Strain Name:
C57BL/6J-MtgxR7599Btlr/Mmmh
Stock Number:
045673-MU
Citation ID:
RRID:MMRRC_045673-MU
Other Names:
R7599 (G1)
Major Collection:

Strain Information

Ptprz1
Name: protein tyrosine phosphatase receptor type Z, polypeptide 1
Synonyms: PTPzeta, DSD-1-PG, phosphacan, RPTPz, Ptprz, Ptpz, Rptpbeta, PTPbeta
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Pmp22
Name: peripheral myelin protein 22
Synonyms: TRE002, Gas-3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18858
HGNC: HGNC:9118
Homologene: 7482
Ptpn14
Name: protein tyrosine phosphatase, non-receptor type 14
Synonyms: PTP36, OTTMUSG00000022087, C130080N23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19250
HGNC: HGNC:9647
Homologene: 3941
Hdac1
Name: histone deacetylase 1
Synonyms: HD1, RPD3, MommeD5
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 433759
HGNC: HGNC:4852
Homologene: 68426
Wnk1
Name: WNK lysine deficient protein kinase 1
Synonyms: Hsn2, Prkwnk1, 6430573H23Rik, EG406236
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232341
Homologene: 14253
Snapc3
Name: small nuclear RNA activating complex, polypeptide 3
Synonyms: 1810020H02Rik, E030018J20Rik, 5031401C21Rik, 4930558A07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 77634
Homologene: 31130
Kpna2
Name: karyopherin subunit alpha 2
Synonyms: m-importin-alpha-P1, Rch1, m-importin, Importin alpha, 2410044B12Rik, pendulin, importin alpha 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16647
HGNC: HGNC:6395
Homologene: 1708
Ppard
Name: peroxisome proliferator activator receptor delta
Synonyms: PPARdelta/beta, Peroxisome proliferator-activated receptor beta, Nr1c2, NUC1, PPAR-delta, Pparb/d, Pparb
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19015
HGNC: HGNC:9235
Homologene: 4544
Rabgap1
Name: RAB GTPase activating protein 1
Synonyms: Gapcena
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227800
Homologene: 49301
Rsf1
Name: remodeling and spacing factor 1
Synonyms: Hbxap, p325, XAP8, C030033M12Rik, 4832420A03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Dennd4c
Name: DENN domain containing 4C
Synonyms: 1700065A05Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329877
Homologene: 23057
Zfp26
Name: zinc finger protein 26
Synonyms: Zfp-26, Zfp81-rs1, KRAB15, Zfp70, mkr-3, 5033428C05Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22688
Homologene: 52318
Mlh3
Name: mutL homolog 3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217716
VEGA: 12
HGNC: HGNC:7128
Homologene: 91153
Tacc1
Name: transforming, acidic coiled-coil containing protein 1
Synonyms: 4833447E04Rik, Tacc1, B230378H13Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 320165
Homologene: 4575
Polr2e
Name: polymerase (RNA) II (DNA directed) polypeptide E
Synonyms: XAP4, 25kDa, RPB5
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66420
HGNC: HGNC:9192
Homologene: 2018
Slc39a2
Name: solute carrier family 39 (zinc transporter), member 2
Synonyms: F730005G13Rik, zip2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 214922
Homologene: 40957
Scube1
Name: signal peptide, CUB domain, EGF-like 1
Synonyms: 7330410C13Rik, A630023E24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 64706
Homologene: 11224
Arhgap23
Name: Rho GTPase activating protein 23
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 58996
Homologene: 104145
Gcnt2
Name: glucosaminyl (N-acetyl) transferase 2 (I blood group)
Synonyms: IGnTC, 5330430K10Rik, IGnTA, IGnTB, IGnT
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14538
VEGA: 13
HGNC: HGNC:4204
Homologene: 41535
Zfp410
Name: zinc finger protein 410
Synonyms: D12Ertd748e
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 52708
VEGA: 12
Homologene: 10918
Apba3
Name: amyloid beta precursor protein binding family A member 3
Synonyms: Mint-3, neuronal munc18-1-interacting protein 3, neuron-specific X11L2 protein, X11gamma, Mint 3, lin-10
