Strain Name:
C57BL/6J-MtgxR9330Btlr/Mmmh
Stock Number:
069142-MU
Citation ID:
RRID:MMRRC_069142-MU
Other Names:
R9330 (G1)
Major Collection:

Strain Information

Tln2
Name: talin 2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70549
VEGA: 9
Homologene: 56692
Npr1
Name: natriuretic peptide receptor 1
Synonyms: guanylyl cyclase-A, NPRA, GC-A, NPR-A
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18160
HGNC: HGNC:7943
Homologene: 37367
Cdon
Name: cell adhesion molecule-related/down-regulated by oncogenes
Synonyms: CAM-related/down-regulated by oncogenes, CDO
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 57810
Homologene: 22996
Trpc2
Name: transient receptor potential cation channel, subfamily C, member 2
Synonyms: trp2, TRPC2a, mTrp2, Trrp2, TRPC2b, 3010009O07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22064
Homologene: 135989
Zfp688
Name: zinc finger protein 688
Synonyms: 2810407K09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69234
Homologene: 17058
Psmd1
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
Synonyms: P112, S1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70247
HGNC: HGNC:9554
Homologene: 2100
Esyt2
Name: extended synaptotagmin-like protein 2
Synonyms: 2410017M09Rik, 2310058N22Rik, D12Ertd551e, 4921504I16Rik, Fam62b
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 52635
VEGA: 12
Homologene: 32699
Sin3a
Name: transcriptional regulator, SIN3A (yeast)
Synonyms: mSin3A, Sin3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20466
Homologene: 32124
Mbnl1
Name: muscleblind like splicing regulator 1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56758
HGNC: HGNC:6923
Homologene: 23186
Ncam1
Name: neural cell adhesion molecule 1
Synonyms: E-NCAM, NCAM-180, NCAM-140, CD56, NCAM-120, NCAM-1, NCAM
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17967
HGNC: HGNC:7656
Homologene: 40754
Muc16
Name: mucin 16
Synonyms: 1110008I14Rik, LOC385009, Gm21044
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73732
Homologene: 141193
Sorl1
Name: sortilin-related receptor, LDLR class A repeats-containing
Synonyms: Sorla, LR11, mSorLA, 2900010L19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20660
Homologene: 2336
Snrnp27
Name: small nuclear ribonucleoprotein 27 (U4/U6.U5)
Synonyms: 2610209M04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 66618
Homologene: 135794
Herpud2
Name: HERPUD family member 2
Synonyms: 5031400M07Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 80517
VEGA: 9
Homologene: 10756
2900026A02Rik
Name: RIKEN cDNA 2900026A02 gene
Synonyms: LOC231620, Gm449
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243219
Homologene: 129566
Tmco1
Name: transmembrane and coiled-coil domains 1
Synonyms: 1190006A08Rik, ESTM39, 4930403O06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68944
Homologene: 10384
Trmt44
Name: tRNA methyltransferase 44
Synonyms: 2310079F23Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 78890
Homologene: 12708
Vrk3
Name: vaccinia related kinase 3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101568
Homologene: 9509
G2e3
Name: G2/M-phase specific E3 ubiquitin ligase
Synonyms: D930034K21Rik, 6030408C04Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217558
Homologene: 32362
Zfp808
Name: zinc finger protein 808
Synonyms: Gm7036
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 630579
Homologene: 134631
Pgk2
Name: phosphoglycerate kinase 2
Synonyms: Pgk-2, Tcp-2, Tcp-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18663
VEGA: 17
HGNC: HGNC:8898
Homologene: 57138
Tex15
Name: testis expressed gene 15 meiosis and synapsis associated
Synonyms: 2210014E14Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 104271
Homologene: 12837
Tnfsf14
Name: tumor necrosis factor (ligand) superfamily, member 14
Synonyms: LIGHT, HVEM-L
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 50930
VEGA: 17
Homologene: 2822
