Strain Name:
C57BL/6J-MtgxR4729Btlr/Mmmh
Stock Number:
041603-MU
Citation ID:
RRID:MMRRC_041603-MU
Other Names:
R4729 (G1), C57BL/6J-MtgxR4729Btlr
Major Collection:

Strain Information

Pde1c
Name: phosphodiesterase 1C
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18575
HGNC: HGNC:8776
Homologene: 3682
Ank2
Name: ankyrin 2, brain
Synonyms: ankyrin B, Gm4392, Ankyrin-B, Ank-2, Ankyrin-2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Atic
Name: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Synonyms: 2610509C24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108147
HGNC: HGNC:794
Homologene: 2983
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Strn
Name: striatin, calmodulin binding protein
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268980
Homologene: 2380
Slit1
Name: slit guidance ligand 1
Synonyms: Slil1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20562
Homologene: 2302
Mad1l1
Name: MAD1 mitotic arrest deficient 1-like 1
Synonyms: Mad1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 17120
HGNC: HGNC:6762
Homologene: 74500
Mbtps1
Name: membrane-bound transcription factor peptidase, site 1
Synonyms: subtilisin/kexin isozyme-1, S1P, site-1 protease, SKI-1, 0610038M03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 56453
Homologene: 2808
Rad54l2
Name: RAD54 like 2 (S. cerevisiae)
Synonyms: Srisnf2l, G630026H09Rik, Arip4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 81000
Homologene: 56698
E2f2
Name: E2F transcription factor 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242705
HGNC: HGNC:3114
Homologene: 48264
Llgl2
Name: LLGL2 scribble cell polarity complex component
Synonyms: 9130006H11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217325
HGNC: HGNC:6629
Homologene: 3323
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Phr1, C130061D10Rik, Pam
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105689
Homologene: 9005
Tmem199
Name: transmembrane protein 199
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 195040
Homologene: 45125
Dido1
Name: death inducer-obliterator 1
Synonyms: dido, 6720461J16Rik, DIO-1, C130092D22Rik, Datf1, D130048F08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 23856
HGNC: HGNC:2680
Homologene: 34139
Snrnp200
Name: small nuclear ribonucleoprotein 200 (U5)
Synonyms: Ascc3l1, A330064G03Rik, HELIC2, U5-200KD
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 320632
Homologene: 5859
Zeb1
Name: zinc finger E-box binding homeobox 1
Synonyms: Tw, Zfhx1a, Zfx1a, Zfhep, Tcf18, MEB1, Nil2, 3110032K11Rik, Tcf8, AREB6, ZEB, [delta]EF1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 21417
Homologene: 31779
Myo18a
Name: myosin XVIIIA
Synonyms: MyoPDZ
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 360013
Homologene: 7977
Nav2
Name: neuron navigator 2
Synonyms: Rainb1, POMFIL2, Unc53H2, 5330421F07Rik, HELAD1, RAINB2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 78286
Homologene: 52330
Amt
Name: aminomethyltransferase
Synonyms: EG434437
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 434437
HGNC: HGNC:473
Homologene: 409
Dennd10
Name: DENN domain containing 10
Synonyms: Fam45a, 1810055E12Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 67894
Homologene: 10217
Fam83h
Name: family with sequence similarity 83, member H
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105732
VEGA: 15
Homologene: 15890
Trim66
Name: tripartite motif-containing 66
Synonyms: Tif1d, D7H11orf29
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330627
Homologene: 28044
Zfp719
Name: zinc finger protein 719
Synonyms: 9430094P17Rik, mszf6, C630016O21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210105
Vps18
Name: VPS18 CORVET/HOPS core subunit
Synonyms: 9930024E13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228545
Homologene: 13302
Iars2
Name: isoleucine-tRNA synthetase 2, mitochondrial
Synonyms: 2010002H18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381314
Homologene: 7118
Scn10a
Name: sodium channel, voltage-gated, type X, alpha
Synonyms: Nav1.8
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20264
VEGA: 9
Homologene: 21300
Pfas
