Strain Name:
C57BL/6J-MtgxR1568Btlr/Mmmh
Stock Number:
039607-MU
Citation ID:
RRID:MMRRC_039607-MU
Other Names:
R1568 (G1), C57BL/6J-MtgxR1568Btlr
Major Collection:

Strain Information

Bdnf
Name: brain derived neurotrophic factor
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12064
HGNC: HGNC:1033
Homologene: 7245
Slc6a1
Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 1
Synonyms: XT-1, Xtrp1, Gabt1, Gat1, Gabt, GAT-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232333
Homologene: 2290
Nfia
Name: nuclear factor I/A
Synonyms: 9430022M17Rik, NF1A, NF1-A, 1110047K16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18027
HGNC: HGNC:7784
Homologene: 4086
Secisbp2
Name: SECIS binding protein 2
Synonyms: 2210413N07Rik, 2810012K13Rik, SBP2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75420
Homologene: 11415
Nfya
Name: nuclear transcription factor-Y alpha
Synonyms: Sez10, Cbf-b
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18044
HGNC: HGNC:7804
Homologene: 32114
Virma
Name: vir like m6A methyltransferase associated
Synonyms: 1110037F02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66185
Homologene: 41043
Proser1
Name: proline and serine rich 1
Synonyms: 2810046L04Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 212127
Homologene: 13463
Sf3b1
Name: splicing factor 3b, subunit 1
Synonyms: Targ4, SAP155, 2810001M05Rik, SF3b155, Prp10
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 81898
Homologene: 6696
Fasn
Name: fatty acid synthase
Synonyms: A630082H08Rik, FAS
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14104
HGNC: HGNC:3594
Homologene: 55800
Osr1
Name: odd-skipped related transcription factor 1
Synonyms: Odd1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 23967
VEGA: 12
HGNC: HGNC:8111
Homologene: 8035
Myh14
Name: myosin, heavy polypeptide 14
Synonyms: NMHC II-C, 2400004E04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71960
Homologene: 23480
Clca2
Name: chloride channel accessory 2
Synonyms: Clca5
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229933
HGNC: HGNC:2016
Homologene: 4765
Dsp
Name: desmoplakin
Synonyms: 5730453H04Rik, DP, rul, 2300002E22Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Adam18
Name: a disintegrin and metallopeptidase domain 18
Synonyms: Dtgn3, Adam27
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13524
HGNC: HGNC:196
Homologene: 74941
Clca4a
Name: chloride channel accessory 4A
Synonyms: Clca6, 9130020L07Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99663
HGNC: HGNC:2018
Homologene: 40808
Ppp3ca
Name: protein phosphatase 3, catalytic subunit, alpha isoform
Synonyms: 2900074D19Rik, CnA, CN, Calna, Caln, PP2BA alpha, PP2B alpha 1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 19055
HGNC: HGNC:9314
Homologene: 55497
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: Dnchc2, m152Asp, m407Asp, b2b414Clo, D030010H02Rik, D330044F14Rik, 4432416O06Rik, DHC1b, DHC2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Cenpe
Name: centromere protein E
Synonyms: Kif10, 312kDa, CENP-E, N-7 kinesin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229841
HGNC: HGNC:1856
Homologene: 20429
Magi3
Name: membrane associated guanylate kinase, WW and PDZ domain containing 3
Synonyms: 4732496O19Rik, 6530407C02Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99470
Homologene: 26431
Cblb
Name: Casitas B-lineage lymphoma b
Synonyms: Cbl-b
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208650
VEGA: 16
HGNC: HGNC:1542
Homologene: 15856
Dna2
Name: DNA replication helicase/nuclease 2
Synonyms: E130315B21Rik, Dna2l
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 327762
HGNC: HGNC:2939
Homologene: 6124
Sec22a
Name: SEC22 homolog A, vesicle trafficking protein
Synonyms: 1810005C06Rik, Sec22l2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 317717
Homologene: 8246
Pde4b
Name: phosphodiesterase 4B, cAMP specific
Synonyms: dunce, Dpde4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18578
HGNC: HGNC:8781
Homologene: 1953
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: Dnahc5, Mdnah5, b2b1134Clo, b2b1154Clo, b2b1537Clo, b2b1565Clo, b2b3491Clo
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 192190
Homologene: 16332
Clspn
Name: claspin
Synonyms: E130314M08Rik, C85083
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269582
Homologene: 11138
Cacna1d
Name: calcium channel, voltage-dependent, L type, alpha 1D subunit
Synonyms: Cchl1a2, Cav1.3alpha1, 8430418G19Rik, Cchl1a, D-LTCC, Cacnl1a2, C79217
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12289
VEGA: 14
HGNC: HGNC:1391
Homologene: 578
Sybu
Name: syntabulin (syntaxin-interacting)
Synonyms: Golsyn/Syntabulin, A830027B17Rik, 5730410E15Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 319613
VEGA: 15
Homologene: 9838
Cpne8
Name: copine VIII
Synonyms: 1500031E20Rik, 1200003E11Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66871
