Strain Name:
C57BL/6J-MtgxR9402Btlr/Mmmh
Stock Number:
069206-MU
Citation ID:
RRID:MMRRC_069206-MU
Other Names:
R9402 (G1)
Major Collection:

Strain Information

Elp2
Name: elongator acetyltransferase complex subunit 2
Synonyms: StIP1, Stat3-interacting protein, Statip1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 58523
VEGA: 18
Homologene: 6019
Lamb3
Name: laminin, beta 3
Synonyms: nicein, 125kDa
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16780
HGNC: HGNC:6490
Homologene: 191
Nae1
Name: NEDD8 activating enzyme E1 subunit 1
Synonyms: Appbp1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234664
HGNC: HGNC:621
Homologene: 68370
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Magi1
Name: membrane associated guanylate kinase, WW and PDZ domain containing 1
Synonyms: Gukmi1, Baiap1, BAP1, WWP3, AIP3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14924
HGNC: HGNC:946
Homologene: 31257
Phf14
Name: PHD finger protein 14
Synonyms: 1110001C23Rik, 5730446A07Rik, 4932409F11Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 75725
Homologene: 8775
Prtg
Name: protogenin
Synonyms: Igdcc5, A230098A12Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235472
Homologene: 54453
Phf3
Name: PHD finger protein 3
Synonyms: AU020177, 2310061N19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 213109
HGNC: HGNC:8921
Homologene: 9040
Luzp1
Name: leucine zipper protein 1
Synonyms: 2700072H04Rik, Luzp
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269593
Homologene: 11545
Taf3
Name: TATA-box binding protein associated factor 3
Synonyms: 4933439M23Rik, mTAFII140
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 209361
Homologene: 35415
Fry
Name: FRY microtubule binding protein
Synonyms: 9330186A19Rik, cg003
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320365
Homologene: 113770
Exoc4
Name: exocyst complex component 4
Synonyms: Sec8, Sec8l1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20336
Homologene: 40654
Daam1
Name: dishevelled associated activator of morphogenesis 1
Synonyms: 2310028E21Rik, 1700066F09Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 208846
VEGA: 12
Homologene: 36635
Srbd1
Name: S1 RNA binding domain 1
Synonyms: D530025C17Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78586
VEGA: 17
Homologene: 9994
Trps1
Name: transcriptional repressor GATA binding 1
Synonyms: D15Ertd586e, trichorhinophalangeal syndrome I (human)
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 83925
Homologene: 8556
Atg2b
Name: autophagy related 2B
Synonyms: C030004M05Rik, 2410024A21Rik, C630028L02Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76559
VEGA: 12
Homologene: 9974
Krit1
Name: KRIT1, ankyrin repeat containing
Synonyms: 2010007K12Rik, Krit1B, Ccm1, Krit1, Krit1A, A630036P20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 79264
HGNC: HGNC:1573
Homologene: 12746
Nodal
Name: nodal growth differentiation factor
Synonyms: Tg.413d
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18119
HGNC: HGNC:7865
Homologene: 8417
Crim1
Name: cysteine rich transmembrane BMP regulator 1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 50766
VEGA: 17
HGNC: HGNC:2359
Homologene: 9510
Gas1
Name: growth arrest specific 1
Synonyms: Gas-1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14451
HGNC: HGNC:4165
Homologene: 1548
Mmadhc
Name: methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
Synonyms: 2010311D03Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 109129
Homologene: 9248
Htt
Name: huntingtin
Synonyms: HD, IT15, C430023I11Rik, htt, Hdh, huntingtin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 15194
HGNC: HGNC:4851
Homologene: 1593
Tcp1
Name: t-complex protein 1
Synonyms: c-cpn, p63, Tcp-1, Cct1, Tp63, CCT, Ccta, TRic
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21454
Homologene: 5656
Zfp748
Name: zinc finger protein 748
Synonyms: mszf54, KRAB-O, 2610014M12Rik, Zfp208
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 212276
Homologene: 134552
Inava
Name: innate immunity activator
Synonyms: 5730559C18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67313
Homologene: 10103
Pcdh17
Name: protocadherin 17
Synonyms: LOC219228, C030033F14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219228
VEGA: 14
Homologene: 8700
Cfap46
Name: cilia and flagella associated protein 46
Synonyms: Ttc40, 9330101J02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212124
Tns2
Name: tensin 2
Synonyms: nep, nph, Tenc1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 209039
VEGA: 15
