Strain Name:
C57BL/6J-MtgxR7152Btlr/Mmmh
Stock Number:
045254-MU
Citation ID:
RRID:MMRRC_045254-MU
Other Names:
R7152 (G1)
Major Collection:

Strain Information

Epha7
Name: Eph receptor A7
Synonyms: MDK1, Hek11, Mdk1, Cek11, Ebk, Ehk3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13841
HGNC: HGNC:3390
Homologene: 20935
Cdkn2c
Name: cyclin dependent kinase inhibitor 2C
Synonyms: p18INK4c, INK4c, p18
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12580
HGNC: HGNC:1789
Homologene: 966
Ggta1
Name: glycoprotein galactosyltransferase alpha 1, 3
Synonyms: Ggta, GALT, glycoprotein alpha galactosyl transferase 1, Ggta-1, Gal, alpha Gal, alpha3GalT
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14594
HGNC: HGNC:4253
Homologene: 7730
Cdyl2
Name: chromodomain protein, Y chromosome-like 2
Synonyms: 4930453I21Rik, 1700029M19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 75796
Homologene: 41779
Ltn1
Name: listerin E3 ubiquitin protein ligase 1
Synonyms: 4930528H02Rik, Listerin, Zfp294, Rnf160
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78913
VEGA: 16
Homologene: 32272
Zfhx3
Name: zinc finger homeobox 3
Synonyms: A230102L03Rik, Atbf1, Sci, WBP9
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11906
HGNC: HGNC:777
Homologene: 21366
Pcnt
Name: pericentrin (kendrin)
Synonyms: m275Asp, Pcnt2, m239Asp
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18541
VEGA: 10
Supt5
Name: suppressor of Ty 5, DSIF elongation factor subunit
Synonyms: Spt5, Supt5h
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20924
Homologene: 2384
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: Pcp-1, Pcp1, IP3R1, InsP3R type I, P400, Ip3r, opt, wblo, Itpr-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Pgm3
Name: phosphoglucomutase 3
Synonyms: 2810473H05Rik, Pgm-3, GlcNAc-P mutase
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 109785
HGNC: HGNC:8907
Homologene: 9205
Cntnap1
Name: contactin associated protein-like 1
Synonyms: Nrxn4, p190, NCP1, shm, paranodin, Caspr
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 53321
HGNC: HGNC:8011
Homologene: 2693
Casz1
Name: castor zinc finger 1
Synonyms: D4Ertd432e, 2410019P08Rik, Cst, castor
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69743
Homologene: 9824
Ddx17
Name: DEAD box helicase 17
Synonyms: 2610007K22Rik, A430025E01Rik, p72, DEAD (Asp-Glu-Ala-Asp) box polypeptide 17, LOC381024
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67040
VEGA: 15
HGNC: HGNC:2740
Homologene: 101101
Zfyve26
Name: zinc finger, FYVE domain containing 26
Synonyms: 9330197E15Rik, A630028O16Rik, LOC380767
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 211978
VEGA: 12
Homologene: 9102
Eps8l2
Name: EPS8-like 2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 98845
Homologene: 69358
Zbtb7b
Name: zinc finger and BTB domain containing 7B
Synonyms: Zfp67, c-Krox, Thpok
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 22724
Homologene: 7605
Foxd3
Name: forkhead box D3
Synonyms: Genesis, CWH3, Hfh2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 15221
HGNC: HGNC:3804
Homologene: 49239
Stxbp2
Name: syntaxin binding protein 2
Synonyms: Munc-18-2, Munc18b, muSec1, C79054, Sxtp2, Munc-18b
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20911
Homologene: 55530
Ndst3
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
Synonyms: 4930511P15Rik, 4921531K01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 83398
HGNC: HGNC:7682
Homologene: 3513
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Cspg4b
Name: chondroitin sulfate proteoglycan 4B
Synonyms: BC067074
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 408066
Cited2
Name: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
Synonyms: p35srj, Msg2, Mrg1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17684
VEGA: 10
HGNC: HGNC:1987
Homologene: 4433
Slc9a5
