Strain Name:
C57BL/6J-MtgxR0239Btlr/Mmmh
Stock Number:
038477-MU
Citation ID:
RRID:MMRRC_038477-MU
Other Names:
R0239 (G1), C57BL/6J-MtgxR0239Btlr
Major Collection:

Strain Information

Ptk2
Name: PTK2 protein tyrosine kinase 2
Synonyms: FRNK, Fadk, FAK
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 14083
VEGA: 15
HGNC: HGNC:9611
Homologene: 7314
Lamb3
Name: laminin, beta 3
Synonyms: nicein, 125kDa
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16780
HGNC: HGNC:6490
Homologene: 191
Slc6a1
Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 1
Synonyms: XT-1, Xtrp1, Gabt1, Gat1, Gabt, GAT-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232333
Homologene: 2290
Dysf
Name: dysferlin
Synonyms: 2310004N10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 26903
HGNC: HGNC:3097
Homologene: 20748
Pzp
Name: PZP, alpha-2-macroglobulin like
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11287
Homologene: 104112
Orc1
Name: origin recognition complex, subunit 1
Synonyms: Orc1l, MmORC1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18392
HGNC: HGNC:8487
Homologene: 31221
Plxnd1
Name: plexin D1
Synonyms: 6230425C21Rik, b2b1863Clo, b2b553Clo
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67784
HGNC: HGNC:9107
Homologene: 22866
Zfp532
Name: zinc finger protein 532
Synonyms: C530030I18Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 328977
Homologene: 138627
Nf1
Name: neurofibromin 1
Synonyms: Mhdadsk9, neurofibromin, Nf-1, Dsk9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Depdc5
Name: DEP domain containing 5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 277854
Homologene: 34718
Nomo1
Name: nodal modulator 1
Synonyms: Nomo, D7Ertd156e, PM5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 211548
Homologene: 13810
Trip11
Name: thyroid hormone receptor interactor 11
Synonyms: GMAP-210, TRIP230, 3110031G15Rik, 6030460N08Rik, 2610511G22Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 109181
Homologene: 20897
Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Synonyms: b2b327Clo, opm, A630086P08Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 207304
VEGA: 12
Homologene: 9115
Dock4
Name: dedicator of cytokinesis 4
Synonyms: EST N28122, 6330411N01Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238130
VEGA: 12
Homologene: 56680
Mettl25
Name: methyltransferase like 25
Synonyms: BC067068
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216292
Homologene: 32774
Elp1
Name: elongator complex protein 1
Synonyms: C78473, Ikbkap, IKAP, 3110040G09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230233
HGNC: HGNC:5959
Homologene: 2699
Chmp7
Name: charged multivesicular body protein 7
Synonyms: 4930596K11Rik, CHMP family, member 7, 6330407G04Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105513
VEGA: 14
Homologene: 14613
Ash1l
Name: ASH1 like histone lysine methyltransferase
Synonyms: 8030453L17Rik, KMT2H, chromatin remodeling factor, E430018P19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192195
Homologene: 10225
Ipo9
Name: importin 9
Synonyms: Imp9, 0710008K06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226432
Homologene: 5874
Cd72
Name: CD72 antigen
Synonyms: Lyb-2, Ly-32, Ly-19, Ly-m19
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12517
HGNC: HGNC:1696
Homologene: 1350
Camta1
Name: calmodulin binding transcription activator 1
Synonyms: 1810059M14Rik, 2310058O09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100072
Homologene: 18942
Klc1
Name: kinesin light chain 1
Synonyms: Kns2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16593
HGNC: HGNC:6387
Homologene: 4056
Tmem131
Name: transmembrane protein 131
Synonyms: CC28, YR-23, D1Bwg0491e, Rw1, Neg, 2610524E03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 56030
Homologene: 32428
Pah
Name: phenylalanine hydroxylase
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18478
HGNC: HGNC:8582
Homologene: 234
Slc49a3
Name: solute carrier family 49 member 3
Synonyms: 4732482E20Rik, Mfsd7a, Mfsd7
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243197
VEGA: 5
Homologene: 49990
Map2
Name: microtubule-associated protein 2
Synonyms: MAP-2, G1-397-34, repro4, Mtap2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Vps51
Name: VPS51 GARP complex subunit
Synonyms: 3110057M17Rik, 1110014N23Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 68505