Homologene: 37077
Nlgn2
Name: neuroligin 2
Synonyms: NLG2, NL2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216856
Homologene: 69317
Scn7a
Name: sodium channel, voltage-gated, type VII, alpha
Synonyms: Scn6a, Nax, NaG, Nav2, Nav2.3, 1110034K09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20272
Homologene: 55706
Ndst4
Name: N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
Synonyms: 4930439H17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 64580
Homologene: 11208
Nlrp9a
Name: NLR family, pyrin domain containing 9A
Synonyms: Nalp-theta, D7Ertd565e, Nalp9a
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233001
Homologene: 116072
Srp72
Name: signal recognition particle 72
Synonyms: 72kDa, 5730576P14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 66661
Homologene: 38254
Tubgcp6
Name: tubulin, gamma complex component 6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328580
Homologene: 32477
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC5, 2300002I04Rik, MUC9
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Taok2
Name: TAO kinase 2
Synonyms: TAO1, PSK1, 1110033K02Rik, MAP3K17, TAO2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381921
Homologene: 74531
Abca9
Name: ATP-binding cassette, sub-family A member 9
Synonyms: D630040K07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217262
HGNC: HGNC:39
Homologene: 33332
Bche
Name: butyrylcholinesterase
Synonyms: C730038G20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12038
HGNC: HGNC:983
Homologene: 20065
Steap1
Name: six transmembrane epithelial antigen of the prostate 1
Synonyms: 2410007B19Rik, Prss24
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70358
Homologene: 8256
Gpaa1
Name: GPI anchor attachment protein 1
Synonyms: mGAA1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 14731
HGNC: HGNC:4446
Homologene: 37852
Cyp4f39
Name: cytochrome P450, family 4, subfamily f, polypeptide 39
Synonyms: 4732474A20Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320997
VEGA: 17
Homologene: 69814
Pcdhb19
Name: protocadherin beta 19
Synonyms: Pcdhb11, PcdhbS
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93890
Homologene: 128411
Snx14
Name: sorting nexin 14
Synonyms: YR-14, C330035N22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244962
Homologene: 17823
Jmy
Name: junction-mediating and regulatory protein
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 57748
VEGA: 13
Homologene: 10955
Gbp10
Name: guanylate-binding protein 10
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 626578
Homologene: 128731
Cfap221
Name: cilia and flagella associated protein 221
Synonyms: Gm101, Pcdp1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226356
Homologene: 88578
Or4c12
Name: olfactory receptor family 4 subfamily C member 12
Synonyms: Olfr1259, GA_x6K02T2Q125-51376062-51375133, MOR232-9
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258338
Homologene: 128115
Tcerg1l
Name: transcription elongation regulator 1-like
Synonyms: 5730476P14Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70571
Homologene: 52165
Rtp3
Name: receptor transporter protein 3
Synonyms: Tmem7
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235636
Homologene: 135957
Vmn1r43
Name: vomeronasal 1 receptor 43
Synonyms: V1ra5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113847
Homologene: 130651
Fbxl7
Name: F-box and leucine-rich repeat protein 7
Synonyms: Fbl6, D230018M15Rik, FBL7
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 448987
VEGA: 15
Homologene: 69121
Klhl40
Name: kelch-like 40
Synonyms: 2310024D23Rik, Kbtbd5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72330
VEGA: 9
Homologene: 17571
Fbxl9
Name: F-box and leucine-rich repeat protein 9
Synonyms: A630024J02Rik, FBL9, Lrrc29
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234684
Homologene: 133339
Or52ab4
Name: olfactory receptor family 52 subfamily AB member 4
Synonyms: GA_x6K02T2PBJ9-6047402-6048349, MOR23-1, Olfr599
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258726
Homologene: 27244
Ugt1a2
Name: UDP glucuronosyltransferase 1 family, polypeptide A2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22236
Homologene: 86211
Orm1
Name: orosomucoid 1
Synonyms: Orm-1, Agp-2, Agp-1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18405
Homologene: 130632
Pigz
Name: phosphatidylinositol glycan anchor biosynthesis, class Z
Synonyms: F630022B06Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239827
Homologene: 130742
Or4a15
Name: olfactory receptor family 4 subfamily A member 15
