Strain Name:
C57BL/6J-MtgxR5799Btlr
Stock Number:
043388-MU
Citation ID:
RRID:MMRRC_043388-MU
Other Names:
R5799 (G1)
Major Collection:

Gene Information

Stam2
Name: signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
Synonyms: Hbp, 1200004O12Rik, 5730456G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56324
Homologene: 68490
Atg14
Name: autophagy related 14
Synonyms: D14Ertd114e, D14Ertd436e, Barkor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100504663
VEGA: 14
Homologene: 45423
Senp7
Name: SUMO1/sentrin specific peptidase 7
Synonyms: 6030449K19Rik, 2810413I22Rik, 2410152H17Rik, 2900036C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 66315
Homologene: 10778
Trrap
Name: transformation/transcription domain-associated protein
Synonyms: transactivation/transformation-domain associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100683
Homologene: 39246
Slc38a2
Name: solute carrier family 38, member 2
Synonyms: 5033402L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67760
VEGA: 15
Homologene: 23132
Rttn
Name: rotatin
Synonyms: 4921538A15Rik, C530033I08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 246102
VEGA: 18
Homologene: 65275
Exd1
Name: exonuclease 3'-5' domain containing 1
Synonyms: 4932702D22Rik, Exdl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241624
Homologene: 17627
Calcr
Name: calcitonin receptor
Synonyms: Clr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12311
HGNC: HGNC:1440
Homologene: 1320
Dnmt3l
Name: DNA (cytosine-5-)-methyltransferase 3-like
Synonyms: ecat7, D6Ertd14e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 54427
HGNC: HGNC:2980
Homologene: 8362
Jak3
Name: Janus kinase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16453
HGNC: HGNC:6193
Homologene: 181
Ext2
Name: exostosin glycosyltransferase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14043
HGNC: HGNC:3513
Homologene: 345
Ddhd2
Name: DDHD domain containing 2
Synonyms: 2010305K11Rik, SAMWD1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72108
Homologene: 66646
Eea1
Name: early endosome antigen 1
Synonyms: B230358H09Rik, A430109M19Rik, ZFYVE2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216238
VEGA: 10
HGNC: HGNC:3185
Homologene: 37822
Taf6l
Name: TATA-box binding protein associated factor 6 like
Synonyms: 2810417N14Rik, C530024J06Rik, PAF65A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225895
Homologene: 4728
Slc35e2
Name: solute carrier family 35, member E2
Synonyms: A530082C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 320541
Homologene: 84987
Col13a1
Name: collagen, type XIII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12817
HGNC: HGNC:2190
Homologene: 22421
Lig1
Name: ligase I, DNA, ATP-dependent
Synonyms: LigI, mLigI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16881
HGNC: HGNC:6598
Homologene: 197
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Ahnak2
Name: AHNAK nucleoprotein 2
Synonyms: LOC382643
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 100041194
Homologene: 131081
Cass4
Name: Cas scaffolding protein family member 4
Synonyms: F730031O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320664
Homologene: 75128
Chmp6
Name: charged multivesicular body protein 6
Synonyms: chromatin modifying protein 6, 2400004G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 208092
Homologene: 11607
Tex10
Name: testis expressed gene 10
Synonyms: 2610206N19Rik, 2810462N03Rik, clone 18330
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269536
Homologene: 32361
Lhpp
Name: phospholysine phosphohistidine inorganic pyrophosphate phosphatase
Synonyms: 2310007H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76429
Homologene: 41469
Nrap
Name: nebulin-related anchoring protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18175
HGNC: HGNC:7988
Homologene: 4499
Narf
Name: nuclear prelamin A recognition factor
Synonyms: 4430402O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67608
Homologene: 57048
Lipo3
Name: lipase, member O3
Synonyms: Lipo1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 381236
Homologene: 103863
Tgfbr3
Name: transforming growth factor, beta receptor III
Synonyms: betaglycan, TBRIII, 1110036H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 21814
Homologene: 2436
Asap2
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
Synonyms: Ddef2, 6530401G17Rik, LOC385250
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 211914
HGNC: HGNC:2721
Homologene: 2888
Fam186a
Name: family with sequence similarity 186, member A
Synonyms: LOC380973, 1700030F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72277
Efcc1
Name: EF hand and coiled-coil domain containing 1
Synonyms: Ccdc48, AB041550
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 58229
Homologene: 130011
Pdzd7
Name: PDZ domain containing 7
Synonyms: Pdzk7, EG435601
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 100503041
Homologene: 129509
Nubp2
Name: nucleotide binding protein 2
Synonyms: D17Wsu11e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 26426
VEGA: 17
HGNC: HGNC:8042
Homologene: 8057
Gbp2
Name: guanylate binding protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14469
HGNC: HGNC:4183
Homologene: 10289
Ncf4
Name: neutrophil cytosolic factor 4
Synonyms: p40phox