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 57267
VEGA: 10
HGNC: HGNC:580
Homologene: 3591
Bpnt2
Name: 3'(2'), 5'-bisphosphate nucleotidase 2
Synonyms: Jaws, gPAPP, 1110001C20Rik, Impad1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242291
Homologene: 9852
Sec24b
Name: SEC24 homolog B, COPII coat complex component
Synonyms: SEC24
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99683
Homologene: 55968
Tbc1d32
Name: TBC1 domain family, member 32
Synonyms: C6orf170, b2b2284Clo, D630037F22Rik, Bromi
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 544696
VEGA: 10
Homologene: 51889
Bpifb1
Name: BPI fold containing family B, member 1
Synonyms: U46068, von Ebner minor salivary protein, LPlunc1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228801
Homologene: 50047
Mecom
Name: MDS1 and EVI1 complex locus
Synonyms: Evi-1, Jbo, ZNFPR1B1, D630039M04Rik, Prdm3, Mds1, Evi1, MDS1-EVI1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14013
HGNC: HGNC:3498
Homologene: 21086
Itgae
Name: integrin alpha E, epithelial-associated
Synonyms: CD103, alpha-E1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16407
HGNC: HGNC:6147
Homologene: 113560
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 665700
Homologene: 90772
Sall3
Name: spalt like transcription factor 3
Synonyms: Salt, Spalt, Msal, Msal-1, B130022O04Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 20689
VEGA: 18
Homologene: 18142
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, D12Ertd777e, diminished cone electroretinogram, Cpfl8, Nesp2g, dice, syne-2, 6820443O06Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 319565
Homologene: 56700
Efcab6
Name: EF-hand calcium binding domain 6
Synonyms: 4932408N08Rik, 4931407K02Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 77627
Homologene: 11259
Fer1l6
Name: fer-1 like family member 6
Synonyms: EG631797
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 631797
Homologene: 53396
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Hc
Name: hemolytic complement
Synonyms: C5, He, Hfib2, C5a
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15139
HGNC: HGNC:1331
Homologene: 20412
Samd3
Name: sterile alpha motif domain containing 3
Synonyms: LOC268288
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 268288
VEGA: 10
Homologene: 67991
Adamts3
Name: ADAM metallopeptidase with thrombospondin type 1 motif 3
Synonyms: 6330442E02Rik, 1100001H14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330119
HGNC: HGNC:219
Homologene: 8596
Ttc23l
Name: tetratricopeptide repeat domain 23-like
Synonyms: 4930401A09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75777
Homologene: 44907
Klkb1
Name: kallikrein B, plasma 1
Synonyms: Kal-3, PSA, Kal3, Klk3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16621
HGNC: HGNC:6371
Homologene: 68097
Zfp575
Name: zinc finger protein 575
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101544
Homologene: 45485
Qng1
Name: Q-nucleotide N-glycosylase 1
Synonyms: 2210016F16Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 70153
Homologene: 13005
Slc2a2
Name: solute carrier family 2 (facilitated glucose transporter), member 2
Synonyms: Glut2, Glut-2, liver-type glucose transporter
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20526
Homologene: 68047
L3mbtl1
Name: L3MBTL1 histone methyl-lysine binding protein
Synonyms: L3MBTL1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241764
Homologene: 41846
Golgb1
Name: golgin B1
Synonyms: 6330407A06Rik, Giantin, Gm6840, C130074L01Rik, F730017E11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224139
HGNC: HGNC:4429
Homologene: 68401
Fam234b
Name: family with sequence similarity 234, member B
Synonyms: 8430419L09Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74525
Homologene: 12572
Stat2
Name: signal transducer and activator of transcription 2
