Strain Name:
C57BL/6J-MtgxR9003Btlr/Mmmh
Stock Number:
068833-MU
Citation ID:
RRID:MMRRC_068833-MU
Other Names:
R9003 (G1)
Major Collection:

Strain Information

Plin2
Name: perilipin 2
Synonyms: adipophilin, ADPH, Adrp, Adfp
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11520
HGNC: HGNC:248
Homologene: 872
Mthfd1
Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
Synonyms: DCS, Mthfd, E430024A07Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 108156
VEGA: 12
HGNC: HGNC:7432
Homologene: 55940
Pum1
Name: pumilio RNA-binding family member 1
Synonyms: Pumm
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 80912
Homologene: 22830
Jak2
Name: Janus kinase 2
Synonyms: C81284
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 16452
VEGA: 19
HGNC: HGNC:6192
Homologene: 21033
Arid1a
Name: AT-rich interaction domain 1A
Synonyms: BAF250a, Osa1, Smarcf1, 1110030E03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 93760
Homologene: 21216
Exoc6
Name: exocyst complex component 6
Synonyms: hbd, Sec15, Sec15l1, 4833405E05Rik, msec15
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107371
VEGA: 19
Homologene: 41305
Cdca4
Name: cell division cycle associated 4
Synonyms: SEI-3, 2410018C03Rik, Hepp
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 71963
VEGA: 12
Homologene: 9936
Kif5b
Name: kinesin family member 5B
Synonyms: Khc, kinesin heavy chain
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 16573
HGNC: HGNC:6324
Homologene: 55829
Sbno2
Name: strawberry notch 2
Synonyms: Stno
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216161
VEGA: 10
Homologene: 8981
Akap12
Name: A kinase anchor protein 12
Synonyms: Tsga12, Srcs5, SSeCKS
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 83397
VEGA: 10
HGNC: HGNC:370
Homologene: 3740
Asf1b
Name: anti-silencing function 1B histone chaperone
Synonyms: 1700003K02Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66929
Homologene: 56797
Tut4
Name: terminal uridylyl transferase 4
Synonyms: Tent3a, 9230115F04Rik, Zcchc11, 6030404K05Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230594
Homologene: 35279
Plcg2
Name: phospholipase C, gamma 2
Synonyms: PLCgamma2, Plcg-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234779
HGNC: HGNC:9066
Homologene: 55671
Topbp1
Name: topoisomerase (DNA) II binding protein 1
Synonyms: D430026L04Rik, 1110031N14Rik, 2810429C13Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235559
Homologene: 38262
Stk39
Name: serine/threonine kinase 39
Synonyms: SPAK, DCHT, RF005, Rnl5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 53416
Homologene: 22739
Zbtb40
Name: zinc finger and BTB domain containing 40
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230848
Homologene: 8912
Gfm2
Name: G elongation factor, mitochondrial 2
Synonyms: EFG2, A930009M04Rik, MST027, 6530419G12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 320806
Homologene: 6238
Robo1
Name: roundabout guidance receptor 1
Synonyms: DUTT1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19876
Homologene: 2206
Cxxc4
Name: CXXC finger 4
Synonyms: Idax, 9330210J02Rik, C030003J12Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 319478
Homologene: 11878
Mecom
Name: MDS1 and EVI1 complex locus
Synonyms: Evi-1, Jbo, ZNFPR1B1, D630039M04Rik, Prdm3, Mds1, Evi1, MDS1-EVI1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14013
HGNC: HGNC:3498
Homologene: 21086
Pla2g4e
Name: phospholipase A2, group IVE
Synonyms: 2310026J01Rik, Pla2epsilon
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329502
Homologene: 65339
Atp10a
Name: ATPase, class V, type 10A
Synonyms: pfatp, Atp10c
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11982
Homologene: 56461
Cul9
Name: cullin 9
Synonyms: Parc, 1810035I07Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78309
Homologene: 56696
Eps8l1
Name: EPS8-like 1
Synonyms: DRC3, EPS8R1, 2310051G19Rik, 4632407K17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67425
Homologene: 15767
Fbn2
Name: fibrillin 2
Synonyms: Fib-2, sy, Sne
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 14119
