Strain Name:
C57BL/6J-MtgxR2135Btlr/Mmmh
Stock Number:
040138-MU
Citation ID:
RRID:MMRRC_040138-MU
Other Names:
R2135 (G1), C57BL/6J-MtgxR2135Btlr
Major Collection:

Gene Information

Ext1
Name: exostoses (multiple) 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 14042
HGNC: HGNC:3512
Homologene: 30957
Atm
Name: ataxia telangiectasia mutated
Synonyms: C030026E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 11920
HGNC: HGNC:795
Homologene: 30952
Timmdc1
Name: translocase of inner mitochondrial membrane domain containing 1
Synonyms: 4930455C21Rik, 2810021C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 76916
HGNC: HGNC:1321
Homologene: 9578
Msra
Name: methionine sulfoxide reductase A
Synonyms: 6530413P12Rik, 2310045J23Rik, MSR-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 110265
HGNC: HGNC:7377
Homologene: 5812
L3mbtl2
Name: L3MBTL2 polycomb repressive complex 1 subunit
Synonyms: m4mbt, 4732493N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 214669
Homologene: 12882
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Phr1, C130061D10Rik, Pam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105689
Homologene: 9005
Ltn1
Name: listerin E3 ubiquitin protein ligase 1
Synonyms: Zfp294, 4930528H02Rik, Rnf160, Listerin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 78913
VEGA: 16
Homologene: 32272
Commd10
Name: COMM domain containing 10
Synonyms: 2310003A05Rik, DRWMS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 69456
VEGA: 18
Homologene: 9404
Nsrp1
Name: nuclear speckle regulatory protein 1
Synonyms: NSpr70, Ccdc55
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237859
Homologene: 134095
Rp9
Name: retinitis pigmentosa 9 (human)
Synonyms: Rp9h, PAP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 55934
VEGA: 9
Homologene: 10290
Akap9
Name: A kinase (PRKA) anchor protein (yotiao) 9
Synonyms: mei2-5, G1-448-15, 5730481H23Rik, AKAP450, repro12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Tasor
Name: transcription activation suppressor
Synonyms: D14Abb1e, 4933409E02Rik, MommeD6, Fam208a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 218850
VEGA: 14
Homologene: 9062
Plekha5
Name: pleckstrin homology domain containing, family A member 5
Synonyms: Ayu21-9, Gt(Ayu21)9Imeg, AMH-Cre, PEPP2, 2810431N21Rik, Tg(AMH-cre)1Flor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 109135
Homologene: 10377
Dock4
Name: dedicator of cytokinesis 4
Synonyms: EST N28122, 6330411N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238130
VEGA: 12
Homologene: 56680
Slc25a40
Name: solute carrier family 25, member 40
Synonyms: B230315F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 319653
Homologene: 6040
Gucy2c
Name: guanylate cyclase 2c
Synonyms: GC-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14917
HGNC: HGNC:4688
Homologene: 3641
Sla
Name: src-like adaptor
Synonyms: Slap-1, Slap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 20491
Homologene: 36206
Cecr2
Name: CECR2, histone acetyl-lysine reader
Synonyms: Gtl4, cat eye syndrome chromosome region, candidate 2, 2610101O16Rik, 2810409N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330409
HGNC: HGNC:1840
Homologene: 64662
Ncr1
Name: natural cytotoxicity triggering receptor 1
Synonyms: MAR1 (mouse activating receptor 1), Ly94, NKp46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17086
HGNC: HGNC:6731
Homologene: 3551
4930522L14Rik
Name: RIKEN cDNA 4930522L14 gene
Synonyms: Gm42152
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100041734
Klrk1
Name: killer cell lectin-like receptor subfamily K, member 1
Synonyms: Nkg2d, NKG2-D, D6H12S2489E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 27007
Homologene: 7209
Slc3a2
Name: solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
