Strain Name:
C57BL/6J-MtgxR9743Btlr/Mmmh
Stock Number:
069989-MU
Citation ID:
RRID:MMRRC_069989-MU
Other Names:
R9743 (G1)
Major Collection:

Strain Information

Ank2
Name: ankyrin 2, brain
Synonyms: Ankyrin-2, ankyrin B, Ank-2, Ankyrin-B, Gm4392
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Mkks
Name: McKusick-Kaufman syndrome
Synonyms: Bbs6, 1300013E18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 59030
HGNC: HGNC:7108
Homologene: 10318
Gria4
Name: glutamate receptor, ionotropic, AMPA4 (alpha 4)
Synonyms: Glur-4, Gluralpha4, Glur4, spkw1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14802
HGNC: HGNC:4574
Homologene: 20227
Ercc6
Name: excision repair cross-complementing rodent repair deficiency, complementation group 6
Synonyms: CS group B correcting gene, C130058G22Rik, CSB
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 319955
VEGA: 14
HGNC: HGNC:3438
Homologene: 133552
Taf4
Name: TATA-box binding protein associated factor 4
Synonyms: TAFII130, Taf2c1, Taf4a, TAFII135
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228980
Homologene: 55723
Abl1
Name: c-abl oncogene 1, non-receptor tyrosine kinase
Synonyms: c-Abl, E430008G22Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11350
HGNC: HGNC:76
Homologene: 3783
Tg
Name: thyroglobulin
Synonyms: Tgn
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 21819
Homologene: 2430
Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13078
VEGA: 17
HGNC: HGNC:2597
Homologene: 68035
Supt16
Name: SPT16, facilitates chromatin remodeling subunit
Synonyms: Spt16, Cdc68, Fact140, Supt16h
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 114741
VEGA: 14
Homologene: 5207
Dgkd
Name: diacylglycerol kinase, delta
Synonyms: DGKdelta, dgkd-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227333
HGNC: HGNC:2851
Homologene: 100054
Pdik1l
Name: PDLIM1 interacting kinase 1 like
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230809
Homologene: 36977
B3galt2
Name: UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 26878
HGNC: HGNC:917
Homologene: 74512
Slf2
Name: SMC5-SMC6 complex localization factor 2
Synonyms: Fam178a, 6030443O07Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226151
VEGA: 19
Homologene: 23077
Pigr
Name: polymeric immunoglobulin receptor
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18703
HGNC: HGNC:8968
Homologene: 1984
Aspn
Name: asporin
Synonyms: PLAP-1, 4631401G09Rik, SLRR1C
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66695
VEGA: 13
Homologene: 32357
Fbxo7
Name: F-box protein 7
Synonyms: 2410015K21Rik, A230052G17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 69754
Homologene: 8136
Tas1r3
Name: taste receptor, type 1, member 3
Synonyms: T1r3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 83771
Homologene: 12890
Adamts13
Name: ADAM metallopeptidase with thrombospondin type 1 motif 13
Synonyms: LOC279028, vWF-CP mRNA for von Willebrand factor-cleaving
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 279028
HGNC: HGNC:1366
Homologene: 16372
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Ptprq
Name: protein tyrosine phosphatase receptor type Q
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237523
HGNC: HGNC:9679
Homologene: 83557
Vmn2r103
Name: vomeronasal 2, receptor 103
Synonyms: EG627636
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627636
Homologene: 115024
Emilin2
Name: elastin microfibril interfacer 2
Synonyms: basilin, FOAP-10
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 246707
VEGA: 17
Homologene: 36483
Olfm2
Name: olfactomedin 2
Synonyms: A030009A06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244723
VEGA: 9
Homologene: 14380
D130043K22Rik
Name: RIKEN cDNA D130043K22 gene
Synonyms: Kiaa0319
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 210108
Homologene: 8878
Brd10
Name: bromodomain containing 10
Synonyms: 9930021J03Rik, Gm9832
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240613
Homologene: 19046
Hfm1
Name: HFM1, ATP-dependent DNA helicase homolog
Synonyms: LOC381663, A330009G12Rik, Sec63d1, Mer3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330149
Homologene: 87103
Slc22a21
Name: solute carrier family 22 (organic cation transporter), member 21
Synonyms: Octn3, Slc22a9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56517
Homologene: 137336
Unc5d
Name: unc-5 netrin receptor D
Synonyms: Unc5h4, D930029E11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 210801
Homologene: 15450
AI661453
Name: expressed sequence AI661453
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224833
Homologene: 138294
Pdzrn3
Name: PDZ domain containing RING finger 3
Synonyms: semaphorin cytoplasmic domain-associated protein 3A, Semcap3, LNX3, 1110020C07Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 55983
Homologene: 10328
Or2a25
Name: olfactory receptor family 2 subfamily A member 25
Synonyms: GA_x6K02T2P3E9-4647978-4647046, MOR261-1, Olfr447
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258990
Homologene: 17457
Col5a1
Name: collagen, type V, alpha 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12831
HGNC: HGNC:2209
Homologene: 55434
Armc2
Name: armadillo repeat containing 2
