Strain Name:
C57BL/6J-MtgxR4618Btlr/Mmmh
Stock Number:
041884-MU
Citation ID:
RRID:MMRRC_041884-MU
Other Names:
R4618 (G1), C57BL/6J-MtgxR4618Btlr
Major Collection:

Gene Information

Fbxo36
Name: F-box protein 36
Synonyms: 0610008D19Rik, 2410002G19Rik, 1110020F21Rik, D1Ertd757e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 66153
Homologene: 11927
Rnf38
Name: ring finger protein 38
Synonyms: Oip1, 1700065B19Rik, 2610202O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 73469
Homologene: 32550
Senp6
Name: SUMO/sentrin specific peptidase 6
Synonyms: E130319N12Rik, 2810017C20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 215351
Homologene: 9196
Asap1
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain1
Synonyms: Ddef1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 13196
HGNC: HGNC:2720
Homologene: 7684
Tacc2
Name: transforming, acidic coiled-coil containing protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 57752
Homologene: 5087
Sorbs1
Name: sorbin and SH3 domain containing 1
Synonyms: c-Cbl-associated protein, CAP, Sh3d5, 9530001P15Rik, 2310065E01Rik, Ponsin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20411
VEGA: 19
Homologene: 83252
Atf7ip
Name: activating transcription factor 7 interacting protein
Synonyms: ATFa-associated Modulator, AM, 2610204M12Rik, Mcaf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54343
Homologene: 10051
Nol10
Name: nucleolar protein 10
Synonyms: LOC217431
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217431
VEGA: 12
Homologene: 5998
Opa1
Name: OPA1, mitochondrial dynamin like GTPase
Synonyms: 1200011N24Rik, lilr3, optic atrophy 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74143
HGNC: HGNC:8140
Homologene: 14618
Ccdc14
Name: coiled-coil domain containing 14
Synonyms: G630039H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239839
VEGA: 16
Homologene: 32549
Usp22
Name: ubiquitin specific peptidase 22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216825
Homologene: 52664
Serpini1
Name: serine (or cysteine) peptidase inhibitor, clade I, member 1
Synonyms: Neuroserpin, PI12, Spi17, Ns
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20713
HGNC: HGNC:8943
Homologene: 21045
Nop14
Name: NOP14 nucleolar protein
Synonyms: 2610033H07Rik, Nol14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75416
Homologene: 41773
Gins1
Name: GINS complex subunit 1 (Psf1 homolog)
Synonyms: Psf1, 2810418N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 69270
Homologene: 44516
Hsph1
Name: heat shock 105kDa/110kDa protein 1
Synonyms: hsp-E7I, HSP110, Hsp105, hsp110/105
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 15505
Homologene: 21322
Tbc1d14
Name: TBC1 domain family, member 14
Synonyms: 2810413P16Rik, D5Ertd110e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100855
Homologene: 10809
Trhr
Name: thyrotropin releasing hormone receptor
Synonyms: TRH-R1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 22045
VEGA: 15
Homologene: 20707
Grin2c
Name: glutamate receptor, ionotropic, NMDA2C (epsilon 3)
Synonyms: NMDAR2C, NR2C, GluRepsilon3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14813
HGNC: HGNC:4587
Homologene: 647
Tsg101
Name: tumor susceptibility gene 101
Synonyms: CC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22088
Homologene: 4584
Lmbr1
Name: limb region 1
Synonyms: 1110048D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56873
Homologene: 49706
Gcnt2
Name: glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
Synonyms: IGnTC, IGnTB, IGnTA, 5330430K10Rik, IGnT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14538
VEGA: 13
HGNC: HGNC:4204
Homologene: 41535
Nid2
Name: nidogen 2
Synonyms: entactin-2, entactin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18074
VEGA: 14
Homologene: 40575
Naxd
Name: NAD(P)HX dehydratase
Synonyms: 2810407E01Rik, 0710008K08Rik, Carkd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 69225
Homologene: 6333
Nbeal1
Name: neurobeachin like 1
Synonyms: ALS2CR17, A530083I02Rik, A530050O19Rik, 2310076G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269198
Homologene: 16453
Zdhhc11
