Strain Name:
C57BL/6J-MtgxR0114Btlr/Mmmh
Stock Number:
038400-MU
Citation ID:
RRID:MMRRC_038400-MU
Other Names:
R0114 (G1), C57BL/6J-MtgxR0114Btlr
Major Collection:

Strain Information

Limch1
Name: LIM and calponin homology domains 1
Synonyms: 3732412D22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77569
Homologene: 18953
Rad54l2
Name: RAD54 like 2 (S. cerevisiae)
Synonyms: Srisnf2l, G630026H09Rik, Arip4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 81000
Homologene: 56698
Utp23
Name: UTP23 small subunit processome component
Synonyms: D530033C11Rik, 1700010I21Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 78581
Homologene: 41789
Lgi3
Name: leucine-rich repeat LGI family, member 3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 213469
VEGA: 14
Homologene: 16406
Sema4b
Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
Synonyms: Semac, SemC
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20352
Homologene: 8426
Tfr2
Name: transferrin receptor 2
Synonyms: Trfr2, Tfr2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 50765
Homologene: 2428
Usp28
Name: ubiquitin specific peptidase 28
Synonyms: 9830148O20Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235323
VEGA: 9
Homologene: 10840
Phf3
Name: PHD finger protein 3
Synonyms: AU020177, 2310061N19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 213109
HGNC: HGNC:8921
Homologene: 9040
Ckap5
Name: cytoskeleton associated protein 5
Synonyms: 3110043H24Rik, D730027C18Rik, 4930432B04Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75786
Homologene: 8844
Naa15
Name: N(alpha)-acetyltransferase 15, NatA auxiliary subunit
Synonyms: Tbdn-1, ASTBDN, Narg1, mNAT1, 5730450D16Rik, tubedown
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74838
Homologene: 14211
Anln
Name: anillin, actin binding protein
Synonyms: 1110037A17Rik, Scraps, 2900037I21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68743
VEGA: 9
Homologene: 41281
Prpf4b
Name: pre-mRNA processing factor 4B
Synonyms: Prp4, Prpk, Prp4k
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 19134
VEGA: 13
Homologene: 134085
Xrn2
Name: 5'-3' exoribonuclease 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 24128
Homologene: 6927
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F37S1, D7H15F32S1, rjs, jdf2, D15F32S1h
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Opa1
Name: OPA1, mitochondrial dynamin like GTPase
Synonyms: 1200011N24Rik, lilr3, optic atrophy 1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74143
HGNC: HGNC:8140
Homologene: 14618
Slc25a17
Name: solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
Synonyms: 34kDa, PMP34
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20524
VEGA: 15
Homologene: 4637
Gnpat
Name: glyceronephosphate O-acyltransferase
Synonyms: D1Ertd819e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14712
HGNC: HGNC:4416
Homologene: 40716
Nvl
Name: nuclear VCP-like
Synonyms: 1200009I24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67459
HGNC: HGNC:8070
Homologene: 1902
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: 2810449H11Rik, D130015N03Rik, tbl
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Gabpb1
Name: GA repeat binding protein, beta 1
Synonyms: E4Tf1B, GABPB1-2, NRF2B1, E4TF1, NRF2B2, GABPB1-1, BABPB2, E4TF1-53, E4TF1-47
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14391
HGNC: HGNC:4074
Homologene: 7723
Bmpr2
Name: bone morphogenetic protein receptor type 2
Synonyms: BMPR-II, BMPRII, BMP-2, 2610024H22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12168
HGNC: HGNC:1078
Homologene: 929
Cftr
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12638
HGNC: HGNC:1884
Homologene: 55465
Lipc
Name: lipase, hepatic
Synonyms: HL, Hpl
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 15450
VEGA: 9
HGNC: HGNC:6619
Homologene: 199
Polr2b
Name: polymerase (RNA) II (DNA directed) polypeptide B
Synonyms: RPB2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231329
HGNC: HGNC:9188
Homologene: 722
Cand1
Name: cullin associated and neddylation disassociated 1
Synonyms: D10Ertd516e, 2310038O07Rik, 6330512O03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71902
Homologene: 10202