Homologene: 12049
Spata31e2
Name: spermatogenesis associated 31 subfamily E member 2
Synonyms: 4931408C20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210940
Homologene: 86827
Lrguk
Name: leucine-rich repeats and guanylate kinase domain containing
Synonyms: 4921528H16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74354
Homologene: 34923
Insr
Name: insulin receptor
Synonyms: 4932439J01Rik, IR, D630014A15Rik, IR-A, IR-B, CD220
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16337
HGNC: HGNC:6091
Homologene: 20090
Arhgef38
Name: Rho guanine nucleotide exchange factor 38
Synonyms: D630013G24Rik, 9130221D24Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 77669
Homologene: 137396
Ahnak
Name: AHNAK nucleoprotein
Synonyms: DY6, 1110004P15Rik, 2310047C17Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Pde8a
Name: phosphodiesterase 8A
Synonyms: Pde8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18584
HGNC: HGNC:8793
Homologene: 1957
Adgb
Name: androglobin
Synonyms: 9130014G24Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215772
Homologene: 100289
Vwde
Name: von Willebrand factor D and EGF domains
Synonyms: LOC232585
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232585
Homologene: 35456
Zyg11a
Name: zyg-11 family member A, cell cycle regulator
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230590
Homologene: 66294
Or4f57
Name: olfactory receptor family 4 subfamily F member 57
Synonyms: Olfr1308, GA_x6K02T2Q125-73008844-73007882, MOR245-22
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258258
Homologene: 45797
Krt76
Name: keratin 76
Synonyms: 2310001L23Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 77055
Homologene: 22931
Prl8a9
Name: prolactin family8, subfamily a, member 9
Synonyms: PLP-Cbeta, Prlpc2, 1600019F10Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 67310
Homologene: 11344
Sanbr
Name: SANT and BTB domain regulator of CSR
Synonyms: 0610010F05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71675
Homologene: 19038
Or9s14
Name: olfactory receptor family 9 subfamily S member 14
Synonyms: Olfr1410, GA_x6K02T2R7CC-81146179-81145211, MOR208-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258484
Homologene: 74205
Adamdec1
Name: ADAM-like, decysin 1
Synonyms: Dcsn, 2210414L24Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 58860
VEGA: 14
Homologene: 8711
Slc39a10
Name: solute carrier family 39 (zinc transporter), member 10
Synonyms: 2900042E17Rik, Zip10
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227059
Homologene: 34076
Lgmn
Name: legumain
Synonyms: preprolegumain, Prsc1, AEP
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 19141
HGNC: HGNC:9472
Homologene: 38075
Adra1d
Name: adrenergic receptor, alpha 1d
Synonyms: Adra-1, alpha1D-AR, Gpcr8, Adra1, Adra1a
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11550
HGNC: HGNC:280
Homologene: 551
Or52n4
Name: olfactory receptor family 52 subfamily N member 4
Synonyms: GA_x6K02T2PBJ9-7273558-7272587, MOR34-5, Olfr658
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259051
Homologene: 105161
Aars2
Name: alanyl-tRNA synthetase 2, mitochondrial
Synonyms: Aarsl
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224805
VEGA: 17
Homologene: 56897
Spag6l
Name: sperm associated antigen 6-like
Synonyms: Spag6, PF16
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 50525
Homologene: 8252
Lamp3
Name: lysosomal-associated membrane protein 3
Synonyms: DC-LAMP, Cd208, 1200002D17Rik, TSC403
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239739
VEGA: 16
Homologene: 8670
Icosl
Name: icos ligand
Synonyms: GL50-B, B7RP-1, B7h, B7-H2, ICOS-L, LICOS, GL50
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 50723
VEGA: 10
Homologene: 49412
Serpinb6b
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6b
Synonyms: Spi12, ovalbumin, NK13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20708
HGNC: HGNC:8950
Homologene: 22633
Ankmy1
Name: ankyrin repeat and MYND domain containing 1
Synonyms: 4930483I10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241158
Homologene: 9561
Atp8b4
Name: ATPase, class I, type 8B, member 4
Synonyms: Im
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241633
Homologene: 133162
Lpgat1
Name: lysophosphatidylglycerol acyltransferase 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226856
Homologene: 8914
D6Ertd527e
Name: DNA segment, Chr 6, ERATO Doi 527, expressed
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 52372
Vmn2r86
Name: vomeronasal 2, receptor 86
Synonyms: EG625109
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 625109
Homologene: 129606
Cd163
Name: CD163 antigen
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 93671
HGNC: HGNC:1631
Homologene: 128811
Atp8b2
Name: ATPase, class I, type 8B, member 2
Synonyms: Id