HGNC: HGNC:1172
Homologene: 34675
Alg8
Name: ALG8 alpha-1,3-glucosyltransferase
Synonyms: LOC381903
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381903
Homologene: 6931
Vac14
Name: Vac14 homolog (S. cerevisiae)
Synonyms: ingls, Trx, D8Wsu151e, Tax1bp2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234729
Homologene: 6528
Flcn
Name: folliculin
Synonyms: BHD, B430214A04Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216805
Homologene: 14583
Zfp599
Name: zinc finger protein 599
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235048
Homologene: 138456
Atp6v1c2
Name: ATPase, H+ transporting, lysosomal V1 subunit C2
Synonyms: 1110038G14Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68775
Homologene: 15866
Dnhd1
Name: dynein heavy chain domain 1
Synonyms: 8030491N06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77505
Homologene: 131117
Nacc2
Name: nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
Synonyms: Btbd14a, C030048H19Rik, 0610020I02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67991
Homologene: 75239
Sec31b
Name: SEC31 homolog B, COPII coat complex component
Synonyms: LOC240667, Sec31l2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240667
Homologene: 56708
Cfap70
Name: cilia and flagella associated protein 70
Synonyms: 5330402L21Rik, Ttc18
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 76670
Homologene: 17048
Slc35f4
Name: solute carrier family 35, member F4
Synonyms: 4930550L21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 75288
Homologene: 45939
Myh8
Name: myosin, heavy polypeptide 8, skeletal muscle, perinatal
Synonyms: Myhsp, Myhs-p, 4832426G23Rik, MyHC-pn
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17885
HGNC: HGNC:7578
Homologene: 68256
Cacna1d
Name: calcium channel, voltage-dependent, L type, alpha 1D subunit
Synonyms: Cchl1a2, Cav1.3alpha1, 8430418G19Rik, Cchl1a, D-LTCC, Cacnl1a2, C79217
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12289
VEGA: 14
HGNC: HGNC:1391
Homologene: 578
1110002E22Rik
Name: RIKEN cDNA 1110002E22 gene
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 102634333
Homologene: 131709
Trpm5
Name: transient receptor potential cation channel, subfamily M, member 5
Synonyms: Ltrpc5, Mtr1, 9430099A16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56843
Homologene: 22818
Ppfia4
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
Synonyms: LOC100042382, Gm3812, Liprin-alpha4, 1110008G13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68507
HGNC: HGNC:9248
Homologene: 66200
Cdh12
Name: cadherin 12
Synonyms: Br-cadherin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 215654
HGNC: HGNC:1751
Homologene: 37873
Hal
Name: histidine ammonia lyase
Synonyms: histidase, Hsd
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15109
HGNC: HGNC:4806
Homologene: 68229
Raet1c
Name: retinoic acid early transcript gamma
Synonyms: Rae1c, RAE-1gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Il4ra
Name: interleukin 4 receptor, alpha
Synonyms: IL-4 receptor alpha chain, CD124, Il4r
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16190
HGNC: HGNC:6015
Homologene: 7784
Col4a1
Name: collagen, type IV, alpha 1
Synonyms: Del(8)44H, Raw, Svc, Bru, alpha1(IV) collagen, Del(8)Bru44H, Col4a-1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12826
HGNC: HGNC:2202
Homologene: 20437
Myo3b
Name: myosin IIIB
Synonyms: A430065P19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329421
Homologene: 51393
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 628870
Homologene: 46008
Plekha4
Name: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
Synonyms: PEPP1, 2410005C22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69217
Homologene: 10848
Greb1l
Name: growth regulation by estrogen in breast cancer-like
Synonyms: mKIAA4095, AK220484
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 381157
Homologene: 73393
Ift140
Name: intraflagellar transport 140
Synonyms: Tce5, Wdtc2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106633
Homologene: 40979
Kif14
Name: kinesin family member 14
Synonyms: N-3 kinesin, D1Ertd367e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381293
Homologene: 8916
Atrnl1
Name: attractin like 1
Synonyms: Alp
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226255
VEGA: 19
Homologene: 45809
Espnl
