Strain Name:
C57BL/6J-MtgxR0099Btlr/Mmmh
Stock Number:
038385-MU
Citation ID:
RRID:MMRRC_038385-MU
Other Names:
R0099 (G1), C57BL/6J-MtgxR0099Btlr
Major Collection:

Gene Information

Gli1
Name: GLI-Kruppel family member GLI1
Synonyms: Zfp5, Zfp-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14632
VEGA: 10
HGNC: HGNC:4317
Homologene: 3859
Phf14
Name: PHD finger protein 14
Synonyms: 5730446A07Rik, 1110001C23Rik, 4932409F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 75725
VEGA: 6
Homologene: 8775
Sgsm1
Name: small G protein signaling modulator 1
Synonyms: D5Bwg1524e, 2410098H20Rik, Rutbc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 52850
VEGA: 5
Homologene: 64485
Ube3c
Name: ubiquitin protein ligase E3C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100763
VEGA: 5
Homologene: 8783
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: Murr2, A530081C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17847
VEGA: 11
Homologene: 40978
Rfc2
Name: replication factor C (activator 1) 2
Synonyms: Recc2, 2610008M13Rik, 40kDa, 40kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19718
VEGA: 5
HGNC: HGNC:9970
Homologene: 6885
Utp25
Name: UTP25 small subunit processome component
Synonyms: Diexf, AA408296
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 215193
VEGA: 1
Homologene: 6170
Polr2b
Name: polymerase (RNA) II (DNA directed) polypeptide B
Synonyms: RPB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231329
VEGA: 5
HGNC: HGNC:9188
Homologene: 722
Nol8
Name: nucleolar protein 8
Synonyms: 4921532D18Rik, 5730412B09Rik, D13Ertd548e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 70930
VEGA: 13
Homologene: 41210
Dsg3
Name: desmoglein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13512
VEGA: 18
HGNC: HGNC:3050
Homologene: 55513
Col4a3
Name: collagen, type IV, alpha 3
Synonyms: alpha3(IV), tumstatin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12828
VEGA: 1
HGNC: HGNC:2204
Homologene: 68033
Prdm14
Name: PR domain containing 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 383491
VEGA: 1
Homologene: 11556
Sycp2l
Name: synaptonemal complex protein 2-like
Synonyms: LOC218175, Gm40956, EG621792
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 637277
VEGA: 13
Homologene: 52882
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: 4930545D19Rik, hy-3, hy3, 1700034M11Rik, hyrh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244653
VEGA: 8
Homologene: 52118
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b1537Clo, b2b1565Clo, b2b3491Clo, b2b1154Clo, Mdnah5, Dnahc5, b2b1134Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 110082
VEGA: 15
HGNC: HGNC:2950
Homologene: 1048
Acad10
Name: acyl-Coenzyme A dehydrogenase family, member 10
Synonyms: 2410021P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71985
VEGA: 5
Homologene: 49825
Col11a2
Name: collagen, type XI, alpha 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12815
VEGA: 17
HGNC: HGNC:2187
Homologene: 22547
Plekhh2
Name: pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 213556
VEGA: 17
Homologene: 35317
Myo3a
Name: myosin IIIA
Synonyms: 9030416P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 667663
VEGA: 2
HGNC: HGNC:7601
Homologene: 49486
Astn1
Name: astrotactin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11899
VEGA: 1
HGNC: HGNC:773
Homologene: 7233
Tril
Name: TLR4 interactor with leucine-rich repeats
Synonyms: 1200009O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 66873
VEGA: 6
Homologene: 69404
Olfr1458
Name: olfactory receptor 1458
Synonyms: MOR202-24, EG667271, GA_x6K02T2RE5P-3430689-3429787
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 667271
VEGA: 19
Rabgap1l
Name: RAB GTPase activating protein 1-like
Synonyms: 5830411O09Rik, 8430421H08Rik, Hh1, 9630005B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 29809
VEGA: 1
Homologene: 8143
Fras1
Name: Fraser extracellular matrix complex subunit 1
Synonyms: E130113P14Rik, bl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231470
