Strain Name:
C57BL/6J-MtgxR6120Btlr
Stock Number:
044268-MU
Citation ID:
RRID:MMRRC_044268-MU
Other Names:
R6120 (G1)
Major Collection:

Gene Information

Sema3c
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Synonyms: 1110036B02Rik, Semae
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20348
Homologene: 36201
Chrna4
Name: cholinergic receptor, nicotinic, alpha polypeptide 4
Synonyms: Acra-4, Acra4, a4 nicotinic receptor, alpha4 nAChR, alpha4-nAChR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11438
HGNC: HGNC:1958
Homologene: 592
Bpifb3
Name: BPI fold containing family B, member 3
Synonyms: Rya3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 378700
Homologene: 18807
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: slip, DNA-PK, DNAPDcs, dxnph, DOXNPH, DNA-PKcs, XRCC7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Phr1, C130061D10Rik, Pam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105689
Homologene: 9005
Kif13b
Name: kinesin family member 13B
Synonyms: 5330429L19Rik, N-3 kinesin, GAKIN, C130021D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16554
VEGA: 14
Homologene: 9073
Rrm1
Name: ribonucleotide reductase M1
Synonyms: RnrM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20133
Homologene: 806
Gbf1
Name: golgi-specific brefeldin A-resistance factor 1
Synonyms: 1700083E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107338
HGNC: HGNC:4181
Homologene: 37897
Sgcb
Name: sarcoglycan, beta (dystrophin-associated glycoprotein)
Synonyms: beta-SG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 24051
Homologene: 195
Prmt2
Name: protein arginine N-methyltransferase 2
Synonyms: Hrmt1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 15468
HGNC: HGNC:5186
Homologene: 55587
Fgfr2
Name: fibroblast growth factor receptor 2
Synonyms: Fgfr-2, Fgfr7, Bek, KGFRTr, svs, Fgfr-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14183
HGNC: HGNC:3689
Homologene: 22566
Ms4a6b
Name: membrane-spanning 4-domains, subfamily A, member 6B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 69774
Homologene: 128306
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Psmc6
Name: proteasome (prosome, macropain) 26S subunit, ATPase, 6
Synonyms: 2300001E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 67089
VEGA: 14
HGNC: HGNC:9553
Homologene: 100630
Cnot3
Name: CCR4-NOT transcription complex, subunit 3
Synonyms: A930039N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232791
HGNC: HGNC:7879
Homologene: 133900
Fnip1
Name: folliculin interacting protein 1
Synonyms: A730024A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216742
Homologene: 28173
Gja1
Name: gap junction protein, alpha 1
Synonyms: connexin43, Gja-1, Cx43alpha1, Cx43, Cnx43, alpha 1 connexin, connexin 43
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14609
VEGA: 10
HGNC: HGNC:4274
Homologene: 136
Exosc9
Name: exosome component 9
Synonyms: p6, RRP45, Pmscl1, PM/Scl-75, p5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 50911
HGNC: HGNC:9137
Homologene: 3693
Pcsk2
Name: proprotein convertase subtilisin/kexin type 2
Synonyms: PC2, 6330411F23Rik, prohormone convertase 2, Phpp-2, SPC2, Nec-2, Nec2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18549
HGNC: HGNC:8744
Homologene: 37640
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Ush2a
Name: usherin
Synonyms: Ush2a, Ushrn, MUSH2A, A930037M10Rik, A930011D15Rik, LOC269160, LOC381317
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22283
Homologene: 66151
Wdr11
Name: WD repeat domain 11
Synonyms: 2900055P10Rik, Wdr11, Brwd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 207425
Homologene: 41229
Sync
Name: syncoilin
Synonyms: SNIP4, 1110057H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 68828
Homologene: 11351
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Csf1
