Strain Name:
C57BL/6J-MtgxR9120Btlr/Mmmh
Stock Number:
068923-MU
Citation ID:
RRID:MMRRC_068923-MU
Other Names:
R9120 (G1)
Major Collection:

Strain Information

Snx17
Name: sorting nexin 17
Synonyms: b2b1625.1Clo, D5Ertd260e, 5830447M19Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 266781
Homologene: 8838
Rgs14
Name: regulator of G-protein signaling 14
Synonyms: Rap1/rap2 interacting protein
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 51791
HGNC: HGNC:9996
Homologene: 4735
Spen
Name: spen family transcription repressor
Synonyms: Mint
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56381
Homologene: 124461
Ddx1
Name: DEAD box helicase 1
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104721
VEGA: 12
HGNC: HGNC:2734
Homologene: 3627
Tyw1
Name: tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
Synonyms: Rsafd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100929
Homologene: 7068
Fndc3a
Name: fibronectin type III domain containing 3A
Synonyms: 1700094E19Rik, F730017H24Rik, Fndc3, D14Ertd453e, sys
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 319448
Homologene: 8952
Mdn1
Name: midasin AAA ATPase 1
Synonyms: 4833432B22Rik, LOC213784, D4Abb1e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100019
Homologene: 39689
Tacc1
Name: transforming, acidic coiled-coil containing protein 1
Synonyms: 4833447E04Rik, Tacc1, B230378H13Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 320165
Homologene: 4575
Tmem135
Name: transmembrane protein 135
Synonyms: 2810439K08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 72759
Homologene: 11295
Bicc1
Name: BicC family RNA binding protein 1
Synonyms: Bic-C, jcpk
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 83675
Homologene: 12856
Adgrb2
Name: adhesion G protein-coupled receptor B2
Synonyms: Bai2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230775
HGNC: HGNC:944
Homologene: 1288
Mpzl2
Name: myelin protein zero-like 2
Synonyms: Eva1, Eva
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14012
HGNC: HGNC:3496
Homologene: 7309
Kazald1
Name: Kazal-type serine peptidase inhibitor domain 1
Synonyms: Bono1, Igfbp-rp10
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107250
Homologene: 12799
Map2
Name: microtubule-associated protein 2
Synonyms: MAP-2, G1-397-34, repro4, Mtap2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Zfp57
Name: zinc finger protein 57
Synonyms: G19
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22715
Homologene: 7603
Zfp148
Name: zinc finger protein 148
Synonyms: ZBP-89, BFCOL1, BERF-1, 2210405J08Rik, beta enolase repressor factor 1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 22661
VEGA: 16
Homologene: 8003
Plod2
Name: procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
Synonyms: LH2, D530025C14Rik, Plod-2, lysyl hydroxylase 2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 26432
HGNC: HGNC:9082
Homologene: 22681
Bpifb1
Name: BPI fold containing family B, member 1
Synonyms: U46068, von Ebner minor salivary protein, LPlunc1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228801
Homologene: 50047
Dlk1
Name: delta like non-canonical Notch ligand 1
Synonyms: ZOG, SCP1, FA1, DlkI, pG2, pref-1, Peg9
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13386
HGNC: HGNC:2907
Homologene: 2846
Jag1
Name: jagged 1
Synonyms: Serrate-1, Headturner, Ozz, Htu, Gsfabe2, ABE2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16449
HGNC: HGNC:6188
Homologene: 180
Trmt2a
Name: TRM2 tRNA methyltransferase 2A
Synonyms: Htf9c
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 15547
Homologene: 7374
Col9a2
Name: collagen, type IX, alpha 2
Synonyms: Col9a-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12840