Alms1
Name: ALMS1, centrosome and basal body associated
Synonyms: Alstrom syndrome 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 236266
HGNC: HGNC:428
Homologene: 49406
Sema6a
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Synonyms: A730020P05Rik, sema, Sema6A-1, VIa, Semaq
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 20358
Homologene: 32426
Fam151a
Name: family with sequence simliarity 151, member A
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230579
Homologene: 17143
Gmds
Name: GDP-mannose 4, 6-dehydratase
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218138
HGNC: HGNC:4369
Homologene: 75968
Ino80
Name: INO80 complex subunit
Synonyms: 2310079N15Rik, INO80, Inoc1, 4632409L19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68142
Homologene: 75070
Fnip1
Name: folliculin interacting protein 1
Synonyms: A730024A03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216742
Homologene: 28173
Thoc6
Name: THO complex 6
Synonyms: Wdr58, F830014G06Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 386612
Homologene: 11533
Tmtc1
Name: transmembrane and tetratricopeptide repeat containing 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387314
Homologene: 65299
Ppp2r5b
Name: protein phosphatase 2, regulatory subunit B', beta
Synonyms: B'beta
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225849
HGNC: HGNC:9310
Homologene: 38157
Prg2
Name: proteoglycan 2, bone marrow
Synonyms: EMBP, mMBP-1, mMBP
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19074
HGNC: HGNC:9362
Homologene: 2044
Itga11
Name: integrin alpha 11
Synonyms: 4732459H24Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 319480
HGNC: HGNC:6136
Homologene: 8151
Lama2
Name: laminin, alpha 2
Synonyms: merosin, mer
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Rusc2
Name: RUN and SH3 domain containing 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100213
Homologene: 18967
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Ip3r2, Itpr5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 672511
Homologene: 45439
Mybpc3
Name: myosin binding protein C, cardiac
Synonyms: cardiac C-protein
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17868
HGNC: HGNC:7551
Homologene: 215
Nckap1l
Name: NCK associated protein 1 like
Synonyms: Hem1, 4930568P13Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105855
VEGA: 15
HGNC: HGNC:4862
Homologene: 3901
Arnt2
Name: aryl hydrocarbon receptor nuclear translocator 2
Synonyms: bHLHe1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11864
Homologene: 7230
Vwa3a
Name: von Willebrand factor A domain containing 3A
Synonyms: E030013G06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233813
Homologene: 18607
Nlrp9b
Name: NLR family, pyrin domain containing 9B
Synonyms: Nalp9b, Nalp-delta
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243874
Homologene: 18530
Specc1
Name: sperm antigen with calponin homology and coiled-coil domains 1
Synonyms: Cytsb, 2810012G08Rik, B230396K10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 432572
Homologene: 45157
Arhgef10l
Name: Rho guanine nucleotide exchange factor 10-like
Synonyms: 2810441C07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 72754
Homologene: 10017
Ppp1r16a
Name: protein phosphatase 1, regulatory subunit 16A
Synonyms: Mypt3, 2900084E10Rik, R75527
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 73062
Homologene: 13161
Mfsd13a
Name: major facilitator superfamily domain containing 13a
Synonyms: 4930538D17Rik, Tmem180, 4930449A08Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 75146
Homologene: 12592
Myo5b
Name: myosin VB
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17919
HGNC: HGNC:7603
Homologene: 49481
Pcnx1
Name: pecanex 1
Synonyms: Pcnx, 3526401J03Rik, 2900024E21Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 54604
VEGA: 12
Homologene: 40997
Gnptab
Name: N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
Synonyms: EG432486
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 432486
Homologene: 32576
Dpp10
Name: dipeptidylpeptidase 10
Synonyms: DPRP3, 6430601K09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269109
Homologene: 41400
Fes
