Strain Name:
C57BL/6J-MtgxR2038Btlr/Mmmh
Stock Number:
040045-MU
Citation ID:
RRID:MMRRC_040045-MU
Other Names:
R2038 (G1), C57BL/6J-MtgxR2038Btlr
Major Collection:

Gene Information

Tln2
Name: talin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 70549
VEGA: 9
Homologene: 56692
Sptbn1
Name: spectrin beta, non-erythrocytic 1
Synonyms: non-erythrocytic, spectrin G, Spnb-2, Spnb2, beta fodrin, brain spectrin, elf3, elf1, 9930031C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20742
Homologene: 2354
Ppp1r1b
Name: protein phosphatase 1, regulatory inhibitor subunit 1B
Synonyms: Darpp32, DARPP-32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 19049
HGNC: HGNC:9287
Homologene: 12972
Mapk8
Name: mitogen-activated protein kinase 8
Synonyms: JNK1, c-Jun N-terminal kinase, Prkm8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 26419
HGNC: HGNC:6881
Homologene: 56760
Vps35l
Name: VPS35 endosomal protein sorting factor like
Synonyms: Vsp35l, 9030624J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 71517
Homologene: 10659
Zfp568
Name: zinc finger protein 568
Synonyms: LOC381866, chato
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243905
Homologene: 136307
Ttc27
Name: tetratricopeptide repeat domain 27
Synonyms: 2610511O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 74196
VEGA: 17
Homologene: 41191
Sfpq
Name: splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
Synonyms: 9030402K04Rik, 5730453G22Rik, 1110004P21Rik, D4Ertd314e, 2810416M14Rik, PSF, REP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 71514
Homologene: 3714
Kat7
Name: K(lysine) acetyltransferase 7
Synonyms: Hbo1, Hboa, Myst2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217127
Homologene: 5134
Ddx27
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228889
Homologene: 6431
Set
Name: SET nuclear oncogene
Synonyms: 5730420M11Rik, StF-IT-1, 2610030F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56086
Homologene: 55707
Slc33a1
Name: solute carrier family 33 (acetyl-CoA transporter), member 1
Synonyms: Acatn, D630022N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 11416
HGNC: HGNC:95
Homologene: 3476
2310022B05Rik
Name: RIKEN cDNA 2310022B05 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 69551
Homologene: 13120
Cd79a
Name: CD79A antigen (immunoglobulin-associated alpha)
Synonyms: mb-1, Ig-alpha, Igalpha, Cd79a, Ly54, Ig alpha, Ly-54, Iga
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12518
HGNC: HGNC:1698
Homologene: 31053
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 2310042E16Rik, Coh1, 1810042B05Rik, C330002D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230895
Homologene: 15583
Lman1
Name: lectin, mannose-binding, 1
Synonyms: MCFD1, P58, gp58, ERGIC53, MR60, F5F8D, 2610020P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 70361
HGNC: HGNC:6631
Homologene: 4070
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: 4432416O06Rik, DHC2, b2b414Clo, Dnchc2, m407Asp, m152Asp, D030010H02Rik, D330044F14Rik, DHC1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Taf4b
Name: TATA-box binding protein associated factor 4b
Synonyms: 105kDa, 2610524B04Rik, TAFII105, Taf2c2, 4932409F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 72504
VEGA: 18
Homologene: 28266
Nbeal1
Name: neurobeachin like 1
Synonyms: ALS2CR17, 2310076G13Rik, A530083I02Rik, A530050O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 269198
Homologene: 16453
Sez6l
Name: seizure related 6 homolog like
Synonyms: Acig1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56747
Homologene: 10895
Fhdc1
Name: FH2 domain containing 1
Synonyms: 6330505N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229474
Homologene: 18920
Cdh23
Name: cadherin 23 (otocadherin)
Synonyms: USH1D, mdfw, ahl, nmf112, nmf181, nmf252, 4930542A03Rik, sals, bob
