Strain Name:
C57BL/6J-MtgxR7900Btlr/Mmmh
Stock Number:
045952-MU
Citation ID:
RRID:MMRRC_045952-MU
Other Names:
R7900 (G1)
Major Collection:

Strain Information

Camk2a
Name: calcium/calmodulin-dependent protein kinase II alpha
Synonyms: alpha-CaMKII
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12322
HGNC: HGNC:1460
Homologene: 56577
Ctbp2
Name: C-terminal binding protein 2
Synonyms: Ribeye, D7Ertd45e, Gtrgeo6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13017
HGNC: HGNC:2495
Homologene: 75187
Ranbp1
Name: RAN binding protein 1
Synonyms: Htf9a
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19385
HGNC: HGNC:9847
Homologene: 21600
Cwf19l2
Name: CWF19 like cell cycle control factor 2
Synonyms: 3230401L03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244672
Homologene: 12366
Efr3a
Name: EFR3 homolog A
Synonyms: A130089M23Rik, D030063F01Rik, C920006C10Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 76740
Homologene: 44222
Cnst
Name: consortin, connexin sorting protein
Synonyms: 9630058J23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226744
Homologene: 17139
Dock9
Name: dedicator of cytokinesis 9
Synonyms: B230309H04Rik, D14Wsu89e, Zizimin1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105445
Homologene: 41026
Prkd2
Name: protein kinase D2
Synonyms: PKD2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101540
Homologene: 9516
Washc4
Name: WASH complex subunit 4
Synonyms: A230046K03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 319277
VEGA: 10
Homologene: 123926
Trpm7
Name: transient receptor potential cation channel, subfamily M, member 7
Synonyms: 5033407O22Rik, 4833414K03Rik, Ltpr7, CHAK1, CHAK, TRP-PLIK, 2310022G15Rik, LTRPC7
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 58800
Homologene: 9774
Usp24
Name: ubiquitin specific peptidase 24
Synonyms: 2810030C21Rik, 2700066K03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329908
Homologene: 35420
Smurf1
Name: SMAD specific E3 ubiquitin protein ligase 1
Synonyms: 4930431E10Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75788
Homologene: 10712
Tmem245
Name: transmembrane protein 245
Synonyms: A630051L19Rik, D730040F13Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242474
HGNC: HGNC:1363
Homologene: 41841
Lhx4
Name: LIM homeobox protein 4
Synonyms: Gsh-4, Gsh4, A330062J17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16872
Homologene: 56497
Dlst
Name: dihydrolipoamide S-succinyltransferase
Synonyms: 4930529O08Rik, 1600017E01Rik, 4632413C10Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 78920
VEGA: 12
HGNC: HGNC:2911
Homologene: 1456
Tpd52l1
Name: tumor protein D52-like 1
Synonyms: D53
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 21987
VEGA: 10
Homologene: 2468
Gpihbp1
Name: GPI-anchored HDL-binding protein 1
Synonyms: GPI-HBP1, 1110002J19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 68453
Homologene: 136164
Zfy1
Name: zinc finger protein 1, Y-linked
Synonyms: Zfy-1
Type: Gene
Species: Mouse
Chromosome: Y
NCBI: 22767
Homologene: 56456
Ddx3y
Name: DEAD box helicase 3, Y-linked
Synonyms: Dby, 8030469F12Rik, D1Pas1-rs1, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
Type: Gene
Species: Mouse
Chromosome: Y
NCBI: 26900
HGNC: HGNC:2699
Homologene: 55839
Yeats4
Name: YEATS domain containing 4
Synonyms: NuBI-1, 4930573H17Rik, GAS41, B230215M10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64050
VEGA: 10
Homologene: 4760
Egln1
Name: egl-9 family hypoxia-inducible factor 1
Synonyms: SM-20, ORF13, Phd2, Hif-p4h-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 112405
HGNC: HGNC:1232
Homologene: 56936
Gjc1
Name: gap junction protein, gamma 1
Synonyms: connexin 45, Cx45, Gja-7, C130009G16Rik, Gja7
