Strain Name:
C57BL/6J-MtgxR9045Btlr/Mmmh
Stock Number:
068872-MU
Citation ID:
RRID:MMRRC_068872-MU
Other Names:
R9045 (G1)
Major Collection:

Strain Information

Fbxo36
Name: F-box protein 36
Synonyms: D1Ertd757e, 2410002G19Rik, 1110020F21Rik, 0610008D19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66153
Homologene: 11927
Fryl
Name: FRY like transcription coactivator
Synonyms: 2310004H21Rik, 9030227G01Rik, 2510002A14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72313
Homologene: 103956
S1pr2
Name: sphingosine-1-phosphate receptor 2
Synonyms: H218, 1100001A16Rik, Gpcr13, Edg5, S1P2, LPb2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14739
VEGA: 9
HGNC: HGNC:3169
Homologene: 3118
Scg3
Name: secretogranin III
Synonyms: 1B1075, SgIII, Chgd
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20255
VEGA: 9
Homologene: 7526
Cnot2
Name: CCR4-NOT transcription complex, subunit 2
Synonyms: 2600016M12Rik, 2810470K03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 72068
HGNC: HGNC:7878
Homologene: 40953
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: D5Ertd66e, Bwf1, 2610509D04Rik, Bchs, Ggtb3, Alfy
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72145
Homologene: 22855
Rps6ka1
Name: ribosomal protein S6 kinase polypeptide 1
Synonyms: Rsk1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20111
Homologene: 55703
Med13l
Name: mediator complex subunit 13-like
Synonyms: 9030618F05Rik, Trap240L, Thrap2, 6330591G05Rik, 2210413I17Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76199
Homologene: 25256
Sbno1
Name: strawberry notch 1
Synonyms: sno, 9330180L10Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243272
Homologene: 10055
Mcph1
Name: microcephaly, primary autosomal recessive 1
Synonyms: BRIT1, 5430437K10Rik, D030046N04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244329
HGNC: HGNC:6954
Homologene: 32586
Heatr1
Name: HEAT repeat containing 1
Synonyms: B130016L12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 217995
VEGA: 13
Homologene: 34562
Otud7b
Name: OTU domain containing 7B
Synonyms: Za20d1, 2900060B22Rik, 4930463P07Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229603
Homologene: 10624
Cyth1
Name: cytohesin 1
Synonyms: CTH-1, Pscd1, CLM1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19157
HGNC: HGNC:9501
Homologene: 31262
Zfp180
Name: zinc finger protein 180
Synonyms: HHZ168, D130011P11, 2310040I01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210135
Homologene: 8306
Lrig1
Name: leucine-rich repeats and immunoglobulin-like domains 1
Synonyms: LIG-1, Img
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16206
Homologene: 7380
Golga3
Name: golgin A3
Synonyms: 5430416E01Rik, G1-499-14, repro27, Mea-2, Mea2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269682
HGNC: HGNC:4426
Homologene: 4308
Epg5
Name: ectopic P-granules 5 autophagy tethering factor
Synonyms: 5430411K18Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 100502841
VEGA: 18
Homologene: 14575
Zfp846
Name: zinc finger protein 846
Synonyms: 2210010B09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244721
Homologene: 87243
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Npat
Name: nuclear protein in the AT region
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244879
HGNC: HGNC:7896
Homologene: 1888
Zfc3h1
Name: zinc finger, C3H1-type containing
Synonyms: Psrc2, Ccdc131
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216345
Homologene: 17017
Slamf9
Name: SLAM family member 9
Synonyms: CD84-H1, 2310026I04Rik, CD2F-10, SF2001, Cd2f10
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98365
Homologene: 12642
Tmem52
Name: transmembrane protein 52
Synonyms: 2310043I08Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69671
Homologene: 18680
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 94109
Homologene: 69536
Nr4a3
Name: nuclear receptor subfamily 4, group A, member 3
Synonyms: Nor1, MINOR, NOR-1, TEC
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18124
HGNC: HGNC:7982
Homologene: 5074
Tas2r124
Name: taste receptor, type 2, member 124
Synonyms: mGR24, T2R24, mt2r50, Tas2r24
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387351
Homologene: 87293
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Gckr
Name: glucokinase regulatory protein
Synonyms: GKRP
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231103
HGNC: HGNC:4196
Homologene: 1139
Bbs7
Name: Bardet-Biedl syndrome 7