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 54667
Homologene: 23226
Rgs20
Name: regulator of G-protein signaling 20
Synonyms: Rgsz1, 2900073E09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 58175
Homologene: 2745
Zfp873
Name: zinc finger protein 873
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 408062
Homologene: 134319
Vmn1r229
Name: vomeronasal 1 receptor 229
Synonyms: V1re1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 171224
Homologene: 74319
Npffr1
Name: neuropeptide FF receptor 1
Synonyms: NPFF1R, NPFF1, Gpr147, LOC237362
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237362
Homologene: 23348
Or5b112
Name: olfactory receptor family 5 subfamily B member 112
Synonyms: Olfr1466, MOR202-12, GA_x6K02T2RE5P-3672907-3673839
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258689
HGNC: HGNC:8324
Homologene: 133677
Vmn1r238
Name: vomeronasal 1 receptor, 238
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 100312476
Homologene: 128342
Ghdc
Name: GH3 domain containing
Synonyms: D11Lgp1e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 80860
Homologene: 32760
Wfdc13
Name: WAP four-disulfide core domain 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 408190
Homologene: 134107
Klrc3
Name: killer cell lectin-like receptor subfamily C, member 3
Synonyms: NKG2E
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 58179
Homologene: 130643
Gins2
Name: GINS complex subunit 2
Synonyms: Psf2, 4833427B12Rik, 2210013I18Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 272551
Homologene: 41105
Spag6
Name: sperm associated antigen 6
Synonyms: Spag6l, BC061194
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381350
Homologene: 133723
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 5,020,827 bp
  • T to C, chromosome 1 at 26,685,869 bp
  • A to T, chromosome 1 at 46,826,215 bp
  • C to G, chromosome 1 at 55,019,395 bp
  • T to C, chromosome 1 at 92,607,954 bp
  • T to C, chromosome 1 at 92,881,116 bp
  • A to T, chromosome 1 at 191,776,426 bp
  • A to G, chromosome 2 at 18,733,114 bp
  • A to G, chromosome 2 at 109,723,794 bp
  • C to A, chromosome 2 at 111,960,240 bp
  • G to T, chromosome 2 at 126,325,394 bp
  • T to C, chromosome 2 at 131,546,172 bp
  • G to T, chromosome 2 at 164,686,934 bp
  • T to C, chromosome 3 at 53,477,759 bp
  • T to C, chromosome 3 at 89,949,848 bp
  • A to C, chromosome 3 at 104,089,527 bp
  • C to T, chromosome 3 at 133,132,464 bp
  • T to A, chromosome 3 at 135,239,758 bp
  • A to G, chromosome 3 at 136,928,544 bp
  • A to G, chromosome 3 at 144,952,929 bp
  • A to T, chromosome 3 at 145,075,649 bp
  • T to C, chromosome 4 at 11,528,776 bp
  • T to G, chromosome 4 at 98,111,224 bp
  • A to C, chromosome 4 at 102,597,699 bp
  • A to G, chromosome 4 at 108,183,646 bp
  • T to A, chromosome 4 at 126,581,517 bp
  • G to T, chromosome 6 at 13,187,800 bp
  • T to A, chromosome 6 at 34,086,438 bp
  • C to G, chromosome 6 at 87,111,524 bp
  • G to T, chromosome 6 at 114,307,770 bp
  • T to A, chromosome 6 at 124,326,154 bp
  • T to C, chromosome 6 at 129,639,547 bp
  • G to A, chromosome 7 at 44,611,698 bp
  • A to G, chromosome 7 at 81,292,263 bp
  • T to A, chromosome 7 at 104,644,770 bp
  • A to T, chromosome 8 at 3,165,576 bp
  • T to G, chromosome 8 at 24,647,783 bp
  • T to C, chromosome 8 at 120,582,200 bp
  • T to C, chromosome 9 at 7,157,553 bp
  • A to T, chromosome 10 at 10,442,665 bp
  • T to A, chromosome 10 at 61,626,233 bp
  • C to T, chromosome 10 at 62,949,187 bp
  • T to C, chromosome 10 at 78,077,882 bp
  • C to A, chromosome 10 at 82,060,279 bp
  • C to T, chromosome 10 at 130,453,141 bp
  • T to C, chromosome 11 at 23,589,971 bp
  • A to G, chromosome 11 at 100,768,505 bp
  • A to T, chromosome 11 at 120,813,249 bp
  • G to A, chromosome 12 at 9,579,798 bp
  • T to C, chromosome 12 at 102,394,609 bp
  • A to T, chromosome 13 at 27,561,542 bp
  • T to C, chromosome 13 at 32,974,912 bp
  • T to C, chromosome 13 at 38,175,147 bp
  • A to G, chromosome 13 at 51,673,107 bp
  • G to T, chromosome 14 at 30,075,267 bp
  • T to A, chromosome 14 at 68,570,883 bp
  • T to A, chromosome 15 at 28,409,177 bp
  • A to T, chromosome 15 at 44,545,501 bp
  • G to T, chromosome 15 at 44,718,832 bp
  • G to T, chromosome 15 at 90,619,642 bp
  • T to A, chromosome 15 at 101,885,008 bp
  • A to T, chromosome 16 at 19,673,525 bp
  • T to C, chromosome 16 at 35,347,628 bp
  • C to T, chromosome 16 at 52,135,829 bp
  • T to A, chromosome 17 at 20,814,805 bp
  • G to T, chromosome 17 at 45,516,088 bp
  • A to C, chromosome 17 at 48,391,234 bp
  • T to C, chromosome 18 at 3,123,358 bp
  • G to A, chromosome 19 at 9,002,375 bp
  • C to A, chromosome 19 at 13,342,175 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1568 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039607-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.