Name: phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
Synonyms: 4432409B16Rik, Sofa
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237823
HGNC: HGNC:8863
Homologene: 5970
Inpp5j
Name: inositol polyphosphate 5-phosphatase J
Synonyms: Pib5pa, Pipp
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 170835
HGNC: HGNC:8956
Homologene: 8682
Dnajc1
Name: DnaJ heat shock protein family (Hsp40) member C1
Synonyms: Dnajl1, D230036H06Rik, MTJ1, ERdj1, 4733401K02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13418
Homologene: 7293
Riok3
Name: RIO kinase 3
Synonyms: 1200013N13Rik, D18Ertd331e, Sudd, E130306C24Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 66878
VEGA: 18
Homologene: 2843
Csnk1g2
Name: casein kinase 1, gamma 2
Synonyms: 2810429I12Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103236
VEGA: 10
HGNC: HGNC:2455
Homologene: 100845
Hectd3
Name: HECT domain E3 ubiquitin protein ligase 3
Synonyms: 1700064K09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76608
Homologene: 18426
Ice1
Name: interactor of little elongation complex ELL subunit 1
Synonyms: BC018507
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218333
VEGA: 13
Homologene: 18902
Irf8
Name: interferon regulatory factor 8
Synonyms: IRF-8, Myls, ICSBP, Icsbp1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 15900
HGNC: HGNC:5358
Homologene: 1629
Elfn1
Name: leucine rich repeat and fibronectin type III, extracellular 1
Synonyms: A930017N06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243312
Homologene: 18465
Rdh9
Name: retinol dehydrogenase 9
Synonyms: Crad3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103142
Homologene: 129514
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh4, Zfh-4, C130041O22Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80892
Homologene: 23477
Cacna1c
Name: calcium channel, voltage-dependent, L type, alpha 1C subunit
Synonyms: D930026N18Rik, (alpha)1 subunit, Cchl1a1, Cav1.2, L-type Cav1.2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12288
HGNC: HGNC:1390
Homologene: 55484
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: b2b1554Clo, A2mr, CD91
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Ip3r2, Itpr5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Klhl1
Name: kelch-like 1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 93688
HGNC: HGNC:6352
Homologene: 56903
Galns
Name: galactosamine (N-acetyl)-6-sulfatase
Synonyms: N-acetylgalactosamine-6-sulfate sulfatase
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 50917
HGNC: HGNC:4122
Homologene: 55468
Naip5
Name: NLR family, apoptosis inhibitory protein 5
Synonyms: Naip-rs3, Lgn1, Birc1e
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17951
HGNC: HGNC:7634
Homologene: 113589
Pcdhb11
Name: protocadherin beta 11
Synonyms: PcdhbK, Pcdhb5E
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93882
HGNC: HGNC:8690
Homologene: 62178
Neb
Name: nebulin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Gml2
Name: glycosylphosphatidylinositol anchored molecule like 2
Synonyms: Hemt1, hematopoietic cell-specific transcript, HemT, 1700057K19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 15202
HGNC: HGNC:4375
Homologene: 48071
Pard3b
Name: par-3 family cell polarity regulator beta
Synonyms: PAR3beta, Als2cr19, PAR3L, 1810008K04Rik, PAR3B, 2010002N16Rik, 2810455B10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 72823
Homologene: 35389
Slco1a1
Name: solute carrier organic anion transporter family, member 1a1
Synonyms: Oatp1, Oatp1a1, Slc21a1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 28248
Homologene: 137261
Kcnq4
Name: potassium voltage-gated channel, subfamily Q, member 4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 60613
HGNC: HGNC:6298
Homologene: 78107
BC034090
Name: cDNA sequence BC034090
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 207792
Homologene: 19490
4930562C15Rik
Name: RIKEN cDNA 4930562C15 gene
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78809
Homologene: 53527
Vars2
Name: valyl-tRNA synthetase 2, mitochondrial
Synonyms: 1190004I24Rik, Vars2l
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68915
Homologene: 57502
Erich6
