Strain Name:
C57BL/6J-MtgxR0123Btlr/Mmmh
Stock Number:
038408-MU
Citation ID:
RRID:MMRRC_038408-MU
Other Names:
R0123 (G1), C57BL/6J-MtgxR0123Btlr
Major Collection:

Strain Information

Smarca4
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Synonyms: SNF2beta, Brg1, SW1/SNF, b2b692Clo, b2b508.1Clo
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20586
Homologene: 135927
Cacna1g
Name: calcium channel, voltage-dependent, T type, alpha 1G subunit
Synonyms: a1G, Cav3.1d
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12291
HGNC: HGNC:1394
Homologene: 22544
Becn1
Name: beclin 1, autophagy related
Synonyms: Atg6
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56208
HGNC: HGNC:1034
Homologene: 2794
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Acf7, Aclp7, trabeculin alpha
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11426
Homologene: 136191
Lhx9
Name: LIM homeobox protein 9
Synonyms: LH2B, Lhx9 alpha, 3110009O07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16876
Homologene: 7816
Ddx50
Name: DExD box helicase 50
Synonyms: GU2, RH-II/Gubeta, 4933429B04Rik, 8430408E17Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 94213
VEGA: 10
Homologene: 56986
Hira
Name: histone cell cycle regulator
Synonyms: Tuple1, D16Ertd95e, Gm15797
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 15260
HGNC: HGNC:4916
Homologene: 48172
Kif16b
Name: kinesin family member 16B
Synonyms: N-3 kinesin, 8430434E15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16558
Homologene: 135708
Phf3
Name: PHD finger protein 3
Synonyms: 2310061N19Rik, AU020177
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 213109
HGNC: HGNC:8921
Homologene: 9040
Btbd9
Name: BTB domain containing 9
Synonyms: 1700023F20Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224671
VEGA: 17
Homologene: 14995
Slc10a7
Name: solute carrier family 10 (sodium/bile acid cotransporter family), member 7
Synonyms: 2410193C02Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76775
Homologene: 81628
Bicd1
Name: BICD cargo adaptor 1
Synonyms: B830009D06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12121
HGNC: HGNC:1049
Homologene: 37518
Il3
Name: interleukin 3
Synonyms: Il-3, PSF, MCGF, HCGF, BPA, Csfmu
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16187
HGNC: HGNC:6011
Homologene: 49243
Tep1
Name: telomerase associated protein 1
Synonyms: Tp1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 21745
VEGA: 14
Homologene: 5157
Hdac2
Name: histone deacetylase 2
Synonyms: Yy1bp, D10Wsu179e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15182
HGNC: HGNC:4853
Homologene: 68187
1110059E24Rik
Name: RIKEN cDNA 1110059E24 gene
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66206
Homologene: 11933
Zfyve1
Name: zinc finger, FYVE domain containing 1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217695
VEGA: 12
Homologene: 10945
Itgb3
Name: integrin beta 3
Synonyms: platelet glycoprotein IIIa (GP3A), CD61
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16416
HGNC: HGNC:6156
Homologene: 55444
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 1810042B05Rik, Coh1, C330002D13Rik, 2310042E16Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Chn2
Name: chimerin 2
Synonyms: 1700026N20Rik, 4930557O16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 69993
HGNC: HGNC:1944
Homologene: 31213
Zfp982
Name: zinc finger protein 982
Synonyms: Gm13152
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 195531
Tpd52l1
Name: tumor protein D52-like 1
Synonyms: D53
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 21987
VEGA: 10
Homologene: 2468
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, 2610100B16Rik, Odz3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23965
Homologene: 22673
Lrch3
Name: leucine-rich repeats and calponin homology (CH) domain containing 3
Synonyms: LOC385628, 2210409B11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 70144
Homologene: 13111
Garnl3
Name: GTPase activating RANGAP domain-like 3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99326
Homologene: 13003
Abca16
Name: ATP-binding cassette, sub-family A member 16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233810
Homologene: 132942
Slc9a1
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 1
Synonyms: antiporter, Apnh, Nhe1, Nhe-1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20544