Name: colony stimulating factor 1 (macrophage)
Synonyms: M-CSF, CSF-1, colony-stimulating factor-1, Csfm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12977
HGNC: HGNC:2432
Homologene: 7282
Vmn2r115
Name: vomeronasal 2, receptor 115
Synonyms: V2Rp4, EG638102
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 638102
HGNC: null
Homologene: 86604
Kif1a
Name: kinesin family member 1A
Synonyms: C630002N23Rik, ATSV, Kns1, LOC381283, N-3 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16560
HGNC: HGNC:888
Homologene: 99729
Eml1
Name: echinoderm microtubule associated protein like 1
Synonyms: ELP79, A930030P13Rik, heco, 1110008N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68519
HGNC: HGNC:3330
Homologene: 20931
Slc26a2
Name: solute carrier family 26 (sulfate transporter), member 2
Synonyms: ST-OB, Dtd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13521
Homologene: 73876
Csrp2
Name: cysteine and glycine-rich protein 2
Synonyms: Crp2, SmLim
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13008
VEGA: 10
HGNC: HGNC:2470
Homologene: 111061
Sh3pxd2a
Name: SH3 and PX domains 2A
Synonyms: 2310014D11Rik, Sh3md1, Tks5, Fish
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 14218
VEGA: 19
Homologene: 7317
Greb1
Name: gene regulated by estrogen in breast cancer protein
Synonyms: 5730583K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 268527
Homologene: 8780
Sspo
Name: SCO-spondin
Synonyms: C79529, Scospondin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 243369
Homologene: 45453
Fes
Name: feline sarcoma oncogene
Synonyms: c-fes
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14159
HGNC: HGNC:3657
Homologene: 37563
Ccdc178
Name: coiled coil domain containing 178
Synonyms: 4921528I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 70950
VEGA: 18
Homologene: 12373
Fam186a
Name: family with sequence similarity 186, member A
Synonyms: 1700030F18Rik, LOC380973
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 72277
Homologene: null
Vmn2r120
Name: vomeronasal 2, receptor 120
Synonyms: EG224916
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224916
HGNC: null
Homologene: null
Smarca5
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Synonyms: D030040M08Rik, MommeD4, Snf2h, 4933427E24Rik, D330027N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 93762
Homologene: 55764
Ccdc33
Name: coiled-coil domain containing 33
Synonyms: LOC382077, 4930535E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 382077
Homologene: 19641
Vcam1
Name: vascular cell adhesion molecule 1
Synonyms: CD106, Vcam-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 22329
Homologene: 838
Olfr1015
Name: olfactory receptor 1015
Synonyms: MOR213-3, GA_x6K02T2Q125-47264151-47265089
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258564
Homologene: 115499
Hook2
Name: hook microtubule tethering protein 2
Synonyms: A630054I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 170833
Homologene: 8332
Cdk14
Name: cyclin-dependent kinase 14
Synonyms: Pftk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18647
HGNC: HGNC:8883
Homologene: 7888
Vav3
Name: vav 3 oncogene
Synonyms: Idd18.1, A530094I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 57257
Homologene: 38143
Pira2
Name: paired-Ig-like receptor A2
Synonyms: 6M23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18725
HGNC: HGNC:6607
Homologene: 134028
4921524L21Rik
Name: RIKEN cDNA 4921524L21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 70901
VEGA: 18
HGNC: null
Homologene: 78009
Mkrn3
Name: makorin, ring finger protein, 3
Synonyms: D7H15S9-1, Zfp127
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22652
HGNC: HGNC:7114
Homologene: 4143
Olfr483
Name: olfactory receptor 483
Synonyms: GA_x6K02T2PBJ9-10432095-10433042, MOR204-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258730
HGNC: null