Name: feline sarcoma oncogene
Synonyms: c-fes
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14159
HGNC: HGNC:3657
Homologene: 37563
Akt3
Name: thymoma viral proto-oncogene 3
Synonyms: Nmf350, D930002M15Rik, PKB gamma
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 23797
HGNC: HGNC:393
Homologene: 55904
Slc13a3
Name: solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
Synonyms: NaDC-3, NaDC3, SDCT2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 114644
Homologene: 11266
Atp9a
Name: ATPase, class II, type 9A
Synonyms: Class II, IIa
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11981
Homologene: 69194
Dnai1
Name: dynein axonemal intermediate chain 1
Synonyms: 1110066F04Rik, b2b1526Clo, Dnaic1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68922
HGNC: HGNC:2954
Homologene: 8122
Tex48
Name: testis expressed 48
Synonyms: 1700018C11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 75524
Homologene: 87066
Vwa5b1
Name: von Willebrand factor A domain containing 5B1
Synonyms: 4931403E03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 75718
Homologene: 19431
Tnfrsf8
Name: tumor necrosis factor receptor superfamily, member 8
Synonyms: CD30
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21941
Homologene: 949
Mug2
Name: murinoglobulin 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17837
HGNC: HGNC:9750
Homologene: 136663
Ppfibp1
Name: PTPRF interacting protein, binding protein 1 (liprin beta 1)
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67533
HGNC: HGNC:9249
Homologene: 2685
Or52b4i
Name: olfactory receptor family 52 subfamily B member 4I
Synonyms: MOR31-13, GA_x6K02T2PBJ9-5263046-5263989, Olfr548
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258229
Tgfb1i1
Name: transforming growth factor beta 1 induced transcript 1
Synonyms: TSC-5, ARA55, hic-5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21804
Homologene: 7572
Ano9
Name: anoctamin 9
Synonyms: Trp53i5, Tp53i5, 5430425C04Rik, Tmem16j
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71345
Homologene: 67083
Gpi-ps
Name: glucose-6-phosphate isomerase, pseudogene
Synonyms: LOC233995, Gm1840
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 669429
Fanca
Name: Fanconi anemia, complementation group A
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14087
HGNC: HGNC:3582
Homologene: 108
2310057J18Rik
Name: RIKEN cDNA 2310057J18 gene
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67719
Homologene: 82613
Or6c211
Name: olfactory receptor family 6 subfamily C member 211
Synonyms: GA_x6K02T2PULF-11349138-11348182, Olfr801, MOR110-10
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258282
Homologene: 138306
Nprl3
Name: nitrogen permease regulator-like 3
Synonyms: HS-40, Mare, m(alpha)RE, -14 gene, Phg, HS-26, Prox1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17168
Homologene: 8091
Or1x2
Name: olfactory receptor family 1 subfamily X member 2
Synonyms: GA_x6K02T2QP88-4411197-4410256, Olfr54, MOR126-1, F3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18354
Homologene: 115479
Phykpl
Name: 5-phosphohydroxy-L-lysine phospholyase
Synonyms: 2900006B13Rik, Agxt2l2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72947
Homologene: 75268
4933427D14Rik
Name: RIKEN cDNA 4933427D14 gene
Synonyms: Gm43951
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74477
Homologene: 8874
Zfp735
Name: zinc finger protein 735
Synonyms: 1700012C15Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76390
Homologene: 88945
Ppm1d
Name: protein phosphatase 1D magnesium-dependent, delta isoform
Synonyms: Wip1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 53892
HGNC: HGNC:9277
Homologene: 31185
Ppp4r4
Name: protein phosphatase 4, regulatory subunit 4
Synonyms: 8430415E04Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74521
Homologene: 12571
Lrit2
Name: leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
Synonyms: A930010E21Rik, Lrrc22
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239038
VEGA: 14
Homologene: 18292
Adamts1
Name: ADAM metallopeptidase with thrombospondin type 1 motif 1
Synonyms: METH-1, ADAM-TS1, METH1, ADAMTS-1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 11504
HGNC: HGNC:217