Synonyms: 1600010G07Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20847
VEGA: 10
Homologene: 3952
Nrxn3
Name: neurexin III
Synonyms: neurexin III beta, neurexin III alpha, D12Bwg0831e, neurexin III alpha, 9330112C09Rik, neurexin III beta, 4933401A11Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18191
HGNC: HGNC:8010
Homologene: 83225
Fanca
Name: Fanconi anemia, complementation group A
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14087
HGNC: HGNC:3582
Homologene: 108
Daam2
Name: dishevelled associated activator of morphogenesis 2
Synonyms: 2310016D11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 76441
VEGA: 17
Homologene: 69186
Or4a74
Name: olfactory receptor family 4 subfamily A member 74
Synonyms: Olfr1247, GA_x6K02T2Q125-51051555-51050611, MOR231-6
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258968
Homologene: 121536
St3gal6
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 6
Synonyms: ST3Gal VI, 1700023B24Rik, Siat10
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 54613
Homologene: 4448
Foxred1
Name: FAD-dependent oxidoreductase domain containing 1
Synonyms: TEG-23, Tex23
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235169
Homologene: 9712
Fdps
Name: farnesyl diphosphate synthetase
Synonyms: Fdpsl1, 6030492I17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 110196
HGNC: HGNC:3631
Homologene: 1519
Wdr35
Name: WD repeat domain 35
Synonyms: 4930459M12Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74682
Homologene: 10814
Slc5a9
Name: solute carrier family 5 (sodium/glucose cotransporter), member 9
Synonyms: SGLT4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230612
Homologene: 17081
Itgax
Name: integrin alpha X
Synonyms: Cd11c, CD11C (p150) alpha polypeptide, CR4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16411
HGNC: HGNC:6152
Homologene: 55493
Plekhg6
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 6
Synonyms: LOC213522
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213522
Homologene: 32395
Gabrg2
Name: gamma-aminobutyric acid type A receptor, subunit gamma 2
Synonyms: Gabrg-2, GABAA-R, gamma2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14406
HGNC: HGNC:4087
Homologene: 22443
Glyat
Name: glycine-N-acyltransferase
Synonyms: A330009E03Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107146
Homologene: 64840
Rmnd1
Name: required for meiotic nuclear division 1 homolog
Synonyms: 0610042C05Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66084
Homologene: 5675
Klk10
Name: kallikrein related-peptidase 10
Synonyms: NES1, 2300002A13Rik, PRSSL1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69540
HGNC: HGNC:6358
Homologene: 26428
Cyp2f2
Name: cytochrome P450, family 2, subfamily f, polypeptide 2
Synonyms: Cyp2f
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13107
Homologene: 73898
Zeb2
Name: zinc finger E-box binding homeobox 2
Synonyms: 9130203F04Rik, SIP1, Zfhx1b, Zfx1b, D130016B08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 24136
Homologene: 8868
Mcat
Name: malonyl CoA:ACP acyltransferase (mitochondrial)
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223722
VEGA: 15
Homologene: 15511
Mterf3
Name: mitochondrial transcription termination factor 3
Synonyms: 2410017I18Rik, Mterfd1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66410
Homologene: 9310
Retreg1
Name: reticulophagy regulator 1
Synonyms: Fam134b, 1810015C04Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66270
VEGA: 15
Homologene: 10368
Esrra
Name: estrogen related receptor, alpha
Synonyms: Estrra, ERRalpha, Err1, Nr3b1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 26379
HGNC: HGNC:3471
Homologene: 20941
Aqp6
Name: aquaporin 6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 11831
VEGA: 15
HGNC: HGNC:639
Homologene: 20399
Mesp2
Name: mesoderm posterior 2
Synonyms: bHLHc6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17293
Homologene: 7420
Slco4a1