Homologene: 133602
Olfr811
Name: olfactory receptor 811
Synonyms: MOR110-6, GA_x6K02T2PULF-11481207-11480248
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258545
HGNC: null
Homologene: 133725
Mfsd1
Name: major facilitator superfamily domain containing 1
Synonyms: 1200003O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66868
Homologene: 11228
Pet100
Name: PET100 homolog
Synonyms: 2900053A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 100503890
Homologene: 87502
Gm5431
Name: predicted gene 5431
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 432555
HGNC: null
Homologene: null
Gpr20
Name: G protein-coupled receptor 20
Synonyms: A430106B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239530
HGNC: HGNC:4475
Homologene: 3870
Entpd2
Name: ectonucleoside triphosphate diphosphohydrolase 2
Synonyms: Cd39l1, NTPDase2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12496
HGNC: HGNC:3364
Homologene: 20333
Ankef1
Name: ankyrin repeat and EF-hand domain containing 1
Synonyms: Ankrd5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 319196
Homologene: 11130
Btd
Name: biotinidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 26363
HGNC: HGNC:1122
Homologene: 37255
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 93,024,574 bp
  • T to C, chromosome 1 at 188,358,603 bp
  • T to A, chromosome 2 at 25,399,466 bp
  • T to C, chromosome 2 at 85,786,341 bp
  • A to G, chromosome 2 at 136,550,376 bp
  • A to G, chromosome 2 at 143,801,111 bp
  • G to T, chromosome 2 at 153,931,443 bp
  • A to G, chromosome 2 at 181,024,806 bp
  • A to T, chromosome 3 at 36,554,672 bp
  • C to T, chromosome 3 at 67,594,385 bp
  • T to A, chromosome 3 at 107,753,854 bp
  • C to T, chromosome 3 at 109,664,365 bp
  • A to G, chromosome 3 at 116,124,400 bp
  • T to C, chromosome 4 at 129,293,751 bp
  • A to T, chromosome 5 at 4,894,029 bp
  • A to G, chromosome 5 at 17,727,632 bp
  • T to C, chromosome 5 at 73,640,810 bp
  • T to A, chromosome 6 at 48,465,576 bp
  • T to A, chromosome 7 at 3,645,336 bp
  • A to G, chromosome 7 at 3,841,554 bp
  • A to G, chromosome 7 at 62,419,534 bp
  • T to C, chromosome 7 at 80,380,867 bp
  • G to A, chromosome 7 at 102,460,856 bp
  • A to T, chromosome 7 at 108,104,133 bp
  • A to G, chromosome 7 at 129,624,791 bp
  • G to T, chromosome 7 at 130,228,690 bp
  • T to G, chromosome 8 at 3,621,764 bp
  • G to T, chromosome 8 at 80,711,743 bp
  • A to G, chromosome 8 at 84,998,125 bp
  • G to A, chromosome 9 at 58,086,600 bp
  • T to A, chromosome 10 at 56,388,505 bp
  • A to G, chromosome 10 at 76,209,446 bp
  • G to T, chromosome 10 at 110,939,279 bp
  • G to A, chromosome 10 at 129,801,820 bp
  • C to A, chromosome 10 at 129,801,821 bp
  • A to G, chromosome 11 at 48,894,781 bp
  • A to G, chromosome 11 at 54,510,000 bp
  • T to C, chromosome 11 at 66,147,399 bp
  • T to G, chromosome 12 at 16,708,621 bp
  • C to T, chromosome 12 at 108,527,724 bp
  • G to A, chromosome 14 at 31,641,108 bp
  • A to G, chromosome 14 at 45,348,673 bp
  • A to T, chromosome 14 at 64,751,558 bp
  • A to T, chromosome 14 at 103,275,887 bp
  • C to T, chromosome 15 at 73,696,004 bp
  • T to C, chromosome 15 at 99,940,363 bp
  • C to A, chromosome 16 at 15,739,471 bp
  • T to C, chromosome 16 at 32,756,795 bp
  • T to A, chromosome 17 at 23,346,029 bp
  • T to A, chromosome 17 at 57,525,973 bp
  • T to C, chromosome 17 at 67,780,617 bp
  • T to A, chromosome 18 at 6,638,795 bp
  • A to G, chromosome 18 at 22,097,728 bp
  • A to G, chromosome 18 at 61,199,417 bp
  • A to G, chromosome 19 at 11,521,695 bp
  • A to G, chromosome 19 at 46,279,321 bp
  • A to G, chromosome 19 at 47,267,409 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6120 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044268-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.