Strain Name:
C57BL/6J-MtgxR5956Btlr
Stock Number:
044144-MU
Citation ID:
RRID:MMRRC_044144-MU
Other Names:
R5956 (G1)
Major Collection:

Gene Information

Ank2
Name: ankyrin 2, brain
Synonyms: Ankyrin-2, Gm4392, Ank-2, ankyrin B, Ankyrin-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 109676
HGNC: HGNC:493
Nsd1
Name: nuclear receptor-binding SET-domain protein 1
Synonyms: KMT3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18193
VEGA: 13
Homologene: 32543
Taf8
Name: TATA-box binding protein associated factor 8
Synonyms: Tbn, Taf8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 63856
VEGA: 17
Homologene: 11094
Zfp568
Name: zinc finger protein 568
Synonyms: LOC381866, chato
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243905
Homologene: 136307
Usp30
Name: ubiquitin specific peptidase 30
Synonyms: 6330590F17Rik, D5Ertd483e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100756
Homologene: 32789
Ube3c
Name: ubiquitin protein ligase E3C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100763
Homologene: 8783
Papola
Name: poly (A) polymerase alpha
Synonyms: Plap, PapIII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 18789
Homologene: 23389
Ddx54
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
Synonyms: 2410015A15Rik, APR-5, DP97
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71990
Homologene: 5590
Nomo1
Name: nodal modulator 1
Synonyms: D7Ertd156e, Nomo, PM5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 211548
Homologene: 13810
Ube3a
Name: ubiquitin protein ligase E3A
Synonyms: 5830462N02Rik, A130086L21Rik, E6-AP ubiquitin protein ligase, Hpve6a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22215
Homologene: 7988
Exoc2
Name: exocyst complex component 2
Synonyms: Sec5l1, 2410030I24Rik, Sec5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 66482
Homologene: 10122
Trrap
Name: transformation/transcription domain-associated protein
Synonyms: transactivation/transformation-domain associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100683
Homologene: 39246
Myo1b
Name: myosin IB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 17912
HGNC: HGNC:7596
Homologene: 7856
Cnot1
Name: CCR4-NOT transcription complex, subunit 1
Synonyms: 6030411K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234594
HGNC: HGNC:7877
Homologene: 9453
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: IP3R1, opt, Pcp1, wblo, Pcp-1, Ip3r, P400, InsP3R type I, Itpr-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Dhx16
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 16
Synonyms: Ddx16, DBP2, 2410006N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 69192
HGNC: HGNC:2739
Homologene: 2658
Grm4
Name: glutamate receptor, metabotropic 4
Synonyms: Gprc1d, mGluR4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 268934
HGNC: HGNC:4596
Homologene: 20230
Scn10a
Name: sodium channel, voltage-gated, type X, alpha
Synonyms: Nav1.8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20264
VEGA: 9
Homologene: 21300
Pole
Name: polymerase (DNA directed), epsilon
Synonyms: pol-epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18973
HGNC: HGNC:9177
Homologene: 4539
Crim1
Name: cysteine rich transmembrane BMP regulator 1 (chordin like)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 50766
VEGA: 17
HGNC: HGNC:2359
Homologene: 9510
Gbx2
Name: gastrulation brain homeobox 2
Synonyms: Stra7, Gbx-2, MMoxA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14472
HGNC: HGNC:4186
Homologene: 1138
Irx4
Name: Iroquois homeobox 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 50916
HGNC: HGNC:6129
Homologene: 9485
Sptb
Name: spectrin beta, erythrocytic
Synonyms: spectrin R, brain erythroid spectrin (235E), LOC383567, Spnb-1, Spnb1, D330027P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 20741
Homologene: 295
2700049A03Rik
Name: RIKEN cDNA 2700049A03 gene
Synonyms: talpid3, Ta3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 76967