VEGA: 18
HGNC: HGNC:3604
Homologene: 1515
Slc4a9
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 9
Synonyms: D630024F24Rik, AE4
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240215
VEGA: 18
Homologene: 23732
Madd
Name: MAP-kinase activating death domain
Synonyms: Rab3 GEP, 9630059K23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228355
HGNC: HGNC:6766
Homologene: 14249
Or5ac19
Name: olfactory receptor family 5 subfamily AC member 19
Synonyms: GA_x54KRFPKG5P-55483936-55483010, MOR182-2, Olfr201
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258996
Homologene: 37011
Ccdc146
Name: coiled-coil domain containing 146
Synonyms: 4930528G09Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75172
Homologene: 67159
Scarf1
Name: scavenger receptor class F, member 1
Synonyms: SREC, SREC-I
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380713
Homologene: 2741
Abcb5
Name: ATP-binding cassette, sub-family B member 5
Synonyms: 9230106F14Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 77706
HGNC: HGNC:46
Homologene: 83488
Sh3pxd2b
Name: SH3 and PX domains 2B
Synonyms: Fad49, Tks4, G431001E03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268396
Homologene: 27952
Sdcbp2
Name: syndecan binding protein (syntenin) 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228765
Homologene: 9240
Ttc28
Name: tetratricopeptide repeat domain 28
Synonyms: 2310015L07Rik, TPRBK
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 209683
Homologene: 41023
Vmn2r52
Name: vomeronasal 2, receptor 52
Synonyms: EG384534
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 384534
Homologene: 129605
Tmem168
Name: transmembrane protein 168
Synonyms: 8430437G11Rik, 5730526F17Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101118
Homologene: 11202
Clca3b
Name: chloride channel accessory 3B
Synonyms: Clca4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229927
HGNC: HGNC:2017
Homologene: 135610
Nek4
Name: NIMA (never in mitosis gene a)-related expressed kinase 4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 23955
VEGA: 14
Homologene: 2376
Cpb2
Name: carboxypeptidase B2
Synonyms: CPR, TAFI, thrombin-activatable fibrinolysis inhibitor, carboxypeptidase R, 4930405E17Rik, 1110032P04Rik, CPU, carboxypeptidase U
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56373
VEGA: 14
HGNC: HGNC:2300
Homologene: 55610
Rsbn1
Name: rosbin, round spermatid basic protein 1
Synonyms: C230004D03Rik, Rsbp
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229675
Homologene: 10154
Aurkc
Name: aurora kinase C
Synonyms: IAK3, Stk13, AIE1, AIK3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20871
Homologene: 68302
Coa8
Name: cytochrome c oxidase assembly factor 8
Synonyms: Apop-1, Apopt1, 2810002N01Rik, 1700081D05Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68020
Homologene: 12225
Smpdl3a
Name: sphingomyelin phosphodiesterase, acid-like 3A
Synonyms: ASM3A, 0610010C24Rik, ASML3A
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 57319
Homologene: 4886
Timm44
Name: translocase of inner mitochondrial membrane 44
Synonyms: 0710005E20Rik, Tim44, Mimt44, D8Ertd118e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 21856
Homologene: 4631
Ldhd
Name: lactate dehydrogenase D
Synonyms: 4733401P21Rik, D8Bwg1320e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 52815
Homologene: 5536
Carmil2
Name: capping protein regulator and myosin 1 linker 2
Synonyms: Rltpr, D130029J02Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234695
Homologene: 128439
Klhl22
Name: kelch-like 22
Synonyms: Kelchl, 2610318I18Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224023
Homologene: 23784
Or2y1b
Name: olfactory receptor family 2 subfamily Y member 1B
Synonyms: Olfr10, MOR256-55, GA_x6K02T2QP88-6117098-6116163, L45
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18307
Homologene: 81347
Tpp1
Name: tripeptidyl peptidase I
Synonyms: Cln2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12751
HGNC: HGNC:2073
Homologene: 335
Or10g3b
Name: olfactory receptor family 10 subfamily G member 3B
