Strain Name:
C57BL/6J-MtgxR9619Btlr/Mmmh
Stock Number:
069412-MU
Citation ID:
RRID:MMRRC_069412-MU
Other Names:
R9619 (G1)
Major Collection:

Strain Information

Foxq1
Name: forkhead box Q1
Synonyms: HFH-1, Hfh1l, sa, Hfh1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 15220
Homologene: 7359
Limch1
Name: LIM and calponin homology domains 1
Synonyms: 3732412D22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77569
Homologene: 18953
Slco1a5
Name: solute carrier organic anion transporter family, member 1a5
Synonyms: Oatp3, Slc21a7
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 108096
Homologene: 56603
Mfn1
Name: mitofusin 1
Synonyms: 6330416C07Rik, D3Ertd265e, HR2, 2310002F04Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67414
Homologene: 11481
Agrn
Name: agrin
Synonyms: NMF380, nmf380, Agrin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11603
HGNC: HGNC:329
Homologene: 27907
Kif20b
Name: kinesin family member 20B
Synonyms: N-6 kinesin, Mphosph1, magoo, 33cex, C330014J10Rik, Kif20b
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240641
VEGA: 19
HGNC: HGNC:7212
Homologene: 9418
Ect2
Name: ect2 oncogene
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 13605
HGNC: HGNC:3155
Homologene: 7298
Akap9
Name: A kinase anchor protein 9
Synonyms: G1-448-15, 5730481H23Rik, mei2-5, AKAP450, repro12
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Zwilch
Name: zwilch kinetochore protein
Synonyms: 2310031L18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68014
Homologene: 32381
Afdn
Name: afadin, adherens junction formation factor
Synonyms: 5033403D15Rik, Mllt4, Afadin, I-afadin, S-afadin, AF6
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17356
HGNC: HGNC:7137
Homologene: 21202
Cenpf
Name: centromere protein F
Synonyms: Lek1, mitosin, 6530404A22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Arfip1
Name: ADP-ribosylation factor interacting protein 1
Synonyms: Arfaptin, D3Ertd598e, 2310030I10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99889
Homologene: 8692
Wwc1
Name: WW, C2 and coiled-coil domain containing 1
Synonyms: Kibra
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 211652
Homologene: 69180
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: SYNE-1, A330049M09Rik, enaptin165, nesprin-1, C130039F11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Slc39a4
Name: solute carrier family 39 (zinc transporter), member 4
Synonyms: 1600025H15Rik, AWMS2, zip4
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72027
VEGA: 15
Homologene: 15638
Igfbp5
Name: insulin-like growth factor binding protein 5
Synonyms: IGFBP-5, IGFBP-5P
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16011
HGNC: HGNC:5474
Homologene: 56489
Rbm39
Name: RNA binding motif protein 39
Synonyms: 1500012C14Rik, 2310040E03Rik, Caper alpha, B330012G18Rik, caper, Rnpc2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 170791
Homologene: 136465
Treml1
Name: triggering receptor expressed on myeloid cells-like 1
Synonyms: 5430401J17Rik, TLT-1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71326
VEGA: 17
Homologene: 52257
Csgalnact1
Name: chondroitin sulfate N-acetylgalactosaminyltransferase 1
Synonyms: CSGalNAcT-1, 4732435N03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234356
Homologene: 23099
Rps10
Name: ribosomal protein S10
Synonyms: 2210402A09Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67097
Homologene: 788
Caap1
Name: caspase activity and apoptosis inhibitor 1
Synonyms: 5830433M19Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67770
Homologene: 32607
Cep152
Name: centrosomal protein 152
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99100
Homologene: 37159
Scrg1
Name: scrapie responsive gene 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20284
Homologene: 5269
Dnajc12
Name: DnaJ heat shock protein family (Hsp40) member C12
Synonyms: J domain protein 1, Jdp1, mJDP1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 30045
Homologene: 8492
Peg10
Name: paternally expressed 10
Synonyms: Rtl2, MEF3L, MyEF-3, Mar2, MyEF-3 like, Edr, HB-1, Mart2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 170676
Homologene: 116067
Idh2
Name: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Synonyms: IDPm, Idh-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269951
