Strain Name:
C57BL/6J-MtgxR6806Btlr/Mmmh
Stock Number:
044919-MU
Citation ID:
RRID:MMRRC_044919-MU
Other Names:
R6806 (G1)
Major Collection:

Strain Information

Chrna3
Name: cholinergic receptor, nicotinic, alpha polypeptide 3
Synonyms: neuronal nicotinic acetylcholine receptor, alpha 3 subunit, Acra3, (a)3, Acra-3, A730007P14Rik, alpha 3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110834
VEGA: 9
HGNC: HGNC:1957
Homologene: 591
Trp53bp1
Name: transformation related protein 53 binding protein 1
Synonyms: p53BP1, 53BP1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27223
Homologene: 4137
Rsrc2
Name: arginine/serine-rich coiled-coil 2
Synonyms: 1500011J06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 208606
Homologene: 133892
Rsf1
Name: remodeling and spacing factor 1
Synonyms: p325, 4832420A03Rik, Hbxap, C030033M12Rik, XAP8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: Pcp-1, opt, P400, InsP3R type I, Itpr-1, wblo, IP3R1, Ip3r, Pcp1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Sh3d19
Name: SH3 domain protein D19
Synonyms: Kryn
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 27059
Homologene: 19064
Zfp719
Name: zinc finger protein 719
Synonyms: C630016O21Rik, mszf6, 9430094P17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210105
Ptk7
Name: PTK7 protein tyrosine kinase 7
Synonyms: 8430404F20Rik, mPTK7/CCK4, chz
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71461
VEGA: 17
HGNC: HGNC:9618
Homologene: 43672
Ubr3
Name: ubiquitin protein ligase E3 component n-recognin 3
Synonyms: 1110059H15Rik, 4833421P10Rik, A130030D10Rik, Zfp650
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68795
Homologene: 52092
Tenm4
Name: teneurin transmembrane protein 4
Synonyms: Ten-m4, ELM2, Odz4, l(7)-3Rn, Doc4, l7Rn3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 23966
Homologene: 8034
Pank2
Name: pantothenate kinase 2
Synonyms: 4933409I19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74450
Homologene: 65126
Bach2
Name: BTB and CNC homology, basic leucine zipper transcription factor 2
Synonyms: E030004N02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12014
Homologene: 7240
Prss58
Name: serine protease 58
Synonyms: BC048599
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232717
Homologene: 65285
Muc16
Name: mucin 16
Synonyms: LOC385009, 1110008I14Rik, Gm21044
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73732
Homologene: 141193
Magi3
Name: membrane associated guanylate kinase, WW and PDZ domain containing 3
Synonyms: 4732496O19Rik, 6530407C02Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99470
Homologene: 26431
Rbm45
Name: RNA binding motif protein 45
Synonyms: Drbp1, G430095G15Rik, Drb1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241490
Homologene: 15560
Dnah11
Name: dynein, axonemal, heavy chain 11
Synonyms: Dnahc11, b2b1279Clo, b2b1203Clo, avc4, b2b1289Clo, b2b598Clo, lrd, b2b1727Clo
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13411
HGNC: HGNC:2942
Homologene: 2801
Agbl1
Name: ATP/GTP binding protein-like 1
Synonyms: EG244071, Ccp4, Nna1-l1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244071
Homologene: 17552
Cplane1
Name: ciliogenesis and planar polarity effector 1
Synonyms: Hug, 2410089E03Rik, b2b012Clo, Jbts17
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 73692
Homologene: 11315
Tnn
Name: tenascin N
Synonyms: Tnw, tenascin-W
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329278
Homologene: 18634
Lrrc37
Name: leucine rich repeat containing 37
Synonyms: Gm884, LOC380730
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380730
Homologene: 134511
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Grin2b
Name: glutamate receptor, ionotropic, NMDA2B (epsilon 2)
Synonyms: NR2B, GluRepsilon2, Nmdar2b, GluN2B, NMDAR2B
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14812
HGNC: HGNC:4586
Homologene: 646
Stkld1
Name: serine/threonine kinase-like domain containing 1
Synonyms: Gm711, LOC279029
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 279029
Homologene: 19586
Ifi206
Name: interferon activated gene 206
Synonyms: Gm4955, Pyblhin-C
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 102639543
HGNC: HGNC:5395
Homologene: 115929
Atp13a4
Name: ATPase type 13A4
Synonyms: 9330174J19Rik, 4631413J11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224079
Homologene: 75330
Nprl3
Name: nitrogen permease regulator-like 3
