Strain Name:
C57BL/6J-MtgxR5625Btlr/Mmmh
Stock Number:
043164-MU
Citation ID:
RRID:MMRRC_043164-MU
Other Names:
R5625 (G1), C57BL/6J-MtgxR5625Btlr
Major Collection:

Gene Information

Lrrn1
Name: leucine rich repeat protein 1, neuronal
Synonyms: NLRR-1, 2810047E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16979
Homologene: 32036
Nudt3
Name: nudix (nucleotide diphosphate linked moiety X)-type motif 3
Synonyms: diphosphoinositol polyphosphate phosphohydrolase, Dipp, 1110011B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 56409
HGNC: HGNC:8050
Homologene: 31400
Srsf11
Name: serine and arginine-rich splicing factor 11
Synonyms: 0610009J05Rik, 2610019N13Rik, Sfrs11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 69207
Homologene: 36164
Ppp6c
Name: protein phosphatase 6, catalytic subunit
Synonyms: 2310003C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67857
HGNC: HGNC:9323
Homologene: 68273
Wnk1
Name: WNK lysine deficient protein kinase 1
Synonyms: EG406236, 6430573H23Rik, Hsn2, Prkwnk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232341
Homologene: 14253
Exo1
Name: exonuclease 1
Synonyms: Msa, 5730442G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 26909
HGNC: HGNC:3511
Homologene: 31352
Sec23ip
Name: Sec23 interacting protein
Synonyms: p125, D7Ertd373e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 207352
Homologene: 38288
Angel2
Name: angel homolog 2
Synonyms: D1Ertd654e, 5730410O10Rik, 2610307I21Rik, D1Ertd396e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 52477
Homologene: 16932
Bmp1
Name: bone morphogenetic protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 12153
VEGA: 14
HGNC: HGNC:1067
Homologene: 55955
Hapln3
Name: hyaluronan and proteoglycan link protein 3
Synonyms: 4930554N11Rik, Lpr3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67666
Homologene: 18654
Pi4kb
Name: phosphatidylinositol 4-kinase beta
Synonyms: ESTM41, Pik4cb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 107650
HGNC: HGNC:8984
Homologene: 6741
Usp8
Name: ubiquitin specific peptidase 8
Synonyms: Ubpy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 84092
Homologene: 3782
Tubgcp3
Name: tubulin, gamma complex associated protein 3
Synonyms: Spc98p, GCP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 259279
Homologene: 4609
Szt2
Name: SZT2 subunit of KICSTOR complex
Synonyms: seaizure threshold 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230676
Homologene: 49413
Piezo1
Name: piezo-type mechanosensitive ion channel component 1
Synonyms: Piezo1, Fam38a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234839
Homologene: 124356
Tmem50a
Name: transmembrane protein 50A
Synonyms: 3200001F09Rik, CAM, Smp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 71817
Homologene: 4469
Pdgfra
Name: platelet derived growth factor receptor, alpha polypeptide
Synonyms: Pdgfr-2, CD140a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18595
HGNC: HGNC:8803
Homologene: 31361
Cep295
Name: centrosomal protein 295
Synonyms: 5830418K08Rik, LOC382128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319675
Homologene: 27936
Rhbdf2
Name: rhomboid 5 homolog 2
Synonyms: iRhom2, 4732465I17Rik, Rhbdl6, cub
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217344
Homologene: 11612
Prkg1
Name: protein kinase, cGMP-dependent, type I
Synonyms: Prkgr1b, Prkg1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 19091
HGNC: HGNC:9414
Homologene: 55964
Col13a1
Name: collagen, type XIII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12817
HGNC: HGNC:2190
Homologene: 22421
Insc
Name: INSC spindle orientation adaptor protein
Synonyms: 3830422K02Rik, Inscuteable
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233752
Homologene: 78662
Mycbpap
Name: MYCBP associated protein
Synonyms: AMAP-1, 4932408B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 104601
Homologene: 49982
Uggt2
Name: UDP-glucose glycoprotein glucosyltransferase 2