Synonyms: GA_x6K02T2Q125-50805620-50804676, Olfr1234, MOR231-2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258975
Homologene: 128156
Or51a24
Name: olfactory receptor family 51 subfamily A member 24
Synonyms: GA_x6K02T2PBJ9-6819097-6818150, MOR13-5, Olfr645
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258247
Homologene: 66155
Scn3b
Name: sodium channel, voltage-gated, type III, beta
Synonyms: 4833414B02Rik, 1110001K16Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235281
Homologene: 10176
Hoxc13
Name: homeobox C13
Synonyms: N
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 15422
HGNC: HGNC:5125
Homologene: 7770
Gm14569
Name: predicted gene 14569
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 101055983
Homologene: 141085
Tas2r114
Name: taste receptor, type 2, member 114
Synonyms: T2R14, mt2r46, mGR14, Tas2r14
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387346
Homologene: 128355
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to A, chromosome 1 at 30,811,847 bp (GRCm38)
  • T to C, chromosome 1 at 88,200,962 bp (GRCm38)
  • T to A, chromosome 1 at 119,932,821 bp (GRCm38)
  • T to G, chromosome 1 at 136,227,610 bp (GRCm38)
  • C to A, chromosome 1 at 193,331,396 bp (GRCm38)
  • A to G, chromosome 2 at 9,951,112 bp (GRCm38)
  • A to T, chromosome 2 at 50,281,107 bp (GRCm38)
  • A to T, chromosome 2 at 66,680,112 bp (GRCm38)
  • C to A, chromosome 2 at 89,362,779 bp (GRCm38)
  • A to T, chromosome 2 at 89,943,940 bp (GRCm38)
  • T to C, chromosome 3 at 73,701,323 bp (GRCm38)
  • C to T, chromosome 3 at 125,724,736 bp (GRCm38)
  • C to A, chromosome 4 at 63,345,132 bp (GRCm38)
  • T to A, chromosome 4 at 136,543,182 bp (GRCm38)
  • T to C, chromosome 4 at 144,271,456 bp (GRCm38)
  • T to A, chromosome 5 at 3,822,210 bp (GRCm38)
  • T to A, chromosome 5 at 5,740,664 bp (GRCm38)
  • T to C, chromosome 5 at 34,848,980 bp (GRCm38)
  • T to A, chromosome 5 at 76,976,482 bp (GRCm38)
  • T to A, chromosome 5 at 105,233,997 bp (GRCm38)
  • G to A, chromosome 5 at 150,433,696 bp (GRCm38)
  • G to A, chromosome 5 at 150,436,853 bp (GRCm38)
  • A to G, chromosome 6 at 11,933,780 bp (GRCm38)
  • T to A, chromosome 6 at 33,476,143 bp (GRCm38)
  • G to A, chromosome 6 at 89,869,895 bp (GRCm38)
  • T to C, chromosome 6 at 94,283,297 bp (GRCm38)
  • C to T, chromosome 6 at 131,689,931 bp (GRCm38)
  • A to T, chromosome 7 at 26,570,605 bp (GRCm38)
  • T to C, chromosome 7 at 103,338,989 bp (GRCm38)
  • G to A, chromosome 7 at 104,084,403 bp (GRCm38)
  • T to C, chromosome 7 at 126,870,228 bp (GRCm38)
  • T to C, chromosome 7 at 138,209,822 bp (GRCm38)
  • G to T, chromosome 7 at 139,635,949 bp (GRCm38)
  • T to A, chromosome 7 at 141,845,414 bp (GRCm38)
  • A to G, chromosome 8 at 104,528,185 bp (GRCm38)
  • T to A, chromosome 8 at 105,323,356 bp (GRCm38)
  • A to T, chromosome 9 at 40,282,556 bp (GRCm38)
  • A to G, chromosome 9 at 72,911,971 bp (GRCm38)
  • C to T, chromosome 9 at 88,407,437 bp (GRCm38)
  • A to G, chromosome 9 at 110,985,963 bp (GRCm38)
  • A to G, chromosome 9 at 121,780,416 bp (GRCm38)
  • T to C, chromosome 10 at 61,423,600 bp (GRCm38)
  • A to G, chromosome 11 at 69,828,107 bp (GRCm38)
  • T to A, chromosome 11 at 110,158,328 bp (GRCm38)
  • A to G, chromosome 12 at 71,959,830 bp (GRCm38)
  • A to G, chromosome 12 at 105,648,423 bp (GRCm38)
  • T to A, chromosome 13 at 13,637,878 bp (GRCm38)
  • A to T, chromosome 13 at 60,176,202 bp (GRCm38)
  • A to G, chromosome 13 at 67,545,392 bp (GRCm38)
  • C to T, chromosome 13 at 93,499,170 bp (GRCm38)
  • T to C, chromosome 14 at 84,447,206 bp (GRCm38)
  • G to A, chromosome 15 at 26,552,503 bp (GRCm38)
  • A to T, chromosome 15 at 50,846,256 bp (GRCm38)
  • A to G, chromosome 15 at 76,332,218 bp (GRCm38)
  • A to G, chromosome 15 at 89,102,861 bp (GRCm38)
  • A to G, chromosome 15 at 102,113,188 bp (GRCm38)
  • C to A, chromosome 15 at 102,921,616 bp (GRCm38)
  • A to G, chromosome 16 at 31,945,369 bp (GRCm38)
  • T to A, chromosome 17 at 12,922,618 bp (GRCm38)
  • T to C, chromosome 17 at 32,491,209 bp (GRCm38)
  • CCGC to CC, chromosome 17 at 78,350,865 bp (GRCm38)
  • T to C, chromosome 17 at 86,099,277 bp (GRCm38)
  • A to T, chromosome 18 at 24,626,163 bp (GRCm38)
  • C to T, chromosome 18 at 37,499,479 bp (GRCm38)
  • G to A, chromosome X at 36,430,896 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9402 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069206-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.