VEGA: 5
Homologene: 23516
Stpg2
Name: sperm tail PG rich repeat containing 2
Synonyms: B930007M17Rik, LOC381476
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 381476
VEGA: 3
Homologene: 52167
Skint6
Name: selection and upkeep of intraepithelial T cells 6
Synonyms: OTTMUSG00000008519
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230622
VEGA: 4
Homologene: 135888
Slc15a2
Name: solute carrier family 15 (H+/peptide transporter), member 2
Synonyms: 8430408C16Rik, Pept2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 57738
VEGA: 16
Homologene: 56912
Cstf2t
Name: cleavage stimulation factor, 3' pre-RNA subunit 2, tau
Synonyms: 64kDa, tCstF-64
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 83410
VEGA: 19
Homologene: 80230
Krt81
Name: keratin 81
Synonyms: Krt2-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 64818
VEGA: 15
HGNC: HGNC:6458
Homologene: 55645
Micall1
Name: microtubule associated monooxygenase, calponin and LIM domain containing -like 1
Synonyms: D15Mit260, D15N2e, Mus EST 820961
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 27008
VEGA: 15
Homologene: 24911
Myh4
Name: myosin, heavy polypeptide 4, skeletal muscle
Synonyms: MYH-2B, Minmus, Minimsc, Myhsf, MM, MyHC-IIb, MHC2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17884
VEGA: 11
HGNC: HGNC:7574
Homologene: 123880
Mthfs
Name: 5, 10-methenyltetrahydrofolate synthetase
Synonyms: 1110034I12Rik, 2310020H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 107885
VEGA: 9
Homologene: 4702
Kynu
Name: kynureninase
Synonyms: 4432411A05Rik, L-kynurenine hydrolase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 70789
VEGA: 2
HGNC: HGNC:6469
Homologene: 2925
Pde1a
Name: phosphodiesterase 1A, calmodulin-dependent
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18573
VEGA: 2
HGNC: HGNC:8774
Homologene: 21043
C130079G13Rik
Name: RIKEN cDNA C130079G13 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229333
VEGA: 3
Adamtsl4
Name: ADAMTS-like 4
Synonyms: Tsrc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229595
VEGA: 3
Homologene: 23141
Manea
Name: mannosidase, endo-alpha
Synonyms: 4932703L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242362
VEGA: 4
Homologene: 11636
Cyp4a12a
Name: cytochrome P450, family 4, subfamily a, polypeptide 12a
Synonyms: Cyp4a12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 277753
VEGA: 4
Homologene: 134044
Fam76a
Name: family with sequence similarity 76, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230789
VEGA: 4
Homologene: 27071
Ica1
Name: islet cell autoantigen 1
Synonyms: ICA69, 69kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 15893
VEGA: 6
HGNC: HGNC:5343
Homologene: 7777
Irf5
Name: interferon regulatory factor 5
Synonyms: mirf5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 27056
VEGA: 6
HGNC: HGNC:6120
Homologene: 8088
Zfp93
Name: zinc finger protein 93
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22755
VEGA: 7
Homologene: 117959
Olfr151
Name: olfactory receptor 151
Synonyms: M71, GA_x6K02T2PVTD-31408136-31407207, MOR171-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 406176
VEGA: 9
HGNC: HGNC:8469
Homologene: 12726
Olfr967
Name: olfactory receptor 967
Synonyms: MOR171-30P, GA_x6K02T2PVTD-33447884-33448816
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258086
VEGA: 9
HGNC: HGNC:8484
Homologene: 115535
Rgs17
Name: regulator of G-protein signaling 17
Synonyms: RGSZ2, 6430507P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 56533
VEGA: 10
Homologene: 8242
Nepn
Name: nephrocan
Synonyms: Npn, 5730521E12Rik, periolin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 66650
VEGA: 10
Homologene: 23549
Rfx4
Name: regulatory factor X, 4 (influences HLA class II expression)
Synonyms: 4933412G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71137
VEGA: 10
HGNC: HGNC:9985
Homologene: 31119
Ikzf4
Name: IKAROS family zinc finger 4
Synonyms: A630026H08Rik, Zfpn1a4, Eos
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 22781