Name: zinc finger, DHHC domain containing 11
Synonyms: 4933421L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 71164
VEGA: 13
Homologene: 128723
Pde4d
Name: phosphodiesterase 4D, cAMP specific
Synonyms: dunce, Dpde3, 9630011N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238871
HGNC: HGNC:8783
Bcl2a1a
Name: B cell leukemia/lymphoma 2 related protein A1a
Synonyms: A1, Bfl-1, Bcl2a1, Hbpa1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12044
HGNC: HGNC:991
Homologene: 2988
Maml2
Name: mastermind like transcriptional coactivator 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270118
Homologene: 134147
Akap3
Name: A kinase (PRKA) anchor protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11642
HGNC: HGNC:373
Homologene: 4688
Adamtsl3
Name: ADAMTS-like 3
Synonyms: punctin-2, 9230119C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269959
Homologene: 18912
Aifm3
Name: apoptosis-inducing factor, mitochondrion-associated 3
Synonyms: 2810401C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 72168
Homologene: 13773
Fcer1a
Name: Fc receptor, IgE, high affinity I, alpha polypeptide
Synonyms: Fce1a, Fcr-5, FcERI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14125
HGNC: HGNC:3609
Homologene: 1516
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 192190
Homologene: 16332
Olfr73
Name: olfactory receptor 73
Synonyms: mOR-EG, MOR174-9, GA_x6K02T2Q125-49527073-49526132
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 117004
Homologene: 133889
Btnl6
Name: butyrophilin-like 6
Synonyms: NG13, Gm6519
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 624681
Homologene: 106849
Man2c1
Name: mannosidase, alpha, class 2C, member 1
Synonyms: 1110025H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73744
HGNC: HGNC:6827
Homologene: 4887
Lonp1
Name: lon peptidase 1, mitochondrial
Synonyms: LON, 1200017E13Rik, Prss15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74142
VEGA: 17
HGNC: HGNC:9479
Homologene: 3521
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241516
Homologene: 110349
Nfatc1
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
Synonyms: NFAT2, NFATc, NF-ATc, 2210017P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 18018
VEGA: 18
HGNC: HGNC:7775
Homologene: 32336
Mtrf1l
Name: mitochondrial translational release factor 1-like
Synonyms: 9130004K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 108853
Homologene: 5905
Zfp352
Name: zinc finger protein 352
Synonyms: 2czf48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 236537
Homologene: 45160
Ptprt
Name: protein tyrosine phosphatase, receptor type, T
Synonyms: RPTPrho
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19281
HGNC: HGNC:9682
Homologene: 56924
Olfr714
Name: olfactory receptor 714
Synonyms: GA_x6K02T2PBJ9-9453401-9454354, MOR263-2, P4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259035
HGNC: HGNC:8161
Homologene: 72055
Trmt1l
Name: tRNA methyltransferase 1 like
Synonyms: Trm1-like, 1190005F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98685
Homologene: 12801
Ghrhr
Name: growth hormone releasing hormone receptor
Synonyms: Ghrfr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14602
HGNC: HGNC:4266
Homologene: 640
Vmn2r18
Name: vomeronasal 2, receptor 18
Synonyms: EG632671
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 632671
Itih1
Name: inter-alpha trypsin inhibitor, heavy chain 1
Synonyms: inter-alpha (globulin) inhibitor, H1 polypeptide, Intin1, Itih-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16424
HGNC: HGNC:6166
Homologene: 1667
Vmn2r66
Name: vomeronasal 2, receptor 66
Synonyms: F830104D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233437
Homologene: 115466
Rfx4
Name: regulatory factor X, 4 (influences HLA class II expression)
Synonyms: 4933412G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71137
HGNC: HGNC:9985
Homologene: 31119
Greb1l
Name: growth regulation by estrogen in breast cancer-like
Synonyms: mKIAA4095, AK220484
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 381157
Homologene: 73393
Olfr1100
Name: olfactory receptor 1100
Synonyms: GA_x6K02T2Q125-48465387-48464422, MOR206-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258587