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Galnt18
Name: polypeptide N-acetylgalactosaminyltransferase 18
Synonyms: Galntl4, 2900011G21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233733
Homologene: 18347
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Fcgbpl1
Name: Fc fragment of IgG binding protein like 1
Synonyms: 9530053A07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 319482
Homologene: 130055
Pcdh10
Name: protocadherin 10
Synonyms: 6430521D13Rik, OL-pc, 6430703F07Rik, Olpc
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18526
Homologene: 74967
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: OTTMUSG00000005786, LOC380698
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Wdr64
Name: WD repeat domain 64
Synonyms: 4930511H01Rik, 4930415O10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75820
Homologene: 51634
Or5b105
Name: olfactory receptor family 5 subfamily B member 105
Synonyms: MOR202-24, GA_x6K02T2RE5P-3430689-3429787, EG667271, Olfr1458
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 667271
HGNC: HGNC:8324
Hivep1
Name: human immunodeficiency virus type I enhancer binding protein 1
Synonyms: alphaA-CRYBP1, Cryabp1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110521
VEGA: 13
HGNC: HGNC:4920
Homologene: 1596
Mug1
Name: murinoglobulin 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17836
HGNC: HGNC:9750
Homologene: 136663
Cyp2j12
Name: cytochrome P450, family 2, subfamily j, polypeptide 12
Synonyms: Cyp2j12-ps, OTTMUSG00000007939
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242546
HGNC: HGNC:2634
Homologene: 133195
Sptlc3
Name: serine palmitoyltransferase, long chain base subunit 3
Synonyms: C130053K05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228677
Homologene: 105590
Cyp4a32
Name: cytochrome P450, family 4, subfamily a, polypeptide 32
Synonyms: OTTMUSG00000008689
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100040843
HGNC: HGNC:2642
Homologene: 128044
Dsc1
Name: desmocollin 1
Synonyms: Dsc1b, Dsc1a
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13505
VEGA: 18
HGNC: HGNC:3035
Homologene: 22761
Samsn1
Name: SAM domain, SH3 domain and nuclear localization signals, 1
Synonyms: 4930571B16Rik, Hacs1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67742
Homologene: 11148
Nfxl1
Name: nuclear transcription factor, X-box binding-like 1
Synonyms: D430033A06Rik, TCF9, 1700012H24Rik, LOC381696
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100978
Homologene: 26752
Cnr2
Name: cannabinoid receptor 2
Synonyms: CB2-R, CB2, cannabinoid receptor 2 (spleen)
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12802
HGNC: HGNC:2160
Homologene: 1389
Hoxd12
Name: homeobox D12
Synonyms: Hox-4.7, Hox-5.6
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15432
HGNC: HGNC:5135
Homologene: 7369
Ubox5
Name: U box domain containing 5
Synonyms: C330018L13Rik, 1500010O06Rik, UIP5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 140629
Homologene: 8972
Ajap1
Name: adherens junction associated protein 1
Synonyms: LOC230959
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230959
Homologene: 10312
Rab3a
Name: RAB3A, member RAS oncogene family
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 19339
HGNC: HGNC:9777
Homologene: 20629
Pinx1
Name: PIN2/TERF1 interacting, telomerase inhibitor 1
Synonyms: 2610028A01Rik, LPTS, 2210403I16Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 72400
VEGA: 14
Homologene: 134540
Gpt
Name: glutamic pyruvic transaminase, soluble
Synonyms: ALT, Gpt1, Gpt-1, 2310022B03Rik, 1300007J06Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 76282
VEGA: 15
HGNC: HGNC:4552
Homologene: 134231
Gm15922
Name: predicted gene 15922
Type: Gene
Species: Mouse
Chromosome: 7
Or7c70
Name: olfactory receptor family 7 subfamily C member 70