Synonyms: A230065J02Rik, 3110027P15Rik, Ugcgl2, 3110001A05Rik, 1810064L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66435
Homologene: 56875
Otop1
Name: otopetrin 1
Synonyms: A530025J20Rik, tlt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 21906
Homologene: 35244
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: syne-2, D12Ertd777e, Cpfl8, diminished cone electroretinogram, dice, 6820443O06Rik, Nesp2g, nesprin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319565
Homologene: 56700
Wdr93
Name: WD repeat domain 93
Synonyms: EG626359
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 626359
Homologene: 56878
Abcg4
Name: ATP binding cassette subfamily G member 4
Synonyms: 6430517O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 192663
Homologene: 75179
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329628
Homologene: 14377
Sptbn5
Name: spectrin beta, non-erythrocytic 5
Synonyms: Spnb5, EG640524
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 640524
Homologene: 41150
Cfap44
Name: cilia and flagella associated protein 44
Synonyms: 6330444M21Rik, D16Ertd642e, Wdr52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 212517
Homologene: 75085
Ampd3
Name: adenosine monophosphate deaminase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11717
HGNC: HGNC:470
Homologene: 408
D430041D05Rik
Name: RIKEN cDNA D430041D05 gene
Synonyms: G2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241589
Homologene: 115928
Olfr955
Name: olfactory receptor 955
Synonyms: MOR171-50, GA_x6K02T2PVTD-33167297-33166353, MOR171-34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258242
VEGA: 9
Homologene: 133698
Tmem62
Name: transmembrane protein 62
Synonyms: B830009D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 96957
Homologene: 11801
Farp2
Name: FERM, RhoGEF and pleckstrin domain protein 2
Synonyms: D030026M03Rik, Fir
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227377
Homologene: 8877
Tnxb
Name: tenascin XB
Synonyms: Tnx, TN-MHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 81877
Homologene: 49589
Zfp575
Name: zinc finger protein 575
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101544
Homologene: 45485
Vmn2r59
Name: vomeronasal 2, receptor 59
Synonyms: EG628444
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 628444
Homologene: 129683
Nrg3
Name: neuregulin 3
Synonyms: ska
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18183
HGNC: HGNC:7999
Homologene: 32051
Zfp616
Name: zinc finger protein 616
Synonyms: Gm12330
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327963
Homologene: 88945
Clip1
Name: CAP-GLY domain containing linker protein 1
Synonyms: Clip 170, Rsn, 1110007I12Rik, restin, 4631429H07Rik, CLIP-170, Clip50, cytoplasmic linker protein 50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56430
Homologene: 74455
Ccdc157
Name: coiled-coil domain containing 157
Synonyms: 4930562D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216516
Homologene: 72271
Ptpru
Name: protein tyrosine phosphatase, receptor type, U
Synonyms: RPTPlambda, Ptprl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Vmn1r19
Name: vomeronasal 1 receptor 19
Synonyms: V1rc27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171200
Homologene: 134034
Gbp2b
Name: guanylate binding protein 2b
Synonyms: Gbp1, Gbp-1, Mag-1, Mpa1, Mpa-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14468
HGNC: HGNC:4184
Homologene: 137233
Pcare
Name: photoreceptor cilium actin regulator
Synonyms: BC027072
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 225004
VEGA: 17
Homologene: 19792
Rasl10b
Name: RAS-like, family 10, member B
Synonyms: B230331P10Rik, VTS58635
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 276952
Homologene: 14108
Det1
Name: de-etiolated homolog 1 (Arabidopsis)
Synonyms: 2610034H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76375
Homologene: 9952
Cyp3a44
Name: cytochrome P450, family 3, subfamily a, polypeptide 44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 337924
HGNC: HGNC:2638