HGNC: HGNC:5383
Homologene: 37590
Lama2
Name: laminin, alpha 2
Synonyms: mer, merosin
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Efhc1
Name: EF-hand domain (C-terminal) containing 1
Synonyms: myoclonin1, mRib72-1, 1700029F22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71877
Homologene: 10003
Emp2
Name: epithelial membrane protein 2
Synonyms: Xmp
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13731
HGNC: HGNC:3334
Homologene: 1089
Dchs1
Name: dachsous cadherin related 1
Synonyms: 3110041P15Rik, C130033F22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233651
Homologene: 2771
Loxhd1
Name: lipoxygenase homology domains 1
Synonyms: 1700096C21Rik, sba
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240411
Pcnx4
Name: pecanex homolog 4
Synonyms: 1810048J11Rik, Pcnxl4
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 67708
VEGA: 12
Homologene: 23366
Trpv2
Name: transient receptor potential cation channel, subfamily V, member 2
Synonyms: VRL-1, Vrl1, OTRPC2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22368
Homologene: 7993
Ogfod2
Name: 2-oxoglutarate and iron-dependent oxygenase domain containing 2
Synonyms: 1300006G11Rik, 5730405M13Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 66627
Homologene: 32588
Ephb6
Name: Eph receptor B6
Synonyms: Cekl, Mep
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13848
HGNC: HGNC:3396
Homologene: 20940
Vmn2r61
Name: vomeronasal 2, receptor 61
Synonyms: EG637873, Gprc2a-rs2, Casr-rs2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 637873
Homologene: 129683
Vmn2r15
Name: vomeronasal 2, receptor 15
Synonyms: EG211223
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 211223
Homologene: 129606
Or2z8
Name: olfactory receptor family 2 subfamily Z member 8
Synonyms: GA_x6K02T2NUPS-191522-192466, MOR282-1, Olfr372
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 404315
Homologene: 17287
Zfp114
Name: zinc finger protein 114
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232966
Dsg1c
Name: desmoglein 1 gamma
Synonyms: Dsg6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 211924
HGNC: HGNC:3048
Ifi44
Name: interferon-induced protein 44
Synonyms: MTAP44, p44, A430056A10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99899
Homologene: 4683
Pcgf6
Name: polycomb group ring finger 6
Synonyms: Rnf134, MBLR, 4933407A11Rik, Mel18 and Bmi1-like RING finger protein
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 71041
VEGA: 19
Homologene: 12378
Arsk
Name: arylsulfatase K
Synonyms: 4833414G15Rik, 2810429K17Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 77041
Homologene: 12670
Klhl9
Name: kelch-like 9
Synonyms: C530050O22Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242521
Homologene: 23125
Fbln5
Name: fibulin 5
Synonyms: EVEC
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 23876
VEGA: 12
HGNC: HGNC:3602
Homologene: 38170
Zfp715
Name: zinc finger protein 715
Synonyms: mszf15, 2610041B18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69930
Homologene: 74591
Crx
Name: cone-rod homeobox
Synonyms: Crx1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12951
HGNC: HGNC:2383
Homologene: 467
Dyrk2
Name: dual-specificity tyrosine phosphorylation regulated kinase 2
Synonyms: 1810038L18Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 69181
VEGA: 10
HGNC: HGNC:3093
Homologene: 48437
Nexmif
Name: neurite extension and migration factor
Synonyms: Xpn, C77370
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 245555
Homologene: 19589
Tekt2
Name: tektin 2
Synonyms: tektin-t
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 24084
Homologene: 8043
Or5aq1b
Name: olfactory receptor family 5 subfamily AQ member 1B
Synonyms: Olfr1107, GA_x6K02T2Q125-48565383-48564445, MOR172-2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258841
Homologene: 131138
Ubqln3
Name: ubiquilin 3
Synonyms: 4933400K24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244178
Homologene: 9700
Dld
Name: dihydrolipoamide dehydrogenase
Synonyms: dihydrolipoyl dehydrogenase, branched chain alpha-keto acid dehydrogenase complex subunit E3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13382
VEGA: 12
HGNC: HGNC:2898
Homologene: 84
Prr16
Name: proline rich 16