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 22295
Homologene: 11142
Dhodh
Name: dihydroorotate dehydrogenase
Synonyms: 2810417D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 56749
HGNC: HGNC:2867
Homologene: 1043
Adgrf4
Name: adhesion G protein-coupled receptor F4
Synonyms: 4632435A09Rik, Gpr115
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78249
Homologene: 51953
Mlxipl
Name: MLX interacting protein-like
Synonyms: bHLHd14, WS-bHLH, Wbscr14, ChREBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 58805
Homologene: 32507
Scn7a
Name: sodium channel, voltage-gated, type VII, alpha
Synonyms: Nav2.3, 1110034K09Rik, Nax, Scn6a, Nav2, NaG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20272
Homologene: 55706
Astn1
Name: astrotactin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11899
HGNC: HGNC:773
Homologene: 7233
Esyt1
Name: extended synaptotagmin-like protein 1
Synonyms: Fam62a, Mbc2, vp115
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 23943
VEGA: 10
Homologene: 40794
Fsip1
Name: fibrous sheath-interacting protein 1
Synonyms: 4933432K11Rik, 1700012M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 71313
Homologene: 12390
Nrp1
Name: neuropilin 1
Synonyms: Npn1, NPN-1, NP-1, Neuropilin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 18186
HGNC: HGNC:8004
Homologene: 2876
H60b
Name: histocompatibility 60b
Synonyms: EG667281
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 667281
Homologene: 120804
Ppp4r4
Name: protein phosphatase 4, regulatory subunit 4
Synonyms: 8430415E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 74521
Homologene: 12571
Ninl
Name: ninein-like
Synonyms: LOC381388, LOC381387, 4930519N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 78177
Homologene: 57024
Olfr959
Name: olfactory receptor 959
Synonyms: GA_x6K02T2PVTD-33270211-33269276, MOR224-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258501
VEGA: 9
Homologene: 71989
Dmc1
Name: DNA meiotic recombinase 1
Synonyms: Dmc1, Mei11, Dmc1h, sgdp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 13404
VEGA: 15
HGNC: HGNC:2927
Homologene: 5135
Clpx
Name: caseinolytic mitochondrial matrix peptidase chaperone subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270166
HGNC: HGNC:2088
Homologene: 4851
Msh5
Name: mutS homolog 5
Synonyms: Mut5, G7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17687
HGNC: HGNC:7328
Homologene: 8415
Rad51ap2
Name: RAD51 associated protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 209550
VEGA: 12
Homologene: 85245
Vmn2r54
Name: vomeronasal 2, receptor 54
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 666085
Homologene: 104040
Tgfbrap1
Name: transforming growth factor, beta receptor associated protein 1
Synonyms: 3110018K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 73122
Homologene: 3141
Srrd
Name: SRR1 domain containing
Synonyms: Srr1, 2810002G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70118
Homologene: 33447
Hdac7
Name: histone deacetylase 7
Synonyms: Hdac7a, 5830434K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 56233
Homologene: 9124
H2-T10
Name: histocompatibility 2, T region locus 10
Synonyms: H-2T10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 15024
Olfr1240
Name: olfactory receptor 1240
Synonyms: MOR231-8, GA_x6K02T2Q125-50883183-50882239
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258804
Homologene: 121591
Dus2
Name: dihydrouridine synthase 2
Synonyms: Dus2l, 2310016K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 66369
Homologene: 6838
Ngb
Name: neuroglobin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 64242
Homologene: 10942
Msl2
Name: MSL complex subunit 2
Synonyms: Rnf184, Msl2l1, E130103E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 77853
