Strain Name:
C57BL/6J-MtgxR6038Btlr/Mmmh
Stock Number:
044208-MU
Citation ID:
RRID:MMRRC_044208-MU
Other Names:
R6038 (G1)
Major Collection:

Strain Information

Epha7
Name: Eph receptor A7
Synonyms: MDK1, Hek11, Mdk1, Cek11, Ebk, Ehk3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13841
HGNC: HGNC:3390
Homologene: 20935
Epb41l4a
Name: erythrocyte membrane protein band 4.1 like 4a
Synonyms: Epb4.1l4a, NBL4
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13824
VEGA: 18
Homologene: 8398
Pnmt
Name: phenylethanolamine-N-methyltransferase
Synonyms: Pent
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18948
HGNC: HGNC:9160
Homologene: 55673
Smarcad1
Name: SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
Synonyms: Etl1, D6Pas1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13990
Homologene: 5301
Cabin1
Name: calcineurin binding protein 1
Synonyms: A330070M20Rik, Cain, Ppp3in
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 104248
VEGA: 10
Homologene: 49307
Larp1
Name: La ribonucleoprotein 1, translational regulator
Synonyms: 1810024J12Rik, 3110040D16Rik, Larp
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 73158
Homologene: 9089
Coro7
Name: coronin 7
Synonyms: 0610011B16Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78885
Homologene: 11573
Sap130
Name: Sin3A associated protein
Synonyms: 2610304F09Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 269003
VEGA: 18
Homologene: 11577
Dock4
Name: dedicator of cytokinesis 4
Synonyms: EST N28122, 6330411N01Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238130
VEGA: 12
Homologene: 56680
Mtrex
Name: Mtr4 exosome RNA helicase
Synonyms: 2610528A15Rik, Skiv2l2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 72198
VEGA: 13
Homologene: 6257
Zbtb17
Name: zinc finger and BTB domain containing 17
Synonyms: Miz1, Zfp100, mZ13
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22642
Homologene: 2575
Nhp2
Name: NHP2 ribonucleoprotein
Synonyms: Nola2, D11Ertd175e, 2410130M07Rik, H/ACA small nucleolar RNPs, NHP2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 52530
Homologene: 5524
Slc12a3
Name: solute carrier family 12, member 3
Synonyms: TSC, NCC
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20497
Homologene: 287
Prom1
Name: prominin 1
Synonyms: Prom-1, Prom, AC133, 4932416E19Rik, CD133
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19126
HGNC: HGNC:9454
Homologene: 4390
Arid1b
Name: AT-rich interaction domain 1B
Synonyms: 9330189K18Rik, B230217J03Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 239985
Homologene: 32344
Cntnap1
Name: contactin associated protein-like 1
Synonyms: Nrxn4, p190, NCP1, shm, paranodin, Caspr
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 53321
HGNC: HGNC:8011
Homologene: 2693
Pebp1
Name: phosphatidylethanolamine binding protein 1
Synonyms: Pebp1, Raf-1 inhibitor protein, Pbp1, RKIP, Pbpr
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 23980
HGNC: HGNC:8630
Homologene: 37637
Spag9
Name: sperm associated antigen 9
Synonyms: 3110018C07Rik, Mapk8ip4, 4831406C20Rik, syd1, JLP, 4733401I23Rik, JIP4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70834
Homologene: 2954
Adgra3
Name: adhesion G protein-coupled receptor A3
Synonyms: 3830613O22Rik, Tem5-like, Gpr125
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70693
Homologene: 19235
Tln1
Name: talin 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21894
Homologene: 21267
Pfkp
Name: phosphofructokinase, platelet
Synonyms: 9330125N24Rik, PFK-C, 1200015H23Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 56421
HGNC: HGNC:8878
Homologene: 20579
Osbpl7
Name: oxysterol binding protein-like 7
Synonyms: 4933437E18Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71240
Homologene: 79672
Baiap3
Name: BAI1-associated protein 3
Synonyms: LOC381076
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 545192
HGNC: HGNC:948
Homologene: 20844
Steap3
Name: STEAP family member 3
Synonyms: 1010001D01Rik, pHyde
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68428
Homologene: 10084
Egln3
Name: egl-9 family hypoxia-inducible factor 3
Synonyms: Hif-p4h-3, 2610021G09Rik, SM-20, Phd3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 112407
Homologene: 32531
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: 4930545D19Rik, hyrh, hy-3, hy3, 1700034M11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244653
Homologene: 52118
Cspg4b
Name: chondroitin sulfate proteoglycan 4B
