Strain Name:
C57BL/6J-MtgxR5148Btlr
Stock Number:
043262-MU
Citation ID:
RRID:MMRRC_043262-MU
Other Names:
R5148 (G1)
Major Collection:

Gene Information

Ank2
Name: ankyrin 2, brain
Synonyms: ankyrin B, Ank-2, Ankyrin-2, Ankyrin-B, Gm4392
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Cacna1h
Name: calcium channel, voltage-dependent, T type, alpha 1H subunit
Synonyms: Cav3.2, alpha13.2, T-type Cav3.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 58226
HGNC: HGNC:1395
Homologene: 56913
Olr1
Name: oxidized low density lipoprotein (lectin-like) receptor 1
Synonyms: LOX-1, Scare1, SR-EI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 108078
HGNC: HGNC:8133
Homologene: 1910
Slc12a8
Name: solute carrier family 12 (potassium/chloride transporters), member 8
Synonyms: E330020C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 171286
Homologene: 11628
Phf14
Name: PHD finger protein 14
Synonyms: 1110001C23Rik, 4932409F11Rik, 5730446A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 75725
Homologene: 8775
Lin9
Name: lin-9 DREAM MuvB core complex component
Synonyms: 2700022J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72568
Homologene: 35252
Pafah1b1
Name: platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
Synonyms: Lis1, LIS-1, lissencephaly-1 protein, Mdsh, Pafaha, PAF-AH 45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18472
HGNC: HGNC:8574
Homologene: 371
Phldb1
Name: pleckstrin homology like domain, family B, member 1
Synonyms: LL5A, D330037A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102693
Homologene: 15903
Atf7
Name: activating transcription factor 7
Synonyms: C130020M04Rik, 1110012F10Rik, 9430065F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223922
HGNC: HGNC:792
Homologene: 4994
Zfp981
Name: zinc finger protein 981
Synonyms: Gm13247
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100041433
Homologene: 133076
Map3k14
Name: mitogen-activated protein kinase kinase kinase 14
Synonyms: Nik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 53859
HGNC: HGNC:6853
Homologene: 2940
Il17rc
Name: interleukin 17 receptor C
Synonyms: IL17-RL, Il17rl, 1110025H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171095
Homologene: 15894
Lrrc40
Name: leucine rich repeat containing 40
Synonyms: 2610040E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67144
Homologene: 9825
Morc2a
Name: microrchidia 2A
Synonyms: 8430403M08Rik, Zcwcc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74522
Homologene: 8966
Wrnip1
Name: Werner helicase interacting protein 1
Synonyms: WHIP, 4833444L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 78903
Homologene: 10592
Cngb1
Name: cyclic nucleotide gated channel beta 1
Synonyms: Cngb1, Cngb1b, BC016201
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 333329
HGNC: HGNC:2151
Homologene: 136420
Ptpn13
Name: protein tyrosine phosphatase, non-receptor type 13
Synonyms: PTP-BL, Ptpri, PTPL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19249
HGNC: HGNC:9646
Homologene: 7909
Egfem1
Name: EGF-like and EMI domain containing 1
Synonyms: 6130401L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75740
Homologene: 135950
Ralgps1
Name: Ral GEF with PH domain and SH3 binding motif 1
Synonyms: RALGPS1A, RALGEF2, 5830418G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241308
Homologene: 65163
Vmn2r6
Name: vomeronasal 2, receptor 6
Synonyms: EG620718, EG667069
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 667069
Homologene: 129754
Pnldc1
Name: poly(A)-specific ribonuclease (PARN)-like domain containing 1
Synonyms: LOC240023
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240023
VEGA: 17
Homologene: 15054
Vmn2r3
Name: vomeronasal 2, receptor 3
Synonyms: EG637004
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 637004
Dbt
Name: dihydrolipoamide branched chain transacylase E2
Synonyms: BCKAD E2, D3Wsu60e, dihydrolipoyl transacylase, dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 13171
HGNC: HGNC:2698
Homologene: 1444
Nlrc5
Name: NLR family, CARD domain containing 5
Synonyms: AI451557
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 434341
Homologene: 88935
T
Name: brachyury, T-box transcription factor T
Synonyms: T1, Bra, Tbxt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20997
Homologene: 2393
Gm12790
Name: predicted gene 12790
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Trim47
Name: tripartite motif-containing 47
Synonyms: 2210023F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217333
Homologene: 14128
Sdr42e1
Name: short chain dehydrogenase/reductase family 42E, member 1