Name: glutamate rich 6
Synonyms: Fam194a, 4932431H17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 545527
Homologene: 65043
Upk3bl
Name: uroplakin 3B-like
Synonyms: 2310043J07Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69665
Homologene: 78581
Lrrk1
Name: leucine-rich repeat kinase 1
Synonyms: D130026O16Rik, C230002E15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233328
Homologene: 23464
Krt76
Name: keratin 76
Synonyms: 2310001L23Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 77055
Homologene: 22931
Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
Synonyms: Adgrc3, flamingo, Fmi1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 107934
HGNC: HGNC:3230
Homologene: 1077
D630003M21Rik
Name: RIKEN cDNA D630003M21 gene
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228846
Homologene: 18598
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: 2900083P10Rik, C230094A16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237711
Homologene: 104282
Aox4
Name: aldehyde oxidase 4
Synonyms: 2310003G12Rik, AOH2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71872
Homologene: 70273
Vmn2r91
Name: vomeronasal 2, receptor 91
Synonyms: EG665210
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 665210
Homologene: 115024
Ankzf1
Name: ankyrin repeat and zinc finger domain containing 1
Synonyms: D1Ertd161e, 2810025E10Rik, 1300008P06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 52231
Homologene: 41225
Krt7
Name: keratin 7
Synonyms: Cytokeratin 7, K7, D15Wsu77e, Krt2-7
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110310
HGNC: HGNC:6445
Homologene: 4058
Lancl2
Name: LanC (bacterial lantibiotic synthetase component C)-like 2
Synonyms: 1700003F10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71835
HGNC: HGNC:6509
Homologene: 23116
Prr14
Name: proline rich 14
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233895
Homologene: 11424
Uap1
Name: UDP-N-acetylglucosamine pyrophosphorylase 1
Synonyms: ESTM38, AGX1, SPAG2, AgX
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 107652
Homologene: 2342
Rhag
Name: Rhesus blood group-associated A glycoprotein
Synonyms: CD241, Rh50A, Rh50
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19743
Homologene: 68045
Tmem101
Name: transmembrane protein 101
Synonyms: 2610511E22Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76547
Homologene: 12649
Cpne4
Name: copine IV
Synonyms: 4933406O10Rik, 3632411M23Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74020
HGNC: HGNC:2317
Homologene: 26078
Rnf7l
Name: ring finger protein 7 like
Synonyms: Gm7075
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 631906
VEGA: 10
Zfp677
Name: zinc finger protein 677
Synonyms: A830058L05Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 210503
Homologene: 138402
Rab11fip5
Name: RAB11 family interacting protein 5 (class I)
Synonyms: RIP11, GAF1, 9130206P09Rik, D6Ertd32e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 52055
Homologene: 9158
Snx31
Name: sorting nexin 31
Synonyms: 4631426E05Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66696
Homologene: 23551
1700088E04Rik
Name: RIKEN cDNA 1700088E04 gene
Synonyms: Mus EST J0827E04
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 27660
Homologene: 13062
Nme5
Name: NME/NM23 family member 5
Synonyms: 1700019D05Rik, non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase), Nm23-M5
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 75533
HGNC: HGNC:7853
Homologene: 2628
Fam78a
Name: family with sequence similarity 78, member A
Synonyms: A130092J06Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241303
Homologene: 14115
Pcbp4
Name: poly(rC) binding protein 4
Synonyms: 1200003L19Rik, AlphaCP-4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 59092
HGNC: HGNC:8652
Homologene: 56926
Gm9923
Name: predicted pseudogene 9923
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100040505
VEGA: 10
Hps4
Name: HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
Synonyms: Hermansky-Pudlak syndrome 4, BLOC-3, C130020P05Rik, 2010205O06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 192232
Homologene: 11123
Nradd