Synonyms: 2610018I05Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 213402
Homologene: 41848
Vmn2r52
Name: vomeronasal 2, receptor 52
Synonyms: EG384534
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 384534
Homologene: 129605
Tsr3
Name: TSR3 20S rRNA accumulation
Synonyms: 1110014B11Rik, 0610007P22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68327
VEGA: 17
Homologene: 6922
Or7h8
Name: olfactory receptor family 7 subfamily H member 8
Synonyms: GA_x6K02T2PVTD-13952555-13953490, MOR141-2, Olfr871
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258905
Homologene: 138319
Vmn2r20
Name: vomeronasal 2, receptor 20
Synonyms: EG667180
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 667180
Homologene: 84037
Fam149b
Name: family with sequence similarity 149, member B
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105428
VEGA: 14
Homologene: 67023
Setdb2
Name: SET domain, bifurcated 2
Synonyms: KMT1F, LOC239122
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239122
Homologene: 12903
Or2a51
Name: olfactory receptor family 2 subfamily A member 51
Synonyms: GA_x6K02T2P3E9-4356476-4355535, Olfr435, MOR261-5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258647
Homologene: 110586
Pex13
Name: peroxisomal biogenesis factor 13
Synonyms: 2610008O20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72129
HGNC: HGNC:8855
Homologene: 1967
Zfp760
Name: zinc finger protein 760
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240034
VEGA: 17
Ccl3
Name: C-C motif chemokine ligand 3
Synonyms: CCL3, macrophage inflammatory protein-1alpha, MIP1-alpha, MIP1-(a), G0S19-1, Mip1a, LD78alpha, MIP-1alpha, Scya3, MIP-1 alpha
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20302
Homologene: 2242
Tmc7
Name: transmembrane channel-like gene family 7
Synonyms: 1700030H01Rik, C630024K23Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 209760
Homologene: 36424
Rnase11
Name: ribonuclease, RNase A family, 11 (non-active)
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 497113
Homologene: 17054
Or5aq7
Name: olfactory receptor family 5 subfamily AQ member 7
Synonyms: GA_x6K02T2N869-1820-882, Olfr259, MOR172-3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258766
Homologene: 106833
Tor3a
Name: torsin family 3, member A
Synonyms: Adir
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 30935
Homologene: 23359
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 87,934,128 bp (GRCm38)
  • G to A, chromosome 1 at 130,841,803 bp (GRCm38)
  • T to C, chromosome 1 at 143,647,109 bp (GRCm38)
  • T to C, chromosome 1 at 156,673,533 bp (GRCm38)
  • T to C, chromosome 2 at 26,996,800 bp (GRCm38)
  • G to A, chromosome 2 at 27,005,479 bp (GRCm38)
  • C to T, chromosome 2 at 27,974,493 bp (GRCm38)
  • A to G, chromosome 2 at 31,797,704 bp (GRCm38)
  • A to G, chromosome 2 at 87,107,496 bp (GRCm38)
  • T to C, chromosome 2 at 136,881,072 bp (GRCm38)
  • C to T, chromosome 2 at 179,939,799 bp (GRCm38)
  • A to T, chromosome 3 at 126,940,145 bp (GRCm38)
  • T to C, chromosome 4 at 88,676,693 bp (GRCm38)
  • A to T, chromosome 4 at 134,284,504 bp (GRCm38)
  • G to A, chromosome 4 at 155,860,799 bp (GRCm38)
  • T to C, chromosome 5 at 106,874,259 bp (GRCm38)
  • G to A, chromosome 6 at 42,911,901 bp (GRCm38)
  • A to G, chromosome 6 at 43,202,295 bp (GRCm38)
  • C to A, chromosome 6 at 101,377,717 bp (GRCm38)
  • A to T, chromosome 6 at 123,396,410 bp (GRCm38)
  • T to C, chromosome 7 at 10,170,679 bp (GRCm38)
  • C to A, chromosome 7 at 118,551,229 bp (GRCm38)
  • T to C, chromosome 8 at 28,719,773 bp (GRCm38)
  • T to G, chromosome 9 at 4,464,457 bp (GRCm38)
  • A to G, chromosome 9 at 20,212,544 bp (GRCm38)
  • T to C, chromosome 9 at 20,668,489 bp (GRCm38)
  • T to G, chromosome 10 at 41,922,602 bp (GRCm38)
  • T to C, chromosome 10 at 86,047,909 bp (GRCm38)
  • T to A, chromosome 10 at 107,685,121 bp (GRCm38)
  • A to T, chromosome 11 at 23,656,119 bp (GRCm38)
  • A to G, chromosome 11 at 53,951,749 bp (GRCm38)
  • A to G, chromosome 11 at 77,832,478 bp (GRCm38)
  • T to C, chromosome 11 at 83,648,602 bp (GRCm38)
  • T to C, chromosome 13 at 13,634,738 bp (GRCm38)
  • C to T, chromosome 13 at 24,872,316 bp (GRCm38)
  • A to G, chromosome 13 at 49,551,674 bp (GRCm38)
  • A to G, chromosome 14 at 20,363,343 bp (GRCm38)
  • T to G, chromosome 14 at 32,576,986 bp (GRCm38)
  • T to A, chromosome 14 at 51,049,913 bp (GRCm38)
  • T to C, chromosome 14 at 52,171,482 bp (GRCm38)
  • T to C, chromosome 14 at 59,413,553 bp (GRCm38)
  • G to A, chromosome 15 at 66,689,990 bp (GRCm38)
  • T to C, chromosome 16 at 32,780,824 bp (GRCm38)
  • T to A, chromosome 17 at 19,812,213 bp (GRCm38)
  • T to A, chromosome 17 at 21,723,357 bp (GRCm38)
  • T to C, chromosome 17 at 25,241,700 bp (GRCm38)
  • T to A, chromosome 17 at 47,469,315 bp (GRCm38)
  • T to C, chromosome 17 at 71,273,872 bp (GRCm38)
  • T to A, chromosome 17 at 79,710,379 bp (GRCm38)
  • A to C, chromosome 19 at 29,716,861 bp (GRCm38)
  • T to C, chromosome 19 at 44,942,133 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9743 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069989-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.