Synonyms: m(alpha)RE, Mare, -14 gene, HS-40, Prox1, Phg, HS-26
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17168
Homologene: 8091
Tmf1
Name: TATA element modulatory factor 1
Synonyms: 7030402D04Rik, LOC232286
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232286
Homologene: 133801
Cntnap5b
Name: contactin associated protein-like 5B
Synonyms: C230078M14Rik, Caspr5-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241175
Homologene: 104295
Or51q1
Name: olfactory receptor family 51 subfamily Q member 1
Synonyms: GA_x6K02T2PBJ9-6713641-6714588, Olfr635, MOR5-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259122
Homologene: 133592
Nphp4
Name: nephronophthisis 4 (juvenile) homolog (human)
Synonyms: nmf192, 4930564O18Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 260305
Homologene: 9024
Ccdc186
Name: coiled-coil domain containing 186
Synonyms: Otg1, 1810028B20Rik, A630007B06Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 213993
Homologene: 9963
Apba2
Name: amyloid beta precursor protein binding family A member 2
Synonyms: X11L, X11-like, Mint 2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11784
HGNC: HGNC:579
Homologene: 4021
Zfp446
Name: zinc finger protein 446
Synonyms: A630035I11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269870
Homologene: 9910
Rassf7
Name: Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
Synonyms: 2400009B11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66985
HGNC: HGNC:1166
Homologene: 2595
Saxo2
Name: stabilizer of axonemal microtubules 2
Synonyms: Fam154b, 1700129I04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330577
Homologene: 25135
Ebna1bp2
Name: EBNA1 binding protein 2
Synonyms: B830003A16Rik, p40, 1810014B19Rik, Ebp2, Nobp
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69072
Homologene: 4969
Zfp747l1
Name: zinc finger protein 747 like 1
Synonyms: 9130019O22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 78921
Homologene: 118005
Spata31d1a
Name: spermatogenesis associated 31 subfamily D, member 1A
Synonyms: 1700013B16Rik, Fam75d1a, Fam75d3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 72219
VEGA: 13
Homologene: 122131
Zfp978
Name: zinc finger protein 978
Synonyms: Gm13145
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 108168963
Trgj4
Name: T cell receptor gamma joining 4
Synonyms: Gm16673
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 100126434
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 99,940,649 bp
  • T to C, chromosome 1 at 160,120,708 bp
  • C to T, chromosome 1 at 173,481,571 bp
  • C to G, chromosome 2 at 26,943,910 bp
  • T to C, chromosome 2 at 69,955,964 bp
  • C to T, chromosome 2 at 76,380,460 bp
  • T to C, chromosome 2 at 121,228,666 bp
  • T to C, chromosome 2 at 131,262,707 bp
  • T to A, chromosome 3 at 86,104,333 bp
  • T to A, chromosome 3 at 104,046,969 bp
  • T to A, chromosome 4 at 32,575,301 bp
  • T to C, chromosome 4 at 118,620,977 bp
  • G to A, chromosome 4 at 147,390,827 bp
  • G to T, chromosome 4 at 152,538,101 bp
  • T to G, chromosome 5 at 123,739,531 bp
  • A to T, chromosome 6 at 40,897,732 bp
  • G to A, chromosome 6 at 97,161,447 bp
  • G to A, chromosome 6 at 108,515,947 bp
  • A to G, chromosome 6 at 135,774,828 bp
  • T to C, chromosome 7 at 12,979,116 bp
  • A to G, chromosome 7 at 43,586,385 bp
  • T to A, chromosome 7 at 64,695,459 bp
  • A to G, chromosome 7 at 76,425,921 bp
  • A to T, chromosome 7 at 82,635,032 bp
  • A to G, chromosome 7 at 96,811,959 bp
  • ATGGCG to ATGGCGACGGTGGCG, chromosome 7 at 97,579,904 bp
  • G to T, chromosome 7 at 103,979,564 bp
  • T to C, chromosome 7 at 127,386,594 bp
  • A to G, chromosome 7 at 141,216,809 bp
  • A to G, chromosome 9 at 18,537,910 bp
  • C to T, chromosome 9 at 55,015,810 bp
  • A to G, chromosome 11 at 32,267,509 bp
  • T to C, chromosome 11 at 103,621,124 bp
  • T to C, chromosome 12 at 84,809,238 bp
  • T to C, chromosome 12 at 117,987,676 bp
  • T to C, chromosome 13 at 19,342,195 bp
  • A to T, chromosome 13 at 59,703,218 bp
  • A to G, chromosome 15 at 8,186,858 bp
  • A to G, chromosome 16 at 29,469,280 bp
  • C to T, chromosome 17 at 46,573,528 bp
  • T to A, chromosome 19 at 56,800,129 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6806 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044919-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.