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17972
HGNC: HGNC:7662
Homologene: 525
Alcam
Name: activated leukocyte cell adhesion molecule
Synonyms: CD166, MuSC, BEN, SC1, DM-GRASP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 11658
HGNC: HGNC:400
Homologene: 1229
Accsl
Name: 1-aminocyclopropane-1-carboxylate synthase (non-functional)-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381411
Homologene: 86007
4933416C03Rik
Name: RIKEN cDNA 4933416C03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
AA986860
Name: expressed sequence AA986860
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 212439
Homologene: 49741
Cstdc4
Name: cystatin domain containing 4
Synonyms: Gm5483
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 433016
VEGA: 16
HGNC: HGNC:2481
Homologene: 3819
Sp110
Name: Sp110 nuclear body protein
Synonyms: 5830484A20Rik, 5031415C07Rik, 52kDa, Ipr1, Ifi75
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 109032
HGNC: HGNC:5401
Homologene: 82192
Olfr972
Name: olfactory receptor 972
Synonyms: MOR171-17, GA_x6K02T2PVTD-33572803-33573747
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258603
VEGA: 9
Homologene: 121532
C230029F24Rik
Name: RIKEN cDNA C230029F24 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 442837
Lrrc8b
Name: leucine rich repeat containing 8 family, member B
Synonyms: 2210408K08Rik, R75581
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 433926
Homologene: 9103
Olfr818
Name: olfactory receptor 818
Synonyms: MOR110-2, GA_x6K02T2PULF-11624146-11623190
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258773
Homologene: 74100
Tbx20
Name: T-box 20
Synonyms: 9430010M06Rik, Tbx12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 57246
VEGA: 9
Homologene: 32476
Slc25a3
Name: solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
Synonyms: 5730556H19Rik, Phc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18674
Homologene: 37649
Olfr723
Name: olfactory receptor 723
Synonyms: MOR247-4, MOR247-3P, GA_x6K02T2PMLR-5600424-5599495
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 259147
Homologene: 71986
H2-Q5
Name: histocompatibility 2, Q region locus 5
Synonyms: H-2Q5, Qa5, Qa-5, Qat-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15016
Taf1a
Name: TATA-box binding protein associated factor, RNA polymerase I, A
Synonyms: mTAFI48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21339
Homologene: 4155
Tnfsf10
Name: tumor necrosis factor (ligand) superfamily, member 10
Synonyms: A330042I21Rik, APO-2L, Trail
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 22035
Homologene: 2824
Defa40
Name: defensin, alpha, 40
Synonyms: Gm15292, ENSMUSG00000074441
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 100041787
Homologene: 113382
Gramd2
Name: GRAM domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 546134
Homologene: 52791
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 49,338,148 bp
  • A to C, chromosome 1 at 85,577,329 bp
  • C to T, chromosome 1 at 130,741,171 bp
  • A to G, chromosome 1 at 183,395,934 bp
  • A to T, chromosome 2 at 52,720,910 bp
  • G to T, chromosome 2 at 93,811,972 bp
  • T to C, chromosome 2 at 93,864,403 bp
  • A to G, chromosome 2 at 112,686,580 bp
  • A to G, chromosome 2 at 119,538,781 bp
  • G to A, chromosome 2 at 172,416,187 bp
  • G to T, chromosome 3 at 27,335,593 bp
  • A to T, chromosome 3 at 142,632,082 bp
  • A to G, chromosome 4 at 48,433,295 bp
  • C to T, chromosome 4 at 155,610,026 bp
  • C to T, chromosome 5 at 105,481,342 bp
  • T to C, chromosome 5 at 107,109,608 bp
  • A to G, chromosome 5 at 144,830,945 bp
  • A to T, chromosome 6 at 3,707,592 bp
  • A to G, chromosome 6 at 87,731,182 bp
  • T to A, chromosome 7 at 13,296,258 bp
  • G to A, chromosome 7 at 132,705,635 bp
  • T to A, chromosome 8 at 21,250,343 bp
  • T to A, chromosome 8 at 25,748,602 bp
  • C to T, chromosome 8 at 71,678,700 bp
  • G to A, chromosome 9 at 24,725,520 bp
  • T to C, chromosome 9 at 39,874,096 bp
  • G to A, chromosome 9 at 59,708,016 bp
  • A to G, chromosome 10 at 61,849,140 bp
  • A to G, chromosome 10 at 78,052,026 bp
  • A to C, chromosome 10 at 91,122,041 bp
  • T to A, chromosome 10 at 96,002,948 bp
  • T to C, chromosome 10 at 116,112,769 bp
  • A to T, chromosome 10 at 129,945,911 bp
  • T to C, chromosome 11 at 119,916,691 bp
  • T to C, chromosome 11 at 121,244,654 bp
  • T to C, chromosome 12 at 21,168,246 bp
  • T to C, chromosome 12 at 112,778,930 bp
  • A to T, chromosome 14 at 47,547,295 bp
  • A to T, chromosome 14 at 49,929,040 bp
  • A to G, chromosome 15 at 78,250,977 bp
  • A to T, chromosome 15 at 96,695,089 bp
  • G to A, chromosome 15 at 99,966,824 bp
  • T to A, chromosome 16 at 36,184,261 bp
  • T to C, chromosome 16 at 52,309,849 bp
  • G to A, chromosome 16 at 56,139,105 bp
  • A to G, chromosome 17 at 24,885,798 bp
  • T to C, chromosome 17 at 35,394,139 bp
  • T to C, chromosome 18 at 89,037,946 bp
  • A to T, chromosome 19 at 8,782,631 bp
  • T to C, chromosome 19 at 33,777,693 bp
  • G to A, chromosome 19 at 45,036,989 bp
  • A to T, chromosome 19 at 56,342,169 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5799 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043388-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.