HGNC: HGNC:2218
Homologene: 37535
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Myo3a
Name: myosin IIIA
Synonyms: 9030416P08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 667663
HGNC: HGNC:7601
Homologene: 49486
Magi2
Name: membrane associated guanylate kinase, WW and PDZ domain containing 2
Synonyms: S-SCAM, Acvrinp1, Magi-2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 50791
Homologene: 8189
Gsap
Name: gamma-secretase activating protein
Synonyms: A530088I07Rik, Pion
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 212167
Homologene: 45504
Btnl1
Name: butyrophilin-like 1
Synonyms: NG10, LOC240074, LOC240074, Btnl3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 100038862
Homologene: 103816
Ripor3
Name: RIPOR family member 3
Synonyms: 2310033K02Rik, Fam65c
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69553
Homologene: 15438
Adam25
Name: ADAM metallopeptidase domain 25
Synonyms: testase 2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23793
HGNC: HGNC:199
Homologene: 128364
Rnf139
Name: ring finger protein 139
Synonyms: 4930555P18Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75841
VEGA: 15
Homologene: 5222
Dgkz
Name: diacylglycerol kinase zeta
Synonyms: mDGK[z], E130307B02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 104418
HGNC: HGNC:2857
Homologene: 37831
Rin1
Name: Ras and Rab interactor 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225870
VEGA: 19
Homologene: 3170
Lrrcc1
Name: leucine rich repeat and coiled-coil domain containing 1
Synonyms: 4932441F23Rik, 1200008A14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71710
Homologene: 12559
Or1j4
Name: olfactory receptor family 1 subfamily J member 4
Synonyms: Olfr350, GA_x6K02T2NLDC-33544602-33545540, MOR136-13
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258620
HGNC: HGNC:8211
Homologene: 64897
Wdr27
Name: WD repeat domain 27
Synonyms: 0610012K18Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71682
VEGA: 17
Homologene: 18417
Pgap4
Name: post-GPI attachment to proteins GalNAc transferase 4
Synonyms: Tmem246, 9330170P15Rik, 2810432L12Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67063
Homologene: 12080
Ldhb
Name: lactate dehydrogenase B
Synonyms: lactate dehydrogenase-B, Ldh-2, H-Ldh
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16832
HGNC: HGNC:6541
Homologene: 55647
D7Ertd443e
Name: DNA segment, Chr 7, ERATO Doi 443, expressed
Synonyms: 4933400E14Rik, Fats
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71007
Homologene: 18998
Spaca1
Name: sperm acrosome associated 1
Synonyms: 4930540L03Rik, 1700124L11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67652
Homologene: 12170
Vmn2r86
Name: vomeronasal 2, receptor 86
Synonyms: EG625109
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 625109
Homologene: 129606
Mtif2
Name: mitochondrial translational initiation factor 2
Synonyms: 2410112O06Rik, IF-2mt, 2310038D14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76784
HGNC: HGNC:7441
Homologene: 1840
BC051665
Name: cDNA sequence BC051665
Synonyms: cathepsin L-like
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218275
VEGA: 13
Homologene: 74298
Arhgap24
Name: Rho GTPase activating protein 24
Synonyms: 0610025G21Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231532
Homologene: 32754
Or5p6
Name: olfactory receptor family 5 subfamily P member 6
Synonyms: Olfr478, GA_x6K02T2PBJ9-10361879-10360935, MOR204-13
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258729
Homologene: 128076
Trim63
Name: tripartite motif-containing 63
Synonyms: MuRF1, Rnf28
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 433766
Homologene: 41878
Or10ac1