Homologene: 8839
Efl1
Name: elongation factor like GTPase 1
Synonyms: Eftud1, 4932434J20Rik, 6030468D11Rik, D7Ertd791e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 101592
Homologene: 11599
Mctp2
Name: multiple C2 domains, transmembrane 2
Synonyms: LOC244049
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244049
Homologene: 69254
Siglece
Name: sialic acid binding Ig-like lectin E
Synonyms: Siglec5, mSiglec-E, Siglecl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 83382
Homologene: 130669
Amy1
Name: amylase 1, salivary
Synonyms: Amy-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 11722
Homologene: 20179
Epha5
Name: Eph receptor A5
Synonyms: Hek7, Rek7, Cek7, bsk, Els1, Ehk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 13839
HGNC: HGNC:3389
Homologene: 55824
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Wdr95
Name: WD40 repeat domain 95
Synonyms: 4930434E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 381693
Homologene: 124480
Unc80
Name: unc-80, NALCN activator
Synonyms: C030018G13Rik, C230061B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329178
Homologene: 122243
Gm1966
Name: predicted gene 1966
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434223
Homologene: 32708
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239420
Homologene: 65982
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC5, MUC9, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Cep126
Name: centrosomal protein 126
Synonyms: AK129341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 234915
VEGA: 9
Homologene: 28313
Osbpl6
Name: oxysterol binding protein-like 6
Synonyms: 1110062M20Rik, ORP-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99031
Homologene: 101447
Zbtb4
Name: zinc finger and BTB domain containing 4
Synonyms: 9230111I22Rik, 2310026P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 75580
Homologene: 10846
Myo15b
Name: myosin XVB
Synonyms: LOC380737, LOC217328, E330039G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217328
Acad9
Name: acyl-Coenzyme A dehydrogenase family, member 9
Synonyms: C630012L17Rik, 2600017P15Rik, NPD002
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229211
Homologene: 8539
Cav1
Name: caveolin 1, caveolae protein
Synonyms: Cav-1, caveolin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12389
HGNC: HGNC:1527
Homologene: 1330
Ddx31
Name: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31
Synonyms: 5830444G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227674
Homologene: 6389
Kcnk3
Name: potassium channel, subfamily K, member 3
Synonyms: Task-1, cTBAK-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16527
HGNC: HGNC:6278
Homologene: 1692
Tead2
Name: TEA domain family member 2
Synonyms: TEAD-2, TEF-4, Etdf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 21677
Homologene: 19662
Gpr141b
Name: G protein-coupled receptor 141B
Synonyms: A530099J19Rik, Karma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 319293
Homologene: 105930
Acsm2
Name: acyl-CoA synthetase medium-chain family member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233799
Homologene: 70404
Olfr1012
Name: olfactory receptor 1012
Synonyms: GA_x6K02T2Q125-47239120-47238185, MOR213-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258561
Homologene: 64889
Akp3
Name: alkaline phosphatase 3, intestine, not Mn requiring
Synonyms: IAP, Akp-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11648
Homologene: 134333
Mpg
Name: N-methylpurine-DNA glycosylase
Synonyms: Aag, APNG, Mid1, alkylpurine-DNA-N-glycosylase, 3-methyladenine DNA glycosylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 268395
HGNC: HGNC:7211
Homologene: 1824
Mgat5
Name: mannoside acetylglucosaminyltransferase 5
Synonyms: 5330407H02Rik, 4930471A21Rik, beta1,6N-acetylglucosaminyltransferase V, GlcNAc-TV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 107895
HGNC: HGNC:7049
Homologene: 1808
Scnm1