Homologene: 20660
Cd22
Name: CD22 antigen
Synonyms: Lyb-8, Lyb8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12483
HGNC: HGNC:1643
Homologene: 31052
Ell2
Name: elongation factor for RNA polymerase II 2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 192657
VEGA: 13
Homologene: 8094
Ttn
Name: titin
Synonyms: connectin, L56, 1100001C23Rik, mdm, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Nlgn1
Name: neuroligin 1
Synonyms: 6330415N05Rik, NL1, Nlg1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192167
Homologene: 56690
Cmya5
Name: cardiomyopathy associated 5
Synonyms: Myospryn, 2310076E16Rik, 2310076E21Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 76469
VEGA: 13
Homologene: 137367
Fhip2a
Name: FHF complex subunit HOOK interacting protein 2A
Synonyms: Fam160b1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226252
VEGA: 19
Homologene: 28133
Rimoc1
Name: RAB7A interacting MON1-CCZ1 complex subunit 1
Synonyms: AW549877
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 106064
VEGA: 15
Homologene: 27085
Siah2
Name: siah E3 ubiquitin protein ligase 2
Synonyms: Sinh2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20439
Homologene: 21053
Col5a2
Name: collagen, type V, alpha 2
Synonyms: 1110014L14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12832
HGNC: HGNC:2210
Homologene: 20119
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Pnp2
Name: purine-nucleoside phosphorylase 2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 667034
HGNC: HGNC:7892
Homologene: 227
Gata3
Name: GATA binding protein 3
Synonyms: Gata-3, jal
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14462
HGNC: HGNC:4172
Homologene: 1550
Mndal
Name: myeloid nuclear differentiation antigen like
Synonyms: Ifi212
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 100040462
HGNC: HGNC:5395
Homologene: 115929
Fam234b
Name: family with sequence similarity 234, member B
Synonyms: 8430419L09Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74525
Homologene: 12572
Jkampl
Name: JNK1/MAPK8 associated membrane protein like
Synonyms: 4931417E11Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 66740
Homologene: 75225
Nepn
Name: nephrocan
Synonyms: 5730521E12Rik, Npn, periolin
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66650
Homologene: 23549
Tas2r120
Name: taste receptor, type 2, member 120
Synonyms: mGR20, Tas2r20, T2R20, mt2r47
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387348
Homologene: 135705
Mug2
Name: murinoglobulin 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17837
HGNC: HGNC:9750
Homologene: 136663
Dnlz
Name: DNL-type zinc finger
Synonyms: 1110034G11Rik, D2Bwg1335e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 52838
Homologene: 36864
Or8k53
Name: olfactory receptor family 8 subfamily K member 53
Synonyms: GA_x6K02T2Q125-47819205-47818258, MOR186-1, Olfr1055
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 259023
Homologene: 131140
Cd59b
Name: CD59b antigen
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 333883
HGNC: HGNC:1689
Homologene: 56386
Rxfp1
Name: relaxin/insulin-like family peptide receptor 1
Synonyms: LOC381489, Lgr7
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 381489
Homologene: 11007
Efcab14
Name: EF-hand calcium binding domain 14
Synonyms: 4732418C07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230648
Homologene: 8858
Plekhn1
Name: pleckstrin homology domain containing, family N member 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 231002
VEGA: 4
Homologene: 12949
Vmn2r13
Name: vomeronasal 2, receptor 13
Synonyms: Gm4867
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231589
Homologene: 129606
Vmn1r45
Name: vomeronasal 1 receptor 45
Synonyms: V1r2, V1ra2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22297
Homologene: 130651
Zfp108
Name: zinc finger protein 108
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 54678
Homologene: 117959
Upk1a
Name: uroplakin 1A
Synonyms: Upk1, 1110031P12Rik, Tspan21
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 109637
Homologene: 21383
Or14a260
Name: olfactory receptor family 14 subfamily A member 260
Synonyms: GA_x6K02T2NHDJ-9772012-9772953, MOR219-1, Olfr307
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258610
Kctd21
Name: potassium channel tetramerisation domain containing 21