VEGA: 10
Homologene: 69103
Ppp1r36
Name: protein phosphatase 1, regulatory subunit 36
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 210762
VEGA: 12
Homologene: 52094
Gm10782
Name: predicted gene 10782
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 100038494
VEGA: 13
Tlr11
Name: toll-like receptor 11
Synonyms: LOC239081
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239081
VEGA: 14
Homologene: 77905
A930018M24Rik
Name: RIKEN cDNA A930018M24 gene
Synonyms: LOC382890
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
Rnf139
Name: ring finger protein 139
Synonyms: 4930555P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 75841
VEGA: 15
Homologene: 5222
Ly6g6c
Name: lymphocyte antigen 6 complex, locus G6C
Synonyms: 1110003M04Rik, G6c, NG24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 68468
VEGA: 17
Homologene: 11350
Greb1l
Name: growth regulation by estrogen in breast cancer-like
Synonyms: mKIAA4095, AK220484
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 381157
VEGA: 18
Homologene: 73393
Atg2a
Name: autophagy related 2A
Synonyms: 1810013C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 329015
VEGA: 19
Homologene: 86985
Olfr1453
Name: olfactory receptor 1453
Synonyms: GA_x6K02T2RE5P-3357666-3356743, MOR202-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258695
VEGA: 19
Homologene: 120159
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 13,118,945 bp
  • A to C, chromosome 1 at 82,717,993 bp
  • G to T, chromosome 1 at 158,502,151 bp
  • A to G, chromosome 1 at 160,682,116 bp
  • A to G, chromosome 1 at 193,128,470 bp
  • T to C, chromosome 2 at 22,245,598 bp
  • T to A, chromosome 2 at 43,629,053 bp
  • T to A, chromosome 2 at 79,868,313 bp
  • A to C, chromosome 3 at 59,936,435 bp
  • C to T, chromosome 3 at 95,684,139 bp
  • T to C, chromosome 3 at 139,243,193 bp
  • A to C, chromosome 4 at 26,328,104 bp
  • T to A, chromosome 4 at 112,811,501 bp
  • T to C, chromosome 4 at 115,326,672 bp
  • G to T, chromosome 4 at 132,910,787 bp
  • T to A, chromosome 5 at 29,607,064 bp
  • T to A, chromosome 5 at 77,320,950 bp
  • T to A, chromosome 5 at 96,614,917 bp
  • C to A, chromosome 5 at 113,274,360 bp
  • A to C, chromosome 5 at 121,621,290 bp
  • A to T, chromosome 5 at 134,595,281 bp
  • A to T, chromosome 6 at 8,749,778 bp
  • A to G, chromosome 6 at 11,987,697 bp
  • A to G, chromosome 6 at 29,533,967 bp
  • A to G, chromosome 6 at 53,818,363 bp
  • G to T, chromosome 7 at 24,275,475 bp
  • G to A, chromosome 8 at 110,589,561 bp
  • A to T, chromosome 9 at 37,711,454 bp
  • A to G, chromosome 9 at 39,750,661 bp
  • A to T, chromosome 9 at 89,226,163 bp
  • T to A, chromosome 10 at 5,842,583 bp
  • A to G, chromosome 10 at 52,401,085 bp
  • A to T, chromosome 10 at 84,894,304 bp
  • A to G, chromosome 10 at 127,336,006 bp
  • T to A, chromosome 10 at 128,634,197 bp
  • G to A, chromosome 11 at 23,363,111 bp
  • A to G, chromosome 11 at 67,259,347 bp
  • G to T, chromosome 12 at 76,436,282 bp
  • T to C, chromosome 13 at 41,129,525 bp
  • T to C, chromosome 13 at 49,672,689 bp
  • T to A, chromosome 13 at 56,363,143 bp
  • A to T, chromosome 14 at 50,360,818 bp
  • C to T, chromosome 14 at 50,896,722 bp
  • G to A, chromosome 15 at 28,239,934 bp
  • C to A, chromosome 15 at 58,899,415 bp
  • G to T, chromosome 15 at 79,131,901 bp
  • A to T, chromosome 15 at 101,463,521 bp
  • T to C, chromosome 16 at 36,753,036 bp
  • A to G, chromosome 17 at 34,049,674 bp
  • T to C, chromosome 17 at 35,068,915 bp
  • C to T, chromosome 17 at 84,591,672 bp
  • A to G, chromosome 18 at 10,509,158 bp
  • A to G, chromosome 18 at 20,540,022 bp
  • T to A, chromosome 19 at 6,252,789 bp
  • A to G, chromosome 19 at 13,027,801 bp
  • T to A, chromosome 19 at 13,103,140 bp
  • A to G, chromosome 19 at 31,083,831 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0099 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038385-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.