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14615
HGNC: HGNC:4280
Homologene: 4016
Nr1d1
Name: nuclear receptor subfamily 1, group D, member 1
Synonyms: A530070C09Rik, REV-ERBalpha, rev-erbA(alpha)
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217166
HGNC: HGNC:7962
Homologene: 23324
Sec31b
Name: SEC31 homolog B, COPII coat complex component
Synonyms: LOC240667, Sec31l2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240667
Homologene: 56708
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: D330014H01Rik, 2900022L05Rik, Dnhd3, Dnahc2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Vwf
Name: Von Willebrand factor
Synonyms: B130011O06Rik, 6820430P06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22371
Homologene: 466
Nxnl1
Name: nucleoredoxin-like 1
Synonyms: RdCVF, A930031O08Rik, Txnl6
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234404
Homologene: 89165
Lrguk
Name: leucine-rich repeats and guanylate kinase domain containing
Synonyms: 4921528H16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74354
Homologene: 34923
Specc1
Name: sperm antigen with calponin homology and coiled-coil domains 1
Synonyms: B230396K10Rik, 2810012G08Rik, Cytsb
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 432572
Homologene: 45157
Zbtb38
Name: zinc finger and BTB domain containing 38
Synonyms: A930014K01Rik, Zenon homolog, CIBZ
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245007
Homologene: 19529
Gata3
Name: GATA binding protein 3
Synonyms: Gata-3, jal
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14462
HGNC: HGNC:4172
Homologene: 1550
C4b
Name: complement C4B (Chido blood group)
Synonyms: Ss, C4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12268
Homologene: 36030
Dnm3
Name: dynamin 3
Synonyms: B230343F03Rik, 9630020E24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 103967
Homologene: 22906
Tecrl
Name: trans-2,3-enoyl-CoA reductase-like
Synonyms: D330017N19Rik, Srd5a2l2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243078
Homologene: 27549
Mmp1a
Name: matrix metallopeptidase 1a (interstitial collagenase)
Synonyms: Mcol-A
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 83995
VEGA: 9
HGNC: HGNC:7155
Homologene: 20544
Pla2r1
Name: phospholipase A2 receptor 1
Synonyms: PLA2-I receptor, M-type receptor, Pla2g1br
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18779
HGNC: HGNC:9042
Homologene: 32016
Slc6a19
Name: solute carrier family 6 (neurotransmitter transporter), member 19
Synonyms: B0AT1, 4632401C08Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 74338
Homologene: 52819
Onecut2
Name: one cut domain, family member 2
Synonyms: OC-2, Oc2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225631
HGNC: HGNC:8139
Homologene: 113592
Gpnmb
Name: glycoprotein (transmembrane) nmb
Synonyms: Dchil, Osteoactivin, DC-HIL
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 93695
HGNC: HGNC:4462
Homologene: 1880
Usp9y
Name: ubiquitin specific peptidase 9, Y chromosome
Synonyms: Dffry, Fafl2
Type: Gene
Species: Mouse
Chromosome: Y
NCBI: 107868
Homologene: 68408
Cyp11a1
Name: cytochrome P450, family 11, subfamily a, polypeptide 1
Synonyms: P450scc, D9Ertd411e, cholesterol side chain cleavage, Cyp11a, Scc, cscc
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13070
HGNC: HGNC:2590
Homologene: 37347
Ankle1
Name: ankyrin repeat and LEM domain containing 1
Synonyms: 8430438L13Rik, Ankrd41
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234396
Homologene: 17562
Gpcpd1
Name: glycerophosphocholine phosphodiesterase 1
Synonyms: 2310032D16Rik, 2310004G06Rik, Prei4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74182
Homologene: 10478