Homologene: 133568
Brsk1
Name: BR serine/threonine kinase 1
Synonyms: SAD-B, LOC381979
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381979
Homologene: 57169
Ifi213
Name: interferon activated gene 213
Synonyms: Pyr-A, E030037K03Rik, Pydc4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 623121
HGNC: HGNC:5395
Homologene: 115929
Cxcr2
Name: chemokine (C-X-C motif) receptor 2
Synonyms: Il8rb, IL8RA, CD128, IL-8rb, Cmkar2, Gpcr16, IL-8Rh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12765
HGNC: HGNC:6027
Homologene: 10439
Tex46
Name: testis expressed 46
Synonyms: 4930549C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67663
Homologene: 136495
Vmn2r129
Name: vomeronasal 2, receptor 129
Synonyms: V2r8, Vmn2r-ps159, Vmn2r-ps160, V2r9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22314
Gm1988
Name: predicted gene 1988
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100038967
Homologene: 80005
D630002J18Rik
Name: RIKEN cDNA D630002J18 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Gm2366
Name: predicted gene 2366
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Gm10941
Name: predicted gene 10941
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100169878
VEGA: 10
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 74,158,832 bp
  • T to G, chromosome 1 at 93,528,748 bp
  • A to G, chromosome 1 at 173,569,063 bp
  • G to T, chromosome 1 at 175,893,814 bp
  • T to C, chromosome 1 at 190,937,634 bp
  • A to G, chromosome 2 at 39,197,441 bp
  • A to T, chromosome 2 at 52,177,535 bp
  • T to A, chromosome 2 at 104,201,153 bp
  • A to T, chromosome 2 at 120,079,792 bp
  • G to T, chromosome 2 at 120,990,393 bp
  • C to T, chromosome 2 at 126,742,277 bp
  • A to T, chromosome 3 at 38,888,934 bp
  • A to G, chromosome 3 at 94,984,677 bp
  • T to A, chromosome 3 at 142,599,045 bp
  • C to T, chromosome 3 at 152,165,904 bp
  • C to T, chromosome 3 at 158,023,344 bp
  • A to G, chromosome 4 at 118,373,217 bp
  • T to C, chromosome 4 at 131,803,380 bp
  • AACCA to AA, chromosome 4 at 134,898,467 bp
  • T to C, chromosome 4 at 136,610,614 bp
  • A to T, chromosome 4 at 156,334,210 bp
  • A to T, chromosome 5 at 38,302,761 bp
  • G to A, chromosome 5 at 75,189,337 bp
  • G to A, chromosome 5 at 123,580,026 bp
  • C to T, chromosome 5 at 145,779,566 bp
  • T to C, chromosome 6 at 57,405,296 bp
  • T to A, chromosome 6 at 107,567,354 bp
  • A to T, chromosome 6 at 119,926,460 bp
  • A to G, chromosome 7 at 4,706,400 bp
  • G to A, chromosome 7 at 24,585,652 bp
  • A to T, chromosome 7 at 39,173,805 bp
  • A to T, chromosome 7 at 42,046,460 bp
  • G to A, chromosome 7 at 78,834,170 bp
  • G to T, chromosome 7 at 79,117,258 bp
  • A to G, chromosome 7 at 79,771,018 bp
  • A to C, chromosome 7 at 110,802,523 bp
  • A to G, chromosome 7 at 114,829,067 bp
  • G to T, chromosome 7 at 128,744,983 bp
  • T to C, chromosome 8 at 12,624,888 bp
  • G to A, chromosome 8 at 45,017,915 bp
  • T to C, chromosome 8 at 122,482,960 bp
  • A to C, chromosome 9 at 15,340,891 bp
  • T to A, chromosome 9 at 39,469,803 bp
  • T to G, chromosome 9 at 44,278,036 bp
  • C to T, chromosome 10 at 61,843,609 bp
  • G to T, chromosome 10 at 77,258,836 bp
  • A to T, chromosome 11 at 4,151,888 bp
  • A to G, chromosome 11 at 74,071,707 bp
  • G to T, chromosome 11 at 83,418,814 bp
  • T to C, chromosome 11 at 94,505,693 bp
  • G to A, chromosome 11 at 116,605,377 bp
  • T to C, chromosome 12 at 76,095,112 bp
  • A to T, chromosome 14 at 38,370,993 bp
  • G to T, chromosome 14 at 70,486,166 bp
  • A to G, chromosome 14 at 119,077,724 bp
  • G to T, chromosome 16 at 44,460,347 bp
  • A to G, chromosome 17 at 27,583,228 bp
  • G to A, chromosome 17 at 34,685,211 bp
  • T to A, chromosome 17 at 71,751,326 bp
  • C to T, chromosome 19 at 31,764,762 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5625 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043164-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.