Synonyms: Olfr1513, MOR223-10, GA_x6K02T2RJGY-644134-645075, MOR223-7P
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258008
HGNC: HGNC:8171
Homologene: 79404
Tinf2
Name: Terf1 (TRF1)-interacting nuclear factor 2
Synonyms: D14Wsu146e, TIN2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 28113
VEGA: 14
Homologene: 8264
Chpt1
Name: choline phosphotransferase 1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 212862
Homologene: 69297
Or4k42
Name: olfactory receptor family 4 subfamily K member 42
Synonyms: Olfr1290, MOR248-9, GA_x6K02T2Q125-72541649-72540711
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257662
Homologene: 74248
Phc3
Name: polyhomeotic 3
Synonyms: EDR3, HPH3, E030046K01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 241915
Homologene: 69390
Acot4
Name: acyl-CoA thioesterase 4
Synonyms: PTE-Ib, B430212I04Rik, Pte2b
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 171282
Homologene: 44237
Or4c117
Name: olfactory receptor family 4 subfamily C member 117
Synonyms: MOR233-14, Olfr1222, GA_x6K02T2Q125-50604368-50603433
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258177
Homologene: 73988
Or8c18
Name: olfactory receptor family 8 subfamily C member 18
Synonyms: MOR170-10P, GA_x6K02T2PVTD-31985209-31986136, Olfr896
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258030
VEGA: 9
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 2 at 68,392,118 bp
  • T to A, chromosome 2 at 89,125,680 bp
  • C to A, chromosome 2 at 91,158,014 bp
  • A to G, chromosome 2 at 111,490,066 bp
  • T to A, chromosome 2 at 120,176,801 bp
  • G to A, chromosome 2 at 151,587,193 bp
  • G to A, chromosome 2 at 177,475,217 bp
  • T to C, chromosome 3 at 29,980,490 bp
  • G to A, chromosome 3 at 30,965,858 bp
  • T to C, chromosome 3 at 103,914,872 bp
  • A to T, chromosome 3 at 134,239,670 bp
  • C to T, chromosome 3 at 144,827,311 bp
  • T to C, chromosome 4 at 86,662,087 bp
  • A to G, chromosome 4 at 108,542,832 bp
  • T to G, chromosome 4 at 130,747,082 bp
  • T to C, chromosome 4 at 133,684,488 bp
  • G to T, chromosome 4 at 137,018,593 bp
  • T to C, chromosome 5 at 21,303,134 bp
  • G to A, chromosome 5 at 111,277,030 bp
  • A to T, chromosome 6 at 13,591,447 bp
  • G to T, chromosome 7 at 4,461,017 bp
  • T to A, chromosome 7 at 6,996,548 bp
  • A to T, chromosome 7 at 10,171,254 bp
  • T to A, chromosome 7 at 58,807,455 bp
  • T to A, chromosome 7 at 105,748,949 bp
  • A to G, chromosome 8 at 4,274,204 bp
  • G to T, chromosome 8 at 83,955,901 bp
  • A to G, chromosome 8 at 105,697,273 bp
  • T to C, chromosome 8 at 111,630,262 bp
  • C to T, chromosome 8 at 117,615,263 bp
  • C to T, chromosome 9 at 38,292,047 bp
  • T to C, chromosome 9 at 103,323,528 bp
  • A to G, chromosome 10 at 4,356,744 bp
  • A to G, chromosome 10 at 57,807,881 bp
  • A to T, chromosome 10 at 80,060,215 bp
  • A to G, chromosome 10 at 88,477,081 bp
  • T to C, chromosome 11 at 32,411,571 bp
  • C to T, chromosome 11 at 49,318,328 bp
  • A to T, chromosome 11 at 75,515,243 bp
  • C to T, chromosome 12 at 76,303,980 bp
  • A to G, chromosome 12 at 84,043,195 bp
  • A to G, chromosome 12 at 111,721,755 bp
  • A to G, chromosome 12 at 112,822,039 bp
  • G to A, chromosome 12 at 118,886,278 bp
  • T to G, chromosome 13 at 97,146,381 bp
  • C to T, chromosome 14 at 30,982,514 bp
  • T to A, chromosome 14 at 52,349,311 bp
  • T to C, chromosome 14 at 55,680,402 bp
  • A to T, chromosome 14 at 75,242,428 bp
  • T to C, chromosome 16 at 17,771,748 bp
  • A to T, chromosome 16 at 59,268,900 bp
  • A to G, chromosome 16 at 72,742,114 bp
  • A to G, chromosome 17 at 46,525,075 bp
  • A to G, chromosome 18 at 6,224,047 bp
  • A to G, chromosome 18 at 36,540,734 bp
  • T to C, chromosome 18 at 58,043,519 bp
  • A to T, chromosome 19 at 29,276,840 bp
  • T to C, chromosome 19 at 37,598,649 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9003 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068833-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.