Homologene: 34954
Samd9l
Name: sterile alpha motif domain containing 9-like
Synonyms: ESTM25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 209086
HGNC: HGNC:1349
Homologene: 7707
Phykpl
Name: 5-phosphohydroxy-L-lysine phospholyase
Synonyms: 2900006B13Rik, Agxt2l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72947
Homologene: 75268
Klhdc7b
Name: kelch domain containing 7B
Synonyms: EG546648
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 546648
Homologene: 34707
Rad21
Name: RAD21 cohesin complex component
Synonyms: SCC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 19357
VEGA: 15
HGNC: HGNC:9811
Homologene: 38161
Tsen54
Name: tRNA splicing endonuclease subunit 54
Synonyms: 0610034P02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76265
Homologene: 35476
Gm16519
Name: predicted gene, 16519
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 546695
VEGA: 17
Adprhl1
Name: ADP-ribosylhydrolase like 1
Synonyms: Arh2, D330008N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234072
Homologene: 16311
C9
Name: complement component 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12279
HGNC: HGNC:1358
Homologene: 74406
Noxa1
Name: NADPH oxidase activator 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241275
Homologene: 18156
Endou
Name: endonuclease, polyU-specific
Synonyms: Tcl-30, Pp11r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 19011
VEGA: 15
Homologene: 48394
Vmn2r45
Name: vomeronasal 2, receptor 45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100042810
Homologene: 113703
Vsig1
Name: V-set and immunoglobulin domain containing 1
Synonyms: 1700062D20Rik, 4930405J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 78789
Homologene: 12703
4930432M17Rik
Name: RIKEN cDNA 4930432M17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 619318
Tbrg4
Name: transforming growth factor beta regulated gene 4
Synonyms: TB-12, Cpr2, 2310042P22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21379
Homologene: 31259
Vmn1r209
Name: vomeronasal 1 receptor 209
Synonyms: Gm11315
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 432736
Homologene: 110880
Mrps15
Name: mitochondrial ribosomal protein S15
Synonyms: 1500003E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66407
Homologene: 32636
Man2b2
Name: mannosidase 2, alpha B2
Synonyms: 135 kDa alpha-D-mannosidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17160
Homologene: 7411
Atxn7l2
Name: ataxin 7-like 2
Synonyms: 2610528J18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72522
Homologene: 17728
Olfr1342
Name: olfactory receptor 1342
Synonyms: GA_x6K02T2QD9B-18856980-18857927, MOR258-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 258708
Homologene: 17357
4930447C04Rik
Name: RIKEN cDNA 4930447C04 gene
Synonyms: Six6as, Six6os1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 75801
Homologene: 49922
Pkd2l1
Name: polycystic kidney disease 2-like 1
Synonyms: polycystin-L, Pkdl, PCL, TRPP3, PKD2L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 329064
HGNC: HGNC:9011
Homologene: 22946
Tpp1
Name: tripeptidyl peptidase I
Synonyms: Cln2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12751
HGNC: HGNC:2073
Homologene: 335
Tox2
Name: TOX high mobility group box family member 2
Synonyms: RxHMG1, LOC269389
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269389
Homologene: 13155
Sirt6
Name: sirtuin 6
Synonyms: 2810449N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 50721
Homologene: 6924
Heatr4
Name: HEAT repeat containing 4
Synonyms: Gm17673
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 101055670
Homologene: 45728
Cd5l
Name: CD5 antigen-like
Synonyms: AAC-11, AIM/Spalpha, Sp-alpha, Pdp 1/6, Api6, AIM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11801
HGNC: HGNC:1690
Homologene: 55936
Gpr20
Name: G protein-coupled receptor 20
Synonyms: A430106B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239530
HGNC: HGNC:4475
Homologene: 3870
Cstdc3
Name: cystatin domain containing 3
Synonyms: Gm4758
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 209324
VEGA: 16
