Strain Name:
C57BL/6J-MtgxR9062Btlr/Mmmh
Stock Number:
068888-MU
Citation ID:
RRID:MMRRC_068888-MU
Other Names:
R9062 (G1)
Major Collection:

Strain Information

Notch3
Name: notch 3
Synonyms: N3, hpbk
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18131
HGNC: HGNC:7883
Homologene: 376
Cnst
Name: consortin, connexin sorting protein
Synonyms: 9630058J23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226744
Homologene: 17139
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Phr1, C130061D10Rik, Pam
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105689
Homologene: 9005
Ambra1
Name: autophagy/beclin 1 regulator 1
Synonyms: D030051N19Rik, 2310079H06Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228361
Homologene: 18204
Etl4
Name: enhancer trap locus 4
Synonyms: Sickle tail, 6620402G01Rik, Skt, 9430077C05Rik, Etl-4, E330027G05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 208618
Homologene: 10477
Zfp64
Name: zinc finger protein 64
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22722
Homologene: 7604
Skp2
Name: S-phase kinase-associated protein 2
Synonyms: FBXL1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 27401
Homologene: 55942
Cep78
Name: centrosomal protein 78
Synonyms: 5730599I05Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 208518
VEGA: 19
Homologene: 11030
Atxn10
Name: ataxin 10
Synonyms: Sca10, Tex169, E46, TEG-169
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 54138
VEGA: 15
Homologene: 40858
Mlf2
Name: myeloid leukemia factor 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 30853
HGNC: HGNC:7126
Homologene: 3968
Cyth1
Name: cytohesin 1
Synonyms: CTH-1, Pscd1, CLM1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19157
HGNC: HGNC:9501
Homologene: 31262
Atp5f1a
Name: ATP synthase F1 subunit alpha
Synonyms: Mom2, D18Ertd206e, Atp5a1, Atpm
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 11946
HGNC: HGNC:823
Homologene: 2985
Apob
Name: apolipoprotein B
Synonyms: apob-48, apob-100
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Psap
Name: prosaposin
Synonyms: SGP-1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19156
HGNC: HGNC:9498
Homologene: 37680
Eif2ak1
Name: eukaryotic translation initiation factor 2 alpha kinase 1
Synonyms: Hri
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 15467
Homologene: 8290
Gas2l1
Name: growth arrest-specific 2 like 1
Synonyms: TU-71.1, GAR22, 4930500E24Rik, D0Jmb1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 78926
Homologene: 4733
Fam151a
Name: family with sequence simliarity 151, member A
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230579
Homologene: 17143
Kif13a
Name: kinesin family member 13A
Synonyms: 4930505I07Rik, N-3 kinesin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16553
VEGA: 13
Homologene: 22589
Tcf25
Name: transcription factor 25 (basic helix-loop-helix)
Synonyms: 1100001J13Rik, 1810041K11Rik, D8Ertd325e, Nulp1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66855
Homologene: 5701
Usp42
Name: ubiquitin specific peptidase 42
Synonyms: 2410140K03Rik, D5Ertd591e, A630018G05Rik, 3110031A07Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76800
Homologene: 35425
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Ncoa6
Name: nuclear receptor coactivator 6
Synonyms: NRC, ASC-2, PRIP, ASC2, RAP250, AIB3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56406
Homologene: 137337
Lrp4
Name: low density lipoprotein receptor-related protein 4
Synonyms: mdig, 6430526J12Rik, Megf7
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228357
HGNC: HGNC:6696
Homologene: 17964
Tdrd12
Name: tudor domain containing 12
Synonyms: EG434165, 2410004F06Rik, G1-476-14, 2410070K17Rik, repro23, ecat8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71981
Homologene: 87053
Spef2
Name: sperm flagellar 2
Synonyms: C230086A09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 320277
Homologene: 23371
Or4c111
Name: olfactory receptor family 4 subfamily C member 111
Synonyms: MOR233-9, Olfr1216, GA_x6K02T2Q125-50494588-50493653
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258895
Homologene: 74241
Spata31h1
Name: SPATA31 subfamily H member 1
Synonyms: 4932415D10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 102635990
VEGA: 10
Homologene: 82476
Cpeb2
Name: cytoplasmic polyadenylation element binding protein 2
Synonyms: A630055H10Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231207
Homologene: 17995
Lipo3
Name: lipase, member O3
Synonyms: Lipo1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 381236
Homologene: 103863
Zbbx
Name: zinc finger, B-box domain containing
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213234
Homologene: 11661
Ankfn1
Name: ankyrin-repeat and fibronectin type III domain containing 1
Synonyms: mWAKE, LOC382543, nmf9, 4932411E22Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 382543
Homologene: 34996
Or8d1b
Name: olfactory receptor family 8 subfamily D member 1B
Synonyms: MOR171-22, Olfr933, GA_x6K02T2PVTD-32671531-32672457
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258433
VEGA: 9
HGNC: HGNC:8481
Homologene: 79676
Mapk8ip1
Name: mitogen-activated protein kinase 8 interacting protein 1
Synonyms: Skip, Prkm8ip, Jip1, IB1, mjip-2a, MAPK8IP1, JIP-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19099
HGNC: HGNC:6882
Homologene: 31314
Cel