Synonyms: 8430406N16Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71492
Homologene: 12395
Fcgbpl1
Name: Fc fragment of IgG binding protein like 1
Synonyms: 9530053A07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 319482
Homologene: 130055
Vmn2r102
Name: vomeronasal 2, receptor 102
Synonyms: EG224572
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224572
Homologene: 115024
Clstn3
Name: calsyntenin 3
Synonyms: Cst-3, alcadein-beta, CSTN3, Clstn3b
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232370
Homologene: 22836
Myo15b
Name: myosin XVB
Synonyms: LOC380737, E330039G21Rik, LOC217328
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217328
Serpinb1c
Name: serine (or cysteine) peptidase inhibitor, clade B, member 1c
Synonyms: ovalbumin, EIC
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 380839
HGNC: HGNC:3311
Homologene: 137840
Vwa5b1
Name: von Willebrand factor A domain containing 5B1
Synonyms: 4931403E03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 75718
Homologene: 19431
Vmn2r58
Name: vomeronasal 2, receptor 58
Synonyms: EG628422
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 628422
Wdhd1
Name: WD repeat and HMG-box DNA binding protein 1
Synonyms: AND-1, D630024B06Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218973
Homologene: 56019
Nr2c2ap
Name: nuclear receptor 2C2-associated protein
Synonyms: 2310073E15Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 75692
Homologene: 18532
Laptm5
Name: lysosomal-associated protein transmembrane 5
Synonyms: E3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16792
Homologene: 4922
5930422O12Rik
Name: RIKEN cDNA 5930422O12 gene
Type: Gene
Species: Mouse
Chromosome: 8
Grip1
Name: glutamate receptor interacting protein 1
Synonyms: eb, 4931400F03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74053
Homologene: 12938
9130401M01Rik
Name: RIKEN cDNA 9130401M01 gene
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75758
Homologene: 12622
Tgm4
Name: transglutaminase 4 (prostate)
Synonyms: 9530008N10Rik, experimental autoimmune prostatitis antigen 1, Eapa1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 331046
Homologene: 20689
Flot2
Name: flotillin 2
Synonyms: reggie-2, Esa
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14252
HGNC: HGNC:3758
Homologene: 3293
Atxn7l3
Name: ataxin 7-like 3
Synonyms: E030022H21Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217218
Homologene: 35401
Cr2
Name: complement receptor 2
Synonyms: CD35, Cr-2, Cr1, C3DR, CD21, Cr-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12902
HGNC: HGNC:2336
Homologene: 55611
Mindy4
Name: MINDY lysine 48 deubiquitinase 4
Synonyms: Fam188b, LOC384387, C330043M08Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330323
Homologene: 49991
Or5h25
Name: olfactory receptor family 5 subfamily H member 25
Synonyms: Olfr1540-ps1, MOR113-7P, MOR183-7P, Olfr193, MOR113-7P, GA_x54KRFPKG5P-55338697-55337768
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 257972
Homologene: 128162
Or52ab4
Name: olfactory receptor family 52 subfamily AB member 4
Synonyms: GA_x6K02T2PBJ9-6047402-6048349, MOR23-1, Olfr599
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258726
Homologene: 27244
Pafah1b3
Name: platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
Synonyms: mus[g], Pafahg, PAF-AH alpha1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18476
HGNC: HGNC:8576
Homologene: 1933
Adgra1
Name: adhesion G protein-coupled receptor A1
Synonyms: D7Ertd680e, 2900059M17Rik, Gpr123
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 52389
Homologene: 18582
Cela3b
Name: chymotrypsin-like elastase family, member 3B
Synonyms: Ela3b, 0910001F22Rik, Ela3, 2310074F01Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67868
Homologene: 128227
Pira12
Name: paired-Ig-like receptor A12
Synonyms: Gm14548
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100038909
Homologene: 134028
Pde2a
Name: phosphodiesterase 2A, cGMP-stimulated
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 207728
HGNC: HGNC:8777
Homologene: 1952
Or12e10
Name: olfactory receptor family 12 subfamily E member 10
Synonyms: Olfr1145, MOR264-19, GA_x6K02T2Q125-49311440-49312384
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258317
Homologene: 27123
Aida
Name: axin interactor, dorsalization associated
Synonyms: 2610208M17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108909
Homologene: 11268
Sh2d6
Name: SH2 domain containing 6