Synonyms: Mdu1, Mgp-2hc, Cd98, 4F2HC, Ly-m10, Ly-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 17254
Homologene: 1795
Lsm14a
Name: LSM14A mRNA processing body assembly factor
Synonyms: 2700023B17Rik, Tral
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67070
Homologene: 40537
Zcrb1
Name: zinc finger CCHC-type and RNA binding motif 1
Synonyms: 2700088M22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 67197
Homologene: 12095
Zfyve26
Name: zinc finger, FYVE domain containing 26
Synonyms: A630028O16Rik, LOC380767, 9330197E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 211978
VEGA: 12
Homologene: 9102
Frmd6
Name: FERM domain containing 6
Synonyms: 4930488L10Rik, 2610019M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319710
VEGA: 12
Homologene: 12449
March6
Name: membrane-associated ring finger (C3HC4) 6
Synonyms: F830029L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223455
VEGA: 15
Homologene: 4301
Kdm4a
Name: lysine (K)-specific demethylase 4A
Synonyms: D4Ertd222e, Jmjd2a, Jmjd2, JHDM3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230674
Homologene: 27780
Slc7a5
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
Synonyms: LAT1, D0H16S474E, TA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 20539
Homologene: 55759
Sec31b
Name: Sec31 homolog B (S. cerevisiae)
Synonyms: Sec31l2, LOC240667
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 240667
Homologene: 56708
Cacna2d2
Name: calcium channel, voltage-dependent, alpha 2/delta subunit 2
Synonyms: a2d2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 56808
HGNC: HGNC:1400
Homologene: 4400
Cfap74
Name: cilia and flagella associated protein 74
Synonyms: 2010015L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 544678
Homologene: 129584
Arap3
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Synonyms: E030006K04Rik, Centd3, DRAG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 106952
VEGA: 18
Homologene: 11199
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: D12Ertd777e, Nesp2g, nesprin-2, syne-2, dice, Cpfl8, 6820443O06Rik, diminished cone electroretinogram
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319565
Homologene: 56700
Tecta
Name: tectorin alpha
Synonyms: Tctna, [a]-tectorin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 21683
Homologene: 3955
Pkdrej
Name: polycystin (PKD) family receptor for egg jelly
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18766
VEGA: 15
HGNC: HGNC:9015
Homologene: 4427
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 329628
Homologene: 14377
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: VLGR1, Mgr1, Mass1, Gpr98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 110789
Homologene: 19815
Ptchd4
Name: patched domain containing 4
Synonyms: 3110082D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 627626
VEGA: 17
Homologene: 78322
Tmem30b
Name: transmembrane protein 30B
Synonyms: 9130011B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238257
VEGA: 12
Homologene: 133755
Cdhr2
Name: cadherin-related family member 2
Synonyms: Pcdh24, LOC268663
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 268663
Homologene: 134510
Adamts16
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 271127
Homologene: 15146
Ermp1
Name: endoplasmic reticulum metallopeptidase 1
Synonyms: D19Wsu12e, D19Ertd410e, b2b2633Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226090
Homologene: 121891
Ripk4
Name: receptor-interacting serine-threonine kinase 4
Synonyms: Ankrd3, DIk, PKK, RIP4, ANKK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 72388
HGNC: HGNC:496
Homologene: 10772
Gm11437
Name: predicted gene 11437
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 628813
Homologene: 82346
Shank2
Name: SH3 and multiple ankyrin repeat domains 2
Synonyms: ProSAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 210274