Homologene: 10021
Mfhas1
Name: malignant fibrous histiocytoma amplified sequence 1
Synonyms: D8Ertd91e, 2310066G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 52065
Homologene: 3114
Glis1
Name: GLIS family zinc finger 1
Synonyms: GliH1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230587
Homologene: 77390
Olfr384
Name: olfactory receptor 384
Synonyms: Olfr386, GA_x6K02T2P1NL-3739520-3740032, GA_x6K02T2P1NL-3773152-3774090, MOR135-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 193053
Homologene: 105206
Hace1
Name: HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
Synonyms: 1700042J16Rik, A730034A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 209462
Homologene: 10807
Dynlrb2
Name: dynein light chain roadblock-type 2
Synonyms: 1700009A04Rik, Dncl2b, DNLC2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 75465
Homologene: 12601
Cdc34b
Name: cell division cycle 34B
Synonyms: Cdc34-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 111266
Col8a2
Name: collagen, type VIII, alpha 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 329941
HGNC: HGNC:2216
Homologene: 55879
Gm20521
Name: predicted gene 20521
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 43,054,634 bp
  • A to G, chromosome 1 at 60,206,344 bp
  • T to G, chromosome 1 at 158,657,120 bp
  • T to C, chromosome 2 at 30,070,200 bp
  • C to A, chromosome 2 at 66,737,436 bp
  • C to A, chromosome 2 at 89,439,345 bp
  • A to T, chromosome 2 at 118,249,795 bp
  • T to A, chromosome 2 at 150,975,843 bp
  • G to A, chromosome 2 at 167,033,755 bp
  • A to G, chromosome 3 at 63,948,156 bp
  • A to T, chromosome 3 at 84,444,561 bp
  • T to C, chromosome 4 at 107,623,242 bp
  • T to C, chromosome 4 at 126,311,315 bp
  • A to T, chromosome 4 at 127,021,502 bp
  • C to A, chromosome 4 at 145,181,115 bp
  • C to T, chromosome 5 at 112,338,450 bp
  • T to C, chromosome 5 at 112,472,752 bp
  • A to T, chromosome 5 at 135,106,999 bp
  • C to T, chromosome 7 at 12,629,710 bp
  • A to T, chromosome 7 at 24,899,357 bp
  • A to T, chromosome 7 at 29,989,082 bp
  • T to C, chromosome 7 at 118,811,874 bp
  • T to A, chromosome 8 at 35,591,277 bp
  • T to C, chromosome 8 at 106,048,662 bp
  • T to C, chromosome 8 at 109,595,078 bp
  • G to A, chromosome 8 at 116,514,810 bp
  • T to C, chromosome 8 at 124,663,023 bp
  • T to C, chromosome 8 at 128,431,886 bp
  • A to G, chromosome 9 at 6,967,226 bp
  • A to G, chromosome 9 at 39,572,987 bp
  • G to A, chromosome 9 at 65,317,493 bp
  • T to A, chromosome 9 at 67,397,653 bp
  • C to A, chromosome 9 at 101,101,984 bp
  • A to T, chromosome 10 at 22,286,215 bp
  • A to C, chromosome 10 at 45,700,625 bp
  • T to C, chromosome 10 at 60,312,587 bp
  • C to T, chromosome 10 at 128,511,951 bp
  • C to G, chromosome 11 at 30,159,293 bp
  • T to A, chromosome 11 at 73,603,413 bp
  • C to T, chromosome 11 at 94,742,288 bp
  • T to A, chromosome 11 at 95,300,102 bp
  • T to C, chromosome 11 at 98,356,961 bp
  • T to C, chromosome 12 at 11,457,024 bp
  • A to G, chromosome 12 at 87,100,125 bp
  • G to A, chromosome 12 at 103,576,280 bp
  • A to T, chromosome 14 at 33,388,936 bp
  • T to G, chromosome 14 at 54,897,152 bp
  • A to G, chromosome 15 at 35,884,741 bp
  • T to C, chromosome 15 at 79,562,591 bp
  • C to T, chromosome 15 at 97,798,270 bp
  • A to T, chromosome 17 at 30,758,281 bp
  • A to G, chromosome 17 at 35,046,040 bp
  • T to C, chromosome 17 at 36,119,425 bp
  • A to T, chromosome 17 at 42,667,863 bp
  • T to C, chromosome 17 at 74,856,502 bp
  • T to C, chromosome 18 at 14,807,399 bp
  • T to C, chromosome 18 at 65,998,610 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2038 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040045-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.