Synonyms: 4933424C13Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71130
Homologene: 65986
Nfkbie
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18037
VEGA: 17
HGNC: HGNC:7799
Homologene: 36160
Slc50a1
Name: solute carrier family 50 (sugar transporter), member 1
Synonyms: Rga, Rag1ap1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 19729
Homologene: 40647
Vstm2l
Name: V-set and transmembrane domain containing 2-like
Synonyms: LOC277432
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 277432
Homologene: 15414
Rbfa
Name: ribosome binding factor A
Synonyms: 1110032A13Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 68731
VEGA: 18
Homologene: 11725
Rhox3c
Name: reproductive homeobox 3C
Synonyms: EG665203
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 100135654
Homologene: 83502
Pcdhgc3
Name: protocadherin gamma subfamily C, 3
Synonyms: Pcdh2, PC43
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93706
HGNC: HGNC:8716
Homologene: 31099
Krtap10-23
Name: keratin associated protein 10-23
Synonyms: Gm3250
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 100041281
VEGA: 10
Homologene: 115744
Iglv1
Name: immunoglobulin lambda variable 1
Synonyms: 1810027O01Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 16142
Ankrd31
Name: ankyrin repeat domain 31
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 625662
Homologene: 110355
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 84,896,579 bp
  • G to A, chromosome 1 at 172,477,371 bp
  • A to G, chromosome 1 at 183,314,005 bp
  • A to T, chromosome 1 at 195,155,372 bp
  • C to A, chromosome 2 at 87,810,072 bp
  • G to T, chromosome 2 at 157,914,875 bp
  • A to G, chromosome 3 at 36,612,035 bp
  • T to C, chromosome 3 at 89,268,735 bp
  • A to G, chromosome 3 at 96,152,578 bp
  • C to A, chromosome 4 at 48,067,694 bp
  • A to T, chromosome 4 at 130,928,644 bp
  • C to T, chromosome 4 at 133,872,839 bp
  • A to T, chromosome 4 at 137,424,799 bp
  • T to A, chromosome 4 at 138,588,679 bp
  • A to G, chromosome 4 at 155,469,442 bp
  • A to G, chromosome 5 at 31,300,009 bp
  • A to G, chromosome 5 at 73,024,775 bp
  • A to T, chromosome 5 at 101,847,174 bp
  • G to A, chromosome 5 at 110,193,097 bp
  • G to T, chromosome 5 at 118,742,751 bp
  • A to G, chromosome 5 at 124,405,657 bp
  • A to G, chromosome 6 at 55,318,298 bp
  • C to T, chromosome 6 at 72,515,621 bp
  • A to G, chromosome 6 at 94,608,707 bp
  • A to C, chromosome 6 at 124,431,962 bp
  • G to C, chromosome 6 at 132,755,071 bp
  • A to G, chromosome 7 at 3,894,548 bp
  • G to A, chromosome 7 at 24,104,890 bp
  • G to T, chromosome 7 at 25,297,473 bp
  • T to A, chromosome 7 at 28,154,431 bp
  • T to C, chromosome 7 at 41,837,663 bp
  • A to G, chromosome 7 at 101,503,291 bp
  • T to G, chromosome 7 at 103,338,696 bp
  • T to G, chromosome 7 at 139,852,650 bp
  • A to G, chromosome 8 at 16,234,074 bp
  • T to G, chromosome 8 at 18,632,427 bp
  • A to C, chromosome 8 at 33,429,334 bp
  • A to G, chromosome 8 at 70,133,158 bp
  • A to T, chromosome 9 at 20,593,893 bp
  • T to C, chromosome 9 at 20,967,594 bp
  • A to G, chromosome 9 at 53,563,476 bp
  • T to C, chromosome 9 at 75,663,240 bp
  • T to A, chromosome 9 at 79,674,752 bp
  • C to T, chromosome 9 at 123,048,551 bp
  • T to A, chromosome 10 at 77,782,098 bp
  • C to A, chromosome 10 at 115,427,414 bp
  • T to C, chromosome 10 at 116,486,255 bp
  • T to A, chromosome 10 at 120,035,451 bp
  • A to G, chromosome 11 at 78,059,197 bp
  • T to A, chromosome 11 at 102,292,446 bp
  • T to A, chromosome 11 at 115,892,352 bp
  • T to C, chromosome 11 at 118,182,264 bp
  • G to A, chromosome 12 at 115,193,880 bp
  • T to C, chromosome 13 at 12,413,352 bp
  • C to G, chromosome 13 at 32,882,044 bp
  • T to A, chromosome 13 at 96,831,526 bp
  • A to G, chromosome 14 at 47,273,952 bp
  • G to T, chromosome 15 at 58,028,734 bp
  • A to G, chromosome 16 at 19,085,303 bp
  • A to G, chromosome 16 at 59,110,002 bp
  • A to G, chromosome 17 at 19,660,579 bp
  • A to T, chromosome 17 at 45,562,033 bp
  • A to T, chromosome 17 at 67,753,843 bp
  • G to T, chromosome 18 at 37,807,616 bp
  • T to C, chromosome 18 at 77,948,799 bp
  • T to C, chromosome 18 at 80,192,811 bp
  • C to T, chromosome X at 37,469,650 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9045 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068872-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.