Synonyms: 4632417N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74032
Homologene: 23654
Serpina11
Name: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
Synonyms: LOC380780
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 380780
Homologene: 28490
Gss
Name: glutathione synthetase
Synonyms: GS-A/GS-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14854
HGNC: HGNC:4624
Homologene: 148
Olfr1162
Name: olfactory receptor 1162
Synonyms: GA_x6K02T2Q125-49542541-49541597, MOR174-14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258105
Homologene: 79476
Olfr1487
Name: olfactory receptor 1487
Synonyms: GA_x6K02T2RE5P-3951719-3952666, MOR202-18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258629
Homologene: 110492
Gpcpd1
Name: glycerophosphocholine phosphodiesterase 1
Synonyms: 2310032D16Rik, 2310004G06Rik, Prei4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74182
Homologene: 10478
Olfr894
Name: olfactory receptor 894
Synonyms: GA_x6K02T2PVTD-31898993-31899934, MOR170-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258868
Ly6f
Name: lymphocyte antigen 6 complex, locus F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17071
Homologene: 113718
Snrpd1
Name: small nuclear ribonucleoprotein D1
Synonyms: SMD1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 20641
VEGA: 18
Homologene: 107532
Pira2
Name: paired-Ig-like receptor A2
Synonyms: 6M23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18725
HGNC: HGNC:6607
Homologene: 134028
Tmem156
Name: transmembrane protein 156
Synonyms: LOC243025
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243025
Homologene: 49811
Lhfpl5
Name: lipoma HMGIC fusion partner-like 5
Synonyms: 9330179O15Rik, Tmhs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 328789
Homologene: 18794
Prss29
Name: protease, serine 29
Synonyms: mISP-2, Isp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 114662
VEGA: 17
Homologene: 70877
Ssbp1
Name: single-stranded DNA binding protein 1
Synonyms: 2810480P10Rik, mtDBP, G630031O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 381760
Homologene: 74462
Gm5444
Name: predicted gene 5444
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Malrd1
Name: MAM and LDL receptor class A domain containing 1
Synonyms: Gm13318, Gm13364, Diet1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 102635496
Homologene: 136214
Cntf
Name: ciliary neurotrophic factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 12803
HGNC: HGNC:2169
Homologene: 8288
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 180,669,198 bp
  • A to G, chromosome 2 at 16,142,226 bp
  • A to C, chromosome 2 at 33,158,987 bp
  • G to A, chromosome 2 at 88,050,393 bp
  • A to T, chromosome 2 at 132,534,190 bp
  • G to T, chromosome 2 at 155,573,109 bp
  • G to A, chromosome 3 at 29,457,823 bp
  • G to T, chromosome 3 at 64,278,826 bp
  • A to C, chromosome 3 at 64,556,594 bp
  • T to C, chromosome 3 at 116,528,244 bp
  • A to T, chromosome 3 at 127,025,636 bp
  • T to G, chromosome 3 at 158,054,569 bp
  • C to T, chromosome 4 at 101,968,071 bp
  • A to T, chromosome 4 at 146,536,900 bp
  • T to C, chromosome 5 at 65,073,768 bp
  • C to T, chromosome 5 at 103,492,232 bp
  • A to T, chromosome 6 at 11,961,642 bp
  • T to C, chromosome 6 at 40,477,949 bp
  • G to T, chromosome 6 at 113,482,997 bp
  • G to T, chromosome 6 at 129,493,609 bp
  • T to G, chromosome 7 at 3,844,593 bp
  • G to T, chromosome 8 at 94,476,693 bp
  • A to G, chromosome 8 at 95,265,983 bp
  • T to A, chromosome 8 at 117,663,603 bp
  • T to C, chromosome 9 at 38,219,021 bp
  • A to G, chromosome 9 at 44,704,158 bp
  • T to C, chromosome 11 at 3,689,084 bp
  • A to T, chromosome 11 at 74,684,452 bp
  • T to C, chromosome 11 at 103,239,332 bp
  • G to T, chromosome 11 at 116,107,852 bp
  • A to T, chromosome 12 at 103,986,244 bp
  • C to T, chromosome 13 at 4,834,315 bp
  • G to T, chromosome 13 at 32,806,856 bp
  • A to G, chromosome 15 at 75,271,797 bp
  • A to G, chromosome 15 at 102,547,173 bp
  • G to A, chromosome 16 at 33,624,918 bp
  • A to G, chromosome 17 at 8,436,205 bp
  • T to C, chromosome 17 at 12,892,789 bp
  • T to C, chromosome 17 at 25,320,907 bp
  • C to A, chromosome 17 at 25,387,545 bp
  • T to A, chromosome 17 at 28,579,968 bp
  • T to A, chromosome 18 at 10,626,892 bp
  • T to C, chromosome 19 at 12,764,004 bp
  • C to A, chromosome 19 at 13,619,510 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5148 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043262-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.