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 5
Synonyms: LOC277973
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 277973
Homologene: 31247
Or51k1
Name: olfactory receptor family 51 subfamily K member 1
Synonyms: Olfr639, MOR12-1, GA_x6K02T2PBJ9-6747143-6746193
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259088
Homologene: 17497
Vmn1r37
Name: vomeronasal 1 receptor 37
Synonyms: V1rc10
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171183
Homologene: 110800
Neb
Name: nebulin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Uspl1
Name: ubiquitin specific peptidase like 1
Synonyms: E430026A01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231915
Homologene: 4235
Esyt1
Name: extended synaptotagmin-like protein 1
Synonyms: vp115, Mbc2, Fam62a
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 23943
VEGA: 10
Homologene: 40794
Fbxl13
Name: F-box and leucine-rich repeat protein 13
Synonyms: 4921539K22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320118
Homologene: 27057
Or8k33
Name: olfactory receptor family 8 subfamily K member 33
Synonyms: MOR192-1, Olfr1080, GA_x6K02T2Q125-48039418-48038477
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258404
Homologene: 104285
Igkv8-18
Name: immunoglobulin kappa variable 8-18
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 667859
HGNC: HGNC:5834
Vmn1r124
Name: vomeronasal 1 receptor 124
Synonyms: Gm9500
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 670764
Homologene: 104166
Pomgnt2
Name: protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2
Synonyms: Gtdc2, C85492
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 215494
VEGA: 9
Homologene: 32795
Pam
Name: peptidylglycine alpha-amidating monooxygenase
Synonyms: PHM
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18484
HGNC: HGNC:8596
Homologene: 37369
Cntln
Name: centlein, centrosomal protein
Synonyms: B430108F07Rik, D530005L17Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 338349
Homologene: 9805
Cgrrf1
Name: cell growth regulator with ring finger domain 1
Synonyms: 1810009H17Rik, 1110038G02Rik, CGR19
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 68755
Homologene: 4789
Tdpoz3
Name: TD and POZ domain containing 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 399674
Homologene: 128308
Tead2
Name: TEA domain family member 2
Synonyms: TEAD-2, Etdf, TEF-4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21677
Homologene: 19662
Clip2
Name: CAP-GLY domain containing linker protein 2
Synonyms: CLIP-115, WSCR4, Cyln2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269713
HGNC: HGNC:2586
Homologene: 20718
Vnn3
Name: vanin 3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 26464
Homologene: 48295
Ctnna2
Name: catenin alpha 2
Synonyms: chp, catenin (cadherin associated protein), alpha 2, alpha N-catenin, Catna, Catna2, alpha(N)-catenin
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12386
HGNC: HGNC:2510
Homologene: 68394
Sirpb1b
Name: signal-regulatory protein beta 1B
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 668101
Homologene: 82993
Btnl10
Name: butyrophilin-like 10
Synonyms: Butr1, BUTR-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192194
Homologene: 138184
Klhl36
Name: kelch-like 36
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234796
Homologene: 32598
Slc2a12
Name: solute carrier family 2 (facilitated glucose transporter), member 12
Synonyms: GLUT-12, Glut12
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 353169
Homologene: 59263
Tssc4
Name: tumor-suppressing subchromosomal transferable fragment 4
Synonyms: ESTM671070
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56844
Homologene: 4169
Marchf3
Name: membrane associated ring-CH-type finger 3
Synonyms: March3, A530081L18Rik, 6330411I15Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 320253
Homologene: 35310
Zfp324
Name: zinc finger protein 324