HGNC: HGNC:2481
Homologene: 86375
Mettl11b
Name: methyltransferase like 11B
Synonyms: LOC240879
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240879
Homologene: 28168
Ighv1-82
Name: immunoglobulin heavy variable 1-82
Synonyms: Gm16747
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 100775175
Hes2
Name: hes family bHLH transcription factor 2
Synonyms: HES-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15206
Homologene: 22455
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 60,228,731 bp
  • T to C, chromosome 1 at 84,900,028 bp
  • C to T, chromosome 1 at 151,454,048 bp
  • A to T, chromosome 1 at 163,725,028 bp
  • T to C, chromosome 1 at 173,222,641 bp
  • C to T, chromosome 2 at 25,091,749 bp
  • A to G, chromosome 2 at 82,987,759 bp
  • A to G, chromosome 2 at 86,978,274 bp
  • A to G, chromosome 2 at 88,034,554 bp
  • T to A, chromosome 2 at 150,917,861 bp
  • T to C, chromosome 2 at 161,553,845 bp
  • T to C, chromosome 2 at 163,320,647 bp
  • A to G, chromosome 3 at 75,616,576 bp
  • A to G, chromosome 3 at 87,368,619 bp
  • T to A, chromosome 3 at 108,207,519 bp
  • A to T, chromosome 3 at 121,679,446 bp
  • A to G, chromosome 4 at 44,142,450 bp
  • A to G, chromosome 4 at 90,225,081 bp
  • A to T, chromosome 4 at 118,689,470 bp
  • G to A, chromosome 4 at 126,047,044 bp
  • A to C, chromosome 4 at 152,160,388 bp
  • G to T, chromosome 5 at 29,346,865 bp
  • G to T, chromosome 5 at 34,639,218 bp
  • A to C, chromosome 5 at 36,530,381 bp
  • G to T, chromosome 5 at 36,817,639 bp
  • A to G, chromosome 5 at 149,618,843 bp
  • A to T, chromosome 5 at 151,584,959 bp
  • C to A, chromosome 6 at 3,376,347 bp
  • T to C, chromosome 6 at 55,381,754 bp
  • G to T, chromosome 6 at 126,866,443 bp
  • G to T, chromosome 6 at 136,565,106 bp
  • A to T, chromosome 7 at 8,483,437 bp
  • A to G, chromosome 7 at 46,892,509 bp
  • T to A, chromosome 7 at 82,606,520 bp
  • T to C, chromosome 7 at 84,995,088 bp
  • A to T, chromosome 7 at 105,751,706 bp
  • G to A, chromosome 7 at 107,074,554 bp
  • A to T, chromosome 7 at 130,626,216 bp
  • A to T, chromosome 8 at 11,509,489 bp
  • A to G, chromosome 8 at 13,242,250 bp
  • T to C, chromosome 9 at 13,620,075 bp
  • T to C, chromosome 9 at 57,142,155 bp
  • T to C, chromosome 9 at 80,122,018 bp
  • A to C, chromosome 9 at 88,957,304 bp
  • C to A, chromosome 10 at 5,817,586 bp
  • A to G, chromosome 10 at 81,626,574 bp
  • G to T, chromosome 10 at 84,880,896 bp
  • G to A, chromosome 11 at 6,620,185 bp
  • G to A, chromosome 11 at 51,592,229 bp
  • A to G, chromosome 11 at 61,161,443 bp
  • T to A, chromosome 11 at 115,252,747 bp
  • T to A, chromosome 11 at 115,815,421 bp
  • T to C, chromosome 12 at 17,348,561 bp
  • T to C, chromosome 12 at 72,902,485 bp
  • T to G, chromosome 12 at 83,978,067 bp
  • T to C, chromosome 12 at 115,952,660 bp
  • A to G, chromosome 13 at 22,806,449 bp
  • T to A, chromosome 13 at 40,958,194 bp
  • T to A, chromosome 13 at 73,979,230 bp
  • A to T, chromosome 13 at 109,933,877 bp
  • T to A, chromosome 14 at 19,808,010 bp
  • A to T, chromosome 14 at 30,929,831 bp
  • A to G, chromosome 15 at 6,491,463 bp
  • A to G, chromosome 15 at 44,197,641 bp
  • T to A, chromosome 15 at 44,539,682 bp
  • A to T, chromosome 15 at 51,970,024 bp
  • A to T, chromosome 15 at 64,152,895 bp
  • T to C, chromosome 15 at 73,695,736 bp
  • A to G, chromosome 15 at 89,387,269 bp
  • C to T, chromosome 15 at 97,713,882 bp
  • C to A, chromosome 16 at 17,506,275 bp
  • T to C, chromosome 16 at 29,587,039 bp
  • T to A, chromosome 16 at 34,706,495 bp
  • T to A, chromosome 16 at 36,312,590 bp
  • G to A, chromosome 17 at 34,514,146 bp
  • A to C, chromosome 17 at 56,622,511 bp
  • T to G, chromosome 17 at 70,929,242 bp
  • A to G, chromosome 18 at 10,498,965 bp
  • T to C, chromosome 18 at 80,697,832 bp
  • T to C, chromosome 19 at 40,373,518 bp
  • C to A, chromosome 19 at 44,154,134 bp
  • G to T, chromosome X at 140,926,386 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4618 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041884-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.