Synonyms: MOR142-2_p, GA_x6K02T2QGN0-2962025-2962987, Olfr1356, MOR142-1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258305
Homologene: 71958
Dipk1a
Name: divergent protein kinase domain 1A
Synonyms: Fam69a, 2900024C23Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67266
Homologene: 12104
Hps4
Name: HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
Synonyms: Hermansky-Pudlak syndrome 4, BLOC-3, C130020P05Rik, 2010205O06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 192232
Homologene: 11123
Malrd1
Name: MAM and LDL receptor class A domain containing 1
Synonyms: Gm13364, Gm13318, Diet1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 102635496
Homologene: 136214
Wfdc15a
Name: WAP four-disulfide core domain 15A
Synonyms: 1700049M11Rik, Wfdcl1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68221
Homologene: 77715
Gatb
Name: glutamyl-tRNA amidotransferase subunit B
Synonyms: Pet112l, Pet112, 9430026F02Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229487
HGNC: HGNC:8849
Homologene: 3357
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 86,133,768 bp (GRCm38)
  • C to T, chromosome 1 at 167,308,563 bp (GRCm38)
  • A to T, chromosome 1 at 175,726,458 bp (GRCm38)
  • C to T, chromosome 2 at 16,255,278 bp (GRCm38)
  • A to G, chromosome 2 at 41,122,981 bp (GRCm38)
  • T to A, chromosome 2 at 74,675,389 bp (GRCm38)
  • T to C, chromosome 2 at 130,600,245 bp (GRCm38)
  • G to T, chromosome 2 at 139,546,503 bp (GRCm38)
  • A to T, chromosome 2 at 164,199,712 bp (GRCm38)
  • T to C, chromosome 3 at 45,381,183 bp (GRCm38)
  • C to A, chromosome 3 at 60,603,747 bp (GRCm38)
  • C to T, chromosome 3 at 85,652,494 bp (GRCm38)
  • A to T, chromosome 3 at 90,458,672 bp (GRCm38)
  • A to G, chromosome 4 at 96,106,554 bp (GRCm38)
  • T to A, chromosome 4 at 115,621,438 bp (GRCm38)
  • A to G, chromosome 4 at 135,917,001 bp (GRCm38)
  • A to G, chromosome 4 at 153,432,504 bp (GRCm38)
  • T to C, chromosome 5 at 35,569,920 bp (GRCm38)
  • A to T, chromosome 5 at 72,524,108 bp (GRCm38)
  • A to T, chromosome 5 at 107,911,717 bp (GRCm38)
  • G to A, chromosome 5 at 112,378,039 bp (GRCm38)
  • T to A, chromosome 5 at 113,182,967 bp (GRCm38)
  • A to G, chromosome 6 at 86,676,202 bp (GRCm38)
  • A to G, chromosome 6 at 121,882,764 bp (GRCm38)
  • A to T, chromosome 7 at 3,739,235 bp (GRCm38)
  • C to T, chromosome 7 at 28,156,985 bp (GRCm38)
  • T to C, chromosome 7 at 44,775,486 bp (GRCm38)
  • T to C, chromosome 7 at 102,090,557 bp (GRCm38)
  • C to A, chromosome 7 at 111,472,064 bp (GRCm38)
  • A to G, chromosome 7 at 127,421,905 bp (GRCm38)
  • T to A, chromosome 8 at 33,575,115 bp (GRCm38)
  • C to T, chromosome 8 at 70,757,235 bp (GRCm38)
  • T to C, chromosome 9 at 18,641,036 bp (GRCm38)
  • T to C, chromosome 9 at 25,124,950 bp (GRCm38)
  • T to A, chromosome 9 at 35,488,979 bp (GRCm38)
  • A to C, chromosome 9 at 42,067,933 bp (GRCm38)
  • T to C, chromosome 9 at 49,544,797 bp (GRCm38)
  • C to T, chromosome 9 at 57,125,197 bp (GRCm38)
  • T to C, chromosome 9 at 67,321,931 bp (GRCm38)
  • T to C, chromosome 10 at 39,078,726 bp (GRCm38)
  • T to C, chromosome 10 at 78,847,319 bp (GRCm38)
  • G to A, chromosome 11 at 59,080,221 bp (GRCm38)
  • C to T, chromosome 12 at 51,357,145 bp (GRCm38)
  • G to A, chromosome 12 at 116,342,145 bp (GRCm38)
  • A to G, chromosome 13 at 42,164,237 bp (GRCm38)
  • A to T, chromosome 13 at 62,172,160 bp (GRCm38)
  • T to A, chromosome 14 at 63,872,328 bp (GRCm38)
  • G to A, chromosome 15 at 76,697,015 bp (GRCm38)
  • T to A, chromosome 16 at 75,876,545 bp (GRCm38)
  • T to A, chromosome 17 at 40,208,187 bp (GRCm38)
  • T to A, chromosome 17 at 57,194,020 bp (GRCm38)
  • T to A, chromosome 18 at 20,110,157 bp (GRCm38)
  • T to A, chromosome 19 at 13,103,224 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9330 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069142-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.