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Strain Name:
C57BL/6J-MtgxR9619Btlr/Mmmh
Stock Number:
069412-MU
Citation ID:
RRID:MMRRC_069412-MU
Other Names:
R9619 (G1)
Major Collection:

Strain Information

Foxq1
Name: forkhead box Q1
Synonyms: HFH-1, Hfh1l, Hfh1, sa
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 15220
Homologene: 7359
Limch1
Name: LIM and calponin homology domains 1
Synonyms: 3732412D22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77569
Homologene: 18953
Slco1a5
Name: solute carrier organic anion transporter family, member 1a5
Synonyms: Oatp3, Slc21a7
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 108096
Homologene: 56603
Mfn1
Name: mitofusin 1
Synonyms: 6330416C07Rik, 2310002F04Rik, D3Ertd265e, HR2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67414
Homologene: 11481
Agrn
Name: agrin
Synonyms: NMF380, Agrin, nmf380
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11603
HGNC: HGNC:329
Homologene: 27907
Kif20b
Name: kinesin family member 20B
Synonyms: N-6 kinesin, C330014J10Rik, Kif20b, Mphosph1, 33cex, magoo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240641
VEGA: 19
HGNC: HGNC:7212
Homologene: 9418
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to A, chromosome 1 at 20,967,379 bp (GRCm38)
  • A to G, chromosome 1 at 72,862,384 bp (GRCm38)
  • G to T, chromosome 1 at 135,827,783 bp (GRCm38)
  • A to G, chromosome 1 at 189,653,768 bp (GRCm38)
  • T to A, chromosome 2 at 87,071,796 bp (GRCm38)
  • A to G, chromosome 2 at 125,594,907 bp (GRCm38)
  • A to T, chromosome 2 at 156,159,197 bp (GRCm38)
  • A to G, chromosome 3 at 27,146,877 bp (GRCm38)
  • A to G, chromosome 3 at 32,574,329 bp (GRCm38)
  • C to T, chromosome 3 at 84,527,774 bp (GRCm38)
  • T to C, chromosome 3 at 151,745,872 bp (GRCm38)
  • T to G, chromosome 4 at 88,676,525 bp (GRCm38)
  • T to C, chromosome 4 at 88,720,825 bp (GRCm38)
  • A to G, chromosome 4 at 94,556,481 bp (GRCm38)
  • G to T, chromosome 4 at 107,683,650 bp (GRCm38)
  • C to T, chromosome 4 at 126,323,651 bp (GRCm38)
  • A to G, chromosome 4 at 156,174,033 bp (GRCm38)
  • A to T, chromosome 5 at 4,044,833 bp (GRCm38)
  • T to C, chromosome 5 at 66,857,941 bp (GRCm38)
  • T to A, chromosome 5 at 109,292,756 bp (GRCm38)
  • G to A, chromosome 5 at 124,114,407 bp (GRCm38)
  • A to G, chromosome 6 at 4,755,316 bp (GRCm38)
  • T to C, chromosome 6 at 41,617,315 bp (GRCm38)
  • G to A, chromosome 6 at 57,754,632 bp (GRCm38)
  • T to C, chromosome 6 at 142,253,120 bp (GRCm38)
  • A to T, chromosome 7 at 15,868,260 bp (GRCm38)
  • A to G, chromosome 7 at 24,180,652 bp (GRCm38)
  • A to G, chromosome 7 at 29,313,193 bp (GRCm38)
  • A to G, chromosome 7 at 42,276,712 bp (GRCm38)
  • A to C, chromosome 7 at 43,299,680 bp (GRCm38)
  • TCCCAGG to T, chromosome 7 at 80,098,331 bp (GRCm38)
  • A to G, chromosome 7 at 104,141,846 bp (GRCm38)
  • C to T, chromosome 7 at 105,764,455 bp (GRCm38)
  • G to T, chromosome 8 at 57,474,329 bp (GRCm38)
  • A to G, chromosome 8 at 68,401,354 bp (GRCm38)
  • T to C, chromosome 8 at 72,057,761 bp (GRCm38)
  • A to G, chromosome 9 at 64,150,158 bp (GRCm38)
  • A to G, chromosome 9 at 65,185,270 bp (GRCm38)
  • A to C, chromosome 10 at 5,140,909 bp (GRCm38)
  • A to G, chromosome 10 at 27,188,286 bp (GRCm38)
  • G to A, chromosome 10 at 63,397,296 bp (GRCm38)
  • A to T, chromosome 10 at 118,860,387 bp (GRCm38)
  • A to G, chromosome 11 at 35,875,952 bp (GRCm38)
  • T to C, chromosome 11 at 62,589,736 bp (GRCm38)
  • A to T, chromosome 12 at 31,332,391 bp (GRCm38)
  • T to A, chromosome 12 at 72,575,508 bp (GRCm38)
  • A to C, chromosome 12 at 101,757,293 bp (GRCm38)
  • A to T, chromosome 13 at 31,559,597 bp (GRCm38)
  • T to C, chromosome 13 at 76,075,032 bp (GRCm38)
  • A to T, chromosome 14 at 5,863,637 bp (GRCm38)
  • T to A, chromosome 15 at 76,613,674 bp (GRCm38)
  • G to T, chromosome 16 at 10,284,556 bp (GRCm38)
  • T to C, chromosome 17 at 13,881,304 bp (GRCm38)
  • G to A, chromosome 17 at 27,630,485 bp (GRCm38)
  • T to A, chromosome 17 at 48,364,978 bp (GRCm38)
  • T to A, chromosome 18 at 20,283,442 bp (GRCm38)
  • T to A, chromosome 18 at 51,302,725 bp (GRCm38)
  • T to C, chromosome 18 at 77,356,175 bp (GRCm38)
  • A to C, chromosome 19 at 34,956,029 bp (GRCm38)
  • T to C, chromosome 19 at 47,048,822 bp (GRCm38)
  • C to T, chromosome X at 104,086,235 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9619 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069412-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.