Strain Name:
C57BL/6J-MtgxR6790Btlr/Mmmh
Stock Number:
044903-MU
Citation ID:
RRID:MMRRC_044903-MU
Other Names:
R6790 (G1)
Major Collection:

Strain Information

Mga
Name: MAX gene associated
Synonyms: Mad5, D030062C11Rik, Mga, C130042M01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 29808
Homologene: 49351
Gon4l
Name: gon-4 like
Synonyms: 2610100B20Rik, 1500041I23Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76022
Homologene: 13002
Secisbp2
Name: SECIS binding protein 2
Synonyms: 2810012K13Rik, 2210413N07Rik, SBP2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75420
Homologene: 11415
Kdm4c
Name: lysine (K)-specific demethylase 4C
Synonyms: Jmjd2c, 2410141F18Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76804
Homologene: 41004
Slk
Name: STE20-like kinase
Synonyms: mSLK, Etk4, SLK, Stk2, 9A2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20874
Homologene: 22515
Ascc3
Name: activating signal cointegrator 1 complex subunit 3
Synonyms: B630009I04Rik, ASC1p200, Helic1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 77987
VEGA: 10
Homologene: 4973
Fkbp15
Name: FK506 binding protein 15
Synonyms: FKBP133, C430014M02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 338355
Homologene: 28743
Crh
Name: corticotropin releasing hormone
Synonyms: LOC383938, CRF, corticotropin-releasing factor, corticotropin releasing factor
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12918
HGNC: HGNC:2355
Homologene: 599
Stmn1
Name: stathmin 1
Synonyms: metablastin, SMN, PR22, PP18, PP17, Lag, op18, Lap18, 19K, p19, pig, p18, prosolin, leukemia associated phosphoprotein p18, oncoprotein18
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16765
HGNC: HGNC:6510
Homologene: 4063
Zdhhc20
Name: zinc finger, DHHC domain containing 20
Synonyms: B230110O18Rik, ENSMUSG00000055956, 4930542A17Rik, 5033406L14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 75965
VEGA: 14
Homologene: 57105
Adgrf3
Name: adhesion G protein-coupled receptor F3
Synonyms: LOC381628, Gpr113, PGR23
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381628
Homologene: 17826
Lrrc20
Name: leucine rich repeat containing 20
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216011
VEGA: 10
Homologene: 45208
Eng
Name: endoglin
Synonyms: Endo, CD105
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13805
HGNC: HGNC:3349
Homologene: 92
Cfap97
Name: cilia and flagella associated protein 97
Synonyms: 4933411K20Rik, 1110068E21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66756
Homologene: 12026
Cx3cr1
Name: C-X3-C motif chemokine receptor 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13051
VEGA: 9
HGNC: HGNC:2558
Homologene: 20350
Itga4
Name: integrin alpha 4
Synonyms: VLA-4 receptor, alpha 4 subunit
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16401
HGNC: HGNC:6140
Homologene: 37364
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Per2
Name: period circadian clock 2
Synonyms: mPer2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18627
HGNC: HGNC:8846
Homologene: 7885
Ankrd65
Name: ankyrin repeat domain 65
Synonyms: E230028L10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242805
Homologene: 28427
Rims1
Name: regulating synaptic membrane exocytosis 1
Synonyms: RIM1alpha, RIM1a, C030033M19Rik, RIM1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 116837
Homologene: 128399
Ugt8a
Name: UDP galactosyltransferase 8A
Synonyms: Ugt8, mCerGT, Cgt
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 22239
Homologene: 20715
Slc8a3
Name: solute carrier family 8 (sodium/calcium exchanger), member 3
Synonyms: Ncx3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 110893
Homologene: 62645
Npc1l1
Name: NPC1 like intracellular cholesterol transporter 1