Name: espin-like
Synonyms: LOC227357
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227357
Homologene: 77795
Nwd2
Name: NACHT and WD repeat domain containing 2
Synonyms: 3110047P20Rik, B830017A01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 319807
Homologene: 14974
Or52s1
Name: olfactory receptor family 52 subfamily S member 1
Synonyms: Olfr593, MOR24-2, GA_x6K02T2PBJ9-5927412-5928362
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258378
Homologene: 27147
Krt17
Name: keratin 17
Synonyms: Krt1-17, K17
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16667
HGNC: HGNC:6427
Homologene: 363
Zfp11
Name: zinc finger protein 11
Synonyms: Zfp-11, Krox-6
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22648
Homologene: 87241
Gemin6
Name: gem nuclear organelle associated protein 6
Synonyms: 2610019B15Rik, 2810470M17Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67242
Homologene: 11711
Or12e7
Name: olfactory receptor family 12 subfamily E member 7
Synonyms: Olfr1126, MOR264-5, GA_x6K02T2Q125-48959068-48960012
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258834
Homologene: 133659
Adra1d
Name: adrenergic receptor, alpha 1d
Synonyms: Adra-1, alpha1D-AR, Gpcr8, Adra1, Adra1a
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11550
HGNC: HGNC:280
Homologene: 551
Slc52a3
Name: solute carrier protein family 52, member 3
Synonyms: 2310046K01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69698
Homologene: 12324
Cdx2
Name: caudal type homeobox 2
Synonyms: Cdx-2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12591
HGNC: HGNC:1806
Homologene: 968
Irag2
Name: inositol 1,4,5-triphosphate receptor associated 2
Synonyms: D6Int5, Jaw1, Lrmp, D6Int7, D6Int8, D6Int4, D6Int3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16970
HGNC: HGNC:6690
Homologene: 4483
Or2ag1b
Name: olfactory receptor family 2 subfamily AG member 1B
Synonyms: GA_x6K02T2PBJ9-9067220-9066273, MOR283-9, Olfr694
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258444
Homologene: 79345
Tmem63c
Name: transmembrane protein 63c
Synonyms: 9330187M14Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217733
Homologene: 33129
Micu2
Name: mitochondrial calcium uptake 2
Synonyms: 4833427E09Rik, 1110008L20Rik, Efha1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 68514
VEGA: 14
Homologene: 12516
Nubp2
Name: nucleotide binding protein 2
Synonyms: D17Wsu11e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 26426
VEGA: 17
HGNC: HGNC:8042
Homologene: 8057
Pga5
Name: pepsinogen 5, group I
Synonyms: Pepf, 1110035E17Rik, pepsinogen A5
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 58803
VEGA: 19
Homologene: 105932
Mrrf
Name: mitochondrial ribosome recycling factor
Synonyms: 2400002D02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67871
HGNC: HGNC:7234
Homologene: 12203
Scai
Name: suppressor of cancer cell invasion
Synonyms: A930041I02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 320271
Homologene: 15523
Slc35c2
Name: solute carrier family 35, member C2
Synonyms: Ovcov1, D2Wsu58e, CGI-15
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228875
Homologene: 6581
Sirpd
Name: signal regulatory protein delta
Synonyms: Gm9733
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 751864
Homologene: 135594
D3Ertd751e
Name: DNA segment, Chr 3, ERATO Doi 751, expressed
Synonyms: 4930415G15Rik, 2810009O15Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 73852
Homologene: 12520
Tmem79
Name: transmembrane protein 79
Synonyms: mattrin, ma, 2310042N02Rik, Matt, 2310074C17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71913
Homologene: 11492
Gm5773
Name: predicted pseudogene 5773
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 436563
Hyal5
Name: hyaluronoglucosaminidase 5
Synonyms: 4933439A12Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74468
Homologene: 50610
Scgb1b2
Name: secretoglobin, family 1B, member 2
Synonyms: Abpa2, Scgb1b1, lacrimal gland protein, Apbh, LGP, Abph, Mja1l
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57426
Homologene: 114479
Tsnaxip1
Name: translin-associated factor X (Tsnax) interacting protein 1
Synonyms: TXI1, 1700016K08Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72236
Homologene: 10194
Kbtbd3
Name: kelch repeat and BTB (POZ) domain containing 3
Synonyms: 2200003A07Rik, Bklhd3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69149