Synonyms: BC067074
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 408066
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, D12Ertd777e, diminished cone electroretinogram, Cpfl8, Nesp2g, dice, syne-2, 6820443O06Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 319565
Homologene: 56700
Col28a1
Name: collagen, type XXVIII, alpha 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213945
Homologene: 66345
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, Dnahcl1, Dnahc17, 2810003K23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Lrp12
Name: low density lipoprotein-related protein 12
Synonyms: C820005L12Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239393
Homologene: 8385
Mrc1
Name: mannose receptor, C type 1
Synonyms: MR, CD206
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17533
HGNC: HGNC:7228
Homologene: 37622
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244484
Homologene: 12460
Rubcnl
Name: RUN and cysteine rich domain containing beclin 1 interacting protein like
Synonyms: 5031414D18Rik, LOC380917
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 271221
VEGA: 14
Homologene: 57021
Gxylt2
Name: glucoside xylosyltransferase 2
Synonyms: LOC232313, Glt8d4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232313
Homologene: 16823
Fetub
Name: fetuin beta
Synonyms: D17980, 2310011O17Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 59083
VEGA: 16
HGNC: HGNC:3658
Homologene: 8660
Or11g25
Name: olfactory receptor family 11 subfamily G member 25
Synonyms: Olfr741, GA_x6K02T2PMLR-6197851-6198786, MOR106-15, MOR106-10
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258233
Mdga2
Name: MAM domain containing glycosylphosphatidylinositol anchor 2
Synonyms: 9330209L04Rik, Mamdc1, Adp, Mdga2, 6720489L24Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320772
Homologene: 45659
Speg
Name: SPEG complex locus
Synonyms: D1Bwg1450e, BPEG, Apeg1, SPEG, SPEGalpha, SPEGbeta
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11790
Homologene: 55619
Garin5b
Name: golgi associated RAB2 interactor family member 5B
Synonyms: 4930401F20Rik, Fam71e2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243822
Homologene: 89225
Wdhd1
Name: WD repeat and HMG-box DNA binding protein 1
Synonyms: AND-1, D630024B06Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218973
Homologene: 56019
Nrm
Name: nurim (nuclear envelope membrane protein)
Synonyms: 2610307M02Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106582
HGNC: HGNC:8003
Homologene: 38294
Adgrf1
Name: adhesion G protein-coupled receptor F1
Synonyms: Gpr110, 5031409J19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 77596
Homologene: 124643
Garin4
Name: golgi associated RAB2 interactor family member 4
Synonyms: 4933417M04Rik, Fam71a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 619288
Homologene: 77474
Adcy7
Name: adenylate cyclase 7
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11513
HGNC: HGNC:238
Homologene: 866
Vmn2r60
Name: vomeronasal 2, receptor 60
Synonyms: Casr-rs3, Gprc2a-rs3, EG637898
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 637898
Homologene: 129683
Antxr1
Name: anthrax toxin receptor 1
Synonyms: 2810405N18Rik, Tem8, 2310008J16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 69538
Homologene: 12976
Slc24a5
Name: solute carrier family 24, member 5
Synonyms: Oca6, F630045L20Rik, NCKX5, NCX5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 317750
Homologene: 18400
Defb19
Name: defensin beta 19
Synonyms: Tdl
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 246700
Homologene: 17045
Kndc1
Name: kinase non-catalytic C-lobe domain (KIND) containing 1
Synonyms: 2410012C07Rik, very-kind, VKIND, B830014K08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76484
Homologene: 45138
Abcc10
Name: ATP-binding cassette, sub-family C member 10
Synonyms: Mrp7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224814
HGNC: HGNC:52
Homologene: 58616
Hk3
Name: hexokinase 3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 212032
HGNC: HGNC:4925
Homologene: 55633
Serpina1e
Name: serine (or cysteine) peptidase inhibitor, clade A, member 1E
Synonyms: Spi1-5, PI5
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20704
HGNC: HGNC:8941
Homologene: 20103
Hecw1
Name: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
Synonyms: NEDL1, E130207I19Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 94253
VEGA: 13
Homologene: 9004
Or7e165