Name: sodium channel modifier 1
Synonyms: 3110001I17Rik, Scnm1-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 69269
Homologene: 11431
Olfr1
Name: olfactory receptor 1
Synonyms: I54, MOR135-13, GA_x6K02T2P1NL-3556334-3555390
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258923
Homologene: 115482
Rptn
Name: repetin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20129
Homologene: 84780
Sertad2
Name: SERTA domain containing 2
Synonyms: Trip-Br2, Sei2, SEI-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 58172
Homologene: 8843
Pacc1
Name: proton activated chloride channel 1
Synonyms: Tmem206, 2310028N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 66950
Homologene: 10097
Gm12258
Name: predicted gene 12258
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 108167848
Vsx1
Name: visual system homeobox 1
Synonyms: CHX10-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 114889
Homologene: 8743
Zdhhc4
Name: zinc finger, DHHC domain containing 4
Synonyms: 2900029I10Rik, 1810021D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 72881
Homologene: 10006
Ighv1-74
Name: immunoglobulin heavy variable V1-74
Synonyms: Gm16710
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 100775173
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 51,776,232 bp
  • T to C, chromosome 1 at 66,527,964 bp
  • T to C, chromosome 1 at 87,126,945 bp
  • T to C, chromosome 1 at 89,933,186 bp
  • C to A, chromosome 1 at 127,382,939 bp
  • A to G, chromosome 1 at 191,348,371 bp
  • A to T, chromosome 2 at 28,874,173 bp
  • A to G, chromosome 2 at 76,549,512 bp
  • G to T, chromosome 2 at 76,945,570 bp
  • A to G, chromosome 2 at 85,753,839 bp
  • T to C, chromosome 2 at 150,688,537 bp
  • A to G, chromosome 3 at 36,075,174 bp
  • A to G, chromosome 3 at 93,398,027 bp
  • T to C, chromosome 3 at 95,130,285 bp
  • C to T, chromosome 3 at 113,563,662 bp
  • A to T, chromosome 3 at 126,942,688 bp
  • T to C, chromosome 5 at 29,599,056 bp
  • T to G, chromosome 5 at 30,588,510 bp
  • T to C, chromosome 5 at 84,150,369 bp
  • C to T, chromosome 5 at 110,337,287 bp
  • G to A, chromosome 5 at 114,119,621 bp
  • A to G, chromosome 5 at 120,626,367 bp
  • A to T, chromosome 5 at 143,324,849 bp
  • C to T, chromosome 5 at 144,807,391 bp
  • T to G, chromosome 5 at 149,594,482 bp
  • C to A, chromosome 6 at 17,307,919 bp
  • C to A, chromosome 6 at 108,506,027 bp
  • C to A, chromosome 7 at 29,997,863 bp
  • T to C, chromosome 7 at 43,659,336 bp
  • T to A, chromosome 7 at 45,220,714 bp
  • T to C, chromosome 7 at 46,042,613 bp
  • T to C, chromosome 7 at 59,277,020 bp
  • T to C, chromosome 7 at 72,259,175 bp
  • A to G, chromosome 7 at 82,651,899 bp
  • T to C, chromosome 7 at 106,601,470 bp
  • T to C, chromosome 7 at 119,554,481 bp
  • T to C, chromosome 7 at 141,864,173 bp
  • A to G, chromosome 8 at 95,754,978 bp
  • A to G, chromosome 9 at 8,112,119 bp
  • A to G, chromosome 9 at 119,631,560 bp
  • G to A, chromosome 11 at 20,647,884 bp
  • T to C, chromosome 11 at 32,227,951 bp
  • G to A, chromosome 11 at 58,859,459 bp
  • A to G, chromosome 11 at 69,778,214 bp
  • AGCGGTCGTAGGC to AGC, chromosome 11 at 73,395,654 bp
  • G to A, chromosome 11 at 115,873,757 bp
  • T to A, chromosome 12 at 71,157,119 bp
  • T to A, chromosome 12 at 76,604,168 bp
  • T to A, chromosome 12 at 105,811,041 bp
  • C to A, chromosome 12 at 115,802,835 bp
  • T to G, chromosome 13 at 19,729,130 bp
  • C to A, chromosome 13 at 30,820,623 bp
  • T to A, chromosome 13 at 55,263,404 bp
  • C to A, chromosome 13 at 73,267,507 bp
  • T to C, chromosome 15 at 48,791,882 bp
  • A to G, chromosome 17 at 27,435,155 bp
  • A to G, chromosome 17 at 35,882,870 bp
  • A to T, chromosome 17 at 47,498,542 bp
  • T to A, chromosome 17 at 78,315,717 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5956 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044144-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.