Homologene: 12300
Ube2q2
Name: ubiquitin-conjugating enzyme E2Q family member 2
Synonyms: 3010021M21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 109161
Homologene: 45455
Nipal4
Name: NIPA-like domain containing 4
Synonyms: 9530066K23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 214112
Homologene: 133769
Tbc1d31
Name: TBC1 domain family, member 31
Synonyms: LOC210544, Wdr67, D330013L20Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 210544
Homologene: 17089
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 36,828,050 bp
  • A to G, chromosome 1 at 66,416,106 bp
  • T to C, chromosome 1 at 91,322,287 bp
  • T to C, chromosome 1 at 134,329,189 bp
  • A to G, chromosome 1 at 135,404,336 bp
  • A to G, chromosome 1 at 136,527,393 bp
  • A to T, chromosome 1 at 193,321,053 bp
  • T to G, chromosome 2 at 26,062,261 bp
  • T to C, chromosome 2 at 36,177,281 bp
  • T to A, chromosome 2 at 39,075,042 bp
  • T to A, chromosome 2 at 70,105,425 bp
  • T to C, chromosome 2 at 87,458,037 bp
  • C to A, chromosome 2 at 131,546,214 bp
  • T to C, chromosome 2 at 152,008,156 bp
  • C to T, chromosome 2 at 165,280,837 bp
  • A to G, chromosome 3 at 15,296,601 bp
  • A to G, chromosome 3 at 41,753,878 bp
  • A to G, chromosome 3 at 88,333,321 bp
  • A to G, chromosome 3 at 89,067,222 bp
  • A to G, chromosome 3 at 93,774,032 bp
  • TTCCTCCTCCTCCTCCTCCTCC to TTCCTCCTCCTCCTCCTCC, chromosome 3 at 138,065,834 bp
  • A to G, chromosome 4 at 43,453,163 bp
  • C to A, chromosome 4 at 56,784,596 bp
  • T to C, chromosome 4 at 108,595,646 bp
  • A to G, chromosome 4 at 151,143,730 bp
  • T to C, chromosome 5 at 32,943,240 bp
  • A to T, chromosome 5 at 63,800,124 bp
  • G to T, chromosome 5 at 108,444,016 bp
  • C to T, chromosome 5 at 129,658,238 bp
  • G to T, chromosome 5 at 147,303,287 bp
  • T to A, chromosome 6 at 24,876,344 bp
  • C to T, chromosome 6 at 84,064,479 bp
  • G to A, chromosome 6 at 114,302,800 bp
  • G to T, chromosome 6 at 115,968,793 bp
  • C to T, chromosome 6 at 128,489,156 bp
  • G to A, chromosome 6 at 145,171,978 bp
  • T to A, chromosome 7 at 31,291,730 bp
  • A to G, chromosome 7 at 45,532,358 bp
  • T to C, chromosome 7 at 46,079,594 bp
  • A to T, chromosome 7 at 97,383,684 bp
  • G to A, chromosome 7 at 103,212,726 bp
  • A to G, chromosome 7 at 105,721,531 bp
  • A to G, chromosome 7 at 106,689,255 bp
  • T to C, chromosome 7 at 125,575,199 bp
  • G to T, chromosome 7 at 143,082,958 bp
  • C to T, chromosome 8 at 11,218,780 bp
  • T to A, chromosome 8 at 105,844,488 bp
  • A to T, chromosome 8 at 110,635,375 bp
  • G to T, chromosome 9 at 4,330,144 bp
  • C to T, chromosome 9 at 22,249,759 bp
  • T to C, chromosome 9 at 55,163,007 bp
  • C to A, chromosome 10 at 22,180,862 bp
  • C to T, chromosome 10 at 87,567,281 bp
  • T to C, chromosome 10 at 93,503,482 bp
  • C to T, chromosome 10 at 105,826,525 bp
  • T to A, chromosome 10 at 107,806,696 bp
  • A to G, chromosome 11 at 46,150,441 bp
  • T to C, chromosome 11 at 59,801,076 bp
  • A to G, chromosome 11 at 67,301,692 bp
  • A to T, chromosome 11 at 79,418,574 bp
  • G to A, chromosome 11 at 100,260,878 bp
  • C to A, chromosome 12 at 17,294,675 bp
  • G to T, chromosome 12 at 40,737,540 bp
  • T to A, chromosome 12 at 51,769,318 bp
  • T to C, chromosome 12 at 87,075,639 bp
  • C to T, chromosome 12 at 101,884,728 bp
  • A to G, chromosome 12 at 111,785,324 bp
  • A to C, chromosome 14 at 20,448,605 bp
  • A to G, chromosome 14 at 30,123,496 bp
  • A to T, chromosome 14 at 49,304,256 bp
  • G to A, chromosome 14 at 57,917,378 bp
  • A to G, chromosome 14 at 69,720,997 bp
  • T to C, chromosome 15 at 21,586,407 bp
  • C to A, chromosome 15 at 57,940,753 bp
  • A to T, chromosome 15 at 73,343,283 bp
  • T to C, chromosome 17 at 24,884,471 bp
  • C to A, chromosome 17 at 25,045,523 bp
  • C to A, chromosome 17 at 80,225,710 bp
  • C to T, chromosome 18 at 10,458,567 bp
  • A to T, chromosome 18 at 65,682,985 bp
  • G to T, chromosome 19 at 6,071,437 bp
  • A to G, chromosome 19 at 10,669,453 bp
  • G to A, chromosome 19 at 44,525,469 bp
  • T to A, chromosome 19 at 57,682,359 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0239 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038477-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.