Name: olfactory receptor family 10 subfamily AC member 1
Synonyms: EG546896, Olfr455-ps1, Olfr455, MORO-2, GA_x6K02T2P3E9-5021913-5022918, MOR0-2P, MOR0-17_p
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 546896
Homologene: 67366
Or5d38
Name: olfactory receptor family 5 subfamily D member 38
Synonyms: GA_x6K02T2Q125-49616865-49615915, Olfr1166, MOR174-6
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258644
Homologene: 138307
Vmn1r211
Name: vomeronasal 1 receptor 211
Synonyms: V1rh20
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171277
Homologene: 110880
Or8g51
Name: olfactory receptor family 8 subfamily G member 51
Synonyms: Olfr919, GA_x6K02T2PVTD-32400678-32399743, MOR171-23
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258432
VEGA: 9
Gm28042
Name: predicted gene, 28042
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 102238433
Castor1
Name: cytosolic arginine sensor for mTORC1 subunit 1
Synonyms: 2410008K03Rik, Gatsl3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71962
Homologene: 81920
BC030500
Name: cDNA sequence BC030500
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234290
Dchs2
Name: dachsous cadherin related 2
Synonyms: LOC229459
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 100534287
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 66,414,059 bp
  • T to C, chromosome 2 at 22,544,426 bp
  • T to A, chromosome 2 at 36,850,131 bp
  • T to C, chromosome 2 at 76,938,372 bp
  • A to G, chromosome 2 at 88,124,779 bp
  • G to T, chromosome 2 at 91,938,200 bp
  • C to T, chromosome 2 at 120,038,981 bp
  • A to T, chromosome 2 at 137,088,434 bp
  • A to G, chromosome 2 at 154,204,772 bp
  • T to C, chromosome 2 at 167,980,915 bp
  • C to T, chromosome 3 at 14,550,429 bp
  • A to T, chromosome 3 at 83,280,228 bp
  • A to T, chromosome 4 at 32,701,814 bp
  • A to G, chromosome 4 at 34,029,168 bp
  • A to G, chromosome 4 at 49,587,093 bp
  • G to T, chromosome 4 at 121,043,754 bp
  • A to G, chromosome 4 at 130,012,509 bp
  • G to A, chromosome 4 at 134,327,692 bp
  • G to T, chromosome 4 at 141,472,922 bp
  • A to T, chromosome 5 at 20,528,307 bp
  • A to G, chromosome 5 at 21,253,436 bp
  • A to G, chromosome 5 at 31,197,682 bp
  • A to T, chromosome 5 at 102,892,150 bp
  • G to A, chromosome 5 at 130,269,224 bp
  • A to C, chromosome 6 at 42,538,649 bp
  • A to G, chromosome 6 at 142,494,209 bp
  • G to C, chromosome 7 at 89,147,978 bp
  • T to C, chromosome 7 at 108,031,680 bp
  • T to A, chromosome 7 at 134,270,257 bp
  • G to T, chromosome 8 at 25,169,239 bp
  • A to G, chromosome 8 at 40,756,104 bp
  • T to A, chromosome 8 at 58,912,877 bp
  • A to G, chromosome 9 at 38,697,439 bp
  • T to A, chromosome 9 at 45,047,285 bp
  • G to T, chromosome 9 at 92,542,327 bp
  • T to C, chromosome 10 at 70,941,032 bp
  • T to G, chromosome 10 at 130,453,808 bp
  • T to A, chromosome 11 at 4,220,767 bp
  • T to C, chromosome 11 at 29,533,951 bp
  • A to G, chromosome 12 at 13,225,457 bp
  • A to G, chromosome 12 at 109,458,125 bp
  • A to T, chromosome 13 at 22,851,766 bp
  • A to C, chromosome 13 at 55,380,979 bp
  • A to G, chromosome 13 at 60,785,102 bp
  • A to G, chromosome 14 at 72,564,693 bp
  • T to C, chromosome 15 at 58,899,836 bp
  • C to A, chromosome 16 at 18,249,858 bp
  • A to G, chromosome 16 at 33,497,226 bp
  • A to G, chromosome 17 at 14,932,584 bp
  • A to T, chromosome 17 at 34,379,707 bp
  • G to A, chromosome 17 at 37,009,758 bp
  • C to A, chromosome 19 at 5,053,020 bp
  • A to T, chromosome 19 at 45,076,772 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9120 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068923-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.