Synonyms: 5430406M13Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 71373
VEGA: 18
Homologene: 41152
Dmrtb1
Name: DMRT-like family B with proline-rich C-terminal, 1
Synonyms: Dmrt6, Prp13
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56296
Homologene: 13207
Lad1
Name: ladinin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16763
HGNC: HGNC:6472
Homologene: 4059
Vopp1
Name: vesicular, overexpressed in cancer, prosurvival protein 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232023
Homologene: 12772
Igdcc3
Name: immunoglobulin superfamily, DCC subclass, member 3
Synonyms: Punc, 2810401C09Rik, WI-14920
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19289
VEGA: 9
HGNC: HGNC:9700
Homologene: 3590
Dpf1
Name: double PHD fingers 1
Synonyms: neuro-d4, Neud4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 29861
Homologene: 3415
Gm8237
Name: predicted gene 8237
Type: Gene
Species: Mouse
Chromosome: 14
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to A, chromosome 1 at 20,967,379 bp (GRCm38)
  • A to G, chromosome 1 at 72,862,384 bp (GRCm38)
  • G to T, chromosome 1 at 135,827,783 bp (GRCm38)
  • A to G, chromosome 1 at 189,653,768 bp (GRCm38)
  • T to A, chromosome 2 at 87,071,796 bp (GRCm38)
  • A to G, chromosome 2 at 125,594,907 bp (GRCm38)
  • A to T, chromosome 2 at 156,159,197 bp (GRCm38)
  • A to G, chromosome 3 at 27,146,877 bp (GRCm38)
  • A to G, chromosome 3 at 32,574,329 bp (GRCm38)
  • C to T, chromosome 3 at 84,527,774 bp (GRCm38)
  • T to C, chromosome 3 at 151,745,872 bp (GRCm38)
  • T to G, chromosome 4 at 88,676,525 bp (GRCm38)
  • T to C, chromosome 4 at 88,720,825 bp (GRCm38)
  • A to G, chromosome 4 at 94,556,481 bp (GRCm38)
  • G to T, chromosome 4 at 107,683,650 bp (GRCm38)
  • C to T, chromosome 4 at 126,323,651 bp (GRCm38)
  • A to G, chromosome 4 at 156,174,033 bp (GRCm38)
  • A to T, chromosome 5 at 4,044,833 bp (GRCm38)
  • T to C, chromosome 5 at 66,857,941 bp (GRCm38)
  • T to A, chromosome 5 at 109,292,756 bp (GRCm38)
  • G to A, chromosome 5 at 124,114,407 bp (GRCm38)
  • A to G, chromosome 6 at 4,755,316 bp (GRCm38)
  • T to C, chromosome 6 at 41,617,315 bp (GRCm38)
  • G to A, chromosome 6 at 57,754,632 bp (GRCm38)
  • T to C, chromosome 6 at 142,253,120 bp (GRCm38)
  • A to T, chromosome 7 at 15,868,260 bp (GRCm38)
  • A to G, chromosome 7 at 24,180,652 bp (GRCm38)
  • A to G, chromosome 7 at 29,313,193 bp (GRCm38)
  • A to G, chromosome 7 at 42,276,712 bp (GRCm38)
  • A to C, chromosome 7 at 43,299,680 bp (GRCm38)
  • TCCCAGG to T, chromosome 7 at 80,098,331 bp (GRCm38)
  • A to G, chromosome 7 at 104,141,846 bp (GRCm38)
  • C to T, chromosome 7 at 105,764,455 bp (GRCm38)
  • G to T, chromosome 8 at 57,474,329 bp (GRCm38)
  • A to G, chromosome 8 at 68,401,354 bp (GRCm38)
  • T to C, chromosome 8 at 72,057,761 bp (GRCm38)
  • A to G, chromosome 9 at 64,150,158 bp (GRCm38)
  • A to G, chromosome 9 at 65,185,270 bp (GRCm38)
  • A to C, chromosome 10 at 5,140,909 bp (GRCm38)
  • A to G, chromosome 10 at 27,188,286 bp (GRCm38)
  • G to A, chromosome 10 at 63,397,296 bp (GRCm38)
  • A to T, chromosome 10 at 118,860,387 bp (GRCm38)
  • A to G, chromosome 11 at 35,875,952 bp (GRCm38)
  • T to C, chromosome 11 at 62,589,736 bp (GRCm38)
  • A to T, chromosome 12 at 31,332,391 bp (GRCm38)
  • T to A, chromosome 12 at 72,575,508 bp (GRCm38)
  • A to C, chromosome 12 at 101,757,293 bp (GRCm38)
  • A to T, chromosome 13 at 31,559,597 bp (GRCm38)
  • T to C, chromosome 13 at 76,075,032 bp (GRCm38)
  • A to T, chromosome 14 at 5,863,637 bp (GRCm38)
  • T to A, chromosome 15 at 76,613,674 bp (GRCm38)
  • G to T, chromosome 16 at 10,284,556 bp (GRCm38)
  • T to C, chromosome 17 at 13,881,304 bp (GRCm38)
  • G to A, chromosome 17 at 27,630,485 bp (GRCm38)
  • T to A, chromosome 17 at 48,364,978 bp (GRCm38)
  • T to A, chromosome 18 at 20,283,442 bp (GRCm38)
  • T to A, chromosome 18 at 51,302,725 bp (GRCm38)
  • T to C, chromosome 18 at 77,356,175 bp (GRCm38)
  • A to C, chromosome 19 at 34,956,029 bp (GRCm38)
  • T to C, chromosome 19 at 47,048,822 bp (GRCm38)
  • C to T, chromosome X at 104,086,235 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9619 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069412-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.