Name: carboxyl ester lipase
Synonyms: 1810036E18Rik, BAL
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12613
HGNC: HGNC:1848
Homologene: 37529
Calhm1
Name: calcium homeostasis modulator 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 546729
VEGA: 19
Homologene: 55508
Pgm1
Name: phosphoglucomutase 1
Synonyms: Pgm2, 2610020G18Rik, Pgm1a, Pgm-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 72157
HGNC: HGNC:8905
Homologene: 1979
Etfrf1
Name: electron transfer flavoprotein regulatory factor 1
Synonyms: Lyrm5, 4930469P12Rik, Ghiso
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67636
Homologene: 44219
Slc47a1
Name: solute carrier family 47, member 1
Synonyms: MATE1, 1300013J15Rik, mMATE1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67473
Homologene: 34364
Otop2
Name: otopetrin 2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237987
Homologene: 27803
Or52z1
Name: olfactory receptor family 52 subfamily Z member 1
Synonyms: Olfr67, 3'[b]1, MOR31-1, GA_x6K02T2PBJ9-6515150-6514170
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18368
Homologene: 85930
Or4a73
Name: olfactory receptor family 4 subfamily A member 73
Synonyms: GA_x6K02T2Q125-51034790-51033846, MOR231-9, Olfr1246
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258788
Homologene: 74246
Mios
Name: meiosis regulator for oocyte development
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 252875
Homologene: 10371
B3galt1
Name: UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
Synonyms: 6330417G03Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26877
HGNC: HGNC:916
Homologene: 41362
Gbp8
Name: guanylate-binding protein 8
Synonyms: 5830443L24Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76074
Zfp677
Name: zinc finger protein 677
Synonyms: A830058L05Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 210503
Homologene: 138402
Sri
Name: sorcin
Synonyms: 2210417O06Rik, 2900070H08Rik, Sor
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 109552
Homologene: 37736
Setbp1
Name: SET binding protein 1
Synonyms: Seb
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240427
Homologene: 9192
Vwa1
Name: von Willebrand factor A domain containing 1
Synonyms: WARP, 4932416A11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 246228
Homologene: 11270
Jrkl
Name: Jrk-like
Synonyms: C030035D04Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 77532
VEGA: 9
HGNC: HGNC:6200
Homologene: 2797
Preb
Name: prolactin regulatory element binding
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 50907
HGNC: HGNC:9356
Homologene: 40877
Leng9
Name: leukocyte receptor cluster (LRC) member 9
Synonyms: 9530024C23Rik, F630035L11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243813
Homologene: 18466
Eif6
Name: eukaryotic translation initiation factor 6
Synonyms: eIF6, p27BBP, Itgb4bp, imc-415
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16418
HGNC: HGNC:6159
Homologene: 7135
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 179,606,535 bp
  • T to G, chromosome 2 at 20,743,805 bp
  • C to A, chromosome 2 at 28,561,202 bp
  • T to C, chromosome 2 at 68,118,546 bp
  • T to C, chromosome 2 at 76,770,600 bp
  • T to A, chromosome 2 at 89,013,204 bp
  • T to C, chromosome 2 at 89,590,579 bp
  • C to A, chromosome 2 at 91,473,580 bp
  • A to G, chromosome 2 at 91,910,317 bp
  • T to C, chromosome 2 at 92,387,182 bp
  • T to A, chromosome 2 at 155,421,428 bp
  • T to C, chromosome 2 at 155,824,008 bp
  • T to C, chromosome 2 at 168,925,827 bp
  • A to T, chromosome 3 at 75,081,817 bp
  • T to C, chromosome 4 at 99,986,757 bp
  • G to T, chromosome 4 at 106,748,109 bp
  • A to T, chromosome 4 at 155,770,363 bp
  • T to C, chromosome 5 at 8,056,625 bp
  • A to G, chromosome 5 at 30,958,852 bp
  • C to A, chromosome 5 at 43,233,828 bp
  • A to G, chromosome 5 at 105,031,258 bp
  • A to G, chromosome 5 at 143,717,985 bp
  • T to C, chromosome 5 at 143,817,793 bp
  • A to T, chromosome 6 at 8,233,221 bp
  • G to A, chromosome 6 at 124,934,371 bp
  • A to T, chromosome 6 at 145,215,427 bp
  • C to T, chromosome 7 at 4,148,667 bp
  • T to C, chromosome 7 at 35,480,269 bp
  • T to A, chromosome 7 at 103,787,948 bp
  • T to C, chromosome 8 at 123,389,709 bp
  • A to G, chromosome 9 at 13,245,333 bp
  • A to T, chromosome 9 at 38,976,125 bp
  • G to T, chromosome 10 at 60,295,958 bp
  • A to G, chromosome 10 at 82,291,111 bp
  • A to G, chromosome 11 at 5,061,497 bp
  • T to G, chromosome 11 at 61,363,098 bp
  • T to G, chromosome 11 at 89,434,757 bp
  • C to A, chromosome 11 at 115,323,639 bp
  • T to C, chromosome 11 at 118,132,316 bp
  • A to T, chromosome 12 at 8,008,046 bp
  • G to T, chromosome 13 at 46,788,060 bp
  • T to A, chromosome 14 at 103,242,360 bp
  • G to T, chromosome 15 at 9,113,733 bp
  • A to G, chromosome 15 at 9,601,631 bp
  • T to C, chromosome 15 at 85,391,717 bp
  • T to G, chromosome 17 at 21,392,553 bp
  • T to C, chromosome 17 at 32,122,718 bp
  • C to T, chromosome 18 at 77,778,759 bp
  • A to G, chromosome 18 at 78,857,051 bp
  • T to A, chromosome 19 at 15,978,954 bp
  • A to C, chromosome 19 at 33,780,314 bp
  • A to T, chromosome 19 at 47,141,389 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9062 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068888-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.