Synonyms: 9130221N23Rik, Niemann-Pick disease, type C1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237636
HGNC: HGNC:7898
Homologene: 56585
Hrnr
Name: hornerin
Synonyms: A530063N20Rik, S100a18, 1110033K19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 68723
Homologene: 138092
Acap3
Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
Synonyms: Centb5, Kiaa1716-hp
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 140500
Homologene: 23708
Cyp3a59
Name: cytochrome P450, family 3, subfamily a, polypeptide 59
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100041449
Homologene: 135775
Dnm1
Name: dynamin 1
Synonyms: dynamin 1, Ftfl
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13429
HGNC: HGNC:2972
Homologene: 123905
Slc28a3
Name: solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
Synonyms: Cnt3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 114304
Homologene: 32533
Nup50l
Name: nucleoporin 50 like
Synonyms: 1700123L14Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 78482
HGNC: HGNC:8065
Atf5
Name: activating transcription factor 5
Synonyms: ODA-10, Atfx, Atf7, AFTA
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 107503
HGNC: HGNC:790
Homologene: 32142
Pira2
Name: paired-Ig-like receptor A2
Synonyms: 6M23
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18725
Homologene: 134028
Or3a1b
Name: olfactory receptor family 3 subfamily A member 1B
Synonyms: GA_x6K02T2P1NL-4278037-4278984, MOR255-6, Olfr401
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258701
HGNC: HGNC:8282
Homologene: 73922
Pate13
Name: prostate and testis expressed 13
Synonyms: 9230113P08Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 77908
Tuft1
Name: tuftelin 1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 22156
Homologene: 7985
Potefam3e
Name: POTE ankyrin domain family member 3E
Synonyms: OTTMUSG00000018948, 4930467E23Rik, TSAP, ENSMUSG00000074453, Pote3e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 626415
Homologene: 128726
Gm21149
Name: predicted gene, 21149
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100861702
Homologene: 69402
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 22,468,197 bp
  • C to T, chromosome 1 at 91,445,539 bp
  • T to C, chromosome 2 at 32,333,067 bp
  • C to A, chromosome 2 at 32,669,445 bp
  • C to A, chromosome 2 at 79,325,614 bp
  • A to G, chromosome 2 at 82,990,939 bp
  • A to G, chromosome 2 at 119,923,754 bp
  • T to G, chromosome 3 at 19,694,295 bp
  • A to G, chromosome 3 at 88,858,998 bp
  • T to C, chromosome 3 at 93,329,075 bp
  • C to G, chromosome 3 at 94,628,230 bp
  • T to C, chromosome 3 at 125,871,691 bp
  • T to C, chromosome 4 at 62,304,759 bp
  • A to G, chromosome 4 at 74,391,461 bp
  • T to C, chromosome 4 at 134,470,814 bp
  • T to G, chromosome 4 at 155,792,803 bp
  • T to A, chromosome 4 at 155,902,991 bp
  • A to C, chromosome 5 at 15,472,105 bp
  • A to G, chromosome 5 at 30,196,387 bp
  • A to C, chromosome 5 at 146,096,333 bp
  • T to C, chromosome 6 at 96,165,323 bp
  • A to C, chromosome 7 at 3,842,443 bp
  • A to T, chromosome 7 at 44,813,255 bp
  • A to T, chromosome 8 at 19,729,785 bp
  • G to T, chromosome 8 at 46,170,076 bp
  • G to T, chromosome 9 at 35,908,831 bp
  • C to T, chromosome 9 at 120,051,767 bp
  • A to G, chromosome 10 at 50,645,712 bp
  • G to T, chromosome 10 at 61,527,119 bp
  • C to T, chromosome 11 at 6,214,260 bp
  • T to A, chromosome 11 at 74,121,601 bp
  • T to C, chromosome 12 at 81,314,432 bp
  • A to G, chromosome 13 at 51,670,903 bp
  • T to C, chromosome 13 at 58,582,650 bp
  • A to G, chromosome 14 at 57,890,143 bp
  • T to A, chromosome 19 at 47,635,568 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6790 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044903-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.