Name: solute carrier organic anion transporter family, member 4a1
Synonyms: OATP-E, Slc21a12
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 108115
Homologene: 9482
Ccdc169
Name: coiled-coil domain containing 169
Synonyms: A730037C10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 320604
Homologene: 77607
Ucn2
Name: urocortin 2
Synonyms: Ucn-2, Urocortin II
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 171530
Homologene: 50048
Igkv8-26
Name: immunoglobulin kappa variable 8-26
Synonyms: Gm16945
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 620240
HGNC: HGNC:5834
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 189,850,745 bp
  • G to T, chromosome 2 at 31,356,286 bp
  • T to A, chromosome 2 at 35,050,419 bp
  • TGGGG to TGGG, chromosome 2 at 37,502,896 bp
  • C to T, chromosome 2 at 40,661,549 bp
  • T to G, chromosome 2 at 44,994,613 bp
  • T to A, chromosome 2 at 89,609,227 bp
  • T to C, chromosome 2 at 154,214,151 bp
  • A to C, chromosome 2 at 162,964,514 bp
  • T to C, chromosome 2 at 180,471,255 bp
  • A to G, chromosome 3 at 28,698,017 bp
  • T to C, chromosome 3 at 29,956,385 bp
  • A to G, chromosome 3 at 55,140,109 bp
  • G to T, chromosome 3 at 89,099,386 bp
  • TGC to TGCAGC, chromosome 3 at 130,040,811 bp
  • G to A, chromosome 4 at 4,778,207 bp
  • C to A, chromosome 4 at 83,417,836 bp
  • T to C, chromosome 4 at 86,811,612 bp
  • T to C, chromosome 4 at 111,877,740 bp
  • G to T, chromosome 4 at 129,517,466 bp
  • T to C, chromosome 5 at 89,861,397 bp
  • C to T, chromosome 6 at 23,002,519 bp
  • A to G, chromosome 6 at 70,193,587 bp
  • C to A, chromosome 6 at 119,929,828 bp
  • A to G, chromosome 6 at 125,374,660 bp
  • T to A, chromosome 6 at 135,226,876 bp
  • T to C, chromosome 7 at 24,586,668 bp
  • T to A, chromosome 7 at 27,131,359 bp
  • A to G, chromosome 7 at 43,784,427 bp
  • A to T, chromosome 7 at 79,810,969 bp
  • ATGGCG to ATGGCGACGGTGGCG, chromosome 7 at 97,579,904 bp
  • G to A, chromosome 7 at 128,148,090 bp
  • T to A, chromosome 8 at 25,201,285 bp
  • T to C, chromosome 8 at 45,278,113 bp
  • A to G, chromosome 8 at 123,271,260 bp
  • A to T, chromosome 9 at 20,437,833 bp
  • G to A, chromosome 9 at 35,205,636 bp
  • T to C, chromosome 9 at 108,986,224 bp
  • T to C, chromosome 10 at 4,413,404 bp
  • A to G, chromosome 10 at 26,263,813 bp
  • A to T, chromosome 10 at 56,151,833 bp
  • T to C, chromosome 10 at 80,038,570 bp
  • T to A, chromosome 10 at 81,272,346 bp
  • T to A, chromosome 10 at 128,277,197 bp
  • C to T, chromosome 11 at 41,967,624 bp
  • C to A, chromosome 11 at 63,158,348 bp
  • T to A, chromosome 11 at 73,121,960 bp
  • A to G, chromosome 11 at 97,500,343 bp
  • T to C, chromosome 11 at 106,998,757 bp
  • G to C, chromosome 12 at 9,024,886 bp
  • G to C, chromosome 12 at 75,966,371 bp
  • A to G, chromosome 12 at 84,331,856 bp
  • A to T, chromosome 12 at 85,268,199 bp
  • T to C, chromosome 12 at 89,512,062 bp
  • C to A, chromosome 13 at 40,860,867 bp
  • T to A, chromosome 13 at 58,381,835 bp
  • A to T, chromosome 13 at 66,917,148 bp
  • A to T, chromosome 14 at 51,895,031 bp
  • A to G, chromosome 15 at 10,533,680 bp
  • T to A, chromosome 15 at 25,971,641 bp
  • T to A, chromosome 15 at 58,627,589 bp
  • T to C, chromosome 15 at 83,547,671 bp
  • T to A, chromosome 15 at 83,613,452 bp
  • T to A, chromosome 15 at 83,870,988 bp
  • A to G, chromosome 15 at 99,603,771 bp
  • C to A, chromosome 16 at 36,875,396 bp
  • C to T, chromosome 16 at 58,473,437 bp
  • T to A, chromosome 17 at 28,297,117 bp
  • T to A, chromosome 17 at 49,480,727 bp
  • C to T, chromosome 18 at 80,972,052 bp
  • G to T, chromosome 19 at 6,913,846 bp
  • C to A, chromosome 19 at 12,639,808 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7599 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045673-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.