Strain Name:
C57BL/6J-MtgxR5156Btlr/Mmmh
Stock Number:
042738-MU
Citation ID:
RRID:MMRRC_042738-MU
Other Names:
R5156 (G1), C57BL/6J-MtgxR5156Btlr
Major Collection:

Strain Information

Ppp1r37
Name: protein phosphatase 1, regulatory subunit 37
Synonyms: Lrrc68
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232947
Homologene: 17851
Ctage5
Name: CTAGE family, member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Asf1b
Name: anti-silencing function 1B histone chaperone
Synonyms: 1700003K02Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66929
Homologene: 56797
Arap2
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonyms: Centd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 212285
Homologene: 9064
Plekha5
Name: pleckstrin homology domain containing, family A member 5
Synonyms: PEPP2, 2810431N21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 109135
Homologene: 10377
Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
Synonyms: MAP1C, dynein heavy chain, retrograde transport, Dnec1, Loa, 9930018I23Rik, Dnchc1, Swl
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13424
HGNC: HGNC:2961
Homologene: 1053
Epha8
Name: Eph receptor A8
Synonyms: EphA8, Hek3, Eek
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13842
HGNC: HGNC:3391
Homologene: 22436
Dmbt1
Name: deleted in malignant brain tumors 1
Synonyms: CRP-[b], CRP-[a], ebnerin, hensin, vomeroglandin, Crpd, MUCLIN, gp300
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12945
HGNC: HGNC:2926
Homologene: 68990
Fzd10
Name: frizzled class receptor 10
Synonyms: Fz-10
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 93897
HGNC: HGNC:4039
Homologene: 21411
Ikzf1
Name: IKAROS family zinc finger 1
Synonyms: LyF-1, Ikaros, 5832432G11Rik, Zfpn1a1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22778
Homologene: 55948
Slitrk3
Name: SLIT and NTRK-like family, member 3
Synonyms: ST3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 386750
Homologene: 8955
Efemp2
Name: epidermal growth factor-containing fibulin-like extracellular matrix protein 2
Synonyms: fibulin 4, MBP1, fibulin-4, 0610011K11Rik, Fbln4
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 58859
HGNC: HGNC:3219
Homologene: 32339
Sec13
Name: SEC13 homolog, nuclear pore and COPII coat complex component
Synonyms: 1110003H02Rik, Sec13r, Sec13l1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 110379
Homologene: 6479
Foxk1
Name: forkhead box K1
Synonyms: Mnf, A630048H08Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 17425
Homologene: 82414
Edrf1
Name: erythroid differentiation regulatory factor 1
Synonyms: 2700050L05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 214764
Homologene: 27985
Tnfsfm13
Name: tumor necrosis factor (ligand) superfamily, membrane-bound member 13
Synonyms: TWE-PRIL, Tnfsf12-Tnfsf13, Tnfsf12tnfsf13, BC096441
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 619441
Homologene: 123930
Muc19
Name: mucin 19
Synonyms: apomucin, sld
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239611
Apeh
Name: acylpeptide hydrolase
Synonyms: N-acylaminoacyl peptide hydrolase
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235606
HGNC: HGNC:586
Homologene: 1240
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: hy-3, hy3, 1700034M11Rik, 4930545D19Rik, hyrh
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244653
Homologene: 52118
Dmpk
Name: dystrophia myotonica-protein kinase
Synonyms: DM, Dm15
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13400
HGNC: HGNC:2933
Homologene: 3247
Cfap53
Name: cilia and flagella associated protein 53
Synonyms: 4933415I03Rik, Ccdc11
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 74453
Homologene: 27056
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: VLGR1, Mass1, Mgr1, Gpr98
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110789
Homologene: 19815
Neu4
Name: sialidase 4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241159
Homologene: 15433
Csf1
Name: colony stimulating factor 1 (macrophage)
Synonyms: CSF-1, M-CSF, colony-stimulating factor-1, Csfm, BAP025
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12977
HGNC: HGNC:2432
Homologene: 7282
Clca3a2
Name: chloride channel accessory 3A2
Synonyms: Clca2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80797
HGNC: HGNC:2017
Homologene: 77224
Vmn2r10
Name: vomeronasal 2, receptor 10
Synonyms: VR16, V2r16
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22307
Homologene: 129606
Trank1
Name: tetratricopeptide repeat and ankyrin repeat containing 1
Synonyms: A230061D21Rik, LOC235639, C030048J01Rik, Lba1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320429
Homologene: 45845
Ttc23l
Name: tetratricopeptide repeat domain 23-like
Synonyms: 4930401A09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75777
Homologene: 44907
Vmn2r75
Name: vomeronasal 2, receptor 75
Synonyms: EG546981
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 546981
Homologene: 115466
Vwa8
Name: von Willebrand factor A domain containing 8
Synonyms: 4932416F07Rik, 1300010F03Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219189
VEGA: 14
Homologene: 44881
Krt20
Name: keratin 20
Synonyms: 9030623C06Rik, CK20, cytokeratin 20
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66809
Homologene: 56837
Rfx4
Name: regulatory factor X, 4 (influences HLA class II expression)
Synonyms: 4933412G19Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71137
HGNC: HGNC:9985
Homologene: 31119
Trim10
Name: tripartite motif-containing 10
Synonyms: Herf1, Rnf9