Name: olfactory receptor family 7 subfamily E member 165
Synonyms: GA_x6K02T2PVTD-13523015-13523944, IG6, Olfr58, MOR146-3, MOR146-7P
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18358
Homologene: 134093
Ppl
Name: periplakin
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19041
VEGA: 16
HGNC: HGNC:9273
Homologene: 2026
H2-M10.3
Name: histocompatibility 2, M region locus 10.3
Synonyms: 5.3H
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 110696
Homologene: 117973
Garin5a
Name: golgi associated RAB2 interactor 5A
Synonyms: 1700021P22Rik, 1700021N13Rik, Fam71e1, 0610007G24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75538
Homologene: 19259
Akirin1
Name: akirin 1
Synonyms: 6330407G11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68050
Homologene: 11348
Xbp1
Name: X-box binding protein 1
Synonyms: D11Ertd39e, TREB5, TREB-5, XBP-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22433
Homologene: 3722
Tas2r114
Name: taste receptor, type 2, member 114
Synonyms: T2R14, mt2r46, mGR14, Tas2r14
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387346
Homologene: 128355
Or10ag54
Name: olfactory receptor family 10 subfamily AG member 54
Synonyms: GA_x6K02T2Q125-48753766-48754734, Olfr1116-ps, Olfr1116, Olfr1521-ps1, MOR264-21P, MOR264-8P
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257875
Homologene: 134077
Tcl1b4
Name: T cell leukemia/lymphoma 1B, 4
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 27380
VEGA: 12
Homologene: 83274
Gm29587
Name: predicted gene 29587
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 75,418,459 bp
  • A to G, chromosome 1 at 120,241,641 bp
  • C to T, chromosome 1 at 191,162,722 bp
  • G to C, chromosome 2 at 14,257,071 bp
  • T to A, chromosome 2 at 87,269,267 bp
  • A to G, chromosome 2 at 125,085,731 bp
  • T to G, chromosome 2 at 152,576,267 bp
  • G to A, chromosome 4 at 28,821,521 bp
  • G to C, chromosome 4 at 43,555,052 bp
  • A to G, chromosome 4 at 123,750,163 bp
  • A to G, chromosome 4 at 141,464,441 bp
  • A to T, chromosome 5 at 44,001,793 bp
  • A to T, chromosome 5 at 49,999,145 bp
  • A to T, chromosome 5 at 117,284,105 bp
  • T to C, chromosome 6 at 8,013,140 bp
  • T to C, chromosome 6 at 65,073,248 bp
  • C to A, chromosome 6 at 87,287,000 bp
  • T to A, chromosome 6 at 100,804,594 bp
  • A to T, chromosome 6 at 131,689,481 bp
  • T to C, chromosome 7 at 4,753,595 bp
  • C to A, chromosome 7 at 42,194,962 bp
  • C to T, chromosome 7 at 44,500,295 bp
  • CT to C, chromosome 7 at 139,923,775 bp
  • A to G, chromosome 8 at 54,632,311 bp
  • A to G, chromosome 8 at 88,322,980 bp
  • T to G, chromosome 8 at 94,330,472 bp
  • A to G, chromosome 8 at 110,599,031 bp
  • A to G, chromosome 9 at 19,783,562 bp
  • A to G, chromosome 10 at 75,739,366 bp
  • T to C, chromosome 11 at 5,524,798 bp
  • T to C, chromosome 11 at 51,620,085 bp
  • A to G, chromosome 11 at 58,041,605 bp
  • C to G, chromosome 11 at 94,112,092 bp
  • C to T, chromosome 11 at 97,050,716 bp
  • G to A, chromosome 11 at 98,387,768 bp
  • G to A, chromosome 11 at 101,184,636 bp
  • T to C, chromosome 11 at 118,055,889 bp
  • A to T, chromosome 12 at 40,733,351 bp
  • A to G, chromosome 12 at 54,181,690 bp
  • A to T, chromosome 12 at 66,630,053 bp
  • G to A, chromosome 12 at 74,222,535 bp
  • C to T, chromosome 12 at 75,878,384 bp
  • A to T, chromosome 12 at 103,946,836 bp
  • T to C, chromosome 12 at 105,202,507 bp
  • G to T, chromosome 13 at 6,597,969 bp
  • G to T, chromosome 13 at 14,346,062 bp
  • T to C, chromosome 13 at 55,006,560 bp
  • A to T, chromosome 13 at 112,891,290 bp
  • G to A, chromosome 13 at 113,318,619 bp
  • T to C, chromosome 14 at 47,263,580 bp
  • T to C, chromosome 14 at 50,486,220 bp
  • T to C, chromosome 14 at 75,031,970 bp
  • A to C, chromosome 15 at 39,872,380 bp
  • A to T, chromosome 16 at 4,679,550 bp
  • A to T, chromosome 16 at 5,102,581 bp
  • C to T, chromosome 16 at 22,932,331 bp
  • A to T, chromosome 17 at 5,336,682 bp
  • T to C, chromosome 17 at 25,246,334 bp
  • T to C, chromosome 17 at 35,861,505 bp
  • C to A, chromosome 17 at 36,368,395 bp
  • T to C, chromosome 17 at 43,295,209 bp
  • A to G, chromosome 17 at 46,304,360 bp
  • T to A, chromosome 18 at 31,680,486 bp
  • T to C, chromosome 18 at 33,854,335 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6038 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044208-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.