Synonyms: ZF5128, D430030K24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243834
Homologene: 8648
Cers1
Name: ceramide synthase 1
Synonyms: Lass1, to, Uog-1, CerS1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 93898
Homologene: 128762
Nphp1
Name: nephronophthisis 1 (juvenile) homolog (human)
Synonyms: nephrocystin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 53885
HGNC: HGNC:7905
Homologene: 229
Sult2a6
Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6
Synonyms: Gm6957
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 629219
Homologene: 37741
Sds
Name: serine dehydratase
Synonyms: SDH
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231691
Homologene: 38235
Myl10
Name: myosin, light chain 10, regulatory
Synonyms: PLRLC-C, 1700027I08Rik, Mylc2pl, PLRLC, PLRLC-A, PLRLC-B
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 59310
Homologene: 69341
Pcdhgb1
Name: protocadherin gamma subfamily B, 1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93699
HGNC: HGNC:8708
Homologene: 81867
H3c13
Name: H3 clustered histone 13
Synonyms: Hist2h3b, H3-616
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 319154
Homologene: 136775
Ighv5-15
Name: immunoglobulin heavy variable 5-15
Synonyms: Gm16888
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 780792
HGNC: HGNC:5620
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 97,885,740 bp
  • T to A, chromosome 2 at 35,402,699 bp
  • T to C, chromosome 2 at 52,263,545 bp
  • C to T, chromosome 2 at 76,853,161 bp
  • C to T, chromosome 2 at 86,553,329 bp
  • A to G, chromosome 2 at 127,753,979 bp
  • G to T, chromosome 3 at 15,542,170 bp
  • C to T, chromosome 3 at 89,380,902 bp
  • T to C, chromosome 3 at 93,826,465 bp
  • A to G, chromosome 3 at 96,268,938 bp
  • T to A, chromosome 3 at 123,552,656 bp
  • A to G, chromosome 4 at 28,935,826 bp
  • T to C, chromosome 4 at 84,884,700 bp
  • A to C, chromosome 4 at 99,657,325 bp
  • A to T, chromosome 4 at 109,665,038 bp
  • C to G, chromosome 4 at 148,901,291 bp
  • T to A, chromosome 5 at 21,582,067 bp
  • A to T, chromosome 5 at 120,481,651 bp
  • A to T, chromosome 5 at 134,496,241 bp
  • G to C, chromosome 5 at 136,697,971 bp
  • A to G, chromosome 5 at 149,187,778 bp
  • T to C, chromosome 6 at 66,731,899 bp
  • T to C, chromosome 6 at 70,356,221 bp
  • T to A, chromosome 6 at 76,980,824 bp
  • T to C, chromosome 6 at 108,394,407 bp
  • C to A, chromosome 7 at 12,966,271 bp
  • T to A, chromosome 7 at 14,222,520 bp
  • G to A, chromosome 7 at 21,260,259 bp
  • A to G, chromosome 7 at 28,323,900 bp
  • T to A, chromosome 7 at 45,220,447 bp
  • T to A, chromosome 7 at 104,012,019 bp
  • A to T, chromosome 7 at 141,355,765 bp
  • T to A, chromosome 7 at 143,070,402 bp
  • T to G, chromosome 8 at 3,632,583 bp
  • T to C, chromosome 8 at 70,318,251 bp
  • G to A, chromosome 8 at 105,368,393 bp
  • T to C, chromosome 8 at 108,948,207 bp
  • T to C, chromosome 8 at 116,624,327 bp
  • C to T, chromosome 8 at 119,870,214 bp
  • A to T, chromosome 9 at 86,567,540 bp
  • C to T, chromosome 9 at 121,983,523 bp
  • C to A, chromosome 10 at 17,724,386 bp
  • T to A, chromosome 10 at 22,665,554 bp
  • T to A, chromosome 10 at 23,851,615 bp
  • T to C, chromosome 10 at 76,411,360 bp
  • A to G, chromosome 10 at 128,515,760 bp
  • A to G, chromosome 11 at 58,922,397 bp
  • C to T, chromosome 11 at 101,177,326 bp
  • T to C, chromosome 12 at 79,279,114 bp
  • T to C, chromosome 12 at 113,826,697 bp
  • T to C, chromosome 13 at 113,318,850 bp
  • T to A, chromosome 14 at 46,853,477 bp
  • T to C, chromosome 15 at 79,530,263 bp
  • A to G, chromosome 16 at 87,427,641 bp
  • C to A, chromosome 18 at 37,681,801 bp
  • A to G, chromosome 18 at 56,775,981 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7152 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045254-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.