Homologene: 21381
Or14j3
Name: olfactory receptor family 14 subfamily J member 3
Synonyms: Olfr114, GA_x6K02T2PSCP-2049802-2048870, MOR218-10
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258284
Homologene: 133642
Cyp26c1
Name: cytochrome P450, family 26, subfamily c, polypeptide 1
Synonyms: EG546726
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 546726
VEGA: 19
Homologene: 28089
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 30,805,443 bp
  • G to T, chromosome 1 at 59,815,340 bp
  • T to C, chromosome 1 at 123,486,092 bp
  • T to C, chromosome 1 at 177,067,251 bp
  • A to G, chromosome 1 at 181,120,391 bp
  • G to C, chromosome 2 at 76,707,093 bp
  • A to G, chromosome 2 at 84,983,456 bp
  • A to G, chromosome 2 at 91,124,494 bp
  • A to T, chromosome 2 at 91,620,112 bp
  • G to A, chromosome 2 at 119,382,960 bp
  • A to G, chromosome 2 at 126,653,574 bp
  • A to T, chromosome 2 at 147,029,779 bp
  • A to G, chromosome 2 at 165,424,581 bp
  • G to T, chromosome 2 at 168,710,856 bp
  • T to C, chromosome 3 at 51,448,438 bp
  • T to C, chromosome 4 at 41,605,686 bp
  • G to T, chromosome 4 at 43,422,055 bp
  • T to A, chromosome 4 at 63,608,459 bp
  • A to T, chromosome 4 at 106,734,004 bp
  • C to A, chromosome 4 at 138,608,858 bp
  • T to C, chromosome 4 at 140,583,883 bp
  • T to C, chromosome 4 at 145,288,047 bp
  • C to T, chromosome 5 at 67,036,084 bp
  • T to A, chromosome 5 at 77,343,263 bp
  • T to C, chromosome 5 at 137,577,465 bp
  • A to T, chromosome 6 at 18,282,448 bp
  • T to C, chromosome 6 at 85,619,803 bp
  • A to G, chromosome 6 at 122,040,648 bp
  • A to G, chromosome 6 at 146,312,879 bp
  • A to G, chromosome 6 at 146,998,233 bp
  • G to A, chromosome 6 at 148,412,830 bp
  • A to G, chromosome 7 at 20,024,056 bp
  • T to C, chromosome 7 at 56,153,774 bp
  • A to G, chromosome 7 at 80,219,078 bp
  • A to G, chromosome 7 at 80,378,035 bp
  • G to A, chromosome 7 at 84,347,530 bp
  • A to T, chromosome 7 at 102,542,731 bp
  • A to G, chromosome 7 at 120,775,380 bp
  • A to C, chromosome 7 at 128,249,494 bp
  • A to T, chromosome 7 at 141,103,239 bp
  • A to G, chromosome 8 at 5,640,359 bp
  • A to T, chromosome 8 at 123,288,491 bp
  • T to G, chromosome 8 at 124,883,357 bp
  • A to T, chromosome 9 at 22,353,346 bp
  • C to A, chromosome 9 at 49,039,023 bp
  • T to G, chromosome 9 at 62,735,293 bp
  • T to C, chromosome 9 at 62,760,302 bp
  • T to A, chromosome 9 at 66,461,846 bp
  • T to C, chromosome 9 at 70,803,781 bp
  • T to A, chromosome 9 at 88,584,160 bp
  • T to C, chromosome 9 at 106,713,455 bp
  • C to A, chromosome 10 at 26,993,068 bp
  • T to C, chromosome 10 at 28,985,982 bp
  • C to A, chromosome 10 at 88,433,400 bp
  • T to C, chromosome 10 at 119,216,522 bp
  • T to A, chromosome 10 at 129,669,598 bp
  • T to A, chromosome 11 at 32,239,784 bp
  • G to A, chromosome 11 at 51,027,604 bp
  • G to A, chromosome 11 at 51,586,653 bp
  • C to T, chromosome 11 at 54,487,801 bp
  • A to T, chromosome 11 at 62,146,313 bp
  • T to C, chromosome 11 at 72,195,799 bp
  • A to T, chromosome 11 at 73,710,662 bp
  • G to A, chromosome 11 at 85,326,905 bp
  • G to T, chromosome 11 at 119,414,587 bp
  • T to C, chromosome 12 at 81,996,095 bp
  • T to A, chromosome 12 at 103,576,374 bp
  • A to T, chromosome 13 at 32,227,281 bp
  • G to A, chromosome 13 at 34,890,488 bp
  • A to G, chromosome 14 at 37,068,045 bp
  • C to T, chromosome 14 at 70,531,029 bp
  • T to C, chromosome 15 at 51,882,511 bp
  • C to T, chromosome 15 at 76,690,799 bp
  • T to C, chromosome 15 at 81,337,959 bp
  • T to A, chromosome 15 at 103,455,028 bp
  • A to T, chromosome 16 at 29,629,635 bp
  • C to A, chromosome 16 at 85,799,614 bp
  • G to A, chromosome 17 at 23,670,239 bp
  • A to T, chromosome 17 at 37,589,415 bp
  • A to G, chromosome 18 at 47,290,177 bp
  • A to T, chromosome 18 at 74,742,171 bp
  • C to A, chromosome 19 at 6,228,431 bp
  • T to C, chromosome 19 at 37,686,633 bp
  • C to T, chromosome 19 at 46,366,504 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0114 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038400-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.