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19824
Homologene: 4932
Speg
Name: SPEG complex locus
Synonyms: BPEG, SPEGbeta, SPEGalpha, D1Bwg1450e, SPEG, Apeg1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11790
Homologene: 55619
Sp100
Name: nuclear antigen Sp100
Synonyms: A430075G10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20684
Homologene: 86761
Ppef2
Name: protein phosphatase, EF hand calcium-binding domain 2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19023
HGNC: HGNC:9244
Homologene: 55959
Nrap
Name: nebulin-related anchoring protein
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18175
HGNC: HGNC:7988
Homologene: 4499
Sanbr
Name: SANT and BTB domain regulator of CSR
Synonyms: 0610010F05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71675
Homologene: 19038
Or5b118
Name: olfactory receptor family 5 subfamily B member 118
Synonyms: GA_x6K02T2RE5P-3803583-3804527, MOR202-42, MOR202-26P, Olfr1474
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258123
Homologene: 79417
Or8k41
Name: olfactory receptor family 8 subfamily K member 41
Synonyms: GA_x6K02T0101M-139-669, MOR189-3, Olfr228, GA_x6K02T2Q125-47962802-47962551, Olfr1071
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258400
Homologene: 17233
Cd46
Name: CD46 antigen, complement regulatory protein
Synonyms: CD46, Mcp
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17221
HGNC: HGNC:6953
Homologene: 7832
4921513D11Rik
Name: RIKEN cDNA 4921513D11 gene
Type: Gene
Species: Mouse
Chromosome: 17
Lrrc71
Name: leucine rich repeat containing 71
Synonyms: 4933430H15Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74485
Homologene: 83646
Spata2
Name: spermatogenesis associated 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 263876
Homologene: 4407
Nt5m
Name: 5',3'-nucleotidase, mitochondrial
Synonyms: 2010013E09Rik, dNT-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103850
Homologene: 10622
Or5w15
Name: olfactory receptor family 5 subfamily W member 15
Synonyms: GA_x6K02T2Q125-49242149-49241214, MOR177-8, Olfr1138
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258632
Homologene: 74082
Cdca7
Name: cell division cycle associated 7
Synonyms: JPO1, 2310021G01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66953
Homologene: 49970
Dnajb12
Name: DnaJ heat shock protein family (Hsp40) member B12
Synonyms: mDj10
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 56709
Homologene: 9749
Serhl
Name: serine hydrolase-like
Synonyms: 1110019M09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 68607
Homologene: 65196
Slco4a1
Name: solute carrier organic anion transporter family, member 4a1
Synonyms: OATP-E, Slc21a12
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 108115
Homologene: 9482
Gm6818
Name: predicted gene 6818
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 627975
Homologene: 80005
AC107766.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Gm13991
Name: predicted gene 13991
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 433464
RP23-3C4.2
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 34,723,274 bp
  • T to C, chromosome 1 at 75,428,087 bp
  • T to A, chromosome 1 at 85,673,683 bp
  • T to C, chromosome 1 at 94,024,455 bp
  • T to A, chromosome 1 at 195,085,385 bp
  • A to T, chromosome 2 at 72,479,026 bp
  • A to T, chromosome 2 at 86,483,018 bp
  • G to A, chromosome 2 at 87,737,775 bp
  • T to C, chromosome 2 at 116,528,184 bp
  • G to T, chromosome 2 at 167,483,574 bp
  • T to C, chromosome 2 at 180,472,779 bp
  • T to C, chromosome 3 at 73,049,259 bp
  • T to A, chromosome 3 at 87,745,787 bp
  • T to G, chromosome 3 at 98,124,310 bp
  • T to A, chromosome 3 at 107,748,936 bp
  • T to A, chromosome 3 at 144,805,838 bp
  • C to T, chromosome 4 at 136,938,726 bp
  • A to T, chromosome 5 at 62,669,181 bp
  • A to G, chromosome 5 at 92,244,602 bp
  • G to A, chromosome 5 at 93,638,705 bp
  • A to G, chromosome 5 at 108,995,600 bp
  • C to A, chromosome 5 at 128,601,302 bp
  • A to G, chromosome 5 at 142,448,833 bp
  • G to A, chromosome 6 at 113,730,876 bp
  • C to T, chromosome 6 at 140,426,528 bp
  • A to G, chromosome 7 at 19,084,125 bp
  • T to C, chromosome 7 at 19,561,975 bp
  • A to T, chromosome 7 at 38,402,047 bp
  • T to A, chromosome 7 at 86,164,228 bp
  • T to C, chromosome 7 at 131,097,670 bp
  • C to T, chromosome 7 at 133,660,179 bp
  • T to C, chromosome 8 at 83,955,911 bp
  • T to A, chromosome 8 at 110,609,701 bp
  • C to T, chromosome 9 at 108,094,287 bp
  • A to G, chromosome 9 at 111,390,694 bp
  • T to A, chromosome 10 at 59,892,960 bp
  • T to C, chromosome 10 at 84,868,354 bp
  • T to A, chromosome 11 at 11,769,448 bp
  • A to G, chromosome 11 at 23,593,424 bp
  • A to T, chromosome 11 at 59,874,661 bp
  • A to G, chromosome 11 at 69,687,329 bp
  • G to T, chromosome 11 at 99,430,053 bp
  • A to G, chromosome 12 at 59,172,537 bp
  • T to A, chromosome 12 at 110,628,830 bp
  • T to A, chromosome 13 at 81,520,642 bp
  • T to A, chromosome 14 at 78,984,226 bp
  • G to T, chromosome 15 at 10,551,550 bp
  • G to A, chromosome 15 at 83,102,694 bp
  • T to A, chromosome 15 at 91,900,420 bp
  • T to A, chromosome 17 at 36,877,056 bp
  • G to T, chromosome 17 at 79,628,209 bp
  • T to A, chromosome 18 at 74,359,767 bp
  • T to A, chromosome 19 at 5,477,678 bp
  • G to T, chromosome 19 at 13,471,673 bp
  • A to G, chromosome 19 at 56,371,845 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5156 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042738-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.