Synonyms: EG622320
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 622320
Homologene: 54754
Abraxas2
Name: BRISC complex subunit
Synonyms: C430003P19Rik, KIAA0157, Fam175b
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 109359
Homologene: 12970
Tsfm
Name: Ts translation elongation factor, mitochondrial
Synonyms: 9430024O13Rik, EF-Tsmt, EF-TS, 2310050B20Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66399
Homologene: 4184
Cts8
Name: cathepsin 8
Synonyms: Epcs70, Epcs68, CTS2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 56094
VEGA: 13
Homologene: 129897
Zswim8
Name: zinc finger SWIM-type containing 8
Synonyms: 4832404P21Rik, 2310021P13Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 268721
VEGA: 14
Homologene: 34313
Dlg5
Name: discs large MAGUK scaffold protein 5
Synonyms: 4933429D20Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 71228
HGNC: HGNC:2904
Homologene: 3486
Notch4
Name: notch 4
Synonyms: Int-3, Int3, N4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18132
HGNC: HGNC:7884
Homologene: 3351
Nrxn1
Name: neurexin I
Synonyms: alpha-latrotoxin receptor (calcium-dependent), neurexin I beta, neurexin I alpha, neurexin I beta, neurexin I beta, neurexin I alpha, neurexin I alpha, 1700062G21Rik, A230068P09Rik, 9330127H16Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18189
HGNC: HGNC:8008
Homologene: 21005
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 30,805,065 bp
  • A to G, chromosome 1 at 45,407,035 bp
  • A to T, chromosome 1 at 138,838,679 bp
  • A to T, chromosome 1 at 173,857,513 bp
  • T to C, chromosome 2 at 9,874,809 bp
  • T to C, chromosome 2 at 26,351,368 bp
  • T to C, chromosome 2 at 33,006,804 bp
  • T to C, chromosome 2 at 40,596,983 bp
  • T to A, chromosome 2 at 76,710,124 bp
  • C to A, chromosome 2 at 76,793,130 bp
  • T to C, chromosome 2 at 86,347,728 bp
  • G to A, chromosome 2 at 104,078,941 bp
  • A to T, chromosome 2 at 142,672,375 bp
  • C to T, chromosome 3 at 25,435,925 bp
  • A to G, chromosome 3 at 58,676,115 bp
  • A to G, chromosome 3 at 79,657,476 bp
  • T to C, chromosome 4 at 115,740,531 bp
  • T to C, chromosome 4 at 123,432,843 bp
  • A to G, chromosome 4 at 133,420,605 bp
  • A to T, chromosome 4 at 147,512,636 bp
  • T to C, chromosome 4 at 156,228,243 bp
  • C to A, chromosome 5 at 109,175,049 bp
  • T to C, chromosome 6 at 54,290,451 bp
  • A to G, chromosome 6 at 73,469,419 bp
  • A to T, chromosome 6 at 89,933,510 bp
  • G to T, chromosome 6 at 122,074,714 bp
  • T to A, chromosome 6 at 132,657,589 bp
  • T to G, chromosome 6 at 135,217,074 bp
  • T to C, chromosome 6 at 149,512,950 bp
  • A to G, chromosome 7 at 24,260,467 bp
  • A to T, chromosome 7 at 30,612,394 bp
  • A to G, chromosome 7 at 30,867,108 bp
  • A to G, chromosome 7 at 86,335,595 bp
  • T to A, chromosome 7 at 97,348,091 bp
  • T to A, chromosome 7 at 120,540,155 bp
  • G to A, chromosome 7 at 132,874,855 bp
  • A to T, chromosome 8 at 48,674,472 bp
  • T to A, chromosome 8 at 78,697,158 bp
  • T to C, chromosome 9 at 21,637,324 bp
  • A to G, chromosome 10 at 31,379,256 bp
  • T to A, chromosome 10 at 36,989,184 bp
  • A to T, chromosome 10 at 52,400,437 bp
  • A to T, chromosome 10 at 62,621,377 bp
  • A to G, chromosome 10 at 127,022,929 bp
  • A to G, chromosome 11 at 54,265,680 bp
  • T to A, chromosome 11 at 94,409,476 bp
  • A to G, chromosome 11 at 101,290,498 bp
  • A to T, chromosome 11 at 104,637,088 bp
  • A to G, chromosome 12 at 83,555,073 bp
  • T to A, chromosome 13 at 61,253,577 bp
  • T to C, chromosome 13 at 75,762,140 bp
  • A to G, chromosome 13 at 93,095,904 bp
  • T to C, chromosome 14 at 20,716,490 bp
  • T to C, chromosome 14 at 24,147,206 bp
  • C to T, chromosome 14 at 50,829,693 bp
  • T to C, chromosome 14 at 50,963,177 bp
  • T to C, chromosome 15 at 3,986,294 bp
  • T to C, chromosome 15 at 35,887,261 bp
  • T to A, chromosome 16 at 18,956,171 bp
  • T to A, chromosome 16 at 32,961,754 bp
  • C to T, chromosome 17 at 30,274,942 bp
  • C to T, chromosome 17 at 34,565,363 bp
  • A to T, chromosome 17 at 90,995,487 bp
  • T to C, chromosome 19 at 21,598,201 bp
  • G to A, chromosome 19 at 57,381,407 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0123 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038408-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.