Homologene: 105965
Tmem94
Name: transmembrane protein 94
Synonyms: 2310067B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71947
Homologene: 8831
Slco6c1
Name: solute carrier organic anion transporter family, member 6c1
Synonyms: 4933404A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74441
Homologene: 65259
Naaladl1
Name: N-acetylated alpha-linked acidic dipeptidase-like 1
Synonyms: LOC381204
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 381204
Homologene: 21124
Ces5a
Name: carboxylesterase 5A
Synonyms: Ces7, LOC244598, 1700122C07Rik, cauxin, 1700081L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 67935
Homologene: 74305
CK137956
Name: cDNA sequence CK137956
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 635169
Homologene: 57187
Ankrd2
Name: ankyrin repeat domain 2 (stretch responsive muscle)
Synonyms: Arpp, mArpp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 56642
VEGA: 19
HGNC: HGNC:495
Homologene: 10568
Olfr873
Name: olfactory receptor 873
Synonyms: GA_x6K02T2PVTD-14040245-14041204, MOR145-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258554
HGNC: HGNC:8396
Homologene: 115528
Rbsn
Name: rabenosyn, RAB effector
Synonyms: Rabenosyn-5, 5330426D11Rik, Zfyve20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 78287
Homologene: 41477
Kcnt2
Name: potassium channel, subfamily T, member 2
Synonyms: E330038N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240776
Homologene: 16121
Vcpip1
Name: valosin containing protein (p97)/p47 complex interacting protein 1
Synonyms: Vcip135, 5730538E15Rik, 5730421J18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 70675
Homologene: 11814
Ppp2r3a
Name: protein phosphatase 2, regulatory subunit B'', alpha
Synonyms: 3222402P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235542
HGNC: HGNC:9307
Homologene: 20595
Idh1
Name: isocitrate dehydrogenase 1 (NADP+), soluble
Synonyms: IDPc, Idh-1, Id-1, E030024J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 15926
HGNC: HGNC:5382
Homologene: 21195
Nkd1
Name: naked cuticle 1
Synonyms: 9030215G15Rik, 2810434J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 93960
Homologene: 12343
Cfb
Name: complement factor B
Synonyms: alternative-complement pathway C3/C5 convertase, Bf, FB, Factor B, H2-Bf, B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14962
HGNC: HGNC:1037
Homologene: 1292
Vmn2r76
Name: vomeronasal 2, receptor 76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 675969
Homologene: 104330
Tktl2
Name: transketolase-like 2
Synonyms: 4933401I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74419
Homologene: 69456
Prima1
Name: proline rich membrane anchor 1
Synonyms: B230212M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 170952
Homologene: 15783
Rasgrf2
Name: RAS protein-specific guanine nucleotide-releasing factor 2
Synonyms: Grf2, 6330417G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 19418
HGNC: HGNC:9876
Homologene: 2169
Prdm12
Name: PR domain containing 12
Synonyms: LOC381359
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 381359
Homologene: 10999
9230110F15Rik
Name: RIKEN cDNA 9230110F15 gene
Synonyms:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
Fscn3
Name: fascin actin-bundling protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 56223
HGNC: HGNC:3961
Homologene: 10475
Tshb
Name: thyroid stimulating hormone, beta subunit
Synonyms: thyrotropin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 22094
Homologene: 463
Mocs2
Name: molybdenum cofactor synthesis 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17434
HGNC: HGNC:7193
Homologene: 32193
Olfr330
Name: olfactory receptor 330
Synonyms: MOR275-1, GA_x6K02T2NKPP-895420-896349
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258879
Homologene: 133015
Gbx1
Name: gastrulation brain homeobox 1