Or5an1
Name: olfactory receptor family 5 subfamily AN member 1
Synonyms: GA_x6K02T2RE5P-2618516-2619454, GA_x6K02T2RE5P-2610001-2610414, MOR214-4, MOR214-4, Olfr1433, Olfr1434
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258680
Homologene: 45029
Or51v14
Name: olfactory receptor family 51 subfamily V member 14
Synonyms: GA_x6K02T2PBJ9-6335095-6334154, MOR4-1, Olfr620
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258808
Homologene: 103777
A530084C06Rik
Name: RIKEN cDNA A530084C06 gene
Type: Gene
Species: Mouse
Chromosome: 13
Adamtsl5
Name: ADAMTS-like 5
Synonyms: 2010109H09Rik, Thsd6
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66548
Homologene: 19803
Tas2r136
Name: taste receptor, type 2, member 136
Synonyms: mt2r52, Tas2r36
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 353165
Homologene: 136304
Itpka
Name: inositol 1,4,5-trisphosphate 3-kinase A
Synonyms: IP3-kinase A
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228550
HGNC: HGNC:6178
Homologene: 1671
Retnla
Name: resistin like alpha
Synonyms: RELMa, 1810019L16Rik, Fizz1, Xcp2, HIMF, Fizz-1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 57262
VEGA: 16
Homologene: 23232
Trbv2
Name: T cell receptor beta, variable 2
Synonyms: Gm16752, Tcrb-V4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 100124659
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 155,741,963 bp
  • T to A, chromosome 1 at 162,355,371 bp
  • A to G, chromosome 1 at 179,622,888 bp
  • T to A, chromosome 2 at 9,858,650 bp
  • T to C, chromosome 2 at 60,428,514 bp
  • A to T, chromosome 2 at 119,750,513 bp
  • T to C, chromosome 2 at 126,797,498 bp
  • T to C, chromosome 2 at 132,534,739 bp
  • A to G, chromosome 4 at 56,924,973 bp
  • A to G, chromosome 4 at 106,409,400 bp
  • A to C, chromosome 5 at 83,279,341 bp
  • T to C, chromosome 5 at 144,899,373 bp
  • T to C, chromosome 6 at 34,129,194 bp
  • A to G, chromosome 6 at 41,047,974 bp
  • A to T, chromosome 6 at 49,050,466 bp
  • G to A, chromosome 6 at 125,628,476 bp
  • T to A, chromosome 6 at 132,777,636 bp
  • T to C, chromosome 7 at 16,853,344 bp
  • T to C, chromosome 7 at 103,611,693 bp
  • A to C, chromosome 7 at 133,014,599 bp
  • C to T, chromosome 8 at 71,407,417 bp
  • A to T, chromosome 8 at 71,566,526 bp
  • A to T, chromosome 8 at 124,914,140 bp
  • G to T, chromosome 9 at 3,460,107 bp
  • TG to TGG, chromosome 9 at 7,465,083 bp
  • T to A, chromosome 9 at 58,016,384 bp
  • A to C, chromosome 9 at 96,688,936 bp
  • T to A, chromosome 10 at 31,338,182 bp
  • A to G, chromosome 10 at 80,341,901 bp
  • T to A, chromosome 10 at 83,573,773 bp
  • G to A, chromosome 10 at 117,220,559 bp
  • A to G, chromosome 11 at 62,219,361 bp
  • A to G, chromosome 11 at 69,518,428 bp
  • T to A, chromosome 11 at 98,769,711 bp
  • T to C, chromosome 11 at 102,800,094 bp
  • G to T, chromosome 12 at 85,130,518 bp
  • G to T, chromosome 13 at 31,558,995 bp
  • C to T, chromosome 13 at 73,700,464 bp
  • C to T, chromosome 14 at 121,546,079 bp
  • T to A, chromosome 15 at 65,848,135 bp
  • T to C, chromosome 15 at 75,597,942 bp
  • T to C, chromosome 16 at 18,245,297 bp
  • A to C, chromosome 16 at 48,843,614 bp
  • A to G, chromosome 17 at 34,739,777 bp
  • A to G, chromosome 18 at 60,957,366 bp
  • G to T, chromosome 18 at 64,341,587 bp
  • T to A, chromosome 19 at 12,283,341 bp
  • A to T, chromosome 19 at 44,526,230 bp
  • T to C, chromosome Y at 725,519 bp
  • C to T, chromosome Y at 1,266,594 bp
  • A to T, chromosome Y at 1,384,354 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7900 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045952-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.