Name: neurotrophin receptor associated death domain
Synonyms: 2610311B09Rik, PLAIDD, NRDD
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67169
Homologene: 12091
Lrrc26
Name: leucine rich repeat containing 26
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227618
Homologene: 16228
Igkv12-38
Name: immunoglobulin kappa chain variable 12-38
Synonyms: Gm16690
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 620050
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 58,259,077 bp
  • A to G, chromosome 1 at 62,211,684 bp
  • C to T, chromosome 1 at 71,557,323 bp
  • T to A, chromosome 1 at 75,194,264 bp
  • T to A, chromosome 1 at 155,225,090 bp
  • T to C, chromosome 1 at 170,158,779 bp
  • A to G, chromosome 1 at 185,316,051 bp
  • A to G, chromosome 2 at 18,308,738 bp
  • A to T, chromosome 2 at 25,290,064 bp
  • T to C, chromosome 2 at 32,082,605 bp
  • A to G, chromosome 2 at 52,263,662 bp
  • G to T, chromosome 2 at 76,851,585 bp
  • C to T, chromosome 2 at 119,293,791 bp
  • A to T, chromosome 2 at 127,232,937 bp
  • A to G, chromosome 2 at 158,216,703 bp
  • G to T, chromosome 2 at 180,687,650 bp
  • G to T, chromosome 3 at 5,399,497 bp
  • A to G, chromosome 3 at 58,636,059 bp
  • G to C, chromosome 3 at 126,976,896 bp
  • G to A, chromosome 4 at 116,997,218 bp
  • G to T, chromosome 4 at 120,713,074 bp
  • T to A, chromosome 4 at 136,184,449 bp
  • A to T, chromosome 5 at 112,378,176 bp
  • T to C, chromosome 5 at 136,057,393 bp
  • T to G, chromosome 5 at 139,973,658 bp
  • T to A, chromosome 5 at 140,261,511 bp
  • T to A, chromosome 6 at 56,072,209 bp
  • T to C, chromosome 6 at 57,737,712 bp
  • T to A, chromosome 6 at 69,943,384 bp
  • C to T, chromosome 6 at 85,374,267 bp
  • A to T, chromosome 6 at 118,656,175 bp
  • G to T, chromosome 6 at 141,908,969 bp
  • A to G, chromosome 6 at 146,373,173 bp
  • T to A, chromosome 7 at 43,590,410 bp
  • T to A, chromosome 7 at 49,452,819 bp
  • T to A, chromosome 7 at 66,262,293 bp
  • A to G, chromosome 7 at 109,456,060 bp
  • A to G, chromosome 7 at 127,474,696 bp
  • C to T, chromosome 8 at 119,525,420 bp
  • T to C, chromosome 8 at 120,753,439 bp
  • C to T, chromosome 8 at 122,603,456 bp
  • C to A, chromosome 9 at 104,922,556 bp
  • T to C, chromosome 9 at 106,460,730 bp
  • A to T, chromosome 9 at 106,716,118 bp
  • T to A, chromosome 9 at 108,300,652 bp
  • A to C, chromosome 9 at 108,847,652 bp
  • T to C, chromosome 9 at 110,621,911 bp
  • A to G, chromosome 9 at 119,671,526 bp
  • A to T, chromosome 10 at 63,421,465 bp
  • A to G, chromosome 10 at 72,309,694 bp
  • T to C, chromosome 10 at 80,639,204 bp
  • G to T, chromosome 10 at 127,593,922 bp
  • A to G, chromosome 10 at 127,776,752 bp
  • T to C, chromosome 11 at 3,495,025 bp
  • T to A, chromosome 11 at 29,833,204 bp
  • T to C, chromosome 11 at 68,993,914 bp
  • T to G, chromosome 11 at 77,777,685 bp
  • C to G, chromosome 11 at 78,508,680 bp
  • C to T, chromosome 11 at 102,156,329 bp
  • T to C, chromosome 11 at 115,848,299 bp
  • G to A, chromosome 13 at 13,637,901 bp
  • T to C, chromosome 13 at 70,606,384 bp
  • G to A, chromosome 13 at 100,222,131 bp
  • A to G, chromosome 14 at 96,280,148 bp
  • C to T, chromosome 14 at 103,188,591 bp
  • G to A, chromosome 15 at 36,523,552 bp
  • G to T, chromosome 15 at 74,824,010 bp
  • A to G, chromosome 15 at 76,002,336 bp
  • A to G, chromosome 15 at 79,135,124 bp
  • A to G, chromosome 15 at 101,420,558 bp
  • G to T, chromosome 15 at 101,889,081 bp
  • T to A, chromosome 16 at 4,849,323 bp
  • T to A, chromosome 17 at 18,107,644 bp
  • T to A, chromosome 17 at 21,397,418 bp
  • A to G, chromosome 17 at 35,664,457 bp
  • G to T, chromosome 17 at 40,828,401 bp
  • A to G, chromosome 17 at 78,657,961 bp
  • C to T, chromosome 18 at 5,767,286 bp
  • T to A, chromosome 18 at 12,128,927 bp
  • C to T, chromosome 18 at 34,569,837 bp
  • C to T, chromosome 18 at 37,422,366 bp
  • T to A, chromosome 19 at 41,647,020 bp
  • T to A, chromosome 19 at 60,834,871 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4729 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041603-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.