Synonyms: Gbx-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231044
HGNC: HGNC:4185
Homologene: 41063
Smim10l1
Name: small integral membrane protein 10 like 1
Synonyms: 2700089E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 381820
Homologene: 130035
Cox6c
Name: cytochrome c oxidase subunit 6C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12864
HGNC: HGNC:2285
Homologene: 134053
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 9,747,810 bp
  • A to C, chromosome 1 at 65,161,919 bp
  • A to G, chromosome 1 at 97,104,817 bp
  • A to G, chromosome 1 at 140,428,813 bp
  • T to C, chromosome 2 at 31,640,313 bp
  • A to T, chromosome 3 at 38,980,733 bp
  • A to G, chromosome 3 at 102,778,148 bp
  • A to G, chromosome 4 at 118,142,459 bp
  • A to G, chromosome 4 at 127,951,640 bp
  • C to G, chromosome 4 at 155,429,940 bp
  • T to A, chromosome 4 at 155,429,951 bp
  • A to G, chromosome 5 at 4,064,509 bp
  • A to G, chromosome 5 at 8,427,489 bp
  • G to T, chromosome 5 at 24,526,222 bp
  • A to T, chromosome 5 at 109,737,643 bp
  • A to G, chromosome 6 at 28,431,584 bp
  • T to A, chromosome 6 at 92,189,873 bp
  • C to T, chromosome 6 at 120,720,962 bp
  • A to G, chromosome 6 at 129,622,526 bp
  • T to C, chromosome 6 at 133,105,526 bp
  • T to A, chromosome 6 at 136,723,728 bp
  • T to A, chromosome 6 at 140,580,499 bp
  • C to A, chromosome 7 at 4,340,757 bp
  • A to G, chromosome 7 at 34,371,184 bp
  • A to G, chromosome 7 at 86,231,011 bp
  • C to T, chromosome 7 at 144,411,234 bp
  • G to A, chromosome 8 at 66,512,347 bp
  • T to C, chromosome 8 at 88,591,650 bp
  • C to A, chromosome 8 at 93,499,741 bp
  • A to T, chromosome 8 at 121,883,705 bp
  • T to A, chromosome 9 at 20,300,297 bp
  • T to C, chromosome 9 at 22,468,129 bp
  • A to C, chromosome 9 at 35,839,183 bp
  • A to C, chromosome 9 at 42,340,285 bp
  • A to C, chromosome 9 at 53,450,503 bp
  • A to C, chromosome 9 at 101,211,558 bp
  • C to A, chromosome 9 at 107,526,513 bp
  • A to C, chromosome 11 at 58,529,785 bp
  • A to T, chromosome 11 at 77,055,008 bp
  • T to C, chromosome 11 at 84,153,812 bp
  • A to G, chromosome 11 at 115,794,749 bp
  • A to G, chromosome 12 at 40,745,668 bp
  • A to G, chromosome 12 at 70,894,997 bp
  • A to G, chromosome 12 at 73,545,333 bp
  • A to G, chromosome 12 at 75,952,786 bp
  • T to C, chromosome 12 at 79,246,052 bp
  • A to T, chromosome 12 at 103,202,690 bp
  • T to A, chromosome 13 at 54,720,947 bp
  • C to A, chromosome 13 at 70,801,007 bp
  • A to G, chromosome 13 at 81,524,557 bp
  • G to A, chromosome 13 at 91,972,255 bp
  • T to G, chromosome 13 at 114,826,296 bp
  • A to G, chromosome 14 at 27,448,140 bp
  • G to A, chromosome 14 at 64,123,208 bp
  • A to T, chromosome 14 at 103,145,942 bp
  • T to C, chromosome 14 at 103,208,893 bp
  • A to T, chromosome 15 at 31,509,764 bp
  • T to C, chromosome 15 at 35,937,283 bp
  • G to T, chromosome 15 at 53,101,744 bp
  • A to G, chromosome 15 at 66,782,714 bp
  • A to G, chromosome 15 at 81,682,014 bp
  • T to C, chromosome 15 at 85,816,506 bp
  • T to C, chromosome 15 at 93,397,186 bp
  • A to T, chromosome 16 at 38,498,951 bp
  • A to G, chromosome 16 at 87,382,713 bp
  • A to T, chromosome 16 at 97,743,733 bp
  • C to T, chromosome 17 at 34,857,278 bp
  • A to G, chromosome 17 at 42,317,074 bp
  • T to C, chromosome 18 at 37,974,456 bp
  • T to A, chromosome 18 at 46,990,537 bp
  • A to G, chromosome 19 at 6,112,798 bp
  • A to G, chromosome 19 at 8,708,244 bp
  • T to C, chromosome 19 at 29,646,065 bp
  • T to C, chromosome 19 at 42,044,059 bp
  • T to C, chromosome 19 at 44,534,696 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2135 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040138-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.