1364
Name: olfactory receptor 1364
Synonyms: MOR256-13, GA_x6K02T2QHY8-11663090-11664010
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 258533
Homologene: 64885
Utp11
Name: UTP11 small subunit processome component
Synonyms: Utp11l, 2700082D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 67205
Homologene: 6349
Cyp2a12
Name: cytochrome P450, family 2, subfamily a, polypeptide 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13085
Homologene: 69128
Ifnlr1
Name: interferon lambda receptor 1
Synonyms: Il28ra, CRF2-12, IFNLR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242700
Homologene: 52086
Olfr533
Name: olfactory receptor 533
Synonyms: MOR252-3P, GA_x6K02T2PBJ9-42615403-42616365
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258056
Homologene: 128384
Tox2
Name: TOX high mobility group box family member 2
Synonyms: LOC269389, RxHMG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269389
Homologene: 13155
Zfp703
Name: zinc finger protein 703
Synonyms: Zeppo1, Csmn1, End2, 1110032O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 353310
Homologene: 81391
Aloxe3
Name: arachidonate lipoxygenase 3
Synonyms: e-LOX-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 23801
Homologene: 8013
2510009E07Rik
Name: RIKEN cDNA 2510009E07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 72190
VEGA: 16
Homologene: 78167
Kcnmb2
Name: potassium large conductance calcium-activated channel, subfamily M, beta member 2
Synonyms: 3110031N04Rik, 2700049B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 72413
HGNC: HGNC:6286
Homologene: 4257
Rbpjl
Name: recombination signal binding protein for immunoglobulin kappa J region-like
Synonyms: RBP-L, Rbpsuhl, RBP-J kappa-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19668
Homologene: 7512
Fbxw25
Name: F-box and WD-40 domain protein 25
Synonyms: E330001B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 546160
Pcdha2
Name: protocadherin alpha 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 353234
HGNC: HGNC:8668
Homologene: 135719
Gm26896
Name: predicted gene, 26896
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 11,545,207 bp
  • A to T, chromosome 1 at 93,635,309 bp
  • T to A, chromosome 1 at 166,630,321 bp
  • C to T, chromosome 2 at 71,282,566 bp
  • T to A, chromosome 2 at 72,938,122 bp
  • T to A, chromosome 2 at 119,068,730 bp
  • T to A, chromosome 2 at 121,336,772 bp
  • T to C, chromosome 2 at 122,281,496 bp
  • A to G, chromosome 2 at 145,860,709 bp
  • C to A, chromosome 2 at 163,204,729 bp
  • G to A, chromosome 2 at 164,167,979 bp
  • GCC to GC, chromosome 2 at 164,414,410 bp
  • A to G, chromosome 2 at 166,941,190 bp
  • A to G, chromosome 3 at 32,198,142 bp
  • A to G, chromosome 3 at 58,846,416 bp
  • C to G, chromosome 3 at 66,981,463 bp
  • G to A, chromosome 3 at 99,352,564 bp
  • C to T, chromosome 3 at 116,499,631 bp
  • A to G, chromosome 4 at 43,696,225 bp
  • A to T, chromosome 4 at 44,993,941 bp
  • A to G, chromosome 4 at 117,086,722 bp
  • C to T, chromosome 4 at 124,679,759 bp
  • G to A, chromosome 4 at 135,705,566 bp
  • ACC to AC, chromosome 4 at 136,557,421 bp
  • G to T, chromosome 5 at 117,708,110 bp
  • A to G, chromosome 6 at 5,159,702 bp
  • A to T, chromosome 6 at 43,081,812 bp
  • A to G, chromosome 6 at 66,804,770 bp
  • G to T, chromosome 6 at 83,182,564 bp
  • C to G, chromosome 6 at 136,329,557 bp
  • T to C, chromosome 7 at 27,029,125 bp
  • G to A, chromosome 7 at 43,692,077 bp
  • G to T, chromosome 7 at 44,840,053 bp
  • A to T, chromosome 7 at 102,775,108 bp
  • T to C, chromosome 7 at 108,565,567 bp
  • T to C, chromosome 7 at 125,670,544 bp
  • A to G, chromosome 7 at 127,404,933 bp
  • A to T, chromosome 7 at 140,466,807 bp
  • C to T, chromosome 8 at 26,979,205 bp
  • C to A, chromosome 8 at 70,809,839 bp
  • C to T, chromosome 8 at 91,115,819 bp
  • T to C, chromosome 9 at 20,444,319 bp
  • T to C, chromosome 9 at 21,289,007 bp
  • T to C, chromosome 9 at 109,652,916 bp
  • A to G, chromosome 10 at 54,074,480 bp
  • A to G, chromosome 10 at 78,284,235 bp
  • A to T, chromosome 10 at 81,609,131 bp
  • T to C, chromosome 11 at 36,864,676 bp
  • A to T, chromosome 11 at 69,128,617 bp
  • T to A, chromosome 11 at 70,669,233 bp
  • G to C, chromosome 11 at 98,390,714 bp
  • G to A, chromosome 11 at 116,291,222 bp
  • A to C, chromosome 11 at 116,445,948 bp
  • T to C, chromosome 13 at 17,803,562 bp
  • A to T, chromosome 13 at 21,573,872 bp
  • A to G, chromosome 13 at 24,863,603 bp
  • A to T, chromosome 13 at 31,940,505 bp
  • A to G, chromosome 13 at 40,953,600 bp
  • A to G, chromosome 13 at 55,011,171 bp
  • C to A, chromosome 13 at 67,408,379 bp
  • T to A, chromosome 13 at 102,706,141 bp
  • T to C, chromosome 14 at 55,630,870 bp
  • T to A, chromosome 15 at 10,461,909 bp
  • A to G, chromosome 15 at 64,130,151 bp
  • A to G, chromosome 15 at 64,191,595 bp
  • T to C, chromosome 15 at 74,734,278 bp
  • A to G, chromosome 16 at 4,632,487 bp
  • A to T, chromosome 16 at 17,340,038 bp
  • A to G, chromosome 16 at 21,653,243 bp
  • T to C, chromosome 17 at 21,933,004 bp
  • G to A, chromosome 17 at 28,320,790 bp
  • C to A, chromosome 17 at 46,801,694 bp
  • C to A, chromosome 18 at 36,939,509 bp
  • T to C, chromosome 19 at 24,439,075 bp
  • C to T, chromosome 19 at 40,551,290 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5493 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043054-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.